BiologicalProcess
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Biological Process
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Biological processes from Gene Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

BiologicalRole
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Biological Role
status: STANDARD
subclass of: RolesSchemaEnum
definition: Roles played by molecular entities within a biological context, dynamically populated from ChEBI. Includes biochemical roles, pharmacological roles, physiological roles, and other biological functions.
in scheme: merged
publishers: https://www.ebi.ac.uk/chebi
source domain: chemistry
source schema: roles
stewards: https://www.ebi.ac.uk/chebi

Cancer
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Neoplastic and cancerous diseases
in scheme: merged
source domain: bio
source schema: bio_entities

CellType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Cell Type
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Any cell type from the Cell Ontology (CL), including native and experimentally modified cells
in scheme: merged
source domain: bio
source schema: bio_entities

CellularComponent
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Cellular Component
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Cellular components and locations from Gene Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

ChemicalEntity
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Chemical Entity
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Any chemical entity from ChEBI ontology
in scheme: merged
source domain: bio
source schema: bio_entities

ChemicalRole
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Chemical Role
status: STANDARD
subclass of: RolesSchemaEnum
definition: Roles played by molecular entities within a chemical context, dynamically populated from ChEBI. Includes roles such as catalyst, reagent, solvent, indicator, buffer, and other chemical functions.
in scheme: merged
publishers: https://www.ebi.ac.uk/chebi
source domain: chemistry
source schema: roles
stewards: https://www.ebi.ac.uk/chebi

ClinicalFinding
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Clinical Finding
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Clinical findings and observations
in scheme: merged
source domain: bio
source schema: bio_entities

Disease
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Human diseases from the Mondo Disease Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

Drug
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Pharmaceutical drugs and medications
in scheme: merged
source domain: bio
source schema: bio_entities

Environment
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Environmental systems and biomes
in scheme: merged
source domain: bio
source schema: bio_entities

EnvironmentalMaterial
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Environmental Material
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Environmental materials and substances
in scheme: merged
source domain: bio
source schema: bio_entities

EvidenceType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Evidence Type
status: STANDARD
subclass of: EvidenceSchemaEnum
definition: Types of evidence used to support assertions, dynamically populated from the Evidence and Conclusion Ontology (ECO). Includes experimental evidence, computational evidence, author statements, and other evidence types.
in scheme: merged
publishers: https://evidenceontology.org
source domain: provenance
source schema: evidence
stewards: https://evidenceontology.org

GeneFeature
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Gene Feature
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Gene-related sequence features
in scheme: merged
source domain: bio
source schema: bio_entities

GeneticDisease
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Genetic Disease
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Hereditary and genetic diseases
in scheme: merged
source domain: bio
source schema: bio_entities

HumanAnatomicalStructure
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Human Anatomical Structure
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Anatomical structures specific to humans (Homo sapiens)
in scheme: merged
source domain: bio
source schema: bio_entities

ImmuneCell
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Immune Cell
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Immune system cell types (leukocytes and their subtypes)
in scheme: merged
source domain: bio
source schema: bio_entities

InfectiousDisease
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Infectious Disease
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Infectious diseases caused by pathogenic organisms
in scheme: merged
source domain: bio
source schema: bio_entities

InvestigativeProtocolEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Investigative Protocol
status: DRAFT
subclass of: InvestigationSchemaEnum
definition: Enum: InvestigativeProtocolEnum
in scheme: merged
source domain: root
source schema: investigation

MetabolicProcess
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Metabolic Process
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Metabolic processes and pathways
in scheme: merged
source domain: bio
source schema: bio_entities

Metabolite
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Metabolites and metabolic intermediates
in scheme: merged
source domain: bio
source schema: bio_entities

MetazoanAnatomicalStructure
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Metazoan Anatomical Structure
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Any anatomical structure found in metazoan organisms, including organs, tissues, and body parts
in scheme: merged
source domain: bio
source schema: bio_entities

MolecularFunction
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Molecular Function
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Molecular functions from Gene Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

NeuronType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Neuron Type
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Neuron cell types from the Cell Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

OccupationEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Occupation
status: DRAFT
subclass of: DemographicsSchemaEnum
definition: The principal activity that a person does to earn money. Dynamic enum populated from NCIT occupation hierarchy including medical, professional, service, and military occupations.
in scheme: merged
source domain: root
source schema: demographics

OrganismTaxonEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Organism Taxon
status: DRAFT
subclass of: TaxonomySchemaEnum
definition: Enum: OrganismTaxonEnum
in scheme: merged
source domain: bio
source schema: taxonomy

Phenotype
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Phenotypic abnormalities from Human Phenotype Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

PhysicalQuality
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Physical Quality
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Physical qualities like size, shape, color
in scheme: merged
source domain: bio
source schema: bio_entities

PlantAnatomicalStructure
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Plant Anatomical Structure
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Any anatomical structure found in plant organisms
in scheme: merged
source domain: bio
source schema: bio_entities

PlantExposureEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Plant Exposure
status: DRAFT
subclass of: PlantExperimentalConditionsSchemaEnum
definition: A plant experimental condition describing the application of an abiotic (chemical, physical) or biotic (pathogen, insect, plant) exposure. Dynamically populated from PECO.
in scheme: merged
source domain: bio
source schema: plant_experimental_conditions

Protein
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Proteins and protein complexes
in scheme: merged
source domain: bio
source schema: bio_entities

Quality
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Phenotypic qualities and attributes from PATO
in scheme: merged
source domain: bio
source schema: bio_entities

RadiationTypeEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Radiation Type
status: DRAFT
subclass of: RadiationSchemaEnum
definition: High-level classification of radiation types including electromagnetic, acoustic, and particle radiation. Dynamically populated from ENVO.
in scheme: merged
source domain: physics
source schema: radiation

SampleProcessingEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Sample Processing
status: DRAFT
subclass of: InvestigationSchemaEnum
definition: Enum: SampleProcessingEnum
in scheme: merged
source domain: root
source schema: investigation

SequenceFeature
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Sequence Feature
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Sequence features from the Sequence Ontology
in scheme: merged
source domain: bio
source schema: bio_entities

StemCell
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Stem Cell
status: DRAFT
subclass of: BioEntitiesSchemaEnum
definition: Stem cell types and progenitor cells
in scheme: merged
source domain: bio
source schema: bio_entities

StudyDesignEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Study Design
status: DRAFT
subclass of: InvestigationSchemaEnum
definition: Enum: StudyDesignEnum
in scheme: merged
source domain: root
source schema: investigation

StudyTypeEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Study Type
status: DRAFT
subclass of: InvestigationSchemaEnum
definition: Types of studies, including clinical trials, observational studies, and other research investigations. Dynamically populated from NCIT descendants of Study (NCIT:C63536).
in scheme: merged
source domain: root
source schema: investigation

valuesets_merged_hierarchy
type: Ontology
license: MIT
title: Merged Value Sets with Hierarchical Structure
definition: All value sets merged into a single hierarchical structure with is_a relationships

AnalyticalChemistryDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for analytical_chemistry value sets
in scheme: merged

ArxivCategoriesSchemaEnum
type: Class
subclass of: PublishingDomainEnum
definition: Schema-level enum for arxiv_categories in publishing
in scheme: merged
source file: publishing/arxiv_categories.yaml

BgcCategoriesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for bgc_categories in bio
in scheme: merged
source file: bio/bgc_categories.yaml

BiosafetySchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for biosafety in bio
in scheme: merged
source file: bio/biosafety.yaml

CollectionMethodsSchemaEnum
type: Class
subclass of: EarthScienceDomainEnum
definition: Schema-level enum for collection_methods in earth_science
in scheme: merged
source file: earth_science/collection_methods.yaml

ContributorRolesSchemaEnum
type: Class
subclass of: DataCatalogDomainEnum
definition: Schema-level enum for contributor_roles in data_catalog
in scheme: merged
source file: data_catalog/contributor_roles.yaml

ContributorSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for contributor in root
in scheme: merged
source file: contributor.yaml

CurrencyChemicalsSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for currency_chemicals in bio
in scheme: merged
source file: bio/currency_chemicals.yaml

DataAbsentReasonSchemaEnum
type: Class
subclass of: DataDomainEnum
definition: Schema-level enum for data_absent_reason in data
in scheme: merged
source file: data/data_absent_reason.yaml

DiagnosisCategoriesSchemaEnum
type: Class
subclass of: MedicalDomainEnum
definition: Schema-level enum for diagnosis_categories in medical
in scheme: merged
source file: medical/pediatric_oncology/diagnosis_categories.yaml

EcologicalInteractionsSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for ecological_interactions in root
in scheme: merged
source file: ecological_interactions.yaml

EvidenceSchemaEnum
type: Class
subclass of: ProvenanceDomainEnum
definition: Schema-level enum for evidence in provenance
in scheme: merged
source file: provenance/evidence.yaml

ExpressionUnitsSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for expression_units in bio
in scheme: merged
source file: bio/expression_units.yaml

FaoSoilSchemaEnum
type: Class
subclass of: EarthScienceDomainEnum
definition: Schema-level enum for fao_soil in earth_science
in scheme: merged
source file: earth_science/fao_soil.yaml

FixitySchemaEnum
type: Class
subclass of: PreservationDomainEnum
definition: Schema-level enum for fixity in preservation
in scheme: merged
source file: preservation/fixity.yaml

FossilFuelsSchemaEnum
type: Class
subclass of: EnergyDomainEnum
definition: Schema-level enum for fossil_fuels in energy
in scheme: merged
source file: energy/fossil_fuels.yaml

GeneticsSchemaEnum
type: Class
subclass of: ClinicalDomainEnum
definition: Schema-level enum for genetics in clinical
in scheme: merged
source file: clinical/genetics.yaml

GenomeFeaturesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for genome_features in bio
in scheme: merged
source file: bio/genome_features.yaml

GeographyDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for geography value sets
in scheme: merged

GoAspectSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for go_aspect in bio
in scheme: merged
source file: bio/go_aspect.yaml

GoCausalitySchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for go_causality in bio
in scheme: merged
source file: bio/go_causality.yaml

HealthDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for health value sets
in scheme: merged

HealthSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for health in root
in scheme: merged
source file: health.yaml

HealthcareSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for healthcare in root
in scheme: merged
source file: healthcare.yaml

InsdcGeographicLocationsSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for insdc_geographic_locations in bio
in scheme: merged
source file: bio/insdc_geographic_locations.yaml

InsdcMissingValuesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for insdc_missing_values in bio
in scheme: merged
source file: bio/insdc_missing_values.yaml

LipidCategoriesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for lipid_categories in bio
in scheme: merged
source file: bio/lipid_categories.yaml

OntologiesSchemaEnum
type: Class
subclass of: ComputingDomainEnum
definition: Schema-level enum for ontologies in computing
in scheme: merged
source file: computing/ontologies.yaml

PersonStatusSchemaEnum
type: Class
subclass of: SocialDomainEnum
definition: Schema-level enum for person_status in social
in scheme: merged
source file: social/person_status.yaml

PhysiographicFeaturesSchemaEnum
type: Class
subclass of: EarthScienceDomainEnum
definition: Schema-level enum for physiographic_features in earth_science
in scheme: merged
source file: earth_science/physiographic_features.yaml

PlantBiologySchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for plant_biology in bio
in scheme: merged
source file: bio/plant_biology.yaml

PlantDevelopmentalStagesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for plant_developmental_stages in bio
in scheme: merged
source file: bio/plant_developmental_stages.yaml

PlantSexSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for plant_sex in bio
in scheme: merged
source file: bio/plant_sex.yaml

PredictionOutcomesSchemaEnum
type: Class
subclass of: StatisticsDomainEnum
definition: Schema-level enum for prediction_outcomes in statistics
in scheme: merged
source file: statistics/prediction_outcomes.yaml

ProvenanceDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for provenance value sets
in scheme: merged

QuantityKindsSchemaEnum
type: Class
subclass of: UnitsDomainEnum
definition: Schema-level enum for quantity_kinds in units
in scheme: merged
source file: units/quantity_kinds.yaml

ReactionDirectionalitySchemaEnum
type: Class
subclass of: ChemistryDomainEnum
definition: Schema-level enum for reaction_directionality in chemistry
in scheme: merged
source file: chemistry/reaction_directionality.yaml

RelationsSchemaEnum
type: Class
subclass of: DataCatalogDomainEnum
definition: Schema-level enum for relations in data_catalog
in scheme: merged
source file: data_catalog/relations.yaml

RelationshipToOxygenSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for relationship_to_oxygen in bio
in scheme: merged
source file: bio/relationship_to_oxygen.yaml

ResourceTypesSchemaEnum
type: Class
subclass of: DataCatalogDomainEnum
definition: Schema-level enum for resource_types in data_catalog
in scheme: merged
source file: data_catalog/resource_types.yaml

SampleTypesSchemaEnum
type: Class
subclass of: EarthScienceDomainEnum
definition: Schema-level enum for sample_types in earth_science
in scheme: merged
source file: earth_science/sample_types.yaml

SpatialDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for spatial value sets
in scheme: merged

StatesOfMatterSchemaEnum
type: Class
subclass of: PhysicsDomainEnum
definition: Schema-level enum for states_of_matter in physics
in scheme: merged
source file: physics/states_of_matter.yaml

StatisticsDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for statistics value sets
in scheme: merged

StatisticsSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for statistics in root
in scheme: merged
source file: statistics.yaml

StewardshipSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for stewardship in root
in scheme: merged
source file: stewardship.yaml

TimeDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for time value sets
in scheme: merged

TrophicLevelsSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for trophic_levels in bio
in scheme: merged
source file: bio/trophic_levels.yaml

UniprotSpeciesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for uniprot_species in bio
in scheme: merged
source file: bio/uniprot_species.yaml

ViralGenomeTypesSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for viral_genome_types in bio
in scheme: merged
source file: bio/viral_genome_types.yaml

VisualDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for visual value sets
in scheme: merged

IMAGE
type: Class
subclass of: MLModalityType
definition: Visual image data
examples: photographs, diagrams, scans

PDB
type: Class
subclass of: FileFormat
definition: Protein Data Bank coordinate format
applications: atomic coordinates, legacy format
extension: .pdb

MMCIF
type: Class
subclass of: FileFormat
definition: Macromolecular Crystallographic Information File
applications: atomic coordinates, modern PDB format
extension: .cif

FASTA
type: Class
subclass of: SequenceFileFormat
definition: FASTA sequence format
content: sequences only
extensions: .fa, .fasta, .fna, .ffn, .faa, .frn

FASTQ
type: Class
subclass of: SequenceFileFormat
definition: FASTQ sequence with quality format
content: sequences and quality scores
extensions: .fq, .fastq

TXT
type: Class
subclass of: DocumentFormatEnum
alternative label: plain text format (unformatted)
definition: Plain text file
encoding: UTF-8, ASCII
extension: .txt
mime type: text/plain

HTML
type: Class
subclass of: DocumentFormatEnum
definition: HyperText Markup Language
extension: .html, .htm
mime type: text/html

XML
type: Class
subclass of: DocumentFormatEnum
definition: Extensible Markup Language
extension: .xml
mime type: application/xml

BAM
type: Class
subclass of: SequenceFileFormat
definition: Binary Alignment Map format
content: aligned sequences (binary)
extensions: .bam

SAM
type: Class
subclass of: SequenceFileFormat
definition: Sequence Alignment Map format
content: aligned sequences (text)
extensions: .sam

VCF
type: Class
subclass of: SequenceFileFormat
definition: Variant Call Format
content: genetic variants
extensions: .vcf

BCF
type: Class
subclass of: SequenceFileFormat
definition: Binary Variant Call Format
content: genetic variants (binary)
extensions: .bcf

SFF
type: Class
subclass of: SequenceFileFormat
definition: Standard Flowgram Format (454)
content: 454 sequencing data
extensions: .sff
status: legacy

GIF
type: Class
subclass of: ImageFileFormatEnum
definition: Graphics Interchange Format
extension: .gif
features: animation support
mime type: image/gif

TSV
type: Class
subclass of: DataFormatEnum
definition: Tab-Separated Values
delimiter: tab
extension: .tsv, .tab
mime type: text/tab-separated-values

PDF
type: Class
subclass of: DocumentFormatEnum
definition: Portable Document Format
creator: Adobe
extension: .pdf
mime type: application/pdf

BMP
type: Class
subclass of: ImageFileFormatEnum
definition: Bitmap Image File
compression: uncompressed
extension: .bmp
mime type: image/bmp

SVG
type: Class
subclass of: ImageFileFormatEnum
definition: Scalable Vector Graphics
extension: .svg
mime type: image/svg+xml
type: vector

YAML
type: Class
subclass of: DataFormatEnum
definition: YAML Ain't Markup Language
extension: .yaml, .yml
mime type: application/x-yaml

LATEX
type: Class
subclass of: DocumentFormatEnum
alternative label: LaTeX
alternative label: latex
definition: LaTeX document
extension: .tex
mime type: application/x-latex
use: scientific documents

GZIP
type: Class
title: GZIP format
subclass of: CompressionFormat
definition: GNU zip compression format
mime type: application/gzip
typical extension: .gz

VIDEO_AVI
type: Class
title: AVI
subclass of: MLMediaType
definition: Audio Video Interleaved format
mime type: video/x-msvideo
modality: video

TRANSCRIPTOME_SEQUENCING
type: Class
subclass of: SequencingApplication
alternative label: RNA-Seq
definition: RNA sequencing (RNA-seq)

CHROMATIN_IMMUNOPRECIPITATION
type: Class
subclass of: SequencingApplication
alternative label: Immunoprecipitation experiment
definition: ChIP-seq

WHOLE_GENOME_SEQUENCING
type: Class
subclass of: SequencingApplication
definition: Whole genome sequencing (WGS)

WHOLE_EXOME_SEQUENCING
type: Class
subclass of: SequencingApplication
alternative label: Exome sequencing
definition: Whole exome sequencing (WES)

METAGENOMICS
type: Class
subclass of: SequencingApplication
alternative label: Metagenomic sequencing
definition: Metagenomic sequencing

SINGLE_CELL_TRANSCRIPTOMICS
type: Class
subclass of: SequencingApplication
alternative label: Single-cell sequencing
definition: Single-cell transcriptomics

ANDORRA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Andorra

AFGHANISTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Afghanistan

ANTIGUA_AND_BARBUDA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Antigua and Barbuda

ANGUILLA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Anguilla

ALBANIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Albania

ARMENIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Armenia

ANGOLA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Angola

ANTARCTICA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Antarctica

AMERICAN_SAMOA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: American Samoa

ARUBA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Aruba

AZERBAIJAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Azerbaijan

BOSNIA_AND_HERZEGOVINA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bosnia and Herzegovina

BARBADOS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Barbados

BURKINA_FASO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Burkina Faso

BULGARIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bulgaria

BAHRAIN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bahrain

BURUNDI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Burundi

BENIN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Benin

SAINT_BARTHELEMY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Barthelemy

BERMUDA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bermuda

BRUNEI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Brunei

BOLIVIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bolivia

BAHAMAS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bahamas

BHUTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bhutan

BOUVET_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bouvet Island

BOTSWANA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Botswana

BELARUS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Belarus

BELIZE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Belize

COCOS_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cocos Islands

DEMOCRATIC_REPUBLIC_OF_THE_CONGO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Democratic Republic of the Congo

CENTRAL_AFRICAN_REPUBLIC
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Central African Republic

REPUBLIC_OF_THE_CONGO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Republic of the Congo

COTE_DIVOIRE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cote d'Ivoire

COOK_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cook Islands

CAMEROON
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cameroon

COSTA_RICA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Costa Rica

CUBA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cuba

CAPE_VERDE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cape Verde

CURACAO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Curacao

CHRISTMAS_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Christmas Island

CYPRUS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cyprus

CZECHIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Czechia

DJIBOUTI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Djibouti

DOMINICA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Dominica

DOMINICAN_REPUBLIC
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Dominican Republic

ALGERIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Algeria

ECUADOR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Ecuador

ESTONIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Estonia

WESTERN_SAHARA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Western Sahara

ERITREA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Eritrea

ETHIOPIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Ethiopia

FIJI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Fiji

FALKLAND_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Falkland Islands (Islas Malvinas)

MICRONESIA_FEDERATED_STATES_OF
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Micronesia, Federated States of

FAROE_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Faroe Islands

GABON
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Gabon

GRENADA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Grenada

GEORGIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Georgia

FRENCH_GUIANA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: French Guiana

GUERNSEY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guernsey

GHANA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Ghana

GIBRALTAR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Gibraltar

GREENLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Greenland

GAMBIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Gambia

GUINEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guinea

GUADELOUPE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guadeloupe

EQUATORIAL_GUINEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Equatorial Guinea

SOUTH_GEORGIA_AND_THE_SOUTH_SANDWICH_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: South Georgia and the South Sandwich Islands

GUATEMALA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guatemala

GUAM
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guam

GUINEA_BISSAU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guinea-Bissau

GUYANA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Guyana

HONG_KONG
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Hong Kong

HEARD_ISLAND_AND_MCDONALD_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Heard Island and McDonald Islands

HONDURAS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Honduras

CROATIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Croatia

HAITI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Haiti

HUNGARY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Hungary

ISLE_OF_MAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Isle of Man

IRAQ
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Iraq

IRAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Iran

ICELAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Iceland

JERSEY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Jersey

JAMAICA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Jamaica

JORDAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Jordan

KYRGYZSTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kyrgyzstan

CAMBODIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cambodia

KIRIBATI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kiribati

COMOROS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Comoros

SAINT_KITTS_AND_NEVIS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Kitts and Nevis

NORTH_KOREA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: North Korea

KUWAIT
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kuwait

CAYMAN_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Cayman Islands

KAZAKHSTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kazakhstan

LAOS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Laos

LEBANON
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Lebanon

SAINT_LUCIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Lucia

LIECHTENSTEIN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Liechtenstein

SRI_LANKA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Sri Lanka

LIBERIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Liberia

LESOTHO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Lesotho

LITHUANIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Lithuania

LUXEMBOURG
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Luxembourg

LATVIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Latvia

LIBYA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Libya

MOROCCO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Morocco

MONACO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Monaco

MOLDOVA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Moldova

MONTENEGRO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Montenegro

SAINT_MARTIN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Martin

MADAGASCAR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Madagascar

MARSHALL_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Marshall Islands

NORTH_MACEDONIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: North Macedonia

MALI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mali

MYANMAR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Myanmar

MONGOLIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mongolia

MACAU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Macau

NORTHERN_MARIANA_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Northern Mariana Islands

MARTINIQUE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Martinique

MAURITANIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mauritania

MONTSERRAT
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Montserrat

MALTA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Malta

MAURITIUS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mauritius

MALDIVES
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Maldives

MALAWI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Malawi

MOZAMBIQUE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mozambique

NAMIBIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Namibia

NEW_CALEDONIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: New Caledonia

NIGER
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Niger

NORFOLK_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Norfolk Island

NICARAGUA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Nicaragua

NEPAL
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Nepal

NAURU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Nauru

NIUE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Niue

OMAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Oman

PANAMA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Panama

FRENCH_POLYNESIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: French Polynesia

PAPUA_NEW_GUINEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Papua New Guinea

SAINT_PIERRE_AND_MIQUELON
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Pierre and Miquelon

PITCAIRN_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Pitcairn Islands

PUERTO_RICO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Puerto Rico

STATE_OF_PALESTINE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: State of Palestine

PALAU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Palau

PARAGUAY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Paraguay

QATAR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Qatar

REUNION
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Reunion

ROMANIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Romania

SERBIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Serbia

RWANDA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Rwanda

SOLOMON_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Solomon Islands

SEYCHELLES
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Seychelles

SUDAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Sudan

SAINT_HELENA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Helena

SLOVENIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Slovenia

SLOVAKIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Slovakia

SIERRA_LEONE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Sierra Leone

SAN_MARINO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: San Marino

SENEGAL
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Senegal

SOMALIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Somalia

SURINAME
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Suriname

SOUTH_SUDAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: South Sudan

SAO_TOME_AND_PRINCIPE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Sao Tome and Principe

EL_SALVADOR
type: Class
subclass of: InsdcGeographicLocationEnum
definition: El Salvador

SINT_MAARTEN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Sint Maarten

SYRIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Syria

ESWATINI
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Eswatini

TURKS_AND_CAICOS_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Turks and Caicos Islands

CHAD
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Chad

FRENCH_SOUTHERN_AND_ANTARCTIC_LANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: French Southern and Antarctic Lands

TOGO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Togo

TAJIKISTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tajikistan

TOKELAU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tokelau

TIMOR_LESTE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Timor-Leste

TURKMENISTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Turkmenistan

TUNISIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tunisia

TONGA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tonga

TRINIDAD_AND_TOBAGO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Trinidad and Tobago

TUVALU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tuvalu

TAIWAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Taiwan

TANZANIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tanzania

UGANDA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Uganda

URUGUAY
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Uruguay

UZBEKISTAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Uzbekistan

SAINT_VINCENT_AND_THE_GRENADINES
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Saint Vincent and the Grenadines

BRITISH_VIRGIN_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: British Virgin Islands

VIRGIN_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Virgin Islands

VANUATU
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Vanuatu

WALLIS_AND_FUTUNA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Wallis and Futuna

SAMOA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Samoa

KOSOVO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kosovo
note: Provisional ISO 3166 code

YEMEN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Yemen

MAYOTTE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mayotte

ZAMBIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Zambia

ZIMBABWE
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Zimbabwe

COPYRIGHTED
type: Class
subclass of: CopyrightStatus
definition: The object is protected by copyright.

PUBLIC_DOMAIN
type: Class
title: Public Domain
subclass of: CopyrightStatus
definition: The object is not protected by copyright, either because copyright has expired, was never applicable, or has been waived.

UNKNOWN
type: Class
subclass of: CopyrightStatus
definition: The copyright status cannot be determined.

ADLER_32
type: Class
title: Adler-32
subclass of: CryptographicHashFunction
definition: A checksum algorithm developed by Mark Adler. Faster than CRC32 but with weaker error detection. Used in zlib compression.
output bits: 32
security level: non-cryptographic

CRC32
type: Class
subclass of: CryptographicHashFunction
definition: Cyclic Redundancy Check with 32-bit output. Used for error detection in network transmissions and storage. Not cryptographically secure.
output bits: 32
security level: non-cryptographic

HAVAL
type: Class
subclass of: CryptographicHashFunction
definition: A cryptographic hash function that can produce hash values of 128, 160, 192, 224, or 256 bits. Variable number of rounds.
output bits: variable
security level: deprecated

MD2
type: Class
subclass of: CryptographicHashFunction
definition: Message Digest 2 algorithm producing a 128-bit hash value. Designed for 8-bit computers. Considered cryptographically broken.
output bits: 128
security level: broken

MD5
type: Class
subclass of: CryptographicHashFunction
definition: Message Digest 5 algorithm producing a 128-bit hash value. Widely used but vulnerable to collision attacks. Acceptable for non-security integrity checks only.
output bits: 128
security level: weak

SHA_1
type: Class
title: SHA-1
subclass of: CryptographicHashFunction
alternative label: SHA1
definition: Secure Hash Algorithm 1 producing a 160-bit hash value. Deprecated for security applications due to collision vulnerabilities. Still acceptable for integrity verification in some contexts.
output bits: 160
security level: weak

SHA_256
type: Class
title: SHA-256
subclass of: CryptographicHashFunction
alternative label: SHA256
definition: SHA-2 variant producing a 256-bit hash value. Widely used and considered secure for most applications. Recommended for digital preservation.
output bits: 256
security level: secure

SHA_384
type: Class
title: SHA-384
subclass of: CryptographicHashFunction
alternative label: SHA384
definition: SHA-2 variant producing a 384-bit hash value. Truncated version of SHA-512.
output bits: 384
security level: secure

SHA_512
type: Class
title: SHA-512
subclass of: CryptographicHashFunction
alternative label: SHA512
definition: SHA-2 variant producing a 512-bit hash value. Highest security level in the SHA-2 family.
output bits: 512
security level: secure

TIGER
type: Class
title: Tiger
subclass of: CryptographicHashFunction
definition: A cryptographic hash function designed for 64-bit platforms. Produces a 192-bit hash value.
output bits: 192
security level: adequate

UNKNOWN
type: Class
subclass of: CryptographicHashFunction
definition: The hash algorithm is not known or not specified.

WHIRLPOOL
type: Class
title: Whirlpool
subclass of: CryptographicHashFunction
definition: A cryptographic hash function producing a 512-bit hash value. Based on a modified AES block cipher.
output bits: 512
security level: secure

FAILURE
type: Class
subclass of: PreservationEventOutcome
definition: The event failed to complete.

