digraph workflow { graph [_draw_="c 9 -#fffffe00 C 7 -#eeeeee P 4 0 0 0 278 1003 278 1003 0 ", bb="0,0,1003,278", bgcolor="#eeeeee", clusterrank=local, color=black, dpi=96, fontsize=10, labeljust=left, nodesep=0.05, ranksep=0.22, xdotversion=1.7 ]; node [color=black, fillcolor=lightgoldenrodyellow, fontcolor=black, fontname=Helvetica, fontsize=10, height=0, label="\N", shape=record, style=filled, width=0 ]; edge [arrowsize=0.7, color=black, fontcolor=black, fontname=Helvetica, fontsize=8 ]; subgraph cluster_inputs { graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 8 215 8 270 995 270 995 215 ", _ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 58 258 0 84 15 -Workflow Inputs ", bb="8,215,995,270", label="Workflow Inputs", lheight=0.15, lp="58,260.5", lwidth=1.17, rank=same, style=dashed ]; resource_mills [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 899 223.5 899 242.5 987 242.5 987 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 943 230.5 0 72 14 -resource_mills ", fillcolor="#94DDF4", height=0.27778, label=resource_mills, pos="943,233", rects="899,223.5,987,242.5", width=1.2222]; snpf_genome [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 200.5 223.5 200.5 242.5 283.5 242.5 283.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 242 230.5 0 67 11 -snpf_genome ", fillcolor="#94DDF4", height=0.27778, label=snpf_genome, pos="242,233", rects="200.5,223.5,283.5,242.5", width=1.1528]; haplotest_vcf [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 811.5 223.5 811.5 242.5 894.5 242.5 894.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 853 230.5 0 67 13 -haplotest_vcf ", fillcolor="#94DDF4", height=0.27778, label=haplotest_vcf, pos="853,233", rects="811.5,223.5,894.5,242.5", width=1.1528]; snpf_data_dir [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 287.5 223.5 287.5 242.5 370.5 242.5 370.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 329 230.5 0 67 13 -snpf_data_dir ", fillcolor="#94DDF4", height=0.27778, label=snpf_data_dir, pos="329,233", rects="287.5,223.5,370.5,242.5", width=1.1528]; resource_omni [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 621.5 223.5 621.5 242.5 710.5 242.5 710.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 666 230.5 0 73 13 -resource_omni ", fillcolor="#94DDF4", height=0.27778, label=resource_omni, pos="666,233", rects="621.5,223.5,710.5,242.5", width=1.2361]; snp_mode [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 374.5 223.5 374.5 242.5 441.5 242.5 441.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 408 230.5 0 51 8 -snp_mode ", fillcolor="#94DDF4", height=0.27778, label=snp_mode, pos="408,233", rects="374.5,223.5,441.5,242.5", width=0.93056]; snpf_nodownload [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 94 223.5 94 242.5 196 242.5 196 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 145 230.5 0 86 15 -snpf_nodownload ", fillcolor="#94DDF4", height=0.27778, label=snpf_nodownload, pos="145,233", rects="94,223.5,196,242.5", width=1.4167]; reference [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 445.5 223.5 445.5 242.5 508.5 242.5 508.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 477 230.5 0 47 9 -reference ", fillcolor="#94DDF4", height=0.27778, label=reference, pos="477,233", rects="445.5,223.5,508.5,242.5", width=0.875]; resource_hapmap [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 513 223.5 513 242.5 617 242.5 617 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 565 230.5 0 88 15 -resource_hapmap ", fillcolor="#94DDF4", height=0.27778, label=resource_hapmap, pos="565,233", rects="513,223.5,617,242.5", width=1.4444]; resource_dbsnp [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 714.5 223.5 714.5 242.5 807.5 242.5 807.5 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 761 230.5 0 77 14 -resource_dbsnp ", fillcolor="#94DDF4", height=0.27778, label=resource_dbsnp, pos="761,233", rects="714.5,223.5,807.5,242.5", width=1.2917]; indel_mode [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 16 223.5 16 242.5 90 242.5 90 223.