Ammar Ammar, ORCID:0000-0002-8399-8990

This maturity indicator falls under the FAIR principle R1.3: (meta)data meet domain-relevant community standards

The ID of this MI is composed of the following segments (separated by hyphen):

1. Acronym for "Maturity Indicator"
2. The FAIR principle this maturity indicator belongs to
3. The first 10 characters truncated from the SHA-256 hash of the primary reference DOI of this maturity indicator.
4. A short name to distinguish the maturity indicator definition file

This MI is to indicate if the ionic strength of the mammalian culture media (in liquid-surface exposure scenarios) is reported by the nano toxicity study data or not.

This maturity indicator is extracted from the following paper Title: Harmonizing Across Environmental Nanomaterial Testing Media for Increased Comparability of Nanomaterial Datasets DOI: https://doi.org/10.1039/C9EN00448C

R1.3

If the ionic strength of the mammalian culture media (in liquid-surface exposure scenarios) is reported by the nano toxicity study data or not.

The physiological ionic strength is between 100 to 200 mmol/L KCl or NaCl. Biomolecule protonisation and deprotonisation (e.g. binding and conversion of a substrate by the enzyme) depend on the ionic composition of the surrounding medium. Ionic strength is calculated from either reagent addition or from conductivity measurements.

If the value is measured and reported in the data, the following field(s) should appear in JSON-LD metadata:

The mammalian media ionic strength should be provided in a machine-readable format (JSON-LD) which can be queried using open universal protocol like HTTP.

The presence of the field "mammalian media ionic strength" in the JSON-LD metadata means the measurement is reported which is the valid result.

For nano toxicity related datasets.

{
 	"@context": {
 		"bs": "https://bioschemas.org/",
 		"schema": "https://schema.org/",
 		"citation": "schema:citation",
 		"name": "schema:name",
 		"url": "schema:url",
 		"variableMeasured": "schema:variableMeasured",
 		"unitText": "schema:unitText"
 	},
 	"@type": "schema:Dataset",
 	"name": "Dataset title",
 	"@id": "Dataset DOI",
 	"url": "Dataset URL",
 	"citation": "Dataset Citation/Publication",
 	"variableMeasured": [
 		{
 			"@type": "schema:PropertyValue",
 			"name": "mammalian media ionic strength"
 		}
 	]
 }