SUCCESS
type: Class
subclass of: PreservationEventOutcome
definition: The event completed successfully.

WARNING
type: Class
subclass of: PreservationEventOutcome
definition: The event completed with warnings or issues.

ACCESSION
type: Class
subclass of: PreservationEventType
definition: The process of adding objects to a repository's holdings.

APPRAISAL
type: Class
subclass of: PreservationEventType
definition: The process of evaluating objects for long-term retention.

CAPTURE
type: Class
subclass of: PreservationEventType
definition: The process of recording or acquiring digital content.

COMPRESSION
type: Class
subclass of: PreservationEventType
definition: The process of reducing file size through encoding.

COMPILING
type: Class
subclass of: PreservationEventType
definition: The process of converting source code into executable code.

CREATION
type: Class
subclass of: PreservationEventType
definition: The act of creating a new digital object.

DEACCESSION
type: Class
subclass of: PreservationEventType
definition: The process of removing objects from a repository's holdings.

DECOMPRESSION
type: Class
subclass of: PreservationEventType
definition: The process of restoring compressed data to its original form.

DELETION
type: Class
subclass of: PreservationEventType
definition: The act of removing a digital object.

DECRYPTION
type: Class
subclass of: PreservationEventType
definition: The process of converting encrypted data back to plaintext.

DIGITAL_SIGNATURE_GENERATION
type: Class
title: Digital Signature Generation
subclass of: PreservationEventType
definition: The process of creating a digital signature for authentication.

DISPLAYING
type: Class
subclass of: PreservationEventType
definition: The process of presenting content for viewing.

DISSEMINATION
type: Class
subclass of: PreservationEventType
definition: The process of making content available to users.

DIGITAL_SIGNATURE_VALIDATION
type: Class
title: Digital Signature Validation
subclass of: PreservationEventType
definition: The process of verifying the authenticity of a digital signature.

ENCRYPTION
type: Class
subclass of: PreservationEventType
definition: The process of converting plaintext to ciphertext.

EXECUTION
type: Class
subclass of: PreservationEventType
definition: The process of running software or scripts.

EXPORTING
type: Class
subclass of: PreservationEventType
definition: The process of extracting content from a system.

EXTRACTION
type: Class
subclass of: PreservationEventType
definition: The process of retrieving content from a container or archive.

FILENAME_CHANGE
type: Class
title: Filename Change
subclass of: PreservationEventType
definition: The act of modifying a file's name.

FIXITY_CHECK
type: Class
title: Fixity Check
subclass of: PreservationEventType
definition: The process of verifying data integrity using checksums or hashes.

FORMAT_IDENTIFICATION
type: Class
title: Format Identification
subclass of: PreservationEventType
definition: The process of determining the file format of a digital object.

FORENSIC_FEATURE_ANALYSIS
type: Class
title: Forensic Feature Analysis
subclass of: PreservationEventType
definition: Analysis of digital objects for authenticity or provenance evidence.

IMAGING
type: Class
subclass of: PreservationEventType
definition: The process of creating a bit-level copy of storage media.

INGESTION_END
type: Class
title: Ingestion End
subclass of: PreservationEventType
definition: The completion of the ingestion process.

INGESTION
type: Class
subclass of: PreservationEventType
definition: The process of accepting and processing submitted content.

INGESTION_START
type: Class
title: Ingestion Start
subclass of: PreservationEventType
definition: The beginning of the ingestion process.

INTERPRETING
type: Class
subclass of: PreservationEventType
definition: The process of rendering or executing interpretable content.

INFORMATION_PACKAGE_CREATION
type: Class
title: Information Package Creation
subclass of: PreservationEventType
definition: Creating a packaged unit of content and metadata (SIP, AIP, DIP).

INFORMATION_PACKAGE_MERGING
type: Class
title: Information Package Merging
subclass of: PreservationEventType
definition: Combining multiple information packages into one.

INFORMATION_PACKAGE_SPLITTING
type: Class
title: Information Package Splitting
subclass of: PreservationEventType
definition: Dividing an information package into multiple packages.

METADATA_EXTRACTION
type: Class
title: Metadata Extraction
subclass of: PreservationEventType
definition: The process of extracting metadata from digital objects.

METADATA_MODIFICATION
type: Class
title: Metadata Modification
subclass of: PreservationEventType
definition: The process of changing metadata associated with an object.

MESSAGE_DIGEST_CALCULATION
type: Class
title: Message Digest Calculation
subclass of: PreservationEventType
definition: The process of computing a hash or checksum value.

MIGRATION
type: Class
subclass of: PreservationEventType
definition: The process of converting content from one format to another to ensure continued accessibility.

MODIFICATION
type: Class
subclass of: PreservationEventType
definition: The act of changing the content of a digital object.

NORMALIZATION
type: Class
subclass of: PreservationEventType
definition: The process of converting content to a standard format for preservation or access.

PACKING
type: Class
subclass of: PreservationEventType
definition: The process of combining files into a container format.

POLICY_ASSIGNMENT
type: Class
title: Policy Assignment
subclass of: PreservationEventType
definition: The act of associating preservation policies with objects.

PRINTING
type: Class
subclass of: PreservationEventType
definition: The process of producing a physical copy of digital content.

QUARANTINE
type: Class
subclass of: PreservationEventType
definition: Isolating objects suspected of containing malware or corruption.

RECOVERY
type: Class
subclass of: PreservationEventType
definition: The process of restoring objects from backup or damaged media.

REDACTION
type: Class
subclass of: PreservationEventType
definition: The process of removing sensitive content from objects.

REFRESHMENT
type: Class
subclass of: PreservationEventType
definition: Copying data to new storage media without format change.

RENDERING
type: Class
subclass of: PreservationEventType
definition: The process of generating a viewable representation.

REPLICATION
type: Class
subclass of: PreservationEventType
definition: Creating exact copies for redundancy or distribution.

TRANSFER
type: Class
subclass of: PreservationEventType
definition: Moving objects between systems or locations.

UNPACKING
type: Class
subclass of: PreservationEventType
definition: Extracting files from a container format.

UNQUARANTINE
type: Class
subclass of: PreservationEventType
definition: Releasing objects from quarantine after verification.

VALIDATION
type: Class
subclass of: PreservationEventType
definition: Verifying that objects conform to expected specifications.

VIRUS_CHECK
type: Class
title: Virus Check
subclass of: PreservationEventType
definition: Scanning objects for malware or viruses.

BITSTREAM
type: Class
subclass of: DigitalObjectCategory
definition: Contiguous or non-contiguous data within a file that has meaningful properties for preservation purposes. A bitstream cannot be transformed into a standalone file without the addition of file structure.

FILE
type: Class
subclass of: DigitalObjectCategory
definition: A named and ordered sequence of bytes that is known to an operating system. A file can be zero or more bytes and has a file format, access permissions, and other file system characteristics.

INTELLECTUAL_ENTITY
type: Class
title: Intellectual Entity
subclass of: DigitalObjectCategory
definition: A coherent set of content that is reasonably described as a unit. Examples include a book, a photograph, a database, or a software application. An intellectual entity may contain other intellectual entities.

REPRESENTATION
type: Class
subclass of: DigitalObjectCategory
definition: The set of files, including structural metadata, needed for a complete and reasonable rendition of an intellectual entity. A digital object may have multiple representations.

CAPABILITY
type: Class
subclass of: PreservationLevelRole
definition: The preservation level that the repository is capable of providing based on its technical infrastructure and resources.

INTENTION
type: Class
subclass of: PreservationLevelRole
definition: The preservation level that the repository intends to provide for the object, based on policy decisions.

REQUIREMENT
type: Class
subclass of: PreservationLevelRole
definition: The preservation level required by the depositor or other stakeholder for the object.

COPYRIGHT
type: Class
subclass of: RightsBasis
definition: Rights based on copyright law.

INSTITUTIONAL_POLICY
type: Class
title: Institutional Policy
subclass of: RightsBasis
definition: Rights based on the policies of the holding institution.

LICENSE
type: Class
subclass of: RightsBasis
definition: Rights based on a license agreement.

OTHER
type: Class
subclass of: RightsBasis
definition: Rights based on another basis not listed.

STATUTE
type: Class
subclass of: RightsBasis
definition: Rights based on statutory law other than copyright.

INTIMATE_PARTNER_VIOLENCE
type: Class
subclass of: GravitySdohDomainEnum
alternative label: IPV
alternative label: Intimate Partner Violence
alternative label: domestic violence
definition: Abuse occurring between people in a close relationship

PERFUSION_WEIGHTED
type: Class
title: Perfusion-weighted contrast
subclass of: MRIContrastTypeEnum
definition: Image contrast based on blood flow dynamics
measurement: cerebral blood flow/volume
typical use: stroke, tumor vascularity

ADOLESCENT
type: Class
subclass of: HumanAgeGroupEnum
alternative label: Adolescent
alternative label: Teenager
definition: A person 13 to 18 years of age
age range: 13-18 years

ADULT
type: Class
subclass of: HumanAgeGroupEnum
alternative label: Adult
definition: A person having attained full growth or maturity. Adults are of 19 to 120 years of age
age range: 19-120 years

CHILD
type: Class
subclass of: HumanAgeGroupEnum
alternative label: Child
definition: A person 2 to 12 years of age
age range: 2-12 years

ELDER_ABUSE
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Elder Abuse
definition: Abuse, neglect, or exploitation of older adults

INFANT
type: Class
subclass of: HumanAgeGroupEnum
alternative label: Infant
definition: A child between 1 and 23 months of age
age range: 1-23 months

DWI
type: Class
title: Diffusion-weighted imaging
subclass of: MRIModalityEnum
definition: Imaging sensitive to water molecule diffusion
contrast mechanism: water diffusion
parameter: apparent diffusion coefficient
typical use: stroke detection, fiber tracking

HEALTH_LITERACY
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Health Literacy
definition: Ability to obtain, process, and understand health information

FLOW_BATTERY
type: Class
title: flow battery
subclass of: GridEnergyStorageType
definition: Rechargeable battery using liquid electrolytes stored in external tanks for scalable capacity

LITHIUM_ION_BATTERY
type: Class
title: lithium-ion battery
subclass of: GridEnergyStorageType
definition: Rechargeable battery using lithium ion intercalation in electrode materials

SODIUM_ION_BATTERY
type: Class
title: sodium-ion battery
subclass of: GridEnergyStorageType
definition: Rechargeable battery using sodium ion intercalation as a lower-cost alternative to lithium-ion

NON_PUBLIC
type: Class
title: Non-Public
subclass of: AccessRights
alternative label: Closed
alternative label: Private
definition: The resource is not publicly accessible. May include confidential, sensitive, or internal-use-only resources.

PUBLIC
type: Class
subclass of: AccessRights
alternative label: Open
alternative label: Unrestricted
definition: The resource is publicly accessible to everyone without restrictions.

RESTRICTED
type: Class
subclass of: AccessRights
alternative label: Limited Access
definition: The resource is available under certain conditions or to authorized users only. Access may require authentication, payment, or agreement to terms.

SOLID
type: Class
subclass of: StateOfMatterEnum
definition: A state of matter where particles are closely packed together with fixed positions

LIQUID
type: Class
subclass of: StateOfMatterEnum
definition: A nearly incompressible fluid that conforms to the shape of its container

GAS
type: Class
subclass of: StateOfMatterEnum
definition: A compressible fluid that expands to fill its container

PLASMA
type: Class
subclass of: StateOfMatterEnum
definition: An ionized gas with freely moving charged particles

TRICLINIC
type: Class
title: Triclinic
subclass of: CrystalSystemEnum
alternative label: anorthic
definition: Crystal system with no symmetry constraints (a≠b≠c, α≠β≠γ≠90°)

MONOCLINIC
type: Class
title: Monoclinic
subclass of: CrystalSystemEnum
definition: Crystal system with one twofold axis of symmetry (a≠b≠c, α=γ=90°≠β)

ORTHORHOMBIC
type: Class
title: Orthorhombic
subclass of: CrystalSystemEnum
alternative label: rhombic
definition: Crystal system with three mutually perpendicular axes (a≠b≠c, α=β=γ=90°)

TETRAGONAL
type: Class
title: Tetragonal
subclass of: CrystalSystemEnum
definition: Crystal system with one fourfold axis (a=b≠c, α=β=γ=90°)

CUBIC
type: Class
title: Cubic
subclass of: CrystalSystemEnum
alternative label: isometric
definition: Crystal system with four threefold axes (a=b=c, α=β=γ=90°)

TRIGONAL
type: Class
title: Trigonal
subclass of: CrystalSystemEnum
alternative label: rhombohedral
definition: Crystal system with one threefold axis (a=b=c, α=β=γ≠90°)

BIOFERTILIZER
type: Class
title: biofertilizer
subclass of: BioproductCategoryType
definition: Biological preparations containing living microorganisms that enhance plant nutrient availability

LEFT
type: Class
title: Left side of a bilaterally symmetric organism
subclass of: AnatomicalSide
alternative label: left side

DEEP
type: Class
title: Away from the surface
subclass of: AnatomicalSide
alternative label: deep side
aliases: internal, inner

SUPERFICIAL
type: Class
title: Near the surface
subclass of: AnatomicalSide
alternative label: superficial side
aliases: external, outer

RIGHT
type: Class
title: Right side of a bilaterally symmetric organism
subclass of: AnatomicalSide
alternative label: right side

PARASAGITTAL
type: Class
title: Sagittal plane parallel to midline
subclass of: AnatomicalPlane
alternative label: parasagittal plane
note: any sagittal plane not at midline

MIDSAGITTAL
type: Class
title: Sagittal plane through the midline
subclass of: AnatomicalPlane
alternative label: midsagittal plane
aliases: median plane
note: divides body into equal left and right halves

ANTERIOR_POSTERIOR
type: Class
title: Anterior-posterior axis (head-tail axis)
subclass of: AnatomicalAxis
alternative label: anterior-posterior axis
aliases: AP axis, rostrocaudal axis

DORSAL_VENTRAL
type: Class
title: Dorsal-ventral axis (back-belly axis)
subclass of: AnatomicalAxis
alternative label: dorsal-ventral axis
aliases: DV axis

LEFT_RIGHT
type: Class
title: Left-right axis (lateral axis)
subclass of: AnatomicalAxis
alternative label: left-right axis
aliases: LR axis, mediolateral axis

CORONAL
type: Class
title: Vertical plane dividing body into anterior and posterior
subclass of: AnatomicalPlane
alternative label: horizontal plane
aliases: frontal plane
orientation: perpendicular to sagittal plane

SUPERIOR
type: Class
title: Above or upper (in standard anatomical position)
subclass of: AnatomicalSide
alternative label: superior side
aliases: cranial (toward head), upper

APICAL_BASAL
type: Class
title: Apical-basal axis
subclass of: AnatomicalAxis
alternative label: apical-basal gradient
context: epithelial cells, plant structures

INFERIOR
type: Class
title: Below or lower (in standard anatomical position)
subclass of: AnatomicalSide
alternative label: inferior side
aliases: caudal (toward tail), lower

ANTERIOR
type: Class
title: Front/ventral side in most animals, toward the head
subclass of: AnatomicalSide
alternative label: anterior side
aliases: front, rostral, cranial (in head region)

POSTERIOR
type: Class
title: Back/dorsal side in most animals, toward the tail
subclass of: AnatomicalSide
alternative label: posterior side
aliases: back, caudal

APICAL
type: Class
title: At or toward the apex or tip
subclass of: AnatomicalSide
alternative label: apical side
context: cells, organs, organisms

BASAL
type: Class
title: At or toward the base
subclass of: AnatomicalSide
alternative label: basal side
context: cells, organs, organisms

CENTRAL
type: Class
title: At or near the center
subclass of: AnatomicalSide
alternative label: central side
aliases: middle

CONTRALATERAL
type: Class
title: On the opposite side
subclass of: AnatomicalSide
alternative label: contralateral side
context: relative to a reference point

PROXIMAL
type: Class
title: Closer to the point of attachment or origin
subclass of: AnatomicalSide
alternative label: proximal side
context: commonly used for limbs

DISTAL
type: Class
title: Further from the point of attachment or origin
subclass of: AnatomicalSide
alternative label: distal side
context: commonly used for limbs

DORSAL
type: Class
title: Back side of organism (top in humans when standing)
subclass of: AnatomicalSide
alternative label: dorsal side
aliases: back (in vertebrates), upper (in humans)

IPSILATERAL
type: Class
title: On the same side
subclass of: AnatomicalSide
alternative label: ipsilateral side
context: relative to a reference point

LATERAL
type: Class
title: Away from the midline
subclass of: AnatomicalSide
alternative label: lateral side
aliases: side, outer

MEDIAL
type: Class
title: Toward the midline
subclass of: AnatomicalSide
alternative label: medial side
aliases: inner, middle

VENTRAL
type: Class
title: Belly side of organism (front in humans when standing)
subclass of: AnatomicalSide
alternative label: ventral side
aliases: belly, front (in vertebrates), lower (in humans)

ANTERIOR_REGION
type: Class
title: Region in the anterior portion
subclass of: AnatomicalRegion
alternative label: anterior region

POSTERIOR_REGION
type: Class
title: Region in the posterior portion
subclass of: AnatomicalRegion
alternative label: posterior region

APICAL_REGION
type: Class
title: Region in the apical portion
subclass of: AnatomicalRegion
alternative label: apical region

BASAL_REGION
type: Class
title: Region in the basal portion
subclass of: AnatomicalRegion
alternative label: basal region

CENTRAL_REGION
type: Class
title: Region in the central portion
subclass of: AnatomicalRegion
alternative label: central region

PROXIMAL_REGION
type: Class
title: Region in the proximal portion
subclass of: AnatomicalRegion
alternative label: proximal region

DISTAL_REGION
type: Class
title: Region in the distal portion
subclass of: AnatomicalRegion
alternative label: distal region

DORSAL_REGION
type: Class
title: Region in the dorsal portion
subclass of: AnatomicalRegion
alternative label: dorsal region

LATERAL_REGION
type: Class
title: Region in the lateral portion
subclass of: AnatomicalRegion
alternative label: lateral region

MEDIAL_REGION
type: Class
title: Region in the medial portion
subclass of: AnatomicalRegion
alternative label: medial region

VENTRAL_REGION
type: Class
title: Region in the ventral portion
subclass of: AnatomicalRegion
alternative label: ventral region

ANTERIOR_TO
type: Class
title: In front of
subclass of: SpatialRelationship
alternative label: anterior to

DISTAL_TO
type: Class
title: Further from the origin than
subclass of: SpatialRelationship
alternative label: distal to

DORSAL_TO
type: Class
title: Above/on the back side of
subclass of: SpatialRelationship
alternative label: dorsal to

POSTERIOR_TO
type: Class
title: Behind
subclass of: SpatialRelationship
alternative label: posterior to

PROXIMAL_TO
type: Class
title: Closer to the origin than
subclass of: SpatialRelationship
alternative label: proximal to

VENTRAL_TO
type: Class
title: Below/on the belly side of
subclass of: SpatialRelationship
alternative label: ventral to

DEEP_TO
type: Class
title: Further from the surface than
subclass of: SpatialRelationship
alternative label: deep to

SUPERFICIAL_TO
type: Class
title: Closer to the surface than
subclass of: SpatialRelationship
alternative label: superficial to

LATERAL_TO
type: Class
title: To the side of
subclass of: SpatialRelationship
alternative label: lateral to

MEDIAL_TO
type: Class
title: Toward the midline from
subclass of: SpatialRelationship
alternative label: X medial to y if x is closer to the midsagittal plane than y.

PERIPHERAL_REGION
type: Class
title: Region in the peripheral portion
subclass of: AnatomicalRegion
alternative label: peripheral region

SAGITTAL
type: Class
title: Vertical plane dividing body into left and right
subclass of: AnatomicalPlane
alternative label: sagittal plane
orientation: parallel to the median plane

BARITE
type: Class
title: barium sulfate
subclass of: CriticalMineral
definition: Barite (BaSO4) - drilling and chemicals
applications: oil drilling, chemicals, radiation shielding
formula: BaSO4

COA
type: Class
title: CoA
subclass of: CurrencyChemical
alternative label: coenzyme A
definition: Coenzyme A - acyl group carrier in fatty acid metabolism

ACETYL_COA
type: Class
title: Acetyl-CoA
subclass of: CurrencyChemical
definition: Acetyl coenzyme A - central metabolic intermediate, links glycolysis to citric acid cycle

ATP
type: Class
subclass of: CurrencyChemical
definition: Adenosine triphosphate - primary energy currency molecule in cells

NAD_PLUS
type: Class
title: NAD+
subclass of: CurrencyChemical
definition: Nicotinamide adenine dinucleotide (oxidized) - electron acceptor in catabolism

GTP
type: Class
subclass of: CurrencyChemical
definition: Guanosine triphosphate - energy molecule, protein synthesis and signaling

AMP
type: Class
subclass of: CurrencyChemical
alternative label: adenosine 5'-monophosphate
definition: Adenosine monophosphate - nucleotide, product of ADP hydrolysis

DDT
type: Class
subclass of: EndocrineDisruptorEnum
definition: Dichlorodiphenyltrichloroethane and metabolites

ETHANOL
type: Class
title: Ethanol
subclass of: BiofuelType
alternative label: Bioethanol
alternative label: Fuel Ethanol
definition: Alcohol biofuel (C2H5OH) produced by fermentation of sugars or starches, or from cellulosic biomass.
chemical formula: C2H5OH

FAD
type: Class
subclass of: CurrencyChemical
definition: Flavin adenine dinucleotide (oxidized) - electron acceptor in oxidation reactions

TRICLOSAN
type: Class
subclass of: EndocrineDisruptorEnum
definition: Triclosan

NADPH
type: Class
subclass of: CurrencyChemical
definition: Nicotinamide adenine dinucleotide phosphate (reduced) - anabolic reducing agent

U
type: Class
title: Selenocysteine
subclass of: AminoAcidExtendedEnum
alternative label: L-selenocysteine
codon: UGA with SECIS element
special: 21st amino acid
three letter: Sec

SOYBEAN_OIL
type: Class
title: Soybean Oil
subclass of: BiomassFeedstockType
definition: Vegetable oil from soybean seeds, used for biodiesel.
category: oil_crop
lipid rich: true

BENZENE
type: Class
subclass of: AirPollutantEnum
definition: Benzene vapor

ADP
type: Class
subclass of: CurrencyChemical
definition: Adenosine diphosphate - product of ATP hydrolysis, energy acceptor

FORMALDEHYDE
type: Class
subclass of: AirPollutantEnum
definition: Formaldehyde gas

ALIZARIN_CRIMSON
type: Class
title: alizarin
subclass of: TraditionalPigmentEnum
definition: Alizarin crimson (synthetic)
chemical: C14H8O4
hex: E32636
organic: synthetic organic

NADH
type: Class
subclass of: CurrencyChemical
definition: Nicotinamide adenine dinucleotide (reduced) - electron donor, reducing agent

FLUORIDE
type: Class
subclass of: WaterContaminantEnum
definition: Fluoride levels

GLUCOSE
type: Class
subclass of: FeedstockTypeEnum
definition: Glucose/dextrose
carbon source: true
source: Corn, sugarcane

CARBON_MONOXIDE
type: Class
subclass of: AirPollutantEnum
definition: Carbon monoxide (CO)

GDP
type: Class
subclass of: CurrencyChemical
definition: Guanosine diphosphate - product of GTP hydrolysis

INOSINE
type: Class
subclass of: NucleotideModificationEnum
definition: Inosine
pairs with: A, C, U
symbol: I
type: RNA editing

GLYCEROL
type: Class
subclass of: FeedstockTypeEnum
definition: Glycerol
carbon source: true
source: Biodiesel byproduct

PSEUDOURIDINE
type: Class
subclass of: NucleotideModificationEnum
definition: Pseudouridine
function: RNA stability
symbol: Ψ
type: RNA modification

FADH2
type: Class
subclass of: CurrencyChemical
definition: Flavin adenine dinucleotide (reduced) - electron donor in electron transport chain

SUCROSE
type: Class
subclass of: FeedstockTypeEnum
definition: Sucrose
carbon source: true
source: Sugarcane, sugar beet

NADP_PLUS
type: Class
title: NADP+
subclass of: CurrencyChemical
definition: Nicotinamide adenine dinucleotide phosphate (oxidized) - electron acceptor

LIPID
type: Class
subclass of: LipidCategory
broad match: SLM_000389145
definition: Lipid

SACCHARIDE
type: Class
title: polysaccharide
subclass of: BgcCategoryEnum
definition: Saccharide/polysaccharide biosynthetic gene clusters
biosynthetic enzyme: Glycosyltransferases
definition: Carbohydrate polymers and oligomers
examples: Cellulose, chitin, bacterial capsular polysaccharides

IRON
type: Class
title: iron atom
subclass of: CommonMineral
definition: Iron (Fe)
atomic number: 26
symbol: Fe

HYDROGEN
type: Class
title: Hydrogen fuel
subclass of: EnergySource
alternative label: dihydrogen
broad match: Hydrogen
emission free: true
oeo label: hydrogen
renewable: depends

SULFUR_DIOXIDE
type: Class
subclass of: AirPollutantEnum
definition: Sulfur dioxide (SO2)

SEVEN_METHYL_G
type: Class
title: 7-methylguanosine
subclass of: NucleotideModificationEnum
definition: 7-methylguanosine
function: translation initiation
symbol: m7G
type: mRNA cap

O
type: Class
title: Pyrrolysine (22nd amino acid)
subclass of: AminoAcidExtendedEnum
alternative label: L-pyrrolysine
codon: UAG in certain archaea/bacteria
special: 22nd amino acid
three letter: Pyl

SIX_METHYL_A
type: Class
title: N(6)-methyladenosine
subclass of: NucleotideModificationEnum
definition: N6-methyladenosine
function: RNA stability, translation
symbol: m6A
type: RNA modification

ALKALI_METALS
type: Class
title: alkali metal atom
subclass of: ElementFamilyEnum
definition: Group 1 elements (except hydrogen)
elements: Li, Na, K, Rb, Cs, Fr
group: 1

ENZYME
type: Class
title: cofactor
subclass of: CatalystTypeEnum
definition: Biological catalyst
specificity: high
type: protein

DIHYDROURIDINE
type: Class
title: dihydrouridine
subclass of: NucleotideModificationEnum
definition: Dihydrouridine
symbol: D
type: tRNA modification

FATTY_ACYLS_AND_DERIVATIVES
type: Class
subclass of: LipidCategory
alternative label: fatty-acyl group
broad match: SLM_000390054
definition: Fatty acyls and derivatives

FUNGICIDE
type: Class
subclass of: PesticideTypeEnum
definition: Chemical used to kill fungi

HERBICIDE
type: Class
subclass of: PesticideTypeEnum
definition: Chemical used to kill unwanted plants

PROTON
type: Class
subclass of: SubatomicParticleEnum
definition: Positively charged nucleon
charge: +1
composition: uud
mass: 938.272 MeV/c²
spin: 1/2
type: baryon

INSECTICIDE
type: Class
subclass of: PesticideTypeEnum
definition: Chemical used to kill insects

SALT
type: Class
subclass of: CommonMineral
definition: Salt (NaCl)
aliases: halite, rock salt
formula: NaCl

PRENOL_LIPIDS
type: Class
subclass of: LipidCategory
alternative label: isoprenoid
definition: Prenol Lipids
narrow match: CHEBI_16019

LEAD
type: Class
title: lead atom
subclass of: CommonMineral
definition: Lead (Pb)
atomic number: 82
symbol: Pb

MAGNESIUM
type: Class
title: magnesium atom
subclass of: CriticalMineral
definition: Magnesium (Mg) - lightweight alloys
applications: alloys, automotive, aerospace
atomic number: 12
symbol: Mg

SECONDARY_METABOLITE
type: Class
title: metabolite
subclass of: ProductTypeEnum
definition: Secondary metabolite
category: Specialty chemical

NEONICOTINOID
type: Class
title: neonicotinoid insectide
subclass of: PesticideTypeEnum
definition: Neonicotinoid pesticide

NONMETALS
type: Class
title: nonmetal atom
subclass of: ElementFamilyEnum
definition: Non-metallic elements
elements: H, C, N, O, F, P, S, Cl, Se, Br, I

ORGANOCHLORINE
type: Class
title: organochlorine insecticide
subclass of: PesticideTypeEnum
definition: Organochlorine pesticide

ORGANOPHOSPHATE
type: Class
title: organophosphate insecticide
subclass of: PesticideTypeEnum
definition: Organophosphate pesticide

OZONE
type: Class
subclass of: AirPollutantEnum
definition: Ground-level ozone (O3)

POLYKETIDE
type: Class
subclass of: BgcCategoryEnum
definition: Polyketide biosynthetic gene clusters
biosynthetic enzyme: Polyketide synthase (PKS)
definition: Natural products containing alternating carbonyl and methylene groups
examples: Erythromycin, lovastatin, rapamycin

PYRETHROID
type: Class
title: pyrethroid insecticide
subclass of: PesticideTypeEnum
definition: Pyrethroid pesticide

SPHINGOLIPIDS
type: Class
subclass of: LipidCategory
alternative label: sphingolipid
definition: Sphingolipids

TRANSITION_METALS
type: Class
title: transition element atom
subclass of: ElementFamilyEnum
definition: d-block elements
groups: 3-12

FIVE_METHYL_C
type: Class
title: 5-methylcytosine
subclass of: NucleotideModificationEnum
definition: 5-methylcytosine
function: gene regulation
symbol: m5C
type: DNA methylation

ARSENIC
type: Class
title: arsenic atom
subclass of: CriticalMineral
definition: Arsenic (As) - semiconductors and alloys
applications: semiconductors, wood preservatives
atomic number: 33
symbol: As

VANADIUM
type: Class
title: vanadium atom
subclass of: CriticalMineral
definition: Vanadium (V) - steel alloys and batteries
applications: steel alloys, flow batteries, catalysts
atomic number: 23
symbol: V

GLYPHOSATE
type: Class
subclass of: PesticideTypeEnum
definition: Glyphosate herbicide

TUNGSTEN
type: Class
subclass of: CriticalMineral
definition: Tungsten (W) - hard metals and electronics
applications: cutting tools, electronics, alloys
atomic number: 74
symbol: W

CHROMIUM
type: Class
title: chromium atom
subclass of: CriticalMineral
definition: Chromium (Cr) - stainless steel and alloys
applications: stainless steel, superalloys, plating
atomic number: 24
symbol: Cr

BUTANOL
type: Class
title: butan-1-ol
subclass of: BiofuelType
alternative label: Biobutanol
definition: Four-carbon alcohol biofuel with higher energy density than ethanol.
chemical formula: C4H9OH

DIMETHYL_ETHER
type: Class
title: Bio-DME
subclass of: BiofuelType
alternative label: DME
definition: Dimethyl ether produced from biomass, usable as diesel substitute.