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 53 230.5 0 58 10 -indel_mode ", fillcolor="#94DDF4", height=0.27778, label=indel_mode, pos="53,233", rects="16,223.5,90,242.5", width=1.0278]; } subgraph cluster_outputs { graph [_draw_="S 6 -dashed c 7 -#000000 C 7 -#eeeeee P 4 359 8 359 63 537 63 537 8 ", _ldraw_="F 10 11 -Times-Roman c 7 -#000000 T 413 15 0 92 16 -Workflow Outputs ", bb="359,8,537,63", label="Workflow Outputs", labelloc=b, lheight=0.15, lp="413,17.5", lwidth=1.28, rank=same, style=dashed ]; recal_File [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 465.5 35.5 465.5 54.5 528.5 54.5 528.5 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 497 42.5 0 47 10 -recal_File ", fillcolor="#94DDF4", height=0.27778, label=recal_File, pos="497,45", rects="465.5,35.5,528.5,54.5", width=0.875]; annotated_snps [_draw_="c 7 -#000000 C 7 -#94ddf4 P 4 367 35.5 367 54.5 461 54.5 461 35.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 414 42.5 0 78 14 -annotated_snps ", fillcolor="#94DDF4", height=0.27778, label=annotated_snps, pos="414,45", rects="367,35.5,461,54.5", width=1.3056]; } snpeff_snps [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 292 80.5 292 99.5 366 99.5 366 80.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 329 87.5 0 58 11 -snpeff_snps ", height=0.27778, label=snpeff_snps, pos="329,90", rects="292,80.5,366,99.5", width=1.0278]; snpf_genome -> snpeff_snps [_draw_="c 7 -#000000 B 4 247.18 223.6 261.42 200.53 301.29 135.9 319.6 106.24 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 321.57 107.71 323.16 100.47 317.4 105.14 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 307 155.6 0 34 6 -genome ", label=genome, lp="307,157.5", pos="e,323.95,99.177 247.18,223.6 261.42,200.53 301.29,135.9 319.6,106.24"]; vqsr_snps [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 536.5 170.5 536.5 189.5 601.5 189.5 601.5 170.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 569 177.5 0 49 9 -vqsr_snps ", height=0.27778, label=vqsr_snps, pos="569,180", rects="536.5,170.5,601.5,189.5", width=0.90278]; haplotest_vcf -> vqsr_snps [_draw_="c 7 -#000000 B 10 830.78 223.6 811.71 216.4 787.26 207.14 787 207 781.16 203.79 781.23 200.37 775 198 745.76 186.9 660.85 183.03 \ 609.62 181.7 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 609.97 179.25 602.91 181.53 609.85 184.15 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 838.5 200.6 0 103 24 -haplotypecaller_snps_vcf ", label=haplotypecaller_snps_vcf, lp="838.5,202.5", pos="e,601.39,181.5 830.78,223.6 811.71,216.4 787.26,207.14 787,207 781.16,203.79 781.23,200.37 775,198 745.76,186.9 660.85,183.03 609.62,\ 181.7"]; apply_recalibration_snps [_draw_="c 7 -#000000 C 7 -#fafad2 P 4 400 125.5 400 144.5 538 144.5 538 125.5 ", _ldraw_="F 10 9 -Helvetica c 7 -#000000 T 469 132.5 0 122 24 -apply_recalibration_snps ", height=0.27778, label=apply_recalibration_snps, pos="469,135", rects="400,125.5,538,144.5", width=1.9167]; haplotest_vcf -> apply_recalibration_snps [_draw_="c 7 -#000000 B 7 870.85 223.67 882.78 216.99 894.96 207.23 887 198 843.86 147.99 654.62 137.66 546.14 135.93 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 546.37 133.48 539.34 135.83 546.31 138.38 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 892.5 178.1 0 31 7 -raw_vcf ", label=raw_vcf, lp="892.5,180", pos="e,537.83,135.81 870.85,223.67 882.78,216.99 894.96,207.23 887,198 843.86,147.99 654.62,137.66 546.14,135.93"]; snpf_data_dir -> snpeff_snps [_draw_="c 7 -#000000 B 4 329 223.6 329 200.82 329 137.55 329 107.39 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 331.45 107.69 329 100.69 326.55 107.69 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 346 155.6 0 34 8 -data_dir ", label=data_dir, lp="346,157.5", pos="e,329,99.177 329,223.6 329,200.82 329,137.55 329,107.39"]; resource_omni -> vqsr_snps [_draw_="c 7 -#000000 B 7 658.08 223.65 649.5 214.76 636.21 201.51 630 198 623.53 194.35 616.23 191.44 608.98 189.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 610.05 186.89 602.64 187.29 608.68 191.6 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 671.5 200.6 0 61 13 -resource_omni ", label=resource_omni, lp="671.5,202.5", pos="e,601.19,186.87 658.08,223.65 649.5,214.76 636.21,201.51 630,198 623.53,194.35 616.23,191.44 608.98,189.13"]; snp_mode -> apply_recalibration_snps [_draw_="c 7 -#000000 B 7 413.04 223.5 420.21 211.49 433.83 188.89 446 170 450.02 163.77 454.57 156.98 458.56 151.13 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 460.43 152.72 462.37 145.56 456.39 149.95 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 458 178.1 0 24 4 -mode ", label=mode, lp="458,180", pos="e,463.22,144.31 413.04,223.5 420.21,211.49 433.83,188.89 446,170 450.02,163.77 454.57,156.98 458.56,151.13"]; snpf_nodownload -> snpeff_snps [_draw_="c 7 -#000000 B 7 153.23 223.65 168.2 208.66 201.21 176.55 232 153 256.63 