CHLOROPHYLL
type: Class
subclass of: FoodColoringEnum
definition: Chlorophyll (natural green)
e number: E140
hex: 4D7C0F
source: plants

DEUTERON
type: Class
subclass of: SubatomicParticleEnum
definition: Hydrogen-2 nucleus
charge: +1
composition: 1 proton, 1 neutron
mass: 1875.613 MeV/c²

TRITON
type: Class
subclass of: SubatomicParticleEnum
definition: Hydrogen-3 nucleus
charge: +1
composition: 1 proton, 2 neutrons
mass: 2808.921 MeV/c²

GOLD
type: Class
title: gold atom
subclass of: CommonMineral
definition: Gold (Au)
atomic number: 79
symbol: Au

SILICON_CARBIDE
type: Class
title: silicon carbide
subclass of: SemiconductorMaterialType
definition: Silicon carbide (SiC) wide-bandgap semiconductor for high-power applications

PRUSSIAN_BLUE
type: Class
title: ferric ferrocyanide
subclass of: TraditionalPigmentEnum
definition: Prussian blue (Ferric ferrocyanide)
chemical: Fe4[Fe(CN)6]3
discovered: 1706
hex: 003153

ALPHA_PARTICLE
type: Class
subclass of: SubatomicParticleEnum
definition: Helium-4 nucleus
charge: +2
composition: 2 protons, 2 neutrons
mass: 3727.379 MeV/c²

NEUTRON
type: Class
subclass of: SubatomicParticleEnum
definition: Neutral nucleon
charge: 0
composition: udd
mass: 939.565 MeV/c²
spin: 1/2
type: baryon

POSITRON
type: Class
subclass of: SubatomicParticleEnum
definition: Antiparticle of electron with +1 charge
charge: +1
mass: 0.51099895 MeV/c²
spin: 1/2
type: lepton

INDIUM
type: Class
title: indium atom
subclass of: CriticalMineral
definition: Indium (In) - displays and semiconductors
applications: LCD displays, semiconductors, solar panels
atomic number: 49
symbol: In

TELLURIUM
type: Class
title: tellurium atom
subclass of: CriticalMineral
definition: Tellurium (Te) - solar panels and thermoelectrics
applications: solar panels, thermoelectrics, alloys
atomic number: 52
symbol: Te

BERYLLIUM
type: Class
title: beryllium atom
subclass of: CriticalMineral
definition: Beryllium (Be) - aerospace and defense
applications: aerospace, defense, nuclear
atomic number: 4
symbol: Be

SILVER
type: Class
title: silver atom
subclass of: CommonMineral
definition: Silver (Ag)
atomic number: 47
symbol: Ag

ANTIMONY
type: Class
title: antimony atom
subclass of: CriticalMineral
definition: Antimony (Sb) - flame retardants and batteries
applications: flame retardants, batteries, alloys
atomic number: 51
symbol: Sb

RUTHENIUM
type: Class
title: ruthenium atom
subclass of: CriticalMineral
definition: Ruthenium (Ru) - electronics and catalysts
applications: electronics, catalysts, solar cells
atomic number: 44
category: PGM
symbol: Ru

BEETROOT_RED
type: Class
subclass of: FoodColoringEnum
alternative label: Betanin
definition: Beetroot red/Betanin
e number: E162
hex: BC2A4D
source: beets

ANNATTO
type: Class
subclass of: FoodColoringEnum
alternative label: bixin
definition: Annatto (natural orange)
e number: E160b
hex: FF6600
source: achiote seeds

NITROGEN_DIOXIDE
type: Class
subclass of: AirPollutantEnum
definition: Nitrogen dioxide (NO2)

BPA
type: Class
title: bisphenol A
subclass of: EndocrineDisruptorEnum
definition: Bisphenol A

VITAMIN
type: Class
title: vitamin (role)
subclass of: ProductTypeEnum
definition: Vitamin
category: Nutritional

COORDINATE
type: Class
title: coordination entity
subclass of: BondTypeEnum
definition: Coordinate/dative covalent bond
electrons from: one atom

ANTIBIOTIC
type: Class
title: antimicrobial agent
subclass of: ProductTypeEnum
definition: Antibiotic
category: Pharmaceutical

RODENTICIDE
type: Class
subclass of: PesticideTypeEnum
definition: Chemical used to kill rodents

BISMUTH
type: Class
title: bismuth atom
subclass of: CriticalMineral
definition: Bismuth (Bi) - pharmaceuticals and alloys
applications: pharmaceuticals, cosmetics, alloys
atomic number: 83
symbol: Bi

CHALCOGENS
type: Class
title: chalcogen
subclass of: ElementFamilyEnum
definition: Group 16 elements
elements: O, S, Se, Te, Po
group: 16

NOBLE_GASES
type: Class
title: neon atom
subclass of: ElementFamilyEnum
definition: Group 18 elements
elements: He, Ne, Ar, Kr, Xe, Rn
group: 18

STRONTIUM
type: Class
title: strontium atom
subclass of: CriticalMineral
definition: Strontium (Sr) - magnets and pyrotechnics
applications: magnets, pyrotechnics, medical
atomic number: 38
symbol: Sr

YTTRIUM
type: Class
title: yttrium atom
subclass of: CriticalMineral
definition: Yttrium (Y) - phosphors and ceramics
applications: LEDs, superconductors, ceramics
atomic number: 39
symbol: Y

TITANIUM
type: Class
title: titanium atom
subclass of: CriticalMineral
definition: Titanium (Ti) - aerospace and defense
applications: aerospace, medical implants, pigments
atomic number: 22
symbol: Ti

ZIRCONIUM
type: Class
title: zirconium atom
subclass of: CriticalMineral
definition: Zirconium (Zr) - nuclear and ceramics
applications: nuclear reactors, ceramics, alloys
atomic number: 40
symbol: Zr

HAFNIUM
type: Class
title: hafnium atom
subclass of: CriticalMineral
definition: Hafnium (Hf) - nuclear and semiconductors
applications: nuclear control rods, superalloys
atomic number: 72
symbol: Hf

NIOBIUM
type: Class
title: niobium atom
subclass of: CriticalMineral
definition: Niobium (Nb) - steel alloys and superconductors
applications: steel alloys, superconductors, capacitors
atomic number: 41
symbol: Nb

TANTALUM
type: Class
title: tantalum atom
subclass of: CriticalMineral
definition: Tantalum (Ta) - capacitors and superalloys
applications: capacitors, medical implants, superalloys
atomic number: 73
symbol: Ta

RHODIUM
type: Class
title: rhodium atom
subclass of: CriticalMineral
definition: Rhodium (Rh) - catalysts and electronics
applications: catalysts, electronics, glass
atomic number: 45
category: PGM
symbol: Rh

PALLADIUM
type: Class
subclass of: CriticalMineral
definition: Palladium (Pd) - catalysts and electronics
applications: catalysts, electronics, dentistry
atomic number: 46
category: PGM
symbol: Pd

TECHNETIUM_99
type: Class
subclass of: RadioactiveContaminantType
definition: Technetium-99, a long-lived beta emitter produced in fission reactors
decay mode: beta
half life: 211100 years

PM
type: Class
title: Promethium
subclass of: ExtractableTargetElement
alternative label: promethium atom
definition: Radioactive rare earth element (atomic number 61) used in nuclear batteries and luminous paint

SM
type: Class
title: Samarium
subclass of: ExtractableTargetElement
alternative label: samarium atom
definition: Light rare earth element (atomic number 62) used in samarium-cobalt magnets and cancer treatment

GD
type: Class
title: Gadolinium
subclass of: ExtractableTargetElement
alternative label: gadolinium atom
definition: Heavy rare earth element (atomic number 64) used in MRI contrast agents and nuclear reactor control rods

ER
type: Class
title: Erbium
subclass of: ExtractableTargetElement
alternative label: erbium
definition: Heavy rare earth element (atomic number 68) used in fiber optic amplifiers and lasers

TM
type: Class
title: Thulium
subclass of: ExtractableTargetElement
alternative label: thulium atom
definition: Heavy rare earth element (atomic number 69) used in portable X-ray devices and lasers

YB
type: Class
title: Ytterbium
subclass of: ExtractableTargetElement
alternative label: ytterbium
definition: Heavy rare earth element (atomic number 70) used in metallurgy, lasers, and atomic clocks

LU
type: Class
title: Lutetium
subclass of: ExtractableTargetElement
alternative label: lutetium atom
definition: Heavy rare earth element (atomic number 71) used in PET scan detectors and cancer treatment

THORIUM_FUEL
type: Class
title: Thorium-Based Fuel
subclass of: NuclearFuelTypeEnum
alternative label: Thorium fuel
alternative label: thorium
definition: Fuel containing thorium-232 as fertile material
abundance: more abundant than uranium
fertile isotope: Th-232
fissile product: U-233
proliferation resistance: high

PLUTONIUM
type: Class
title: plutonium atom
subclass of: RadioactiveContaminantType
definition: Plutonium isotopes, alpha emitters with long half-lives and high radiotoxicity
decay mode: alpha

AMERICIUM_241
type: Class
title: americium atom
subclass of: RadioactiveContaminantType
definition: Americium-241, an alpha emitter with a half-life of approximately 432 years
decay mode: alpha
half life: 432.2 years

PLATINUM
type: Class
title: platinum(0)
subclass of: CriticalMineral
definition: Platinum (Pt) - catalysts and electronics
applications: catalysts, jewelry, electronics
atomic number: 78
category: PGM
symbol: Pt

GRAPHITE
type: Class
subclass of: CriticalMineral
definition: Graphite - battery anodes and refractories
applications: batteries, lubricants, refractories
formula: C

RADON_222
type: Class
title: radon-222 atom
subclass of: RadionuclideEnum
definition: Radioactive noble gas produced by decay of radium-226. Major contributor to natural background radiation and indoor air quality concern.
decay mode: alpha
half life: 3.82 days
health concern: lung cancer risk from inhalation
parent: Ra-226
symbol: Rn-222

METALLOIDS
type: Class
title: s-block element atom
subclass of: ElementFamilyEnum
definition: Elements with intermediate properties
elements: B, Si, Ge, As, Sb, Te, Po

D_BLOCK
type: Class
title: d-block element atom
subclass of: PeriodicTableBlockEnum
definition: d-block elements (transition metals)
groups: 3-12
valence orbital: d

F_BLOCK
type: Class
title: f-block element atom
subclass of: PeriodicTableBlockEnum
definition: f-block elements (lanthanides and actinides)
series: lanthanides, actinides
valence orbital: f

S_BLOCK
type: Class
title: s-block molecular entity
subclass of: PeriodicTableBlockEnum
definition: s-block elements (groups 1 and 2)
groups: 1,2
valence orbital: s

P_BLOCK
type: Class
title: p-block molecular entity
subclass of: PeriodicTableBlockEnum
definition: p-block elements (groups 13-18)
groups: 13,14,15,16,17,18
valence orbital: p

HELIUM
type: Class
title: helium(0)
subclass of: CriticalMineral
definition: Helium (He) - cryogenics and electronics
applications: MRI, semiconductors, aerospace
atomic number: 2
symbol: He

BIOPOLYMER
type: Class
title: biomacromolecule
subclass of: ProductTypeEnum
definition: Biopolymer (PHA, PLA, etc.)
category: Material

AMINO_ACID
type: Class
subclass of: ProductTypeEnum
definition: Amino acid
category: Nutritional

LANTHANIDES
type: Class
title: titanium group molecular entity
subclass of: ElementFamilyEnum
definition: Lanthanide series
atomic numbers: 57-71

ACTINIDES
type: Class
title: fuconates
subclass of: ElementFamilyEnum
definition: Actinide series
atomic numbers: 89-103

POLYCYCLIC_AROMATIC_HYDROCARBONS
type: Class
title: polycyclic arene
subclass of: AirPollutantEnum
definition: Polycyclic aromatic hydrocarbons (PAHs)

CONGO_RED
type: Class
subclass of: IndustrialDyeEnum
definition: Congo red
chemical: C32H22N6Na2O6S2
hex: CC0000
use: pH indicator, textile

TERPENE
type: Class
subclass of: BgcCategoryEnum
definition: Terpene biosynthetic gene clusters
biosynthetic enzyme: Terpene synthase
definition: Hydrocarbons derived from isoprene units
examples: Limonene, carotenoids, taxol

STEROIDS_AND_DERIVATIVES
type: Class
subclass of: LipidCategory
alternative label: steroid
definition: Steroids and derivatives
narrow match: CHEBI_15889

FLUORSPAR
type: Class
title: calcium difluoride
subclass of: CriticalMineral
definition: Fluorspar (CaF2) - steel and aluminum production
applications: steel, aluminum, refrigerants
formula: CaF2
mineral name: fluorite

GLYCEROLIPIDS
type: Class
subclass of: LipidCategory
alternative label: glycerolipid
definition: Glycerolipids

W_BOSON
type: Class
title: composite particle
subclass of: SubatomicParticleEnum
definition: Force carrier for weak interaction
charge: ±1
mass: 80.379 GeV/c²
spin: 1
type: gauge boson

Z_BOSON
type: Class
title: hadron
subclass of: SubatomicParticleEnum
definition: Force carrier for weak interaction
charge: 0
mass: 91.1876 GeV/c²
spin: 1
type: gauge boson

ZINC_WHITE
type: Class
title: zinc oxide
subclass of: TraditionalPigmentEnum
definition: Zinc white (Zinc oxide)
chemical: ZnO
hex: FEFEFE

CARBON_14
type: Class
title: carbon-14 atom
subclass of: RadionuclideEnum
definition: Cosmogenic radionuclide used in radiocarbon dating. Produced by cosmic ray interactions in atmosphere.
decay mode: beta
half life: 5730 years
symbol: C-14
use: radiocarbon dating

POLONIUM_210
type: Class
title: polonium-210 atom
subclass of: RadionuclideEnum
definition: Highly radioactive alpha emitter in uranium decay series. Found in tobacco smoke.
decay mode: alpha
half life: 138 days
health concern: lung cancer from tobacco
symbol: Po-210

GLYCEROPHOSPHOLIPIDS
type: Class
subclass of: LipidCategory
alternative label: glycerophospholipid
definition: Glycerophospholipids

CARBAMATE
type: Class
title: carbamate insecticide
subclass of: PesticideTypeEnum
definition: Carbamate pesticide

ACID
type: Class
title: Bronsted acid
subclass of: BronstedAcidBaseRoleEnum
definition: Proton donor
definition: species that donates H+

BASE
type: Class
title: Bronsted base
subclass of: BronstedAcidBaseRoleEnum
definition: Proton acceptor
definition: species that accepts H+

TURMERIC
type: Class
title: curcumin
subclass of: FoodColoringEnum
definition: Turmeric/Curcumin (natural yellow)
e number: E100
hex: F0E442
source: turmeric root

CRYSTAL_VIOLET
type: Class
subclass of: IndustrialDyeEnum
definition: Crystal violet/Gentian violet
chemical: C25H30ClN3
hex: 9400D3
use: gram staining

EIGHT_OXO_G
type: Class
title: 8-oxoguanine
subclass of: NucleotideModificationEnum
definition: 8-oxoguanine
pairs with: A or C
symbol: 8-oxoG
type: oxidative damage

MINERAL
type: Class
subclass of: SESARMaterialType
definition: Mineral specimen

HALOGENS
type: Class
title: idopyranuronic acid
subclass of: ElementFamilyEnum
definition: Group 17 elements
elements: F, Cl, Br, I, At
group: 17

PLATINUM
type: Class
title: elemental platinum
subclass of: CommonMineral
definition: Platinum (Pt)
atomic number: 78
symbol: Pt

GALLIUM
type: Class
title: gallium atom
subclass of: CriticalMineral
definition: Gallium (Ga) - semiconductors and LEDs
applications: semiconductors, LEDs, solar cells
atomic number: 31
symbol: Ga

HO
type: Class
title: Holmium
subclass of: ExtractableTargetElement
alternative label: holmium atom
definition: Heavy rare earth element (atomic number 67) used in lasers and magnetic flux concentrators

IRIDIUM
type: Class
title: iridium atom
subclass of: CriticalMineral
definition: Iridium (Ir) - electronics and catalysts
applications: spark plugs, electronics, catalysts
atomic number: 77
category: PGM
symbol: Ir

NANOTUBE
type: Class
subclass of: NanostructureMorphologyEnum
definition: Cylindrical nanostructure
dimensions: 1D
examples: carbon nanotubes

NANOPARTICLE
type: Class
subclass of: NanostructureMorphologyEnum
definition: Particle with nanoscale dimensions
dimensions: 0D
size range: 1-100 nm

NANOROD
type: Class
subclass of: NanostructureMorphologyEnum
definition: Rod-shaped nanostructure
aspect ratio: 3-20
dimensions: 1D

CADMIUM_YELLOW
type: Class
title: cadmium selenide
subclass of: TraditionalPigmentEnum
definition: Cadmium yellow (Cadmium sulfide)
chemical: CdS
hex: FFF600
warning: toxic

CADMIUM_RED
type: Class
title: cadmium selenide nanoparticle
subclass of: TraditionalPigmentEnum
definition: Cadmium red (Cadmium selenide)
chemical: CdSe
hex: E30022
warning: toxic

QUANTUM_DOT
type: Class
subclass of: NanostructureMorphologyEnum
definition: Semiconductor nanocrystal
dimensions: 0D
property: quantum confinement

IONIC
type: Class
title: organic molecular entity
subclass of: BondTypeEnum
definition: Ionic bond
type: electrostatic

TITANIUM_WHITE
type: Class
title: titanium dioxide nanoparticle
subclass of: TraditionalPigmentEnum
definition: Titanium white (Titanium dioxide)
chemical: TiO2
discovered: 1916
hex: FFFFFF

EOSIN
type: Class
subclass of: IndustrialDyeEnum
alternative label: eosin YS dye
definition: Eosin Y
chemical: C20H6Br4Na2O5
hex: FF6B6B
use: histology stain

PHARMACEUTICALS
type: Class
title: pharmaceutical
subclass of: WaterContaminantEnum
definition: Pharmaceutical residues

IODINE_129
type: Class
title: iodine-129 atom
subclass of: RadioactiveContaminantType
definition: Iodine-129, a long-lived beta and gamma emitter produced in nuclear fission
decay mode: beta, gamma
half life: 15.7 million years

PCB
type: Class
title: polychlorobiphenyl
subclass of: EndocrineDisruptorEnum
definition: Polychlorinated biphenyls

POLYMER
type: Class
title: Polymer
subclass of: MaterialClassEnum
definition: Large molecules composed of repeating units

ORGANIC_ACID
type: Class
subclass of: ProductTypeEnum
definition: Organic acid (citric, lactic, etc.)
category: Chemical

MALACHITE_GREEN
type: Class
subclass of: IndustrialDyeEnum
definition: Malachite green
chemical: C23H25ClN2
hex: 0BDA51
use: biological stain

FIVE_HYDROXY_METHYL_C
type: Class
title: 5-(hydroxymethyl)cytosine
subclass of: NucleotideModificationEnum
definition: 5-hydroxymethylcytosine
function: demethylation intermediate
symbol: hmC
type: DNA modification

RADIUM_228
type: Class
title: Radium-228
subclass of: RadionuclideEnum
definition: Radioactive isotope in the thorium decay series.
decay mode: beta
half life: 5.75 years
symbol: Ra-228

INDIUM_PHOSPHIDE
type: Class
title: Indium phosphide
subclass of: SemiconductorMaterialType
definition: Indium phosphide (InP) compound semiconductor for optoelectronics and fiber communications

FD_C_BLUE_1
type: Class
title: Brilliant Blue
subclass of: FoodColoringEnum
definition: FD&C Blue No. 1 (Brilliant Blue)
e number: E133
hex: 0033FF
use: beverages, candies

MOLASSES
type: Class
subclass of: FeedstockTypeEnum
definition: Molasses
complex medium: true
source: Sugar processing byproduct

PHASE_CONTRAST_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
definition: Phase-contrast microscopy

ELECTRON_MICROSCOPY
type: Class
title: electron microscopy
subclass of: NuclearForensicsMethodType
definition: Microscopic imaging and analysis of nuclear material morphology and microstructure

SEM
type: Class
title: scanning electron microscopy
subclass of: MicroscopyMethodEnum
alternative label: Scanning Electron Microscopy
definition: Scanning Electron Microscopy

TEM
type: Class
title: transmission electron microscopy
subclass of: MicroscopyMethodEnum
alternative label: Transmission Electron Microscopy
definition: Transmission Electron Microscopy

FLUORESCENCE_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
definition: Fluorescence microscopy assay

CONFOCAL
type: Class
title: confocal fluorescence microscopy assay
subclass of: MicroscopyMethodEnum
alternative label: CLSM
alternative label: Confocal
definition: Confocal Laser Scanning Microscopy

OPTICAL
type: Class
title: light microscopy assay
subclass of: MicroscopyMethodEnum
alternative label: Light Microscopy
alternative label: Optical Microscopy
definition: Optical/Light Microscopy

BRIGHTFIELD_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
definition: Brightfield microscopy imaging

STM
type: Class
title: scanning tunnelling microscopy
subclass of: MicroscopyMethodEnum
alternative label: Scanning Tunneling Microscopy
definition: Scanning Tunneling Microscopy

XRD
type: Class
subclass of: SpectroscopyMethodEnum
alternative label: X-ray Diffraction
definition: X-ray Diffraction

X_RAY_CRYSTALLOGRAPHY
type: Class
title: single crystal X-ray diffraction
subclass of: StructuralBiologyTechnique
definition: X-ray crystallography
aliases: XRC, macromolecular crystallography
resolution range: 1-4 Å typical

SANS
type: Class
title: small-angle neutron scattering
subclass of: StructuralBiologyTechnique
definition: Small-angle neutron scattering
advantages: contrast variation with deuteration

SAXS
type: Class
title: small-angle X-ray scattering
subclass of: StructuralBiologyTechnique
definition: Small-angle X-ray scattering
information: low-resolution structure, conformational changes

WAXS
type: Class
title: wide-angle X-ray scattering
subclass of: StructuralBiologyTechnique
definition: Wide-angle X-ray scattering

ALPHA_SPECTROSCOPY
type: Class
title: alpha-particle spectroscopy
subclass of: NuclearForensicsMethodType
definition: Measurement of alpha particle energies for characterizing alpha-emitting radionuclides

UV_VIS
type: Class
title: ultraviolet-visible spectrophotometry
subclass of: SpectroscopyMethodEnum
alternative label: UV-Vis
alternative label: UV-Visible
definition: Ultraviolet-Visible Spectroscopy

EDS
type: Class
title: energy-dispersive X-ray emission spectroscopy
subclass of: SpectroscopyMethodEnum
alternative label: EDX
alternative label: EDXS
definition: Energy Dispersive X-ray Spectroscopy

XPS
type: Class
subclass of: SpectroscopyMethodEnum
alternative label: ESCA
alternative label: X-ray Photoelectron Spectroscopy
definition: X-ray Photoelectron Spectroscopy

GAMMA_SPECTROSCOPY
type: Class
title: gamma-ray spectroscopy
subclass of: NuclearForensicsMethodType
definition: Measurement of gamma-ray energies emitted by radioactive materials for isotope identification

GAS_CHROMATOGRAPHY_MASS_SPECTROMETRY
type: Class
subclass of: ChromatographyType
definition: Gas chromatography-mass spectrometry

CONFOCAL_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
definition: Confocal laser scanning microscopy

MAGNETIC_RESONANCE_SPECTROSCOPY
type: Class
subclass of: ImagingAssayEnum
alternative label: MRS
definition: Magnetic resonance spectroscopy

TANDEM_MASS_SPECTROMETRY
type: Class
subclass of: ChromatographyType
definition: Tandem mass spectrometry

FTIR
type: Class
title: Fourier transform infrared spectroscopy
subclass of: SpectroscopyMethodEnum
alternative label: FT-IR
definition: Fourier Transform Infrared Spectroscopy

RAMAN
type: Class
title: Raman
subclass of: SpectroscopyMethodEnum
alternative label: Raman Spectroscopy
definition: Raman Spectroscopy

DSC
type: Class
subclass of: ThermalAnalysisMethodEnum
alternative label: Differential Scanning Calorimetry
definition: Differential Scanning Calorimetry

DTA
type: Class
subclass of: ThermalAnalysisMethodEnum
alternative label: Differential Thermal Analysis
definition: Differential Thermal Analysis

TGA
type: Class
title: thermogravimetry
subclass of: ThermalAnalysisMethodEnum
alternative label: Thermogravimetric Analysis
definition: Thermogravimetric Analysis

NEUTRON_CRYSTALLOGRAPHY
type: Class
title: neutron diffraction
subclass of: StructuralBiologyTechnique
definition: Neutron crystallography
advantages: hydrogen positions, deuteration studies

LC_MS_MS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: LC-MS/MS
alternative label: liquid chromatography/tandem mass spectrometry
definition: Liquid chromatography-tandem mass spectrometry

NEUTRON_ACTIVATION_ANALYSIS
type: Class
title: neutron activation analysis
subclass of: NuclearForensicsMethodType
definition: Elemental analysis by irradiating samples with neutrons and measuring induced radioactivity

AUTORADIOGRAPHY
type: Class
subclass of: ImagingAssayEnum
definition: Autoradiography imaging

FTIR_SPECTROSCOPY
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: FTIR spectroscopy
definition: Fourier-transform infrared spectroscopy

OPTICAL_COHERENCE_TOMOGRAPHY
type: Class
subclass of: ImagingAssayEnum
alternative label: OCT
definition: Optical coherence tomography

CHROMATOGRAPHY
type: Class
subclass of: DownstreamProcessEnum
definition: Chromatographic separation
types: Ion exchange, affinity, size exclusion

HPLC
type: Class
subclass of: CellBasedAssayEnum
definition: High-performance liquid chromatography

MBE
type: Class
title: molecular beam epitaxy
subclass of: CrystalGrowthMethodEnum
alternative label: Molecular Beam Epitaxy
definition: Molecular Beam Epitaxy

INJECTION_MOLDING
type: Class
title: injection moulding
subclass of: ManufacturingProcessType
definition: Forcing molten material into a mold cavity where it cools and hardens

DIP_COATING
type: Class
title: Dip Coating
subclass of: SynthesisMethodEnum
definition: Coating by dipping in solution

SPIN_COATING
type: Class
title: Spin Coating
subclass of: SynthesisMethodEnum
definition: Coating by spinning substrate

DISTILLATION
type: Class
title: continuous distillation
subclass of: DownstreamProcessEnum
definition: Distillation
principle: Boiling point difference

DRYING
type: Class
title: direct drying
subclass of: DownstreamProcessEnum
definition: Drying operations
types: Spray, freeze, vacuum

EVAPORATION
type: Class
subclass of: DownstreamProcessEnum
definition: Evaporation/concentration
types: Falling film, MVR, TVR

EXTRACTION
type: Class
subclass of: DownstreamProcessEnum
definition: Liquid-liquid extraction
principle: Partitioning between phases

EXTRUSION
type: Class
subclass of: ManufacturingProcessType
definition: Forcing material through a die to create objects with a fixed cross-sectional profile

FILTRATION
type: Class
subclass of: DownstreamProcessEnum
definition: Filtration (micro/ultra/nano)
types: Dead-end, crossflow, depth

SYNCHROTRON
type: Class
subclass of: XRaySource
definition: Synchrotron radiation source
advantages: high intensity, tunable wavelength
brightness: 10^15-10^18 photons/s/mm²/mrad²

SPIN_ECHO
type: Class
title: Spin echo sequence
subclass of: MRISequenceTypeEnum
alternative label: spin echo pulse sequence
definition: Sequence using 180-degree refocusing pulse
artifact resistance: good
speed: slower
typical use: T2 imaging, reduced artifacts

CENTRIFUGATION
type: Class
title: analytical centrifugation
subclass of: DownstreamProcessEnum
definition: Centrifugal separation
principle: Density difference
types: Disk stack, tubular, decanter

PARTICLE_SIZE_DISTRIBUTION
type: Class
title: granulometry
subclass of: TailingCharacterizationType
definition: Measurement of the distribution of particle sizes in tailing material
methods: sieve analysis, laser diffraction, sedimentation

CCD
type: Class
title: charge-coupled-device detector
subclass of: Detector
definition: Charge-coupled device camera
applications: legacy EM, some crystallography

CRYO_EM
type: Class
title: cryogenic electron microscopy
subclass of: StructuralBiologyTechnique
definition: Cryo-electron microscopy
aliases: cryoEM, electron cryo-microscopy
resolution range: 2-30 Å typical

AUTOCLAVE
type: Class
title: autoclaving
subclass of: SterilizationMethodEnum
definition: Autoclave sterilization
pressure: 15 psi
temperature: 121°C

HIGH
type: Class
subclass of: CIOConfidenceLevel
alternative label: high confidence level
definition: A confidence level representing a high trust in an evidence.

MEDIUM
type: Class
subclass of: CIOConfidenceLevel
alternative label: medium confidence level
definition: A confidence level representing a moderate trust in an evidence.

LOW
type: Class
subclass of: CIOConfidenceLevel
alternative label: low confidence level
definition: A confidence level representing an absence of trust in an evidence.

COMPLETELY_EXECUTED
type: Class
title: completely executed planned process
subclass of: PlannedProcessCompletionStatus
definition: A planned process that was successfully completed as intended

FAILED
type: Class
title: failed planned process
subclass of: PlannedProcessCompletionStatus
definition: A planned process that did not complete successfully

HMB
type: Class
subclass of: DataUsePermissionEnum
alternative label: health or medical or biomedical research
definition: Health/medical/biomedical research only - does not include study of population origins or ancestry.

DS
type: Class
subclass of: DataUsePermissionEnum
alternative label: disease specific research
definition: Disease-specific research - use allowed only for research related to specified disease(s). Should be coupled with disease ontology term.

RS
type: Class
subclass of: DataUseModifierEnum
alternative label: research specific restrictions
definition: Research-specific restrictions apply.

NMDS
type: Class
subclass of: DataUseModifierEnum
alternative label: no general methods research
definition: No general methods research - does not allow methods development.

NPUNCU
type: Class
subclass of: DataUseModifierEnum
alternative label: not for profit, non commercial use only
definition: Not-for-profit use only - use limited to not-for-profit organizations and non-commercial use.

IRB
type: Class
subclass of: DataUseModifierEnum
alternative label: ethics approval required
definition: Ethics approval required - requestor must provide documentation of local IRB/ERB approval.

GRU
type: Class
subclass of: DataUsePermissionEnum
alternative label: general research use
definition: General research use - allowed for any research purpose including health/medical/biomedical, fundamental biology, population origins, statistical methods development, and social-sciences research.

NPO
type: Class
subclass of: DataUseModifierEnum
alternative label: not for profit organisation use only
definition: Use limited to not-for-profit organizations only.

NCU
type: Class
subclass of: DataUseModifierEnum
alternative label: non-commercial use only
definition: Non-commercial use only - data can be used by commercial organizations for research but not commercial purposes.

HETEROTROPH
type: Class
title: heterotroph
subclass of: TrophicLevelEnum
definition: Organism that obtains carbon from organic compounds

AUTOTROPH
type: Class
title: autotroph
subclass of: TrophicLevelEnum
definition: Organism capable of synthesizing its own food from inorganic substances

CHEMOAUTOTROPH
type: Class
title: chemoautotroph
subclass of: TrophicLevelEnum
definition: Organism that obtains energy by oxidizing inorganic compounds

PHOTOAUTOTROPH
type: Class
title: photoautotroph
subclass of: TrophicLevelEnum
definition: Organism that uses light energy to synthesize organic compounds

PHOTOHETEROTROPH
type: Class
title: photoheterotroph
subclass of: TrophicLevelEnum
definition: Organism that uses light for energy but organic compounds for carbon

CHEMOHETEROTROPH
type: Class
title: chemoheterotroph
subclass of: TrophicLevelEnum
definition: Organism that obtains energy from organic compounds

CHEMOORGANOTROPH
type: Class
title: chemoorganotroph
subclass of: TrophicLevelEnum
definition: Organism that obtains energy from organic compounds

OLIGOTROPH
type: Class
title: oligotroph
subclass of: TrophicLevelEnum
definition: Organism that thrives in nutrient-poor environments

ANAEROBE
type: Class
title: anaerobe
subclass of: RelToOxygenEnum
definition: Organism that does not require oxygen for growth

AEROBE
type: Class
title: aerobe
subclass of: RelToOxygenEnum
definition: Organism that can survive and grow in an oxygenated environment

FACULTATIVE
type: Class
title: facultative anaerobe
subclass of: RelToOxygenEnum
definition: Organism that can grow with or without oxygen
note: Maps to facultative anaerobe in ECOCORE

OBLIGATE_ANAEROBE
type: Class
title: obligate anaerobe
subclass of: RelToOxygenEnum
definition: Organism that cannot grow in the presence of oxygen

OBLIGATE_AEROBE
type: Class
title: obligate aerobe
subclass of: RelToOxygenEnum
definition: Organism that requires oxygen to grow

RCA
type: Class
title: Inferred from Reviewed Computational Analysis
subclass of: GOEvidenceCode
alternative label: automatically integrated combinatorial evidence used in manual assertion
definition: Evidence from computational analysis that has been reviewed by a curator
is computational: true
is experimental: false
is high throughput: false
is manual: true

ISA
type: Class
title: Inferred from Sequence Alignment
subclass of: GOEvidenceCode
alternative label: sequence alignment evidence used in manual assertion
definition: Evidence from sequence alignment to an annotated gene product
is computational: true
is experimental: false
is high throughput: false
is manual: true

ISS
type: Class
title: Inferred from Sequence or structural Similarity
subclass of: GOEvidenceCode
alternative label: sequence similarity evidence used in manual assertion
definition: Evidence from sequence or structural similarity to another annotated gene product
is computational: true
is experimental: false
is high throughput: false
is manual: true

ISM
type: Class
title: Inferred from Sequence Model
subclass of: GOEvidenceCode
alternative label: match to sequence model evidence used in manual assertion
definition: Evidence from match to a sequence model (e.g., HMM, profile)
is computational: true
is experimental: false
is high throughput: false
is manual: true

ISO
type: Class
title: Inferred from Sequence Orthology
subclass of: GOEvidenceCode
alternative label: sequence orthology evidence used in manual assertion
definition: Evidence from orthology to an experimentally characterized gene product
is computational: true
is experimental: false
is high throughput: false
is manual: true

EXP
type: Class
title: Inferred from Experiment
subclass of: GOEvidenceCode
alternative label: experimental evidence used in manual assertion
definition: General experimental evidence supporting a GO annotation
is experimental: true
is high throughput: false
is manual: true

IEP
type: Class
title: Inferred from Expression Pattern
subclass of: GOEvidenceCode
alternative label: expression pattern evidence used in manual assertion
definition: Evidence from gene expression pattern data
is experimental: true
is high throughput: false
is manual: true

NAS
type: Class
title: Non-traceable Author Statement
subclass of: GOEvidenceCode
alternative label: author statement without traceable support used in manual assertion
definition: Evidence from an author statement that cannot be traced to the experimental source
is author statement: true
is experimental: false
is high throughput: false
is manual: true

TAS
type: Class
title: Traceable Author Statement
subclass of: GOEvidenceCode
alternative label: author statement supported by traceable reference used in manual assertion
definition: Evidence from an author statement in a published paper that can be traced to the original source
is author statement: true
is experimental: false
is high throughput: false
is manual: true

IC
type: Class
title: Inferred by Curator
subclass of: GOEvidenceCode
alternative label: curator inference used in manual assertion
definition: Evidence inferred by a curator based on existing annotations and biological knowledge
is curator inference: true
is experimental: false
is high throughput: false
is manual: true

ND
type: Class
title: No biological Data available
subclass of: GOEvidenceCode
alternative label: no evidence data found used in manual assertion
definition: Indicates that no biological data is available to support an annotation
is experimental: false
is high throughput: false
is manual: true

IDA
type: Class
title: Inferred from Direct Assay
subclass of: GOEvidenceCode
alternative label: direct assay evidence used in manual assertion
definition: Evidence from a direct assay for the presence or activity of a gene product
is experimental: true
is high throughput: false
is manual: true

IMP
type: Class
title: Inferred from Mutant Phenotype
subclass of: GOEvidenceCode
alternative label: mutant phenotype evidence used in manual assertion
definition: Evidence from the phenotype of a mutant allele
is experimental: true
is high throughput: false
is manual: true

IGI
type: Class
title: Inferred from Genetic Interaction
subclass of: GOEvidenceCode
alternative label: genetic interaction evidence used in manual assertion
definition: Evidence from genetic interaction between genes
is experimental: true
is high throughput: false
is manual: true

IGC
type: Class
title: Inferred from Genomic Context
subclass of: GOEvidenceCode
alternative label: genomic context evidence used in manual assertion
definition: Evidence from genomic context such as synteny or gene neighborhood
is computational: true
is experimental: false
is high throughput: false
is manual: true

IBA
type: Class
title: Inferred from Biological aspect of Ancestor
subclass of: GOEvidenceCode
alternative label: biological aspect of ancestor evidence used in manual assertion
definition: Evidence from conservation of biological aspect in an ancestral sequence
is experimental: false
is high throughput: false
is manual: true
is phylogenetic: true

IBD
type: Class
title: Inferred from Biological aspect of Descendant
subclass of: GOEvidenceCode
alternative label: biological aspect of descendant evidence used in manual assertion
definition: Evidence from conservation of biological aspect in a descendant sequence
is experimental: false
is high throughput: false
is manual: true
is phylogenetic: true

IKR
type: Class
title: Inferred from Key Residues
subclass of: GOEvidenceCode
alternative label: phylogenetic determination of loss of key residues evidence used in manual assertion
definition: Evidence from phylogenetic analysis showing loss of key residues
is experimental: false
is high throughput: false
is manual: true
is phylogenetic: true

IRD
type: Class
title: Inferred from Rapid Divergence
subclass of: GOEvidenceCode
alternative label: rapid divergence from ancestral sequence evidence used in manual assertion
definition: Evidence from rapid divergence from ancestral sequence
is experimental: false
is high throughput: false
is manual: true
is phylogenetic: true

IPI
type: Class
title: Inferred from Physical Interaction
subclass of: GOEvidenceCode
alternative label: physical interaction evidence used in manual assertion
definition: Evidence from physical interaction between gene products
is experimental: true
is high throughput: false
is manual: true

IEA
type: Class
title: Inferred from Electronic Annotation
subclass of: GOEvidenceCode
alternative label: evidence used in automatic assertion
definition: Evidence from automated electronic annotation pipelines without manual curation
is electronic: true
is experimental: false
is high throughput: false
is manual: false

HTP
type: Class
title: Inferred from High Throughput Experiment
subclass of: GOEvidenceCode
alternative label: high throughput evidence used in manual assertion
definition: Evidence from high-throughput experimental methods
is experimental: true
is high throughput: true
is manual: true

HMP
type: Class
title: Inferred from High Throughput Mutant Phenotype
subclass of: GOEvidenceCode
alternative label: high throughput mutant phenotypic evidence used in manual assertion
definition: Evidence from high-throughput mutant phenotype screening
is experimental: true
is high throughput: true
is manual: true

HGI
type: Class
title: Inferred from High Throughput Genetic Interaction
subclass of: GOEvidenceCode
alternative label: high throughput genetic interaction phenotypic evidence used in manual assertion
definition: Evidence from high-throughput genetic interaction screening
is experimental: true
is high throughput: true
is manual: true

HDA
type: Class
title: Inferred from High Throughput Direct Assay
subclass of: GOEvidenceCode
alternative label: high throughput direct assay evidence used in manual assertion
definition: Evidence from high-throughput direct assay experiments
is experimental: true
is high throughput: true
is manual: true

HEP
type: Class
title: Inferred from High Throughput Expression Pattern
subclass of: GOEvidenceCode
alternative label: high throughput expression pattern evidence used in manual assertion
definition: Evidence from high-throughput expression profiling
is experimental: true
is high throughput: true
is manual: true

ALLERGEN
type: Class
title: exposure to allergen
subclass of: HHEARExposureAssessedEnum
definition: Substances that can cause allergic reactions

ORGANOCHLORINE_COMPOUND
type: Class
title: exposure to organochlorine compound
subclass of: HHEARExposureAssessedEnum
definition: Organic compounds containing chlorine

MERCURY_SPECIES
type: Class
title: exposure to mercury
subclass of: HHEARExposureAssessedEnum
definition: Various forms of mercury compounds

TOBACCO_METABOLITE
type: Class
title: exposure to tobacco
subclass of: HHEARExposureAssessedEnum
definition: Metabolites of tobacco and nicotine

WEATHER
type: Class
title: exposure to weather
subclass of: HHEARExposureAssessedEnum
definition: Atmospheric conditions and weather-related exposures

TOBACCO_SMOKE_EXPOSURE
type: Class
title: exposure to tobacco smoking
subclass of: HHEARExposureAssessedEnum
definition: Exposure to primary or secondhand tobacco smoke

AIR_POLLUTANT
type: Class
title: exposure to air pollution
subclass of: HHEARExposureAssessedEnum
definition: Airborne pollutants including particulate matter and gaseous contaminants

ARSENIC_SPECIES
type: Class
title: exposure to arsenic
subclass of: HHEARExposureAssessedEnum
definition: Various forms of arsenic compounds

ENVIRONMENTAL_PHENOL
type: Class
title: exposure to phenol
subclass of: HHEARExposureAssessedEnum
definition: Phenolic compounds in the environment

ORGANOPHOSPHORUS_FLAME_RETARDANT
type: Class
title: exposure to organophosphorus compound
subclass of: HHEARExposureAssessedEnum
definition: Organophosphorus compounds used as flame retardants

PHTHALATE
type: Class
title: exposure to phthalate
subclass of: HHEARExposureAssessedEnum
definition: Phthalic acid esters used as plasticizers

PARABEN
type: Class
title: exposure to paraben
subclass of: HHEARExposureAssessedEnum
definition: 4-hydroxybenzoate esters used as preservatives

POLYBROMINATED_DIPHENYL_ETHER
type: Class
title: exposure to polybromodiphenyl ether
subclass of: HHEARExposureAssessedEnum
alternative label: PBDE
definition: Brominated aromatic ethers used as flame retardants

VOLATILE_ORGANIC_COMPOUND
type: Class
title: exposure to volatile organic compound
subclass of: HHEARExposureAssessedEnum
alternative label: VOC
definition: Organic compounds with high vapor pressure

PERFLUOROALKYL_AND_POLYFLUOROALKYL_SUBSTANCE
type: Class
title: exposure to perfluoroalkyl substance
subclass of: HHEARExposureAssessedEnum
alternative label: PFAS
definition: PFAS compounds including PFOA and PFOS

BROMINATED_FLAME_RETARDANT
type: Class
title: exposure to brominated flame retardant
subclass of: HHEARExposureAssessedEnum
definition: Organobromine compounds used as flame retardants

METAL
type: Class
title: exposure to heavy metal
subclass of: HHEARExposureAssessedEnum
definition: Metallic elements and compounds

MINE_TAILINGS
type: Class
title: mine tailing
subclass of: UnconventionalMineralResourceType
definition: Materials remaining after separating the valuable fraction from the uneconomic fraction of an ore

LAKE
type: Class
subclass of: SESARPhysiographicFeature
definition: Body of standing water

ESTUARY
type: Class
subclass of: SESARPhysiographicFeature
definition: Partially enclosed coastal body of water

CAVE
type: Class
subclass of: SESARPhysiographicFeature
definition: Natural underground chamber

MOUNTAIN_RANGE
type: Class
subclass of: SESARPhysiographicFeature
definition: Series of connected mountains

MOUNTAIN
type: Class
subclass of: SESARPhysiographicFeature
definition: Large natural elevation

DELTA
type: Class
subclass of: SESARPhysiographicFeature
definition: Landform at river mouth

GLACIERS
type: Class
title: glacier
subclass of: FAOSoilType
definition: Glaciers - areas covered by permanent ice
color rgb: 212,212,212
fao id: 12
symbol: GG

PERMAFROST
type: Class
subclass of: SubsurfaceFormationType
definition: Soil or rock that remains at or below freezing for two or more consecutive years

CANYON
type: Class
subclass of: SESARPhysiographicFeature
definition: Deep gorge with steep sides

HYDROTHERMAL_VENT
type: Class
subclass of: SESARPhysiographicFeature
definition: Fissure releasing geothermally heated water

SEAMOUNT
type: Class
subclass of: SESARPhysiographicFeature
definition: Underwater mountain

SUBMARINE_CANYON
type: Class
subclass of: SESARPhysiographicFeature
definition: Steep-sided valley on seafloor

VOLCANIC_SYSTEM
type: Class
title: volcanic field
subclass of: SubsurfaceEnergyResourceType
definition: Volcanic geological system with high geothermal gradients suitable for energy extraction

ROCK
type: Class
subclass of: SESARMaterialType
definition: Rock specimen

SOIL
type: Class
subclass of: SESARMaterialType
definition: Soil sample

SEDIMENT
type: Class
subclass of: SESARMaterialType
definition: Sediment sample

BRACKISH_WATER
type: Class
subclass of: WaterResourceType
definition: Water with salinity between freshwater and seawater

SURFACE_WATER
type: Class
subclass of: WaterResourceType
definition: Water found on the surface of the Earth in rivers, lakes, reservoirs, and wetlands

LIMESTONE
type: Class
subclass of: CommonMineral
definition: Limestone (CaCO3)
formula: CaCO3
use: cement, steel production

SHALE
type: Class
subclass of: SubsurfaceFormationType
definition: A fine-grained sedimentary rock formed from compacted clay or mud, often serving as a seal or source rock

OIL_RESERVOIR
type: Class
title: oil reservoir
subclass of: SubsurfaceEnergyResourceType
definition: Subsurface formation containing fluid hydrocarbons in porous or fractured rock

ARENOSOLS
type: Class
title: arenosol
subclass of: FAOSoilType
definition: Arenosols - sandy soils with weak horizon development
color rgb: 245,212,161
fao id: 4
symbol: AR

ANDOSOLS
type: Class
title: andosol
subclass of: FAOSoilType
definition: Andosols - soils developed from volcanic ash with unique physical and chemical properties
color rgb: 254,0,0
fao id: 3
symbol: AN

CRYOSOLS
type: Class
title: cryosol
subclass of: FAOSoilType
definition: Cryosols - soils formed under permafrost conditions
color rgb: 75,61,172
fao id: 9
symbol: CR

GLEYSOLS
type: Class
title: gleysol
subclass of: FAOSoilType
definition: Gleysols - soils with permanent or temporary waterlogging
color rgb: 128,131,217
fao id: 13
symbol: GL

SOLONCHAKS
type: Class
title: solonchak
subclass of: FAOSoilType
definition: Solonchaks - soils with high salt content
color rgb: 254,0,250
fao id: 28
symbol: SC

VERTISOLS
type: Class
title: vertisol
subclass of: FAOSoilType
definition: Vertisols - clay-rich soils with shrink-swell properties
color rgb: 197,0,255
fao id: 33
symbol: VR

HISTOSOLS
type: Class
title: peat soil
subclass of: FAOSoilType
definition: Histosols - soils formed from organic materials (peat soils)
color rgb: 112,107,102
fao id: 15
symbol: HS

AQUIFER
type: Class
subclass of: SubsurfaceFormationType
definition: An underground layer of water-bearing permeable rock or unconsolidated materials from which groundwater can be extracted

PM10
type: Class
title: respirable suspended particulate matter
subclass of: AirPollutantEnum
definition: Respirable particulate matter with diameter less than 10 micrometers

PM2_5
type: Class
title: fine respirable suspended particulate matter
subclass of: AirPollutantEnum
definition: Fine particulate matter with diameter less than 2.5 micrometers

ULTRAFINE_PARTICLES
type: Class
title: ultrafine respirable suspended particulate matter
subclass of: AirPollutantEnum
definition: Ultrafine particles with diameter less than 100 nanometers

BUILDING_ENVELOPE
type: Class
subclass of: BuildingSystemType
definition: Exterior enclosure system including walls, roof, windows, and insulation

SALT_DOME
type: Class
subclass of: SubsurfaceFormationType
definition: A dome-shaped intrusion of evaporite minerals formed by upward movement of a salt body through overlying rock

PROPANE
type: Class
title: Propane/LPG
subclass of: EnergySource
alternative label: liquefied petroleum gas
emission free: false
fossil fuel: true
renewable: false

COASTAL_FLOOD
type: Class
title: coastal flood
subclass of: ENVO_01000710
subclass of: ExtremeWeatherEventEnum
definition: Flood caused by storm surge, high tides, or sea level rise affecting coastal areas.

RIVERINE_FLOOD
type: Class
title: riverine flood
subclass of: ENVO_01000710
subclass of: ExtremeWeatherEventEnum
definition: Flood occurring when river flow exceeds channel capacity, typically developing over hours to days.

FLASH_FLOOD
type: Class
title: flash flood
subclass of: ENVO_01000710
subclass of: ExtremeWeatherEventEnum
definition: Rapid flooding of low-lying areas within 6 hours of heavy rainfall or dam failure. Particularly dangerous due to sudden onset.

STORM_SURGE
type: Class
title: storm surge
subclass of: ExtremeWeatherEventEnum
definition: Abnormal rise in sea level during a storm, caused by wind pushing water toward shore. Major cause of hurricane-related deaths.
health impacts: drowning, injuries

FOREST_FIRE
type: Class
title: forest fire
subclass of: ENVO_01000787
subclass of: ExtremeWeatherEventEnum
definition: Wildfire occurring primarily in forested areas, producing dense smoke plumes that can travel long distances.

GAS_HYDRATE
type: Class
title: methane clathrate
subclass of: SubsurfaceEnergyResourceType
definition: Crystalline ice-like structures containing methane trapped in water molecule cages, found in ocean sediments and permafrost regions

BLIZZARD
type: Class
title: blizzard
subclass of: ExtremeWeatherEventEnum
definition: Severe snowstorm with sustained winds >= 35 mph and reduced visibility for 3+ hours. Creates dangerous travel conditions and cold exposure risk.
health impacts: hypothermia, injuries, carbon monoxide poisoning

MICROPLASTICS
type: Class
title: microplastic particle
subclass of: WaterContaminantEnum
definition: Microplastic particles

GROUNDWATER
type: Class
subclass of: WaterResourceType
definition: Underground water located in pore spaces of rock or unconsolidated deposits

ELECTROMAGNETIC_RADIATION
type: Class
title: electromagnetic radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Radiation during which waves of the electromagnetic field propagate through space

ACOUSTIC_RADIATION
type: Class
title: acoustic radiation
subclass of: AcousticRadiationTypeEnum
definition: Mechanical waves generated by oscillations that radiate through environmental material

METAL
type: Class
title: metallic material
subclass of: MaterialClassEnum
alternative label: Metal
definition: Metallic materials with metallic bonding

ICE
type: Class
subclass of: SESARMaterialType
definition: Frozen water or ice samples

PLACER
type: Class
title: alluvial deposit
subclass of: MiningType
definition: Placer mining
category: surface
target: alluvial deposits

STORMWATER
type: Class
subclass of: WaterResourceType
definition: Water that accumulates on surfaces during precipitation events and snow or ice melt

SEVERE_THUNDERSTORM
type: Class
title: convective storm
subclass of: ExtremeWeatherEventEnum
definition: Thunderstorm producing hail >= 1 inch, wind gusts >= 58 mph, or a tornado. Source of lightning, flash flooding, and wind damage.
health impacts: lightning injuries, wind injuries, flash flooding

TROPICAL_STORM
type: Class
title: tropical storm
subclass of: ExtremeWeatherEventEnum
definition: Atmospheric storm originating over tropical waters with organized circulation and sustained winds 39-73 mph. Precursor to hurricanes.
health impacts: injuries, drowning, displacement, mental health

OPEN_INLAND_WATER
type: Class
title: fresh water body
subclass of: FAOSoilType
definition: Open inland water - areas covered by permanent water bodies
color rgb: 0,0,255
fao id: 34
symbol: WR

EROSION
type: Class
subclass of: EnvironmentalImpact
definition: Erosion and sedimentation

STRIP_MINING
type: Class
title: opencast mining
subclass of: MiningType
definition: Strip mining
aliases: surface mining, opencast mining
category: surface

TORNADO
type: Class
title: tornado
subclass of: ExtremeWeatherEventEnum
definition: Violently rotating column of air extending from a thunderstorm to the ground. Characterized by extreme winds and path of destruction.
ef scale: EF0-EF5
health impacts: traumatic injuries, death, mental health

INFRASOUND
type: Class
title: infrasound
subclass of: AcousticRadiationTypeEnum
definition: Acoustic radiation at frequencies below the range of human hearing

OUTGOING_LONGWAVE_RADIATION
type: Class
title: outgoing longwave radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Infrared radiation emitted from a planet and atmosphere to space as thermal radiation

SHORTWAVE_RADIATION
type: Class
title: shortwave radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Radiant energy in visible, near-ultraviolet, or near-infrared spectra

SOLAR
type: Class
title: Solar energy (photovoltaic and thermal)
subclass of: EnergySource
alternative label: Solar radiation
related match: Solar Thermal Collector
brick label: Solar Thermal Collector
emission free: true
oeo label: solar energy
renewable: true

PHOTOSYNTHETICALLY_ACTIVE_RADIATION
type: Class
title: photosynthetically active radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Radiant energy in the 400-700 nm wave band usable by organisms for photosynthesis

REEF
type: Class
subclass of: SESARPhysiographicFeature
definition: Ridge of rock or coral near water surface

COAL_COMBUSTION_RESIDUALS
type: Class
title: coal ash
subclass of: UnconventionalMineralResourceType
definition: Residual materials from combustion of coal in power plants, including fly ash, bottom ash, and boiler slag

FLY_ASH
type: Class
title: fly ash
subclass of: UnconventionalMineralResourceType
definition: Fine powdery material composed mostly of silica collected from flue gases during coal combustion

SLAG
type: Class
title: boiler slag
subclass of: UnconventionalMineralResourceType
definition: Glassy material formed as a byproduct of smelting and refining metal ores

DEFORESTATION
type: Class
subclass of: EnvironmentalImpact
definition: Deforestation