134.16 287.04 115.38 307.18 103.51 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 308.24 105.72 313.05 100.07 305.77 101.49 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 258 155.6 0 52 10 -nodownload ", label=nodownload, lp="258,157.5", pos="e,314.36,99.311 153.23,223.65 168.2,208.66 201.21,176.55 232,153 256.63,134.16 287.04,115.38 307.18,103.51"]; reference -> vqsr_snps [_draw_="c 7 -#000000 B 7 484.86 223.67 492.45 216.05 504.59 204.94 517 198 520.69 195.94 524.66 194.08 528.72 192.41 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 529.45 194.75 535.13 189.99 527.72 190.17 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 537 200.6 0 40 9 -reference ", label=reference, lp="537,202.5", pos="e,536.55,189.45 484.86,223.67 492.45,216.05 504.59,204.94 517,198 520.69,195.94 524.66,194.08 528.72,192.41"]; reference -> apply_recalibration_snps [_draw_="c 7 -#000000 B 7 476.27 223.81 475.12 210.74 472.82 184.37 471 162 470.75 158.93 470.49 155.65 470.25 152.5 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 472.7 152.5 469.73 145.71 467.82 152.87 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 493 178.1 0 40 9 -reference ", label=reference, lp="493,180", pos="e,469.61,144.2 476.27,223.81 475.12,210.74 472.82,184.37 471,162 470.75,158.93 470.49,155.65 470.25,152.5"]; resource_hapmap -> vqsr_snps [_draw_="c 7 -#000000 B 7 561.45 223.52 559.04 216.59 556.67 206.56 559 198 559.1 197.62 559.22 197.24 559.34 196.86 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 561.52 197.99 562.31 190.62 557.09 195.88 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 596 200.6 0 74 15 -resource_hapmap ", label=resource_hapmap, lp="596,202.5", pos="e,562.97,189.25 561.45,223.52 559.04,216.59 556.67,206.56 559,198 559.1,197.62 559.22,197.24 559.34,196.86"]; resource_dbsnp -> vqsr_snps [_draw_="c 7 -#000000 B 10 742.9 223.69 733.48 219.13 721.89 213.17 712 207 706.34 203.47 706.18 200.51 700 198 671.25 186.31 636.28 182.22 \ 609.7 180.98 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 609.99 178.54 602.9 180.72 609.81 183.43 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 745 200.6 0 66 14 -resource_dbsnp ", label=resource_dbsnp, lp="745,202.5", pos="e,601.39,180.66 742.9,223.69 733.48,219.13 721.89,213.17 712,207 706.34,203.47 706.18,200.51 700,198 671.25,186.31 636.28,182.22 \ 609.7,180.98"]; vqsr_snps -> recal_File [_draw_="c 7 -#000000 B 7 573.19 170.7 575.24 165.55 576.89 158.81 575 153 562.59 114.9 530.92 79.08 511.97 60.1 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 513.87 58.53 507.16 55.39 510.45 62.03 ", pos="e,506.08,54.327 573.19,170.7 575.24,165.55 576.89,158.81 575,153 562.59,114.9 530.92,79.082 511.97,60.098"]; vqsr_snps -> apply_recalibration_snps [_draw_="c 7 -#000000 B 7 536.87 174.49 512.89 170.86 483.52 165.77 479 162 475.91 159.42 473.77 155.77 472.29 152.02 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 474.7 151.52 470.41 145.47 469.99 152.87 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 505.5 155.6 0 53 13 -tranches_file ", label=tranches_file, lp="505.5,157.5", pos="e,470,144.01 536.87,174.49 512.89,170.86 483.52,165.77 479,162 475.91,159.42 473.77,155.77 472.29,152.02"]; vqsr_snps -> apply_recalibration_snps [_draw_="c 7 -#000000 B 10 554.59 170.62 550.17 167.95 545.33 164.93 541 162 535.48 158.27 534.97 155.96 529 153 524.48 150.76 519.62 148.77 \ 514.69 147.02 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 515.77 144.8 508.36 144.93 514.24 149.45 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 559.5 155.6 0 37 10 -recal_file ", label=recal_file, lp="559.5,157.5", pos="e,506.92,144.46 554.59,170.62 550.17,167.95 545.33,164.93 541,162 535.48,158.27 534.97,155.96 529,153 524.48,150.76 519.62,148.77 \ 514.69,147.02"]; snpeff_snps -> annotated_snps [_draw_="c 7 -#000000 B 4 345.79 80.5 358.37 74.14 375.75 65.35 389.82 58.23 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 390.75 60.51 395.89 55.16 388.54 56.13 ", pos="e,397.24,54.478 345.79,80.505 358.37,74.144 375.75,65.351 389.82,58.233"]; apply_recalibration_snps -> snpeff_snps [_draw_="c 7 -#000000 B 4 441.34 125.5 419.39 118.76 388.53 109.28 364.71 101.97 ", _hdraw_="S 5 -solid c 7 -#000000 C 7 -#000000 P 3 365.46 99.64 358.05 99.92 364.02 104.32 ", _ldraw_="F 8 9 -Helvetica c 7 -#000000 T 449 110.6 0 76 20 -variant_calling_file ", label=variant_calling_file, lp="449,112.5", pos="e,356.6,99.478 441.34,125.5 419.39,118.76 388.53,109.28 364.71,101.97"]; }