AIR_POLLUTION
type: Class
subclass of: EnvironmentalImpact
definition: Air pollution
sources: dust, emissions

WATER_POLLUTION
type: Class
subclass of: EnvironmentalImpact
definition: Water pollution
types: acid mine drainage, heavy metals

ULTRASOUND_RADIATION
type: Class
title: ultrasound radiation
subclass of: AcousticRadiationTypeEnum
definition: Acoustic radiation at frequencies above 20 kHz

MID_INFRARED
type: Class
title: mid-infrared radiation
subclass of: InfraredRadiationTypeEnum
definition: Infrared radiation with frequencies 30-120 THz, wavelengths 2.5-10 micrometers

NEAR_INFRARED
type: Class
title: near-infrared radiation
subclass of: InfraredRadiationTypeEnum
definition: Infrared radiation with frequencies 120-400 THz, wavelengths 750 nm to 2.5 micrometers

FAR_INFRARED
type: Class
title: far-infrared radiation
subclass of: InfraredRadiationTypeEnum
definition: Infrared radiation with frequencies 300 GHz to 30 THz, wavelengths 10 micrometers to 1 mm

CERAMIC
type: Class
title: Ceramic
subclass of: MaterialClassEnum
definition: Inorganic non-metallic materials

OCCUPATIONAL
type: Class
title: occupational environment
subclass of: ExposureSourceEnum
definition: Workplace exposure
related match: ExO_0000093

DIESEL
type: Class
title: Diesel fuel
subclass of: EnergySource
alternative label: diesel fuel
emission free: false
fossil fuel: true
oeo label: diesel fuel
renewable: false

MEMBRANE
type: Class
title: membrane bioreactor
subclass of: BioreactorTypeEnum
definition: Membrane bioreactor
application: Cell retention, product separation
feature: Integrated membrane separation

THERMOSET
type: Class
title: thermoset polymer
subclass of: PolymerTypeEnum
alternative label: Thermoset
alternative label: thermosetting polymer
definition: Polymer that irreversibly hardens when cured

DROUGHT
type: Class
title: drought
subclass of: ExtremeWeatherEventEnum
definition: Extended period of deficient precipitation resulting in water shortage. Affects water quality, food security, and mental health.
health impacts: water quality, food insecurity, mental health
indices: PDSI, SPI, USDM

MICROWAVE_RADIATION
type: Class
title: microwave radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation that travels line-of-sight and may produce molecular rotation on contact

RADIO_WAVE_RADIATION
type: Class
title: radio wave radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation at wavelengths ranging from millimetre to kilometer scales

INFRARED_RADIATION
type: Class
title: infrared radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation emitted by molecular rotational-vibrational movements, wavelengths 760 nm to 1 mm

VISIBLE_SPECTRUM_RADIATION
type: Class
title: visible spectrum radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation at wavelengths between 380 nm and 760 nm

ULTRAVIOLET_RADIATION
type: Class
title: ultraviolet radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation at wavelengths between 10 nm and 400 nm

X_RAY_RADIATION
type: Class
title: X-ray radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Penetrating electromagnetic radiation emitted by high-energy electrons falling to lower energy states

GAMMA_RAY_RADIATION
type: Class
title: gamma-ray radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Penetrating electromagnetic radiation emitted from radioactive decay of atomic nuclei

IONIZING_RADIATION
type: Class
title: ionizing radiation
subclass of: ElectromagneticRadiationTypeEnum
definition: Electromagnetic radiation with sufficient energy to disrupt molecular bonds or alter electron numbers

BIOLOGICAL_AGENT
type: Class
subclass of: ExposureStressorTypeEnum
definition: Agent of biological origin (e.g., bacteria, viruses, allergens)

CHEMICAL_AGENT
type: Class
subclass of: ExposureStressorTypeEnum
definition: Agent of chemical origin (e.g., toxins, pollutants)

ECOLOGICAL_PERTURBATION
type: Class
subclass of: ExposureStressorTypeEnum
definition: Disruption to ecological systems (e.g., habitat degradation, climate change)

PHYSICAL_AGENT
type: Class
subclass of: ExposureStressorTypeEnum
definition: Physical source of energy that may cause injury (e.g., radiation, noise, temperature extremes)

PSYCHOSOCIAL_AGENT
type: Class
subclass of: ExposureStressorTypeEnum
definition: Agent that interferes with psychological development or social interaction

AIR_TRANSPORT_PATH
type: Class
subclass of: ExposureTransportPathEnum
definition: Transport path allowing stressor to interact with recipient via air

BIOMECHANICAL_AGENT
type: Class
subclass of: ExposureStressorTypeEnum
definition: Mechanical agent applied to biological systems (e.g., repetitive motion, physical strain)

HABITAT_DESTRUCTION
type: Class
title: habitat degradation
subclass of: EnvironmentalImpact
definition: Habitat destruction

WATER_TRANSPORT_PATH
type: Class
subclass of: ExposureTransportPathEnum
definition: Transport path involving interaction with stressor via water

SOIL_TRANSPORT_PATH
type: Class
subclass of: ExposureTransportPathEnum
definition: Transport path involving interaction with stressor via soil

BUILT_ENVIRONMENT
type: Class
title: Built Environment
subclass of: HHEARExposureAssessedEnum
definition: Human-made surroundings including buildings and infrastructure

INTERMITTENT
type: Class
subclass of: ExposureFrequencyEnum
definition: Exposure occurring at irregular intervals or periodically

CONTINUOUS
type: Class
subclass of: ExposureFrequencyEnum
definition: Exposure occurring without interruption

ABSORPTION
type: Class
subclass of: ExposureRouteEnum
definition: Exposure through absorption (dermal or other surface)

CURRENT_SMOKER
type: Class
subclass of: SmokingStatusEnum
definition: Person who is currently smoking tobacco

FORMER_SMOKER
type: Class
subclass of: SmokingStatusEnum
definition: Person who has smoked at least 100 cigarettes in their life but is not currently smoking

NEVER_SMOKER
type: Class
subclass of: SmokingStatusEnum
definition: Person who has smoked less than 100 cigarettes in their life

NON_SMOKER
type: Class
subclass of: SmokingStatusEnum
definition: Person who is not currently smoking

CHILDREN
type: Class
subclass of: StudyPopulationEnum
definition: Human children (pediatric population)

CONTROLS
type: Class
title: controls for disease or phenotype
subclass of: StudyPopulationEnum
definition: Control group participants without the disease or phenotype of interest

FETUSES
type: Class
subclass of: StudyPopulationEnum
definition: Human fetuses (prenatal population)

INFANTS_OR_NEWBORNS
type: Class
subclass of: StudyPopulationEnum
definition: Human infants and newborns

MILITARY_PERSONNEL
type: Class
subclass of: StudyPopulationEnum
definition: Active military personnel

MOTHERS
type: Class
subclass of: StudyPopulationEnum
definition: Human mothers

PREGNANT_FEMALES
type: Class
subclass of: StudyPopulationEnum
definition: Human females who are pregnant

VETERANS
type: Class
subclass of: StudyPopulationEnum
definition: Military veterans

WORKERS
type: Class
subclass of: StudyPopulationEnum
definition: Occupational workers

AMBIENT_ENVIRONMENT
type: Class
title: ambient environment route
subclass of: ExposureRouteEnum
definition: Exposure through contact with stressors in the ambient surroundings

AMBIENT_AQUATIC
type: Class
title: ambient acquatic environment route
subclass of: ExposureRouteEnum
definition: Exposure through ambient aquatic environment

AMBIENT_TERRESTRIAL
type: Class
title: ambient terrestrial environment route
subclass of: ExposureRouteEnum
definition: Exposure through ambient terrestrial environment

PASSIVE_INHALATION
type: Class
title: passive inhalation of the ambient environment route
subclass of: ExposureRouteEnum
definition: Passive inhalation of ambient environment stressors

ACTIVE_INHALATION
type: Class
title: active inhalation route
subclass of: ExposureRouteEnum
definition: Purposeful breathing or inhaling of stressor

GASTROINTESTINAL_TRACT
type: Class
title: gastrointestinal tract route
subclass of: ExposureRouteEnum
definition: Exposure through the gastrointestinal tract

GAVAGE
type: Class
title: gavage route
subclass of: ExposureRouteEnum
definition: Direct administration into the stomach

NEGATIVE_STAIN_EM
type: Class
title: negative staining
subclass of: StructuralBiologyTechnique
definition: Negative stain electron microscopy
resolution range: 15-30 Å typical

FOOD_INGREDIENT
type: Class
title: food ingredient
subclass of: BioproductCategoryType
definition: Biologically produced ingredients for food and beverage applications

YEAST_EXTRACT
type: Class
subclass of: FeedstockTypeEnum
definition: Yeast extract
complex nutrient: true
source: Autolyzed yeast

FOOD_PACKAGING
type: Class
title: Food Packaging
subclass of: HHEARExposureAssessedEnum
definition: Materials used to package food products

HOMOZYGOUS_ALTERNATE
type: Class
title: variant allele
subclass of: AllelicStateEnum
definition: Two alternate/variant alleles
symbol: hom alt

HOMOZYGOUS_REFERENCE
type: Class
title: reference allele
subclass of: AllelicStateEnum
definition: Two reference/wild-type alleles
symbol: hom ref

HEMIZYGOUS
type: Class
subclass of: AllelicStateEnum
definition: Only one allele present (e.g., X-linked in males)
note: Common for X-linked genes in males
symbol: hemi

HETEROZYGOUS
type: Class
subclass of: AllelicStateEnum
definition: Different alleles at a locus
symbol: het

HOMOZYGOUS
type: Class
subclass of: AllelicStateEnum
definition: Identical alleles at a locus
symbol: hom

COMPOUND_HETEROZYGOUS
type: Class
subclass of: AllelicStateEnum
definition: Two different heterozygous variants in same gene
symbol: comp het

CHECKPOINT_KINASE
type: Class
title: DNA damage checkpoint signaling
subclass of: CellCycleRegulator
definition: Checkpoint kinase
examples: CHK1, CHK2, ATR, ATM

G1_S_CHECKPOINT
type: Class
title: G1/S transition of mitotic cell cycle
subclass of: CellCycleCheckpoint
definition: G1/S checkpoint (Restriction point)
aliases: Start checkpoint, Restriction point, R point
regulator: p53, Rb

M
type: Class
title: M phase
subclass of: CellCyclePhase
definition: M phase (mitosis and cytokinesis)
aliases: mitotic phase, division phase
duration: ~1 hour

CYTOKINESIS
type: Class
subclass of: MitoticPhase
definition: Cytokinesis
features: cytoplasmic division
order: 6

F
type: Class
title: Molecular Function
subclass of: GOAspect
alternative label: MF
alternative label: molecular_function
definition: The activities that occur at the molecular level, such as catalysis or binding

CDK
type: Class
title: cyclin-dependent protein serine/threonine kinase activity
subclass of: CellCycleRegulator
definition: Cyclin-dependent kinase
examples: CDK1, CDK2, CDK4, CDK6

PHOSPHATASE
type: Class
title: phosphoprotein phosphatase activity
subclass of: CellCycleRegulator
definition: Cell cycle phosphatase
examples: CDC25A, CDC25B, CDC25C

CDK_INHIBITOR
type: Class
title: cyclin-dependent protein serine/threonine kinase inhibitor activity
subclass of: CellCycleRegulator
definition: CDK inhibitor
examples: p21, p27, p57

C
type: Class
title: Cellular Component
subclass of: GOAspect
alternative label: CC
alternative label: cellular_component
definition: The locations relative to cellular structures in which a gene product performs a function

DNA_REPAIR
type: Class
subclass of: DNADamageResponse
definition: DNA repair

PROTEOLYTIC_CLEAVAGE
type: Class
title: proteolysis
subclass of: ProteinModificationType
definition: Proteolytic cleavage

APOPTOTIC
type: Class
title: apoptotic process
subclass of: CellProliferationState
definition: Cells undergoing apoptosis
aliases: programmed cell death

PROMETAPHASE
type: Class
title: mitotic metaphase chromosome alignment
subclass of: MitoticPhase
definition: Prometaphase
features: nuclear envelope breakdown, kinetochore attachment
order: 2

MEIOSIS_I
type: Class
subclass of: MeioticPhase
definition: Meiosis I (reductional division)
result: reduction from diploid to haploid
succeeded by: MEIOSIS_II

PROPHASE_I
type: Class
title: meiotic prophase I
subclass of: MeioticPhase
definition: Prophase I
substages: leptotene, zygotene, pachytene, diplotene, diakinesis
succeeded by: METAPHASE_I

METAPHASE_I
type: Class
title: meiotic metaphase I
subclass of: MeioticPhase
definition: Metaphase I
feature: homologous pairs align
succeeded by: ANAPHASE_I

ANAPHASE_I
type: Class
title: meiotic anaphase I
subclass of: MeioticPhase
definition: Anaphase I
feature: homologous chromosomes separate
succeeded by: TELOPHASE_I

TELOPHASE_I
type: Class
title: meiotic telophase I
subclass of: MeioticPhase
definition: Telophase I
succeeded by: PROPHASE_II

MEIOSIS_II
type: Class
subclass of: MeioticPhase
definition: Meiosis II (equational division)
similarity: similar to mitosis

PROPHASE_II
type: Class
title: meiotic prophase II
subclass of: MeioticPhase
definition: Prophase II
succeeded by: METAPHASE_II

METAPHASE_II
type: Class
title: meiotic metaphase II
subclass of: MeioticPhase
definition: Metaphase II
succeeded by: ANAPHASE_II

ANAPHASE_II
type: Class
title: meiotic anaphase II
subclass of: MeioticPhase
definition: Anaphase II
feature: sister chromatids separate
succeeded by: TELOPHASE_II

TELOPHASE_II
type: Class
title: meiotic telophase II
subclass of: MeioticPhase
definition: Telophase II

P
type: Class
title: Biological Process
subclass of: GOAspect
alternative label: BP
alternative label: biological_process
definition: The larger processes accomplished by multiple molecular activities

PROLIFERATING
type: Class
title: cell population proliferation
subclass of: CellProliferationState
definition: Actively proliferating cells

CYCLIN
type: Class
title: cyclin-dependent protein serine/threonine kinase regulator activity
subclass of: CellCycleRegulator
definition: Cyclin proteins
examples: Cyclin A, B, D, E

DIFFERENTIATED
type: Class
title: cell differentiation
subclass of: CellProliferationState
definition: Terminally differentiated cells
examples: neurons, cardiomyocytes

G2_M_CHECKPOINT
type: Class
title: mitotic G1 DNA damage checkpoint signaling
subclass of: CellCycleCheckpoint
definition: G2/M checkpoint
function: ensures DNA properly replicated
regulator: p53, CHK1, CHK2

INTRA_S_CHECKPOINT
type: Class
title: mitotic intra-S DNA damage checkpoint signaling
subclass of: CellCycleCheckpoint
definition: Intra-S checkpoint
function: monitors DNA replication
regulator: ATR, CHK1

SPINDLE_CHECKPOINT
type: Class
title: spindle checkpoint signaling
subclass of: CellCycleCheckpoint
definition: Spindle checkpoint (M checkpoint)
aliases: SAC, spindle assembly checkpoint
function: ensures proper chromosome attachment
regulator: MAD2, BubR1

PROTEIN_COMPLEX
type: Class
title: protein-containing complex
subclass of: SampleType
definition: Protein-protein or protein-nucleic acid complex

APOPTOSIS_INDUCTION
type: Class
subclass of: DNADamageResponse
alternative label: positive regulation of apoptotic process
definition: Induction of apoptosis

ORGANELLE
type: Class
subclass of: SampleType
definition: Cellular organelle (mitochondria, chloroplast, etc.)

G1
type: Class
title: G1 phase
subclass of: CellCyclePhase
definition: G1 phase (Gap 1)
aliases: Gap 1, first gap phase
duration: variable (hours to years)

G2
type: Class
title: G2 phase
subclass of: CellCyclePhase
definition: G2 phase (Gap 2)
aliases: Gap 2, second gap phase
duration: 3-4 hours

S
type: Class
title: S phase
subclass of: CellCyclePhase
definition: S phase (DNA synthesis)
aliases: synthesis phase, DNA replication phase
duration: 6-8 hours

ANAPHASE
type: Class
subclass of: MitoticPhase
definition: Anaphase
features: sister chromatid separation
order: 4

METAPHASE
type: Class
subclass of: MitoticPhase
definition: Metaphase
features: chromosomes aligned at metaphase plate
order: 3

PROPHASE
type: Class
subclass of: MitoticPhase
definition: Prophase
features: chromatin condensation, spindle formation begins
order: 1

INTERPHASE
type: Class
subclass of: CellCyclePhase
definition: Interphase (G1, S, and G2 phases combined)
includes: G1, S, G2

TELOPHASE
type: Class
subclass of: MitoticPhase
definition: Telophase
features: nuclear envelope reformation
order: 5

E3_UBIQUITIN_LIGASE
type: Class
title: obsolete positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
subclass of: CellCycleRegulator
definition: E3 ubiquitin ligase (cell cycle)
examples: APC/C, SCF

NECROTIC
type: Class
title: obsolete necrotic cell death
subclass of: CellProliferationState
definition: Cells undergoing necrosis
type: uncontrolled cell death

SENESCENT
type: Class
title: cellular senescence
subclass of: CellProliferationState
definition: Senescent cells (permanently non-dividing)
markers: SA-β-gal, p16
reversible: false

SENESCENCE_INDUCTION
type: Class
title: stress-induced premature senescence
subclass of: DNADamageResponse
definition: Induction of senescence

INTERPRO2GO
type: Class
title: Gene Ontology annotation based on InterPro classification
subclass of: GOElectronicMethods

UNIPROTKB_KW2GO
type: Class
title: Gene Ontology annotation based on UniProtKB keywords
subclass of: GOElectronicMethods

DICTYBASE
type: Class
title: Gene Ontology annotation by DictyBase
subclass of: GOElectronicMethods

REACTOME
type: Class
title: Gene Ontology annotation based on Reactome pathways
subclass of: GOElectronicMethods

HAMAP_RULE2GO
type: Class
title: Gene Ontology annotation based on HAMAP family rules
subclass of: GOElectronicMethods

UNIPROTKB_SUBCELL2GO
type: Class
title: Gene Ontology annotation based on UniProtKB Subcellular Location vocabulary
subclass of: GOElectronicMethods

POMBASE
type: Class
title: Gene Ontology annotation by PomBase
subclass of: GOElectronicMethods

ZFIN
type: Class
title: Gene Ontology annotation by Zebrafish Information Network
subclass of: GOElectronicMethods

PANTHER
type: Class
title: Gene Ontology annotation based on PANTHER phylogenetic trees
subclass of: GOElectronicMethods

UNIPATHWAY2GO
type: Class
title: Gene Ontology annotation based on UniPathway vocabulary
subclass of: GOElectronicMethods

FLYBASE
type: Class
title: Gene Ontology annotation by FlyBase
subclass of: GOElectronicMethods

MGI
type: Class
title: Gene Ontology annotation by Mouse Genome Informatics
subclass of: GOElectronicMethods

SGD
type: Class
title: Gene Ontology annotation by Saccharomyces Genome Database
subclass of: GOElectronicMethods

UNIRULE2GO
type: Class
title: Gene Ontology annotation based on UniRule rules
subclass of: GOElectronicMethods

ENSEMBL_COMPARA
type: Class
title: Gene Ontology annotation based on Ensembl Compara orthology
subclass of: GOElectronicMethods

METACYC2GO
type: Class
title: Gene Ontology annotation based on MetaCyc pathways
subclass of: GOElectronicMethods

RFAM2GO
type: Class
title: Gene Ontology annotation based on Rfam classification
subclass of: GOElectronicMethods

RHEA2GO
type: Class
title: Gene Ontology annotation based on Rhea mapping
subclass of: GOElectronicMethods

MONOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having separate male and female flowers on the same plant

GYNOMONOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having both female and hermaphroditic flowers on the same plant

ANDROMONOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having both male and hermaphroditic flowers on the same plant

DIOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having male and female flowers on separate plants

GYNODIOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having female and hermaphroditic plants in the same population

ANDRODIOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: A sexual system in which males and hermaphrodites coexist in a population

TRIOECIOUS
type: Class
subclass of: PlantSexualSystem
definition: Having males, females, and hermaphrodites in the same population

AUTOSOMAL_DOMINANT
type: Class
title: Autosomal dominant inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes in which a trait manifests in heterozygotes.

AUTOSOMAL_RECESSIVE
type: Class
title: Autosomal recessive inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes in which a trait manifests in individuals with two pathogenic alleles.

BLUE
type: Class
title: Blue irides
subclass of: EyeColorEnum
definition: Blue eyes
hex range: 4169E1-87CEEB
prevalence: 8-10% worldwide

HETEROCHROMIA
type: Class
title: Heterochromia iridis
subclass of: EyeColorEnum
definition: Different colored eyes
note: complete or sectoral heterochromia

X_LINKED_RECESSIVE
type: Class
title: X-linked recessive inheritance
subclass of: HP_0001417
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for recessive traits related to a gene encoded on the X chromosome.

X_LINKED_DOMINANT
type: Class
title: X-linked dominant inheritance
subclass of: HP_0001417
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for dominant traits related to a gene encoded on the X chromosome.

MITOCHONDRIAL
type: Class
title: Mitochondrial inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for traits related to a gene encoded on the mitochondrial genome. Maternally inherited.

Y_LINKED
type: Class
title: Y-linked inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance that is observed for traits related to a gene encoded on the Y chromosome.

GRAY
type: Class
title: Premature graying of hair
subclass of: HairColorEnum
definition: Gray hair
hex range: 808080-C0C0C0

BLONDE
type: Class
title: Fair hair
subclass of: HairColorEnum
definition: Blonde/blond hair
hex range: FAF0BE-FFF8DC

RED
type: Class
title: Red hair
subclass of: HairColorEnum
definition: Red hair
hex range: 922724-FF4500
prevalence: 1-2% worldwide

CONGENITAL_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Present at birth
period: At birth

LATE_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: After 60 years
period: >60 years

INFANTILE_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Between 28 days and 1 year
period: 28 days to 1 year

MIDDLE_AGE_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Between 40 years and 60 years
period: 40-60 years

JUVENILE_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Between 5 years and 16 years
period: 5-16 years

NEONATAL_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Within first 28 days of life
period: 0-28 days

GRAY
type: Class
title: Iris hypopigmentation
subclass of: EyeColorEnum
definition: Gray eyes
hex range: 778899-C0C0C0
prevalence: <1% worldwide

POLYGENIC
type: Class
title: Polygenic inheritance
subclass of: HP_0001426
subclass of: ModeOfInheritance
definition: A mode of inheritance that depends on a mixture of major and minor genetic determinants possibly together with environmental factors.

OLIGOGENIC
type: Class
title: Oligogenic inheritance
subclass of: HP_0001426
subclass of: ModeOfInheritance
definition: A type of multifactorial inheritance governed by the simultaneous action of a few gene loci (typically three).

DIGENIC
type: Class
title: Digenic inheritance
subclass of: HP_0001426
subclass of: ModeOfInheritance
definition: A type of multifactorial inheritance governed by the simultaneous action of two gene loci.

WHITE
type: Class
title: White hair
subclass of: HairColorEnum
definition: White hair
hex: FFFFFF

EMBRYONAL_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: During embryonic period (0-8 weeks)
period: 0-8 weeks gestation

FETAL_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: During fetal period (8 weeks to birth)
period: 8 weeks to birth

YOUNG_ADULT_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Between 16 years and 40 years
period: 16-40 years

CHILDHOOD_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Between 1 year and 16 years
period: 1-16 years

MILD
type: Class
title: Mild symptoms, minimal impact
subclass of: SymptomSeverityEnum
grade: 1
impact: minimal daily activity limitation

MODERATE
type: Class
title: Moderate symptoms, some limitation
subclass of: SymptomSeverityEnum
grade: 2
impact: some daily activity limitation

SEVERE
type: Class
title: Severe symptoms, significant limitation
subclass of: SymptomSeverityEnum
grade: 3
impact: significant daily activity limitation

BILATERAL
type: Class
subclass of: LateralityEnum
definition: Both sides
note: Affecting both left and right

UNILATERAL
type: Class
subclass of: LateralityEnum
definition: One side (unspecified which)
note: Affecting only one side

RIGHT
type: Class
subclass of: LateralityEnum
definition: Right side
anatomical term: dexter

LEFT
type: Class
subclass of: LateralityEnum
definition: Left side
anatomical term: sinister

ANTENATAL_ONSET
type: Class
subclass of: OnsetTimingEnum
definition: Before birth (prenatal)
period: Before birth

SEMIDOMINANT
type: Class
title: Semidominant inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance for traits that can manifest in both monoallelic and biallelic states, with similar or differing phenotype severity.

PSEUDOAUTOSOMAL_DOMINANT
type: Class
title: Pseudoautosomal dominant inheritance
subclass of: HP_0034339
subclass of: ModeOfInheritance
definition: A type of pseudoautosomal inheritance that is dominant.

PSEUDOAUTOSOMAL_RECESSIVE
type: Class
title: Pseudoautosomal recessive inheritance
subclass of: HP_0034339
subclass of: ModeOfInheritance
definition: A type of pseudoautosomal inheritance that is recessive.

MENDELIAN
type: Class
title: Mendelian inheritance
subclass of: ModeOfInheritance
definition: A mode of inheritance of diseases whose pathophysiology can be traced back to deleterious variants in a single gene.

EMBRYONIC_STAGE
type: Class
title: embryonic stage
subclass of: HumanDevelopmentalStage
definition: Prenatal stage that starts with fertilization and ends with a fully formed embryo, before undergoing last development during the fetal stage. Up to 8 weeks post-fertilization.

ZYGOTE_STAGE
type: Class
title: Carnegie stage 01
subclass of: HumanDevelopmentalStage
definition: Embryonic stage defined by a fertilized oocyte and presence of pronuclei. Starts at day 1 post-fertilization.

CLEAVAGE_STAGE
type: Class
title: Carnegie stage 02
subclass of: HumanDevelopmentalStage
definition: Embryonic stage during which cell division occurs with reduction in cytoplasmic volume, and formation of inner and outer cell mass. 2-8 cells. Usually starts between day 2-3 post-fertilization.

BLASTOCYST_STAGE
type: Class
title: Carnegie stage 03
subclass of: HumanDevelopmentalStage
definition: Blastula stage with the loss of the zona pellucida and the definition of a free blastocyst. Usually starts between day 4-5 post-fertilization.

GASTRULA_STAGE
type: Class
title: gastrula stage
subclass of: HumanDevelopmentalStage
definition: Embryonic stage defined by a complex and coordinated series of cellular movements that occurs at the end of cleavage.

NEURULA_STAGE
type: Class
title: neurula stage
subclass of: HumanDevelopmentalStage
definition: Embryonic stage defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This stage starts the emergence of the central nervous system.

ORGANOGENESIS_STAGE
type: Class
title: organogenesis stage
subclass of: HumanDevelopmentalStage
definition: Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism.

FETAL_STAGE
type: Class
title: fetal stage
subclass of: HumanDevelopmentalStage
definition: Prenatal stage that starts with the fully formed embryo and ends at birth. Generally from 8 weeks post-fertilization until birth.

PRENATAL_STAGE
type: Class
title: prenatal stage
subclass of: HumanDevelopmentalStage
definition: Prenatal stage that starts with fertilization and ends at birth. Encompasses both embryonic and fetal stages.

MORULA_STAGE
type: Class
title: morula stage
subclass of: HumanDevelopmentalStage
definition: The later part of Carnegie stage 02 when the cells have coalesced into a mass but the blastocystic cavity has not formed.

AGED_STAGE
type: Class
title: late adult stage
subclass of: HumanDevelopmentalStage
definition: Late adult stage that refers to an individual who is over 60 and starts to have some age-related impairments. Often subdivided into young-old (60-79) and old-old (80+).

ADULT_STAGE
type: Class
title: adult stage
subclass of: HumanDevelopmentalStage
definition: Human developmental stage that refers to a sexually mature human. Starts at approximately 15 years according to HPO definitions.

INFANT_STAGE
type: Class
title: infant stage
subclass of: HumanDevelopmentalStage
definition: Immature stage that refers to an infant who is over 28 days and is under 12 months old.

NEONATAL_STAGE
type: Class
title: newborn stage (0-28 days)
subclass of: HumanDevelopmentalStage
definition: Immature stage that refers to a human newborn within the first 28 days of life.

TODDLER_STAGE
type: Class
title: child stage (1-4 yo)
subclass of: HumanDevelopmentalStage
definition: Human stage that refers to a child who is over 12 months and under 5 years old. Often divided into early toddler (1-2 years) and late toddler (2-3 years).

ADOLESCENT_STAGE
type: Class
title: 15-19 year-old
subclass of: HumanDevelopmentalStage
definition: A young adult stage that refers to an individual who is over 15 and under 20 years old. Period of transition from childhood to adulthood.

CHILD_STAGE
type: Class
title: juvenile stage (5-14 yo)
subclass of: HumanDevelopmentalStage
definition: Pediatric stage that refers to a human who is over 5 and under 15 years old. Covers elementary and middle school ages.

POSTNATAL_STAGE
type: Class
title: postnatal stage
subclass of: HumanDevelopmentalStage
definition: Human developmental stage that covers the whole of human life post birth.

TITLE
type: Class
title: document title
subclass of: ManuscriptSection
order: 1

ABSTRACT
type: Class
subclass of: ManuscriptSection
definition: Abstract
order: 3
typical length: 150-300 words

INTRODUCTION
type: Class
title: introduction to a publication about an investigation
subclass of: ManuscriptSection
alternative label: Background
definition: Introduction/Background
order: 5

METHODS
type: Class
title: methods section
subclass of: ManuscriptSection
alternative label: Experimental
alternative label: Materials and Methods
alternative label: Methodology
definition: Methods/Materials and Methods
order: 7

RESULTS
type: Class
title: results section
subclass of: ManuscriptSection
alternative label: Findings
order: 8

DISCUSSION
type: Class
title: discussion section of a publication about an investigation
subclass of: ManuscriptSection
order: 9

REFERENCES
type: Class
title: references section
subclass of: ManuscriptSection
alternative label: Bibliography
alternative label: Literature Cited
alternative label: Works Cited
definition: References/Bibliography
order: 12

AUTHORS
type: Class
title: author list
subclass of: ManuscriptSection
definition: Authors and affiliations
order: 2

AUTHOR_CONTRIBUTIONS
type: Class
title: author contributions section
subclass of: ManuscriptSection
alternative label: CRediT statement
definition: Author contributions
order: 1.13e+01

ACKNOWLEDGMENTS
type: Class
title: acknowledgements section
subclass of: ManuscriptSection
alternative label: Acknowledgements
definition: Acknowledgments
order: 11

ABBREVIATIONS
type: Class
title: abbreviations section
subclass of: ManuscriptSection
definition: List of abbreviations
placement: front matter

LAY_SUMMARY
type: Class
title: author summary section
subclass of: ManuscriptSection
definition: Lay summary/Plain language summary
audience: general public
order: 3.7e+00

CONCLUSIONS
type: Class
title: conclusion section
subclass of: ManuscriptSection
alternative label: Conclusion
definition: Conclusions
order: 10

CONFLICT_OF_INTEREST
type: Class
title: conflict of interest section
subclass of: ManuscriptSection
alternative label: Competing Interests
alternative label: Declaration of Interests
definition: Conflict of interest statement
order: 1.14e+01

ETHICS_STATEMENT
type: Class
title: ethical approval section
subclass of: ManuscriptSection
definition: Ethics approval statement
order: 1.16e+01

FUNDING
type: Class
title: funding source declaration section
subclass of: ManuscriptSection
alternative label: Financial Support
alternative label: Grant Information
definition: Funding information
order: 1.15e+01

FUTURE_DIRECTIONS
type: Class
title: future directions section
subclass of: ManuscriptSection
definition: Future directions/Future work
often part of: Discussion or Conclusions

KEYWORDS
type: Class
title: keywords section
subclass of: ManuscriptSection
order: 4

LIMITATIONS
type: Class
title: study limitations section
subclass of: ManuscriptSection
definition: Limitations section
often part of: Discussion

LITERATURE_REVIEW
type: Class
title: related work section
subclass of: ManuscriptSection
definition: Literature review
optional: true
order: 6

GRAPHICAL_ABSTRACT
type: Class
subclass of: ManuscriptSection
definition: Graphical abstract
format: visual
order: 3.6e+00

CONTEMPT
type: Class
title: Contempt
subclass of: ExtendedEmotionEnum
definition: Feeling that something is worthless

LOVE
type: Class
title: Love
subclass of: ExtendedEmotionEnum
definition: Feeling of deep affection

ANTICIPATION
type: Class
title: Erwartung
subclass of: ExtendedEmotionEnum
alternative label: expectant
alternative label: expectation
definition: Feeling of excitement about something that will happen

TRUST
type: Class
title: Trust
subclass of: ExtendedEmotionEnum
definition: Feeling of confidence in someone or something

MICROAEROPHILIC
type: Class
title: microaerophilic
subclass of: RelToOxygenEnum
definition: Organism that requires oxygen at lower concentrations than atmospheric

METAGENOME
type: Class
title: Mims
subclass of: ContigCollectionType
definition: Sequences assembled from DNA of mixed community.

SAG
type: Class
title: Misag
subclass of: ContigCollectionType
alternative label: Single Amplified Genome
definition: Sequences assembled from DNA of single cell.

MAG
type: Class
title: Mimag
subclass of: ContigCollectionType
alternative label: Metagenome-Assembled Genome
definition: Sequences assembled from DNA of mixed community and binned. MAGs are likely to represent a single taxonomic origin. See checkm2 scores for quality assessment.

VIRUS
type: Class
title: Miuvig
subclass of: ContigCollectionType
definition: Sequences assembled from uncultivated virus genome (DNA/RNA).

COIMMUNOPRECIPITATION
type: Class
subclass of: InteractionDetectionMethod
definition: Using antibody to capture bait and its ligands

CROSS_LINKING
type: Class
subclass of: InteractionDetectionMethod
alternative label: cross-linking study
definition: Chemical cross-linking of interacting proteins

ELECTRON_MICROSCOPY
type: Class
subclass of: InteractionDetectionMethod
definition: EM for structural determination

FLUORESCENCE_RESONANCE_ENERGY_TRANSFER
type: Class
subclass of: InteractionDetectionMethod
alternative label: fluorescent resonance energy transfer
definition: FRET for detecting proximity between molecules

NMR
type: Class
subclass of: InteractionDetectionMethod
alternative label: nuclear magnetic resonance
definition: Nuclear magnetic resonance spectroscopy

NUCLEIC_ACID_SEQUENCING
type: Class
subclass of: ParticipantIdentificationMethod
alternative label: nucleotide sequence identification
definition: DNA/RNA sequencing

PULL_DOWN
type: Class
subclass of: InteractionDetectionMethod
definition: Affinity capture using immobilized bait

SEQUENCE_TAG_IDENTIFICATION
type: Class
subclass of: ParticipantIdentificationMethod
definition: Using affinity tags

SURFACE_PLASMON_RESONANCE
type: Class
subclass of: InteractionDetectionMethod
definition: SPR for real-time binding analysis

WESTERN_BLOT
type: Class
subclass of: ParticipantIdentificationMethod
definition: Antibody-based detection

X_RAY_CRYSTALLOGRAPHY
type: Class
subclass of: InteractionDetectionMethod
definition: Crystal structure determination

BINDING_SITE
type: Class
subclass of: FeatureType
alternative label: binding-associated region
definition: Region involved in binding

MUTATION
type: Class
subclass of: FeatureType
definition: Sequence alteration

POST_TRANSLATIONAL_MODIFICATION
type: Class
subclass of: FeatureType
alternative label: acetylated residue
definition: PTM site

PHOSPHORYLATION_SITE
type: Class
subclass of: FeatureType
alternative label: phosphorylated residue
definition: Phosphorylated residue

ACETYLATION_REACTION
type: Class
subclass of: InteractionType
definition: Acetyltransferase-substrate relationship

CLEAVAGE_REACTION
type: Class
subclass of: InteractionType
definition: Protease-substrate relationship

GENETIC_INTERACTION
type: Class
subclass of: InteractionType
alternative label: genetic interaction (sensu unexpected)
definition: Genetic epistatic relationship

METHYLATION_REACTION
type: Class
subclass of: InteractionType
definition: Methyltransferase-substrate relationship

PHOSPHORYLATION_REACTION
type: Class
subclass of: InteractionType
definition: Kinase-substrate phosphorylation

UBIQUITINATION_REACTION
type: Class
subclass of: InteractionType
definition: Ubiquitin ligase-substrate relationship

GENE
type: Class
subclass of: InteractorType
definition: Gene locus

PROTEIN_COMPLEX
type: Class
subclass of: InteractorType
alternative label: complex
definition: Multi-protein assembly

NUCLEIC_ACID
type: Class
subclass of: InteractorType
definition: DNA or RNA

DNA
type: Class
subclass of: InteractorType
alternative label: deoxyribonucleic acid
definition: Deoxyribonucleic acid

RNA
type: Class
subclass of: InteractorType
alternative label: ribonucleic acid
definition: Ribonucleic acid

PROTEIN
type: Class
subclass of: InteractorType
definition: Polypeptide molecule

PEPTIDE
type: Class
subclass of: InteractorType
definition: Short polypeptide

SMALL_MOLECULE
type: Class
subclass of: InteractorType
definition: Small chemical compound

BIOPOLYMER
type: Class
subclass of: InteractorType
definition: Biological polymer

PREDETERMINED
type: Class
subclass of: ParticipantIdentificationMethod
alternative label: predetermined participant
definition: Known from experimental design

COLOCALIZATION
type: Class
subclass of: InteractionType
definition: Coincident occurrence in subcellular location

DIRECT_INTERACTION
type: Class
subclass of: InteractionType
definition: Direct physical contact between molecules

ENZYMATIC_REACTION
type: Class
subclass of: InteractionType
definition: Enzyme-substrate relationship

NECESSARY_BINDING_REGION
type: Class
subclass of: FeatureType
definition: Required for binding

SUFFICIENT_BINDING_REGION
type: Class
subclass of: FeatureType
definition: Sufficient for binding

BAIT
type: Class
subclass of: ExperimentalRole
definition: Molecule used to capture interacting partners

NEUTRAL_COMPONENT
type: Class
subclass of: ExperimentalRole
definition: Participant with no specific role

PREY
type: Class
subclass of: ExperimentalRole
definition: Molecule captured by the bait

ENZYME
type: Class
subclass of: ExperimentalRole
definition: Catalytically active participant

ENZYME_TARGET
type: Class
subclass of: ExperimentalRole
definition: Target of enzymatic activity

SELF
type: Class
subclass of: ExperimentalRole
definition: Self-interaction participant

OVEREXPRESSION
type: Class
subclass of: ExperimentalPreparation
alternative label: over expressed level
definition: Above physiological levels

TAG
type: Class
subclass of: FeatureType
definition: Affinity or epitope tag

INHIBITOR
type: Class
subclass of: ExperimentalRole
definition: Inhibitor of the interaction

AUTHOR_CONFIDENCE
type: Class
subclass of: ConfidenceScore
definition: Author-provided confidence

TANDEM_AFFINITY_PURIFICATION
type: Class
subclass of: InteractionDetectionMethod
definition: TAP tagging for protein complex purification

ANTIBODY_DETECTION
type: Class
subclass of: ParticipantIdentificationMethod
alternative label: antibody array
definition: Direct antibody recognition

COFACTOR
type: Class
subclass of: ExperimentalRole
definition: Required cofactor for interaction

ANCILLARY
type: Class
subclass of: ExperimentalRole
definition: Supporting but not directly interacting

KNOCKOUT
type: Class
subclass of: ExperimentalPreparation
alternative label: knock out
definition: Gene deletion

BIMOLECULAR_FLUORESCENCE_COMPLEMENTATION
type: Class
subclass of: InteractionDetectionMethod
definition: BiFC split fluorescent protein assay

PROXIMITY_LIGATION_ASSAY
type: Class
subclass of: InteractionDetectionMethod
definition: PLA for detecting protein proximity

STIMULATOR
type: Class
subclass of: ExperimentalRole
definition: Enhancer of the interaction

PUTATIVE_SELF
type: Class
subclass of: ExperimentalRole
definition: Potentially self-interacting

POLYSACCHARIDE
type: Class
subclass of: InteractorType
definition: Carbohydrate polymer

ASSOCIATION
type: Class
subclass of: InteractionType
definition: May form one or more physical complexes

PHYSICAL_ASSOCIATION
type: Class
subclass of: InteractionType
definition: Molecules within the same physical complex

COMPETITOR
type: Class
subclass of: ExperimentalRole
definition: Competitive inhibitor

SELF_INTERACTION
type: Class
subclass of: InteractionType
definition: Intra-molecular interaction

FUNCTIONAL_ASSOCIATION
type: Class
subclass of: InteractionType
definition: Functional modulation without direct contact

CRYO_ET
type: Class
title: electron tomography
subclass of: StructuralBiologyTechnique
definition: Cryo-electron tomography
aliases: cryoET, electron cryo-tomography
resolution range: 20-100 Å typical

MAMMALIAN_TWO_HYBRID
type: Class
subclass of: InteractionDetectionMethod
alternative label: mammalian membrane two hybrid
definition: Two-hybrid in mammalian cells

BODY_SIZE_MEASUREMENT
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: body size trait measurement
definition: Body size trait measurement

ROTAROD_TEST
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: rotarod performance test
definition: Rotarod motor coordination test

OPEN_FIELD_TEST
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Open field locomotor test

ELEVATED_PLUS_MAZE
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: elevated plus maze test
definition: Elevated plus maze anxiety test

PIPETTING
type: Class
title: pipette method
subclass of: LiquidHandlingOperationEnum
definition: A procedure or technique by which the size of the three dimensional space occupied by a liquid substance is ascertained using a pipette

CROSSLINKING
type: Class
title: crosslinked residues
subclass of: ProteinModificationType
definition: Crosslinking modification

ACETYLATION
type: Class
title: monoacetylated residue
subclass of: ProteinModificationType
definition: Acetylation modification

METHYLATION
type: Class
title: monomethylated residue
subclass of: ProteinModificationType
definition: Methylation modification

HYDROXYLATION
type: Class
title: hydroxylated residue
subclass of: ProteinModificationType
definition: Hydroxylation modification

PHOSPHORYLATION
type: Class
title: phosphorylated residue
subclass of: ProteinModificationType
definition: Phosphorylation modification

GLYCOSYLATION
type: Class
title: complex glycosylation
subclass of: ProteinModificationType
definition: Glycosylation modification

METAL_COORDINATION
type: Class
title: iron-sulfur cluster containing modification
subclass of: ProteinModificationType
definition: Metal coordination modification
examples: zinc finger, iron-sulfur cluster binding

SUMOYLATION
type: Class
title: sumoylated lysine
subclass of: ProteinModificationType
definition: SUMOylation modification

UBIQUITINATION
type: Class
title: ubiquitination signature tetrapeptidyl lysine
subclass of: ProteinModificationType
definition: Ubiquitination modification

ADDITION
type: Class
title: addition reaction
subclass of: ReactionTypeEnum
definition: Addition to multiple bond
subtypes: electrophilic, nucleophilic, radical

ELIMINATION
type: Class
title: elimination reaction
subclass of: ReactionTypeEnum
definition: Removal of atoms/groups forming double bond
subtypes: E1, E2, E1cB

SUBSTITUTION
type: Class
title: substitution reaction
subclass of: ReactionTypeEnum
definition: Replacement of one group by another
subtypes: SN1, SN2, SNAr

EXTERNAL_STANDARD
type: Class
title: external standard role
subclass of: AnalyticalControlType
definition: Reference standard used as external reference point

INTERNAL_STANDARD
type: Class
title: internal standard role
subclass of: AnalyticalControlType
definition: Known amount of standard added to analytical sample

LONG_TERM_REFERENCE
type: Class
title: long term reference role
subclass of: AnalyticalControlType
definition: Stable reference for cross-batch comparisons

NEGATIVE_CONTROL
type: Class
title: negative control role
subclass of: AnalyticalControlType
definition: Control providing baseline/no signal reference

POSITIVE_CONTROL
type: Class
title: positive control role
subclass of: AnalyticalControlType
definition: Control providing known positive signal

METABOLITE_QUANTITATION_HPLC
type: Class
title: metabolite quantitation using high performance liquid chromatography
subclass of: MetabolomicsAssayType
definition: Metabolite quantitation using HPLC

TARGETED_METABOLITE_PROFILING
type: Class
title: targeted metabolite profiling
subclass of: MetabolomicsAssayType
definition: Assay targeting specific known metabolites

UNTARGETED_METABOLITE_PROFILING
type: Class
title: untargeted metabolite profiling
subclass of: MetabolomicsAssayType
definition: Assay profiling all detectable metabolites

ACETYLATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of acetyl groups

TRIFLUOROACETYLATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of trifluoroacetyl groups

ALKYLATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of alkyl groups

METHYLATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of methyl groups

OXIMATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of oxime groups

SILYLATION
type: Class
subclass of: DerivatizationMethod
definition: Addition of silyl groups for improved volatility

GAS_CHROMATOGRAPHY
type: Class
subclass of: ChromatographyType
definition: Gas chromatography

HIGH_PERFORMANCE_LIQUID_CHROMATOGRAPHY
type: Class
subclass of: ChromatographyType
definition: High performance liquid chromatography

CONTINUOUS
type: Class
title: continuous fermentation cell culture
subclass of: FermentationModeEnum
definition: Continuous fermentation (chemostat)
operation: Continuous feed and harvest
steady state: true

WELL_96
type: Class
title: 96-well microplate
subclass of: MicroplateFormatEnum
definition: Microplate with 96 wells arranged in 8 rows of 12 columns with 9mm well-to-well spacing
standard: ANSI/SLAS 4-2004
well spacing: 9mm

COATED
type: Class
title: coated microplate
subclass of: PlateCoatingEnum
definition: A microplate whose surface has been treated, for instance by covalently attaching proteins to favor cell growth

UNCOATED
type: Class
title: uncoated microplate
subclass of: PlateCoatingEnum
definition: A microplate whose surface has not received any treatment and is uniquely made of polymer

BATCH
type: Class
title: batch cell culture
subclass of: FermentationModeEnum
definition: Batch fermentation
duration: Fixed time period
operation: All nutrients added at start

SCIEX
type: Class
title: SCIEX instrument model
subclass of: MassSpectrometerVendor
definition: SCIEX (formerly Applied Biosystems)

BRUKER_DALTONICS
type: Class
title: Bruker Daltonics instrument model
subclass of: MassSpectrometerVendor
definition: Bruker Daltonics

SHIMADZU
type: Class
title: Shimadzu instrument model
subclass of: MassSpectrometerVendor
definition: Shimadzu Corporation

WATERS
type: Class
title: Waters instrument model
subclass of: MassSpectrometerVendor
definition: Waters Corporation

THERMO_FISHER_SCIENTIFIC
type: Class
title: Thermo Fisher Scientific instrument model
subclass of: MassSpectrometerVendor
definition: Thermo Fisher Scientific

AGILENT
type: Class
title: Agilent instrument model
subclass of: MassSpectrometerVendor
definition: Agilent Technologies

WATERS_RAW
type: Class
title: Waters raw format
subclass of: MassSpectrometerFileFormat
definition: Waters raw format

WIFF
type: Class
title: ABI WIFF format
subclass of: MassSpectrometerFileFormat
definition: ABI WIFF format

THERMO_RAW
type: Class
title: Thermo RAW format
subclass of: MassSpectrometerFileFormat
definition: Thermo RAW format

MZDATA
type: Class
title: PSI mzData format
subclass of: MassSpectrometerFileFormat
definition: PSI mzData format

PKL
type: Class
title: Micromass PKL format
subclass of: MassSpectrometerFileFormat
definition: Micromass PKL format

MZXML
type: Class
title: ISB mzXML format
subclass of: MassSpectrometerFileFormat
definition: ISB mzXML format

MZML
type: Class
title: mzML format
subclass of: MassSpectrometerFileFormat
definition: mzML format - PSI standard for mass spectrometry data

DTA
type: Class
title: DTA format
subclass of: MassSpectrometerFileFormat
definition: DTA format

BRUKER_BAF
type: Class
title: Bruker BAF format
subclass of: MassSpectrometerFileFormat
definition: Bruker BAF format

MGF
type: Class
title: Mascot MGF format
subclass of: MassSpectrometerFileFormat
definition: Mascot Generic Format

MS2
type: Class
title: MS2 format
subclass of: MassSpectrometerFileFormat
definition: MS2 format

LECO
type: Class
title: LECO instrument model
subclass of: MassSpectrometerVendor
definition: LECO Corporation

MZ5
type: Class
title: mz5 format
subclass of: MassSpectrometerFileFormat
definition: mz5 format

FIRST_AUTHOR
type: Class
subclass of: ResearchRole
definition: First/lead author

UIMF
type: Class
title: UIMF format
subclass of: MassSpectrometerFileFormat
definition: UIMF format

BRUKER_TDF
type: Class
title: Bruker TDF format
subclass of: MassSpectrometerFileFormat
definition: Bruker TDF format

MZMLB
type: Class
title: mzMLb format
subclass of: MassSpectrometerFileFormat
definition: mzMLb format

BRUKER_TSF
type: Class
title: Bruker TSF format
subclass of: MassSpectrometerFileFormat
definition: Bruker TSF format

BLASTOCYST_STAGE
type: Class
title: Theiler stage 05
subclass of: MouseDevelopmentalStage
definition: Embryonic blastula stage defined by a zona free blastocyst (zona pellucida absent). Embryonic age 4 dpc.

GASTRULA_STAGE
type: Class
title: gastrula stage
subclass of: MouseDevelopmentalStage
definition: Embryonic stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage.

NEURULA_STAGE
type: Class
title: Theiler stage 11
subclass of: MouseDevelopmentalStage
definition: Embryonic stage called presomite stage and defined by the formation of the neural plate. This stage starts the emergence of the central nervous system at embryonic age 7.5 dpc.

ORGANOGENESIS_STAGE
type: Class
title: organogenesis stage
subclass of: MouseDevelopmentalStage
definition: Embryonic stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism.

E9_5
type: Class
title: Theiler stage 16
subclass of: MouseDevelopmentalStage
definition: Embryonic day 9.5 - organogenesis stage with visible hind limb buds. Between Theiler stages 15 and 16.

E14_5
type: Class
title: Theiler stage 22
subclass of: MouseDevelopmentalStage
definition: Embryonic day 14.5 - late organogenesis with clearly visible fingers and long bones of the limbs present.

P0_NEWBORN
type: Class
title: Theiler stage 27
subclass of: MouseDevelopmentalStage
definition: Stage that refers to the newborn mouse, aged E19-20, P0. Used for postnatal days 0 through 3.

AGED_12_MONTHS
type: Class
title: middle aged stage
subclass of: MouseDevelopmentalStage
definition: Middle aged stage for mice over 10 and under 18 months old. Shows progressive age-related changes.

P21_WEANING
type: Class
title: 2-week-old stage
subclass of: MouseDevelopmentalStage
definition: Weaning stage at approximately 21-22 days old. Transition from nursing to independent feeding.

P42_JUVENILE
type: Class
title: 6-week-old stage
subclass of: MouseDevelopmentalStage
definition: Prime adult stage at 6 weeks (42 days) old. Commonly considered the milestone for sexual maturity.

P56_ADULT
type: Class
title: 8-week-old stage
subclass of: MouseDevelopmentalStage
definition: Adult stage at 8 weeks (56 days) old. Fully mature adult mouse.

PHAGE_LAMBDA
type: Class
title: Lambdavirus lambda
subclass of: NCBITaxon_10239
subclass of: CommonOrganismTaxaEnum
definition: Escherichia phage lambda

INFLUENZA_A
type: Class
title: Influenza A virus
subclass of: NCBITaxon_10239
subclass of: CommonOrganismTaxaEnum
definition: Influenza A virus

HIV1
type: Class
title: Human immunodeficiency virus 1
subclass of: NCBITaxon_10239
subclass of: CommonOrganismTaxaEnum
definition: Human immunodeficiency virus 1

S_AUREUS
type: Class
title: Staphylococcus aureus
subclass of: NCBITaxon 1239
subclass of: CommonOrganismTaxaEnum
definition: Staphylococcus aureus

S_PNEUMONIAE
type: Class
title: Streptococcus pneumoniae
subclass of: NCBITaxon 1239
subclass of: CommonOrganismTaxaEnum
definition: Streptococcus pneumoniae

B_SUBTILIS
type: Class
title: Bacillus subtilis
subclass of: NCBITaxon 1239
subclass of: CommonOrganismTaxaEnum
definition: Bacillus subtilis

A_NIDULANS
type: Class
title: Aspergillus nidulans
subclass of: NCBITaxon 4890
subclass of: CommonOrganismTaxaEnum
definition: Aspergillus nidulans (filamentous fungus)

M_TUBERCULOSIS
type: Class
title: Mycobacterium tuberculosis
subclass of: NCBITaxon_201174
subclass of: CommonOrganismTaxaEnum
definition: Mycobacterium tuberculosis

LEPTOSPIRILLUM_FERROOXIDANS
type: Class
subclass of: BioleachOrganism
definition: Iron oxidizing bacterium

H_PYLORI
type: Class
title: Helicobacter pylori
subclass of: NCBITaxon 1224
subclass of: CommonOrganismTaxaEnum
definition: Helicobacter pylori

M_JANNASCHII
type: Class
title: Methanocaldococcus jannaschii
subclass of: NCBITaxon_28890
subclass of: CommonOrganismTaxaEnum
definition: Methanocaldococcus jannaschii

H_SALINARUM
type: Class
title: Halobacterium salinarum
subclass of: NCBITaxon_28890
subclass of: CommonOrganismTaxaEnum
definition: Halobacterium salinarum

SARS_COV_2
type: Class
title: Severe acute respiratory syndrome coronavirus 2
subclass of: NCBITaxon_10239
subclass of: CommonOrganismTaxaEnum
definition: Severe acute respiratory syndrome coronavirus 2

P_AERUGINOSA
type: Class
title: Pseudomonas aeruginosa
subclass of: NCBITaxon 1236
subclass of: CommonOrganismTaxaEnum
definition: Pseudomonas aeruginosa

PUFFERFISH
type: Class
title: Takifugu rubripes
subclass of: NCBITaxon 7898
subclass of: CommonOrganismTaxaEnum
definition: Takifugu rubripes (torafugu)

ANIMALIA
type: Class
title: Metazoa
subclass of: BiologicalKingdom
definition: Animal kingdom

RICE
type: Class
title: Oryza sativa
subclass of: NCBITaxon 3398
subclass of: CommonOrganismTaxaEnum
definition: Oryza sativa (rice)

S_POMBE
type: Class
title: Schizosaccharomyces pombe
subclass of: NCBITaxon 4890
subclass of: CommonOrganismTaxaEnum
definition: Schizosaccharomyces pombe (fission yeast)

ASPERGILLUS_NIGER
type: Class
subclass of: BioleachOrganism
definition: Organic acid producing fungus

N_CRASSA
type: Class
title: Neurospora crassa
subclass of: NCBITaxon 4890
subclass of: CommonOrganismTaxaEnum
definition: Neurospora crassa (red bread mold)

C_ALBICANS
type: Class
title: Candida albicans
subclass of: NCBITaxon 4890
subclass of: CommonOrganismTaxaEnum
definition: Candida albicans (pathogenic yeast)

T_BRUCEI
type: Class
title: Trypanosoma brucei
subclass of: NCBITaxon 2759
subclass of: CommonOrganismTaxaEnum
definition: Trypanosoma brucei

T_GONDII
type: Class
title: Toxoplasma gondii
subclass of: NCBITaxon 5794
subclass of: CommonOrganismTaxaEnum
definition: Toxoplasma gondii

P_FALCIPARUM
type: Class
title: Plasmodium falciparum
subclass of: NCBITaxon 5794
subclass of: CommonOrganismTaxaEnum
definition: Plasmodium falciparum (malaria parasite)

TETRAHYMENA
type: Class
title: Tetrahymena thermophila
subclass of: NCBITaxon 2759
subclass of: CommonOrganismTaxaEnum
definition: Tetrahymena thermophila

ACIDITHIOBACILLUS_FERROOXIDANS
type: Class
subclass of: BioleachOrganism
definition: Iron and sulfur oxidizing bacterium

UNFAVORABLE
type: Class
subclass of: DrugResponseEnum
definition: Unfavorable response to treatment
note: Worse than expected response

SQUARE_PLANAR
type: Class
title: Square Planar 1 Molecular Geometry
subclass of: CoordinationGeometry
definition: Square planar coordination geometry (4 ligands in plane)
coordination number: 4

TETRAHEDRAL
type: Class
title: tetrahedral molecular geometry
subclass of: CoordinationGeometry
definition: Tetrahedral coordination geometry (4 ligands, 109.5° angles)
coordination number: 4

OCTAHEDRAL
type: Class
title: Octahedral 12 Molecular Geometry
subclass of: CoordinationGeometry
definition: Octahedral coordination geometry (6 ligands)
coordination number: 6

COMPLETED
type: Class
title: Treatment Completed as Prescribed
subclass of: RegimenStatusEnum
definition: Treatment finished as planned

DIFFUSION_WEIGHTED
type: Class
title: Diffusion-weighted contrast
subclass of: MRIContrastTypeEnum
alternative label: Diffusion Weighted Imaging
definition: Image contrast based on water diffusion
sensitivity: molecular motion
typical use: stroke, tumor cellularity

TALEN
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: TALENs
definition: Transcription Activator-Like Effector Nucleases
mechanism: DNA cleavage

ZINC_FINGER_NUCLEASE
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: ZFN
definition: Zinc finger nucleases for gene editing
mechanism: DNA cleavage

SHRNA
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: shRNA
definition: Short hairpin RNA for stable gene silencing
delivery: viral transduction
duration: stable

ASL
type: Class
title: Arterial spin labeling
subclass of: MRIModalityEnum
alternative label: Arterial Spin Labeling Magnetic Resonance Imaging
definition: Perfusion imaging using magnetically labeled blood
advantage: no contrast agent required
contrast mechanism: arterial blood labeling
typical use: cerebral blood flow measurement

FUNCTIONAL_CONNECTIVITY
type: Class
title: Functional connectivity MRI
subclass of: MRIModalityEnum
alternative label: Functional Connectivity Magnetic Resonance Imaging
definition: Analysis of temporal correlations between brain regions
analysis type: connectivity mapping
metric: correlation coefficients
typical use: network analysis

STRUCTURAL_T1
type: Class
title: T1-weighted structural MRI
subclass of: MRIModalityEnum
alternative label: High Field Strength Magnetic Resonance Imaging
definition: High-resolution anatomical imaging with T1 contrast
contrast mechanism: T1 relaxation
tissue contrast: good gray/white matter contrast
typical use: anatomical reference, volumetric analysis

STRUCTURAL_T2
type: Class
title: T2-weighted structural MRI
subclass of: MRIModalityEnum
alternative label: Low Field Strength Magnetic Resonance Imaging
definition: Structural imaging with T2 contrast
contrast mechanism: T2 relaxation
tissue contrast: good fluid contrast
typical use: pathology detection, CSF visualization

PERFUSION_DCE
type: Class
title: Dynamic contrast-enhanced perfusion
subclass of: MRIModalityEnum
alternative label: Multiparametric Magnetic Resonance Imaging
definition: Perfusion imaging with pharmacokinetic modeling
analysis: pharmacokinetic modeling
contrast mechanism: contrast enhancement kinetics
typical use: blood-brain barrier permeability

PERFUSION_DSC
type: Class
title: Dynamic susceptibility contrast perfusion
subclass of: MRIModalityEnum
alternative label: Secretin-Enhanced Magnetic Resonance Imaging
definition: Perfusion imaging using contrast agent bolus
contrast mechanism: contrast agent dynamics
requires: gadolinium contrast
typical use: cerebral blood flow, blood volume

UV_SPEC
type: Class
subclass of: SpecimenQualityObservationMethodEnum
alternative label: Spectrophotometry
definition: UV-Vis spectrophotometry measuring absorbance across UV and visible ranges

MPRAGE
type: Class
title: Magnetization prepared rapid gradient echo
subclass of: MRISequenceTypeEnum
alternative label: Magnetization-Prepared Rapid Gradient Echo MRI
definition: T1-weighted 3D sequence with preparation pulse
dimension: 3D
image type: T1-weighted
typical use: high-resolution anatomical imaging

IMPROVISED_NUCLEAR_DEVICE
type: Class
title: Improvised Nuclear Device
subclass of: NuclearThreatCategoryType
definition: A crude nuclear weapon constructed from diverted or stolen fissile material

RADIOLOGICAL_DISPERSAL_DEVICE
type: Class
title: Radiological Dispersal Device
subclass of: NuclearThreatCategoryType
definition: A device that disperses radioactive material using conventional explosives or other means

SWI
type: Class
title: Susceptibility-weighted imaging
subclass of: MRIModalityEnum
definition: High-resolution venography and iron detection
contrast mechanism: magnetic susceptibility
strength: high field preferred
typical use: venography, microbleeds, iron deposits

FRAUDULENT
type: Class
title: Fraudulently Obtained Product
subclass of: FraudDetectionEnum
alternative label: 1
alternative label: fraud
alternative label: invalid
definition: Fraudulent transaction or activity

PDX_TISSUE
type: Class
subclass of: SpecimenTypeEnum
alternative label: PDX tissue
alternative label: Patient Derived Xenograft
definition: Patient-derived xenograft tissue

HUMANIZED_MOUSE
type: Class
subclass of: XenograftModelEnum
alternative label: humanized mouse model
definition: Mouse engrafted with human immune cells
engraftment: human immune system

FAVORABLE
type: Class
title: Favorable Response
subclass of: DrugResponseEnum
definition: Favorable response to treatment
note: Better than expected response

BONE_MARROW
type: Class
subclass of: SpecimenTypeEnum
alternative label: Bone Marrow
definition: Bone marrow specimen

BLOOD
type: Class
subclass of: SpecimenTypeEnum
alternative label: Blood
definition: Whole blood specimen

UNSOLVED
type: Class
title: Clinical Interpretation
subclass of: InterpretationProgressEnum
definition: No diagnosis achieved
note: Molecular cause not identified

CELL
type: Class
subclass of: SampleType
definition: Whole cell sample

GRANULOCYTES
type: Class
subclass of: SourceMaterialTypeEnum
alternative label: Granulocyte
definition: Granulocyte cells

NOT_PROVIDED
type: Class
title: Not Available
subclass of: InsdcMissingValueEnum
definition: Information of an expected format was not given, a value may be given at the later stage
note: Using NCIT:C126101 (Not Available) as a general term for data not provided

CSF
type: Class
subclass of: SpecimenTypeEnum
alternative label: Cerebrospinal Fluid
alternative label: cerebrospinal fluid
definition: Cerebrospinal fluid specimen

TISSUE_EXPLANT
type: Class
subclass of: ModelSystemTypeEnum
definition: Tissue explant culture

cfDNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Circulating Cell-Free DNA
alternative label: cell-free DNA
definition: Cell-free DNA found in blood plasma

MIXED
type: Class
title: Hybrid
subclass of: ViralGenomeTypeEnum
definition: Mixed or hybrid viral genome type

MICROPLATE_WELL
type: Class
title: microplate well
subclass of: ContainerTypeEnum
definition: Any of the individual wells on a microwell plate

XENOGRAFT
type: Class
subclass of: TransplantationTypeEnum
alternative label: heterograft
alternative label: xenotransplant
definition: Transplantation of cells, tissues, or organs between animals of different species
donor recipient: different species
example: human tumor in mouse

LOW_GRADE_GLIOMA
type: Class
title: Low Grade Glioma
subclass of: PediatricOncologyDiagnosisCategory
definition: Indolent glial tumors including pilocytic astrocytoma and pediatric-type diffuse low-grade gliomas (MYB/MYBL1-altered, MAPK pathway-altered).
category: brain_tumor
grade: low
who classification: WHO CNS5

STOOL
type: Class
subclass of: SpecimenTypeEnum
alternative label: Feces
alternative label: fecal
definition: Stool/fecal specimen

URINE
type: Class
subclass of: SpecimenTypeEnum
alternative label: Urine
definition: Urine specimen

SERUM
type: Class
subclass of: SpecimenTypeEnum
alternative label: Serum
definition: Blood serum specimen

L1
type: Class
title: INRG Stage L1
subclass of: INRGSSStage
definition: Localized tumor not involving vital structures as defined by the list of image-defined risk factors and confined to one body compartment (neck, chest, abdomen, or pelvis).
idrfs present: false
localized: true

L2
type: Class
title: INRG Stage L2
subclass of: INRGSSStage
definition: Locoregional tumor with presence of one or more image-defined risk factors. The tumor has not spread far from where it started but has at least one IDRF.
idrfs present: true
localized: true

M
type: Class
title: INRG Stage M
subclass of: INRGSSStage
definition: Distant metastatic disease (except as defined for MS). The tumor has spread (metastasized) to distant parts of the body.
metastatic: true

MS
type: Class
title: INRG Stage MS
subclass of: INRGSSStage
alternative label: Stage 4S equivalent
definition: Metastatic disease in children younger than 18 months with metastases confined to skin, liver, and/or bone marrow (bone marrow involvement limited to <10% tumor cells). This stage has a favorable prognosis despite metastatic disease.
age restriction: <18 months
favorable prognosis: true
metastatic: true
special category: true

PLASMA
type: Class
subclass of: SpecimenTypeEnum
alternative label: Plasma
definition: Blood plasma specimen

BACTERIA
type: Class
subclass of: WaterContaminantEnum
definition: Bacterial contamination

NOT_COLLECTED
type: Class
title: Missing Data
subclass of: InsdcMissingValueEnum
definition: Information of an expected format was not given because it has never been collected
note: NCIT:C142610 represents Missing Data which encompasses data not collected

RECRUITING
type: Class
title: Open To Enrollment
subclass of: RecruitmentStatusEnum
definition: Currently recruiting participants

FFPE
type: Class
subclass of: SpecimenPreparationMethodEnum
alternative label: FFPE Tissue Block
alternative label: Formalin-fixed paraffin-embedded
alternative label: formalin-fixed, paraffin-embedded
definition: Formalin-fixed, paraffin-embedded tissue preservation
embedding: paraffin
fixative: formalin

KNOCKOUT_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: Gene knockout animal model

SSRNA_NEGATIVE
type: Class
title: Negative Sense ssRNA Virus
subclass of: NCIT C95939
subclass of: ViralGenomeTypeEnum
alternative label: (-)ssRNA
alternative label: Baltimore Group V
alternative label: Group V
definition: Negative-sense single-stranded RNA viral genome

SSRNA_RT
type: Class
title: Deltaretrovirus
subclass of: NCIT C95939
subclass of: ViralGenomeTypeEnum
alternative label: Baltimore Group VI
alternative label: Group VI
alternative label: Retroviruses
definition: Single-stranded RNA viruses that replicate through a DNA intermediate (retroviruses)

DSDNA_RT
type: Class
title: Other Virus Grouping
subclass of: NCIT C14348
subclass of: ViralGenomeTypeEnum
alternative label: Baltimore Group VII
alternative label: Group VII
alternative label: Pararetroviruses
definition: Double-stranded DNA viruses that replicate through a single-stranded RNA intermediate (pararetroviruses)

SSDNA
type: Class
title: Single Stranded DNA Virus
subclass of: CHEBI_16991
subclass of: ViralGenomeTypeEnum
alternative label: Baltimore Group II
alternative label: Group II
definition: Single-stranded DNA viral genome

SSRNA_POSITIVE
type: Class
title: Positive Sense ssRNA Virus
subclass of: NCIT C95939
subclass of: ViralGenomeTypeEnum
alternative label: (+)ssRNA
alternative label: Baltimore Group IV
alternative label: Group IV
definition: Positive-sense single-stranded RNA viral genome

CONJUGATE_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A vaccine created by covalently attaching an antigen to a carrier protein

HIGH
type: Class
title: High Risk Neuroblastoma
subclass of: NeuroblastomaRiskGroup
definition: High risk neuroblastoma with poor prognosis. Requires intensive multimodal therapy including high-dose chemotherapy with autologous stem cell rescue, surgery, radiation, and immunotherapy.
expected efs: <50%
mycn amplified: often

CORE_NEEDLE_BIOPSY
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: Needle Biopsy
definition: Sample obtained by core needle biopsy

LUMBAR_PUNCTURE
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: Lumbar Puncture
alternative label: spinal tap
definition: CSF sample obtained by lumbar puncture

SURGICAL_RESECTION
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: Surgical Procedure
definition: Tissue obtained during surgical resection

NOT_AT_ALL_CONFIDENT
type: Class
subclass of: NCITFivePointConfidenceScale
alternative label: Confidence 1
definition: A subjective score of 1 - Not at all confident.

SLIGHTLY_CONFIDENT
type: Class
subclass of: NCITFivePointConfidenceScale
alternative label: Confidence 2
definition: A subjective score of 2 - Slightly confident.

SOMEWHAT_CONFIDENT
type: Class
subclass of: NCITFivePointConfidenceScale
alternative label: Confidence 3
definition: A subjective score of 3 - Somewhat confident.

MODERATELY_CONFIDENT
type: Class
subclass of: NCITFivePointConfidenceScale
alternative label: Confidence 4
definition: A subjective score of 4 - Moderately confident.

VERY_CONFIDENT
type: Class
subclass of: NCITFivePointConfidenceScale
alternative label: Confidence 5
definition: A subjective score of 5 - Very confident.

FINE_NEEDLE_ASPIRATE
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: FNA
alternative label: Fine-Needle Aspiration
definition: Sample obtained by fine needle aspiration

GRADIENT_ECHO
type: Class
title: Gradient echo sequence
subclass of: MRISequenceTypeEnum
alternative label: Gradient Echo MRI
definition: Fast imaging sequence using gradient reversal
artifact sensitivity: susceptible to magnetic field inhomogeneity
speed: fast
typical use: T2*, functional imaging

PHASE_1
type: Class
title: Phase I Trial
subclass of: StudyPhaseEnum
definition: Initial safety and dosage studies
participants: 20-100

PHASE_2
type: Class
title: Phase II Trial
subclass of: StudyPhaseEnum
definition: Efficacy and side effects studies
participants: 100-300

PHASE_3
type: Class
title: Phase III Trial
subclass of: StudyPhaseEnum
definition: Efficacy comparison with standard treatment
participants: 300-3000

PHASE_4
type: Class
title: Phase IV Trial
subclass of: StudyPhaseEnum
definition: Post-marketing surveillance
note: After FDA approval

T2_STAR
type: Class
title: T2*-weighted contrast
subclass of: MRIContrastTypeEnum
alternative label: T2 (Observed)-Weighted Imaging
definition: Image contrast sensitive to magnetic susceptibility
sensitivity: blood, iron, air-tissue interfaces
typical use: functional imaging, venography

MAGNETIC_FIELD_STRENGTH
type: Class
title: Magnetic Field Strength
subclass of: FusionPlasmaParameterType
definition: Strength of the magnetic field used to confine the plasma

PHASE_1_2
type: Class
title: Phase II/III Trial
subclass of: StudyPhaseEnum
definition: Combined Phase 1 and Phase 2 trial

GENETIC_TEST
type: Class
title: DNA/RNA analysis
subclass of: DiagnosticTestTypeEnum
alternative label: Genetic Testing
types: karyotype, sequencing, PCR

HEALTH_INSURANCE_COVERAGE_STATUS
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Health Insurance
definition: Status of health insurance coverage

NEUROSCIENCE
type: Class
title: Neuroscience and Neuropsychiatric Research
subclass of: ResearchField
definition: Neuroscience

OLDER_ADULT
type: Class
title: Elderly
subclass of: AgeGroupEnum
definition: 65 years and older
aliases: Geriatric, Elderly, Senior
min age years: 65

BIOCHEMISTRY
type: Class
title: Biochemistry
subclass of: ResearchField

BIOMATERIAL
type: Class
title: Biomedical Material
subclass of: MaterialClassEnum
alternative label: Biomaterial
definition: Materials designed to interact with biological systems

BLACK_OR_AFRICAN_AMERICAN
type: Class
subclass of: RaceOMB1997Enum
definition: A person having origins in any of the black racial groups of Africa
related match: ExO_0000132
omb code: 2054-5

IODINE_131
type: Class
title: Iodine I-131
subclass of: RadionuclideEnum
definition: Radioactive iodine isotope from nuclear fission. Concentrates in thyroid gland. Used medically and released in nuclear accidents.
decay mode: beta
half life: 8.02 days
health concern: thyroid cancer
symbol: I-131

CHEMISTRY
type: Class
subclass of: ResearchField
definition: Chemistry

PEDIATRIC
type: Class
title: Child
subclass of: AgeGroupEnum
definition: 6 to 12 years (NINDS CDE definition)
max age years: 12
min age years: 6
ninds category: true

CORRESPONDING_AUTHOR
type: Class
title: Corresponding Author indicator
subclass of: ResearchRole

CRYOPRESERVED
type: Class
subclass of: SpecimenPreparationMethodEnum
alternative label: Cryopreservation
alternative label: Cryopreserved
definition: Specimen preserved by freezing with cryoprotectant
temperature: ultra-low

RESPONSIVE
type: Class
title: Responsive Disease
subclass of: DrugResponseEnum
definition: Responsive to treatment
note: Shows expected response

STARTED
type: Class
title: Treatment Ongoing
subclass of: RegimenStatusEnum
definition: Treatment initiated

RESISTANT
type: Class
title: Drug Resistance Process
subclass of: DrugResponseEnum
definition: Resistant to treatment
note: No response to treatment

ECOLOGY
type: Class
title: Ecology
subclass of: ResearchField
definition: Ecology and environmental science

ANTISENSE_OLIGONUCLEOTIDE
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: ASO
alternative label: antisense
definition: Antisense oligonucleotides for gene silencing
mechanism: RNase H activation or steric blocking

ENDOSCOPY
type: Class
title: Internal visualization
subclass of: DiagnosticTestTypeEnum
alternative label: Endoscopic Procedure
types: colonoscopy, gastroscopy, bronchoscopy

GENETICS
type: Class
subclass of: ResearchField
definition: Genetics and genomics

NEONATE
type: Class
title: Newborn
subclass of: AgeGroupEnum
definition: Birth to 28 days
max age days: 28

IMAGING_MRI
type: Class
title: Magnetic resonance imaging
subclass of: DiagnosticTestTypeEnum
alternative label: Magnetic Resonance Imaging
radiation: no

MEDICINE
type: Class
subclass of: ResearchField
definition: Medicine and health sciences

MEMBRANE_PROTEIN
type: Class
subclass of: SampleType
definition: Membrane-associated protein sample

MICROBIOLOGY
type: Class
title: Microbiology
subclass of: ResearchField

PATHOGENIC
type: Class
title: Pathogenic Variant
subclass of: ACMGPathogenicityEnum
definition: Pathogenic variant
abbreviation: P
clinical significance: Disease-causing

LIKELY_PATHOGENIC
type: Class
title: Likely Pathogenic Variant
subclass of: ACMGPathogenicityEnum
definition: Likely pathogenic variant
abbreviation: LP
probability: >90% certain

LIKELY_BENIGN
type: Class
title: Variant Likely Benign
subclass of: ACMGPathogenicityEnum
definition: Likely benign variant
abbreviation: LB
probability: >90% certain benign

BENIGN
type: Class
title: Variant Benign
subclass of: ACMGPathogenicityEnum
definition: Benign variant
abbreviation: B
clinical significance: Not disease-causing

RETROVIRAL
type: Class
subclass of: VectorTypeEnum
definition: Retroviral vector (gamma-retrovirus)
integration: integrating

IMAGING_PET
type: Class
title: Positron emission tomography
subclass of: DiagnosticTestTypeEnum
alternative label: Positron Emission Tomography
uses: radiotracer

PROTON_DENSITY
type: Class
title: Proton density weighted
subclass of: MRIContrastTypeEnum
alternative label: Proton Density MRI
definition: Image contrast based on hydrogen density
tissue contrast: proportional to water content
typical use: joint imaging, some brain pathology

TOBACCO_SMOKE
type: Class
title: Passive Smoke Exposure
subclass of: ExposureSourceEnum
definition: Active or passive tobacco smoke exposure

FOOD_INSECURITY
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Food Insecurity
definition: Limited or uncertain availability of nutritionally adequate and safe foods

IMAGING_CT
type: Class
title: Computed tomography scan
subclass of: DiagnosticTestTypeEnum
alternative label: Computed Tomography
radiation: yes

IMAGING_ULTRASOUND
type: Class
title: Ultrasound imaging
subclass of: DiagnosticTestTypeEnum
alternative label: Ultrasound Imaging
radiation: no

IMAGING_XRAY
type: Class
title: X-ray imaging
subclass of: DiagnosticTestTypeEnum
alternative label: X-Ray
radiation: yes

MRNA_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A vaccine based on mRNA that encodes the antigen of interest

CRE_RECOMBINASE
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: CRE Recombinase
alternative label: Cre-lox
definition: Cre-lox recombination system for conditional gene modification
mechanism: site-specific recombination
use: conditional knockout

HISPANIC_OR_LATINO
type: Class
subclass of: EthnicityOMB1997Enum
definition: A person of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin, regardless of race
related match: ExO_0000137
related match: ExO_0000138
related match: ExO_0000140
related match: ExO_0000141
related match: ExO_0000142
related match: ExO_0000145
related match: ExO_0000149
related match: ExO_0000150
related match: ExO_0000151
related match: ExO_0000155
omb code: 2135-2

PEPTIDE_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A vaccine based on synthetic peptides

EPI
type: Class
title: Echo planar imaging
subclass of: MRISequenceTypeEnum
definition: Ultrafast imaging sequence
speed: very fast
temporal resolution: subsecond
typical use: functional MRI, diffusion imaging

ADULT
type: Class
subclass of: AgeGroupEnum
definition: 25 to 64 years
max age years: 64
min age years: 25

SPHEROID
type: Class
subclass of: ModelSystemTypeEnum
definition: Three-dimensional cell aggregates

XO
type: Class
title: 45,XO Karyotype
subclass of: KaryotypicSexEnum
definition: Turner syndrome karyotype (45,X)
chromosome count: 45
condition: Turner syndrome

XYY
type: Class
title: 47,XYY Karyotype
subclass of: KaryotypicSexEnum
definition: Jacob's syndrome karyotype (47,XYY)
chromosome count: 47
condition: Jacob's syndrome

XXY
type: Class
title: 47,XXY Karyotype
subclass of: KaryotypicSexEnum
definition: Klinefelter syndrome karyotype (47,XXY)
chromosome count: 47
condition: Klinefelter syndrome

XXX
type: Class
title: 47,XXX Karyotype
subclass of: KaryotypicSexEnum
definition: Triple X syndrome karyotype (47,XXX)
chromosome count: 47
condition: Triple X syndrome

XXXY
type: Class
title: 48,XXXY Karyotype
subclass of: KaryotypicSexEnum
definition: XXXY syndrome karyotype (48,XXXY)
chromosome count: 48
condition: XXXY syndrome

XXXX
type: Class
title: 48,XXXX Karyotype
subclass of: KaryotypicSexEnum
definition: Tetrasomy X karyotype (48,XXXX)
chromosome count: 48
condition: Tetrasomy X

TASK_FMRI
type: Class
title: Task-based functional MRI
subclass of: MRIModalityEnum
alternative label: Task Functional Magnetic Resonance Imaging
definition: fMRI during specific cognitive or motor tasks
analysis: statistical parametric mapping
paradigm: stimulus-response
typical use: localization of brain functions

EMPLOYMENT_STATUS
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Employment Status
definition: Current employment situation and stability

BOLD_FMRI
type: Class
title: Blood oxygen level dependent fMRI
subclass of: MRIModalityEnum
alternative label: Functional Magnetic Resonance Imaging
definition: Functional MRI based on blood oxygenation changes
contrast mechanism: BOLD signal
temporal resolution: seconds
typical use: brain activation mapping

T1_WEIGHTED
type: Class
title: T1-weighted contrast
subclass of: MRIContrastTypeEnum
alternative label: T1-Weighted Magnetic Resonance Imaging
definition: Image contrast based on T1 relaxation times
tissue contrast: gray matter darker than white matter
typical use: anatomical structure

T2_WEIGHTED
type: Class
title: T2-weighted contrast
subclass of: MRIContrastTypeEnum
alternative label: T2-Weighted Magnetic Resonance Imaging
definition: Image contrast based on T2 relaxation times
tissue contrast: CSF bright, gray matter brighter than white
typical use: pathology detection

MOLECULAR_DYNAMICS
type: Class
title: Molecular Dynamics
subclass of: MaterialsSimulationType
definition: Simulation of atomic and molecular motion by numerically integrating equations of motion

TPM
type: Class
subclass of: ExpressionUnitEnum
alternative label: Transcript per million
definition: Transcripts per million - normalized for gene length and sequencing depth
formula: (reads/gene_length_kb) / sum(reads/gene_length_kb) * 1e6
normalization: length and depth
use: within and between sample comparisons

PARTIALLY_RESPONSIVE
type: Class
title: Stable Disease
subclass of: DrugResponseEnum
definition: Partial response to treatment
note: Some but not complete response

FULLY_VACCINATED
type: Class
subclass of: VaccinationStatusEnum
definition: A status indicating that an individual has received all the required vaccinations

PARTIALLY_VACCINATED
type: Class
subclass of: VaccinationStatusEnum
definition: A status indicating that an individual has received some of the required vaccinations

NOT_VACCINATED
type: Class
subclass of: VaccinationStatusEnum
definition: A status indicating that an individual has not received any of the required vaccinations

HIGH_THROUGHPUT_SCREENING
type: Class
title: High Throughput Screening
subclass of: LabAutomationWorkflowType
definition: Workflow for rapid parallel evaluation of many samples or conditions
related match: BAO_0010074
characteristic: massively parallel evaluation

DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: DNA Specimen
definition: Deoxyribonucleic acid

RNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: RNA Specimen
definition: Ribonucleic acid

FELLOWSHIP
type: Class
title: Fellowship Program
subclass of: FundingType
definition: Fellowship or scholarship

TRUFI
type: Class
title: True fast imaging with steady-state precession
subclass of: MRISequenceTypeEnum
alternative label: Constructive Interference In Steady State
definition: Balanced steady-state free precession sequence
contrast: mixed T1/T2
signal: high
typical use: cardiac imaging, fast scanning

RNAI
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: RNA interference
alternative label: RNAi
definition: RNA interference for post-transcriptional gene silencing
effect: knockdown
mechanism: mRNA degradation

ACTIONABLE
type: Class
title: Actionable Variation
subclass of: TherapeuticActionabilityEnum
definition: Finding has direct therapeutic implications
note: Can guide treatment selection

NOT_ACTIONABLE
type: Class
title: Non-Actionable Variation
subclass of: TherapeuticActionabilityEnum
definition: No current therapeutic implications
note: No treatment changes indicated

SOLVED
type: Class
title: Molecular Diagnosis
subclass of: InterpretationProgressEnum
definition: Diagnosis achieved/case solved
note: Molecular cause identified

NOT_YET_RECRUITING
type: Class
title: Not Yet Enrolling
subclass of: RecruitmentStatusEnum
definition: Study has not started recruiting participants

ENROLLING_BY_INVITATION
type: Class
subclass of: RecruitmentStatusEnum
definition: Enrolling participants by invitation only

ACTIVE_NOT_RECRUITING
type: Class
title: Study Active, Not Enrolling
subclass of: RecruitmentStatusEnum
definition: Study ongoing but not recruiting new participants

SUSPENDED
type: Class
title: Study Enrollment Suspended
subclass of: RecruitmentStatusEnum
definition: Study temporarily stopped

COMPLETED
type: Class
title: Procedure Completed
subclass of: InterpretationProgressEnum
definition: Analysis completed
note: May be solved or unsolved

SIRNA
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: siRNA
definition: Small interfering RNA for transient gene silencing
delivery: transfection
duration: transient

AUTOPSY
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: Autopsy
definition: Specimen obtained at autopsy

PERSON
type: Class
subclass of: ContributorType
definition: A person.

WEIGHT
type: Class
subclass of: SpecimenQuantityObservationTypeEnum
alternative label: Weight
definition: Current weight of the specimen

VOLUME
type: Class
subclass of: SpecimenQuantityObservationTypeEnum
alternative label: Volume
definition: Current volume of the specimen

IN_PROGRESS
type: Class
title: Progress
subclass of: InterpretationProgressEnum
definition: Analysis ongoing

ADOLESCENT
type: Class
subclass of: AgeGroupEnum
definition: 13 to 17 years
max age years: 17
min age years: 13

INFANT
type: Class
subclass of: AgeGroupEnum
definition: 29 days to less than 1 year
max age years: 1
min age days: 29

CHLORINE
type: Class
subclass of: WaterContaminantEnum
definition: Chlorine and chlorination byproducts

LYOPHILIZED
type: Class
subclass of: SpecimenPreparationMethodEnum
alternative label: Freeze-Drying
alternative label: freeze-dried
alternative label: lyophilization
definition: Freeze-dried specimen

INTRAMUSCULAR
type: Class
title: Into muscle
subclass of: DrugRouteEnum
alternative label: Intramuscular Route of Administration
abbreviation: IM
sites: deltoid, gluteus, vastus lateralis

LINEAR_ACCELERATOR
type: Class
title: Linear Accelerator
subclass of: ParticleAcceleratorType
definition: Linear accelerator (linac) that accelerates particles along a straight path

PARASITES
type: Class
title: Parasite
subclass of: WaterContaminantEnum
definition: Parasitic contamination

VENIPUNCTURE
type: Class
subclass of: SpecimenCollectionMethodEnum
alternative label: Phlebotomy
definition: Blood sample obtained by venipuncture

COBALT_60
type: Class
title: Cobalt Co-60
subclass of: RadioactiveContaminantType
definition: Cobalt-60, a gamma emitter with a half-life of approximately 5 years
decay mode: beta, gamma
half life: 5.27 years

VACCINATED
type: Class
subclass of: VaccinationStatusEnum
definition: A status indicating that an individual has received a vaccination

DSRNA
type: Class
title: Double Stranded RNA Virus
subclass of: CHEBI_33697
subclass of: ViralGenomeTypeEnum
alternative label: Baltimore Group III
alternative label: Group III
definition: Double-stranded RNA viral genome

ADENOCARCINOMA_NOS
type: Class
title: Adenocarcinoma
subclass of: NCIT C2916
subclass of: TumorMorphology
definition: Malignant glandular epithelial neoplasm. Cancer arising from glandular epithelium.
icdo code: 8140

IIc_BURKITT_LYMPHOMA
type: Class
title: Burkitt Lymphoma
subclass of: ICCC3Subgroup
definition: Burkitt lymphoma and Burkitt-like lymphoma.
icdo3 codes: 9687
main group: II

IN_SITU
type: Class
title: Carcinoma In Situ
subclass of: TumorBehavior
definition: Malignant cells confined to epithelium without invasion through basement membrane. Pre-invasive cancer.
icdo behavior: /2

SQUAMOUS_CELL_CARCINOMA
type: Class
title: Squamous Cell Carcinoma
subclass of: NCIT C2916
subclass of: TumorMorphology
definition: Malignant neoplasm arising from squamous epithelium. Common in skin, lung, esophagus, and cervix.
icdo code: 8070

TRANSITIONAL_CELL_CARCINOMA
type: Class
title: Transitional Cell Carcinoma
subclass of: NCIT C2916
subclass of: TumorMorphology
definition: Malignant neoplasm arising from transitional epithelium (urothelium). Most common in bladder and urinary tract.
icdo code: 8120

CRANIOPHARYNGIOMA
type: Class
title: Craniopharyngioma
subclass of: PediatricOncologyDiagnosisCategory
definition: Benign epithelial tumors arising from remnants of Rathke pouch, including adamantinomatous and papillary subtypes.
category: brain_tumor
who classification: WHO CNS5

INACTIVATED_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A preparation of killed microorganisms intended to prevent infectious disease

PLUTONIUM_239
type: Class
title: Plutonium-239
subclass of: RadionuclideEnum
definition: Transuranic element produced in nuclear reactors. Highly toxic alpha emitter with very long half-life.
decay mode: alpha
half life: 24100 years
source: nuclear reactors
symbol: Pu-239

ENDOCRINE_AND_NEUROENDOCRINE_TUMOR
type: Class
title: Endocrine Neoplasm
subclass of: PediatricOncologyDiagnosisCategory
definition: Tumors of endocrine glands and neuroendocrine cells, including thyroid carcinoma, adrenocortical carcinoma, pheochromocytoma, and paraganglioma.
category: solid_tumor

IXb_FIBROSARCOMAS
type: Class
title: Fibrosarcoma
subclass of: ICCC3Subgroup
definition: Fibrosarcoma, NOS; infantile fibrosarcoma; dermatofibrosarcoma; and malignant peripheral nerve sheath tumor.
icdo3 codes: 8810-8815, 8820-8823, 8830, 8832-8833, 9540, 9560-9561
main group: IX

BIOPHARMACEUTICAL
type: Class
title: Biological Agent
subclass of: BioproductCategoryType
definition: Pharmaceutical products derived from biological sources or manufactured using biotechnology
examples: recombinant proteins, monoclonal antibodies, vaccines

VIIb_HEPATIC_CARCINOMAS
type: Class
title: Hepatocellular Carcinoma
subclass of: ICCC3Subgroup
definition: Hepatocellular carcinoma, cholangiocarcinoma, and other hepatic carcinomas.
main group: VII

DRUG
type: Class
title: Drug allergy
subclass of: AllergyTypeEnum
alternative label: Hypersensitivity
examples: penicillin, sulfa drugs

LEIOMYOSARCOMA
type: Class
title: Leiomyosarcoma
subclass of: NCIT C9118
subclass of: TumorMorphology
definition: Malignant tumor arising from smooth muscle.
icdo code: 8890

CHRONIC_LYMPHOCYTIC_LEUKEMIA
type: Class
title: Chronic lymphocytic leukemia
subclass of: NCIT C3161
subclass of: TumorMorphology
definition: Chronic leukemia of mature B lymphocytes.
icdo code: 9823

CHRONIC_MYELOID_LEUKEMIA
type: Class
title: Chronic myeloid leukemia
subclass of: NCIT C3161
subclass of: TumorMorphology
definition: Chronic leukemia characterized by BCR-ABL1 fusion gene.
icdo code: 9875

LIPOSARCOMA
type: Class
title: Liposarcoma
subclass of: NCIT C9118
subclass of: TumorMorphology
definition: Malignant tumor arising from adipose tissue.
icdo code: 8850

MEDULLOBLASTOMA
type: Class
title: Medulloblastoma
subclass of: PediatricOncologyDiagnosisCategory
definition: Embryonal tumor of the cerebellum, classified by molecular subgroups (WNT-activated, SHH-activated, Group 3, Group 4) per WHO CNS5.
category: brain_tumor
who classification: WHO CNS5

MESOTHELIOMA
type: Class
title: Mesothelioma
subclass of: TumorMorphology
definition: Malignant tumor arising from mesothelial cells lining pleura, peritoneum, or pericardium. Strongly associated with asbestos exposure.
icdo code: 9050

Id_MYELODYSPLASTIC_OTHER_MYELOPROLIFERATIVE
type: Class
title: Myelodysplastic Syndrome
subclass of: ICCC3Subgroup
definition: Myelodysplastic syndrome, NOS; refractory anemia; refractory anemia with ringed sideroblasts; refractory anemia with excess blasts.
icdo3 codes: 9945, 9980, 9982-9983, 9985-9989
main group: I

VIa_NEPHROBLASTOMA
type: Class
title: Wilms Tumor
subclass of: ICCC3Subgroup
definition: Wilms tumor (nephroblastoma), clear cell sarcoma of kidney, rhabdoid tumor of kidney, and other nonepithelial renal tumors.
icdo3 codes: 8960, 8963-8964
main group: VI

IVb_OTHER_PERIPHERAL_NERVOUS
type: Class
title: Peripheral Nervous System Neoplasm
subclass of: ICCC3Subgroup
definition: Other peripheral nerve tumors including ganglioneuroma and peripheral nerve sheath tumors.
icdo3 codes: 9501-9504, 9520-9523
main group: IV

PLEURAL_EFFUSION
type: Class
subclass of: SourceMaterialTypeEnum
alternative label: Pleural Effusion
definition: Fluid from pleural effusion

XIe_SKIN_CARCINOMAS
type: Class
title: Skin Neoplasm
subclass of: ICCC3Subgroup
definition: Basal cell carcinoma, squamous cell carcinoma of skin, and other skin carcinomas.
main group: XI

CHOROID_PLEXUS_TUMOR
type: Class
title: Choroid Plexus Neoplasm
subclass of: PediatricOncologyDiagnosisCategory
definition: Neoplasms arising from the choroid plexus epithelium, including papilloma, atypical papilloma, and carcinoma.
category: brain_tumor
who classification: WHO CNS5

STRESS
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Stress
definition: Psychological stress affecting health and wellbeing

BENIGN
type: Class
title: Benign Neoplasm
subclass of: TumorBehavior
definition: Non-cancerous neoplasm that does not invade surrounding tissue or metastasize.
icdo behavior: /0

CHROMIUM
type: Class
subclass of: HeavyMetalEnum
definition: Chromium (Cr)

VIIa_HEPATOBLASTOMA
type: Class
title: Hepatoblastoma
subclass of: ICCC3Subgroup
definition: Hepatoblastoma.
icdo3 codes: 8970
main group: VII

ECG
type: Class
title: Electrocardiogram
subclass of: DiagnosticTestTypeEnum
alternative label: Electroencephalography
measures: heart electrical activity

RHABDOID_TUMOR
type: Class
title: Rhabdoid Tumor
subclass of: PediatricOncologyDiagnosisCategory
definition: Highly aggressive tumors characterized by SMARCB1 loss, occurring outside the CNS (extracranial rhabdoid tumor). Includes malignant rhabdoid tumor of kidney.
category: solid_tumor

OTIC
type: Class
title: Into the ear
subclass of: DrugRouteEnum
alternative label: Auricular Route of Administration
forms: drops

INHALATION
type: Class
title: By breathing in
subclass of: DrugRouteEnum
alternative label: Inhalation Route of Administration
devices: inhaler, nebulizer

EPIDURAL
type: Class
title: Into epidural space
subclass of: DrugRouteEnum
alternative label: Intraepidermal Route of Administration
use: anesthesia, analgesia

INTRATHECAL
type: Class
title: Into spinal fluid
subclass of: DrugRouteEnum
alternative label: Intraventricular Route of Administration
use: CNS drugs

RECTAL
type: Class
title: Into the rectum
subclass of: DrugRouteEnum
alternative label: Rectal Route of Administration
forms: suppository, enema

SUBCUTANEOUS
type: Class
title: Under the skin
subclass of: DrugRouteEnum
alternative label: Subcutaneous Route of Administration
abbreviation: SC, SubQ
absorption: slow

SUBLINGUAL
type: Class
title: Under the tongue
subclass of: DrugRouteEnum
alternative label: Sublingual Route of Administration
absorption: rapid

TOPICAL
type: Class
title: On the skin surface
subclass of: DrugRouteEnum
alternative label: Topical Route of Administration
forms: cream, ointment, gel

TRANSDERMAL
type: Class
title: Through the skin
subclass of: DrugRouteEnum
alternative label: Transdermal Route of Administration
forms: patch

TRANSPLACENTAL
type: Class
title: Transplacental Route of Administration
subclass of: ExposureRouteEnum
definition: Exposure through placental transfer
related match: ExO_0000159

DERMAL
type: Class
title: Cutaneous Route of Administration
subclass of: ExposureRouteEnum
definition: Exposure through skin contact

XIc_NASOPHARYNGEAL_CARCINOMAS
type: Class
title: Nasopharyngeal Carcinoma
subclass of: ICCC3Subgroup
definition: Nasopharyngeal carcinoma and related carcinomas.
main group: XI

SMALL_CELL_CARCINOMA
type: Class
title: Small Cell Neuroendocrine Carcinoma
subclass of: NCIT C2916
subclass of: TumorMorphology
definition: Highly malignant neuroendocrine carcinoma with small cells. Most common in lung.
icdo code: 8041

YOUNG_PEDIATRIC
type: Class
title: Pediatric
subclass of: AgeGroupEnum
definition: 0 to 5 years (NINDS CDE definition)
max age years: 5
min age years: 0
ninds category: true

MBA
type: Class
subclass of: AcademicDegree
alternative label: Master of Business Administration
definition: Master of Business Administration
level: graduate

MPH
type: Class
subclass of: AcademicDegree
alternative label: Master of Public Health
definition: Master of Public Health
level: graduate

DNA_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A vaccine using DNA to produce protein that promotes immune responses

AUTOGRAFT
type: Class
subclass of: TransplantationTypeEnum
alternative label: autologous transplant
alternative label: autotransplant
definition: Transplantation of tissue from one body location to another within the same individual
donor recipient: same individual
example: skin graft, autologous stem cell transplant

ISOGRAFT
type: Class
subclass of: TransplantationTypeEnum
alternative label: isogeneic transplant
alternative label: syngeneic transplant
definition: Transplantation of cells, tissues, or organs between genetically identical individuals (e.g., identical twins, inbred strains)
donor recipient: genetically identical
example: transplant between identical twins

CONCENTRATION
type: Class
subclass of: SpecimenQuantityObservationTypeEnum
alternative label: Concentration
definition: Concentration of extracted analyte in specimen

ORGANIZATION
type: Class
subclass of: ContributorType
alternative label: Institution
definition: An organization.

NATIVE_HAWAIIAN_OR_OTHER_PACIFIC_ISLANDER
type: Class
subclass of: RaceOMB1997Enum
definition: A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands
related match: ExO_0000144
related match: ExO_0000152
related match: ExO_0000154
related match: ExO_0000156
omb code: 2076-8

NOT_HISPANIC_OR_LATINO
type: Class
subclass of: EthnicityOMB1997Enum
definition: A person not of Hispanic or Latino origin
omb code: 2186-5

AMERICAN_INDIAN_OR_ALASKA_NATIVE
type: Class
subclass of: RaceOMB1997Enum
definition: A person having origins in any of the original peoples of North and South America (including Central America), and who maintains tribal affiliation or community attachment
related match: ExO_0000133
related match: ExO_0000134
omb code: 1002-5

ASIAN
type: Class
subclass of: RaceOMB1997Enum
definition: A person having origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent
related match: ExO_0000135
related match: ExO_0000136
related match: ExO_0000139
related match: ExO_0000143
related match: ExO_0000147
related match: ExO_0000148
related match: ExO_0000157
includes: Cambodia, China, India, Japan, Korea, Malaysia, Pakistan, Philippine Islands, Thailand, Vietnam
omb code: 2028-9

WHITE
type: Class
subclass of: RaceOMB1997Enum
definition: A person having origins in any of the original peoples of Europe, the Middle East, or North Africa
related match: ExO_0000158
omb code: 2106-3

DISCONTINUED_ADVERSE_EVENT
type: Class
title: Adverse Event
subclass of: RegimenStatusEnum
definition: Stopped due to adverse event
reason: Toxicity or side effects

CO_AUTHOR
type: Class
title: Author
subclass of: ResearchRole
definition: Co-author

MICROPLATE
type: Class
title: microplate
subclass of: ContainerTypeEnum
definition: A flat dish with multiple individual wells that are arrayed in a standardized number, size, and arrangement

Ic_CHRONIC_MYELOPROLIFERATIVE
type: Class
title: Myeloproliferative Neoplasm
subclass of: ICCC3Subgroup
definition: Chronic myeloid leukemia, NOS; juvenile myelomonocytic leukemia; and other chronic myeloproliferative diseases.
icdo3 codes: 9863, 9875-9876, 9945-9946, 9950, 9960-9964
main group: I

DIOXINS
type: Class
title: Dioxin Compound
subclass of: EndocrineDisruptorEnum
definition: Dioxins

FAIL
type: Class
title: Fail
subclass of: QualityControlEnum
alternative label: 0
alternative label: defective
alternative label: failed
alternative label: reject
definition: Item does not meet quality standards

CADMIUM
type: Class
subclass of: HeavyMetalEnum
definition: Cadmium (Cd)

XX
type: Class
title: XX Genotype
subclass of: KaryotypicSexEnum
definition: Female karyotype (46,XX)
chromosome count: 46
typical phenotypic sex: female

XY
type: Class
title: XY Genotype
subclass of: KaryotypicSexEnum
definition: Male karyotype (46,XY)
chromosome count: 46
typical phenotypic sex: male

GLIONEURONAL_AND_NEURONAL_TUMOR
type: Class
title: Glioneuronal and Neuronal Tumors
subclass of: PediatricOncologyDiagnosisCategory
definition: Tumors with neuronal differentiation including ganglioglioma, dysembryoplastic neuroepithelial tumor (DNET), and central neurocytoma.
category: brain_tumor
who classification: WHO CNS5

RECURRENT_TUMOR
type: Class
subclass of: SourceMaterialTypeEnum
alternative label: Recurrent Neoplasm
definition: Recurrent tumor tissue

HIGH_GRADE_GLIOMA
type: Class
title: Malignant Glioma
subclass of: PediatricOncologyDiagnosisCategory
definition: Aggressive glial tumors including pediatric-type diffuse high-grade gliomas (H3 K27-altered, H3 G34-mutant, and H3/IDH-wildtype), as well as glioblastoma.
category: brain_tumor
grade: high
who classification: WHO CNS5

DISCONTINUED_PATIENT_DECISION
type: Class
title: Consent Withdrawn
subclass of: RegimenStatusEnum
definition: Stopped by patient choice

PHASE_2_3
type: Class
title: Phase IIa Trial
subclass of: StudyPhaseEnum
definition: Combined Phase 2 and Phase 3 trial

TRANSFORMER
type: Class
title: Transformer Device
subclass of: GridComponentType
definition: Device that changes voltage levels between transmission and distribution systems

CNS_SARCOMA
type: Class
title: Central Nervous System Sarcoma
subclass of: PediatricOncologyDiagnosisCategory
definition: Sarcomas arising primarily in the central nervous system, including Ewing sarcoma and rhabdomyosarcoma of CNS.
category: brain_tumor

CO_INVESTIGATOR
type: Class
title: Co-Investigator
subclass of: ResearchRole

NOT_STARTED
type: Class
title: Device Evaluation Anticipated But Not Yet Begun
subclass of: RegimenStatusEnum
definition: Treatment not yet begun

MISSING
type: Class
title: missing
subclass of: InsdcMissingValueEnum
definition: Not stated explicitly or implied by any other means

ANNUAL
type: Class
subclass of: VaccinationPeriodicityEnum
definition: Vaccination occurring once per year

EARLY_PHASE_1
type: Class
title: Phase 0 Trial
subclass of: StudyPhaseEnum
definition: Exploratory trials before traditional Phase 1
aliases: Phase 0

IIIb_ASTROCYTOMAS
type: Class
title: Astrocytoma
subclass of: ICCC3Subgroup
definition: Pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, glioblastoma, and other astrocytic tumors.
icdo3 codes: 9380, 9384, 9400-9411, 9420, 9424
main group: III

COMPOSITE
type: Class
title: Composite
subclass of: MaterialClassEnum
definition: Materials made from two or more constituent materials

NANOMATERIAL
type: Class
title: Nanomaterial
subclass of: MaterialClassEnum
definition: Materials with at least one dimension in nanoscale (1-100 nm)

QUANTUM_DOT
type: Class
title: Quantum Dot
subclass of: QubitType
definition: Qubit using semiconductor quantum dot nanostructures

DTI
type: Class
title: Diffusion tensor imaging
subclass of: MRIModalityEnum
definition: Advanced diffusion imaging with directional information
contrast mechanism: directional diffusion
parameters: fractional anisotropy, mean diffusivity
typical use: white matter tractography

MERCURY
type: Class
subclass of: HeavyMetalEnum
definition: Mercury (Hg)

MORE_THAN_ONE_RACE
type: Class
title: Multiracial
subclass of: RaceOMB1997Enum
definition: Person identifies with more than one race category
note: Added after 1997 revision to allow multiple race reporting

RESTRICTED_ACCESS
type: Class
title: Data Not Releasable
subclass of: InsdcMissingValueEnum
definition: Information exists but cannot be released openly because of privacy concerns
note: NCIT:C67110 represents Data Not Releasable due to confidentiality

HIGH_SCHOOL_GRADUATE_GED
type: Class
subclass of: EducationalAttainmentEnum
alternative label: GED
alternative label: High School Completion
alternative label: high school diploma
definition: High school graduate or GED equivalent

MISSING_THIRD_PARTY_DATA
type: Class
title: Source Data Not Available
subclass of: InsdcMissingValueEnum
definition: Information has not been revealed by another party
note: NCIT:C67329 represents Source Data Not Available

DECONTAMINATION
type: Class
title: Decontamination
subclass of: DecommissioningPhaseType
definition: Removing radioactive contamination from surfaces, equipment, and structures

ATYPICAL_TERATOID_RHABDOID_TUMOR
type: Class
title: Atypical Teratoid/Rhabdoid Tumor
subclass of: PediatricOncologyDiagnosisCategory
definition: Highly malignant embryonal CNS tumor characterized by loss of SMARCB1 (INI1) or SMARCA4 expression. Predominantly occurs in young children.
category: brain_tumor
who classification: WHO CNS5

PRIMARY_CELLS
type: Class
subclass of: ModelSystemTypeEnum
definition: Primary cells directly from tissue

NUCLEIC_ACID
type: Class
title: Nucleic Acids
subclass of: SampleType
definition: Nucleic acid sample (DNA or RNA)

COMPLETED
type: Class
title: Completed Clinical Study
subclass of: RecruitmentStatusEnum
definition: Study has ended normally

TERMINATED
type: Class
title: Study Terminated
subclass of: RecruitmentStatusEnum
definition: Study stopped early and will not resume

WITHDRAWN
type: Class
title: Study Withdrawn
subclass of: RecruitmentStatusEnum
definition: Study withdrawn before enrollment

ANIMAL_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: In vivo animal model

ASSOCIATE_DEGREE
type: Class
subclass of: EducationalAttainmentEnum
alternative label: Associate of Science
definition: Associate degree (2-year college)

BENG
type: Class
subclass of: AcademicDegree
alternative label: Bachelor of Engineering
definition: Bachelor of Engineering
level: undergraduate

BFA
type: Class
subclass of: AcademicDegree
alternative label: Bachelor of Fine Arts
definition: Bachelor of Fine Arts
level: undergraduate

LLB
type: Class
subclass of: AcademicDegree
alternative label: Bachelor of Science in Law
definition: Bachelor of Laws
level: undergraduate

EDD
type: Class
subclass of: AcademicDegree
alternative label: Doctor of Education
definition: Doctor of Education
level: doctoral

JD
type: Class
subclass of: AcademicDegree
alternative label: Doctor of Law
definition: Juris Doctor
level: doctoral

LLM
type: Class
subclass of: AcademicDegree
alternative label: Master of Law
definition: Master of Laws
level: graduate

MA
type: Class
subclass of: AcademicDegree
alternative label: Master of Arts
definition: Master of Arts
level: graduate

MENG
type: Class
subclass of: AcademicDegree
alternative label: Master of Engineering
definition: Master of Engineering
level: graduate

MED
type: Class
subclass of: AcademicDegree
alternative label: Master of Education
definition: Master of Education
level: graduate

SCD
type: Class
subclass of: AcademicDegree
alternative label: Doctor of Science
definition: Doctor of Science
level: doctoral

PLASMID
type: Class
subclass of: VectorTypeEnum
definition: Plasmid DNA vector
delivery: transfection
duration: transient

ADENOVIRAL
type: Class
subclass of: VectorTypeEnum
definition: Adenoviral vector
integration: non-integrating

AAV
type: Class
subclass of: VectorTypeEnum
alternative label: adeno-associated virus
definition: Adeno-associated viral vector
integration: non-integrating (episomal)

BIOPOLYMER
type: Class
title: Biopolymer
subclass of: PolymerTypeEnum
definition: Polymer produced by living organisms

LENTIVIRAL
type: Class
subclass of: VectorTypeEnum
definition: Lentiviral vector
integration: integrating

XIb_THYROID_CARCINOMAS
type: Class
title: Malignant Thyroid Gland Neoplasm
subclass of: ICCC3Subgroup
definition: Papillary thyroid carcinoma, follicular thyroid carcinoma, and medullary thyroid carcinoma.
main group: XI

HIGH_SCHOOL_NO_DIPLOMA
type: Class
subclass of: EducationalAttainmentEnum
alternative label: Not High School Graduate
alternative label: some high school
definition: Some high school but no diploma

PASS
type: Class
title: Pass
subclass of: QualityControlEnum
alternative label: 1
alternative label: acceptable
alternative label: ok
alternative label: passed
definition: Item meets quality standards

MRNA
type: Class
subclass of: VectorTypeEnum
definition: mRNA delivery
duration: transient

FLAIR
type: Class
title: Fluid-attenuated inversion recovery
subclass of: MRIModalityEnum
definition: T2-weighted sequence with CSF signal suppressed
advantage: suppresses CSF signal
contrast mechanism: T2 with fluid suppression
typical use: lesion detection, periventricular pathology

COLLABORATOR
type: Class
title: Collaborator
subclass of: ResearchRole

BUFFY_COAT
type: Class
subclass of: SpecimenTypeEnum
alternative label: Buffy Coat
definition: Leukocyte-enriched blood fraction

STAGE_1
type: Class
title: INSS Stage 1
subclass of: INSSStage
definition: Localized tumor with complete gross excision, with or without microscopic residual disease; representative ipsilateral lymph nodes negative for tumor microscopically.
localized: true
resection: complete

STAGE_2A
type: Class
title: INSS Stage 2A
subclass of: INSSStage
definition: Localized tumor with incomplete gross excision; representative ipsilateral nonadherent lymph nodes negative for tumor microscopically.
localized: true
lymph nodes: negative
resection: incomplete

STAGE_2B
type: Class
title: INSS Stage 2B
subclass of: INSSStage
definition: Localized tumor with or without complete gross excision, with ipsilateral nonadherent lymph nodes positive for tumor. Enlarged contralateral lymph nodes must be negative microscopically.
localized: true
lymph nodes: ipsilateral_positive

STAGE_3
type: Class
title: INSS Stage 3
subclass of: INSSStage
definition: Unresectable unilateral tumor infiltrating across the midline, with or without regional lymph node involvement; or localized unilateral tumor with contralateral regional lymph node involvement; or midline tumor with bilateral extension by infiltration (unresectable) or by lymph node involvement.
crosses midline: true
localized: false

STAGE_4
type: Class
title: INSS Stage 4
subclass of: INSSStage
definition: Any primary tumor with dissemination to distant lymph nodes, bone, bone marrow, liver, skin, and/or other organs (except as defined for stage 4S).
metastatic: true

STAGE_4S
type: Class
title: INSS Stage 4S
subclass of: INSSStage
alternative label: Special stage 4
definition: Localized primary tumor (as defined for stage 1, 2A, or 2B) with dissemination limited to skin, liver, and/or bone marrow (limited to infants <1 year of age). Marrow involvement should be minimal (<10% of total nucleated cells).
age restriction: <12 months
favorable prognosis: true
metastatic: true
special category: true

DIFFUSE_LARGE_B_CELL_LYMPHOMA
type: Class
title: Diffuse large B-cell lymphoma
subclass of: NCIT C3211
subclass of: TumorMorphology
definition: Most common type of non-Hodgkin lymphoma.
icdo code: 9680

Xb_EXTRACRANIAL_EXTRAGONADAL_GERM_CELL
type: Class
title: Malignant Extragonadal Germ Cell Tumor
subclass of: ICCC3Subgroup
definition: Extracranial germ cell tumors not involving the gonads including sacrococcygeal, retroperitoneal, and mediastinal germ cell tumors.
main group: X

XXYY
type: Class
title: XXYY Syndrome
subclass of: KaryotypicSexEnum
definition: XXYY syndrome karyotype (48,XXYY)
chromosome count: 48
condition: XXYY syndrome

IXc_KAPOSI_SARCOMA
type: Class
title: Kaposi Sarcoma
subclass of: ICCC3Subgroup
definition: Kaposi sarcoma.
icdo3 codes: 9140
main group: IX

OTHER_SOLID_TUMOR
type: Class
title: Childhood Solid Neoplasm
subclass of: PediatricOncologyDiagnosisCategory
definition: Solid tumors not classified elsewhere, including hepatoblastoma, pleuropulmonary blastoma, nasopharyngeal carcinoma, melanoma, and carcinomas.
category: solid_tumor

YOUNG_ADULT
type: Class
subclass of: AgeGroupEnum
definition: 18 to 24 years
max age years: 24
min age years: 18

LYMPHOPROLIFERATIVE_DISEASE
type: Class
title: Lymphoproliferative Disorder
subclass of: PediatricOncologyDiagnosisCategory
definition: Disorders characterized by abnormal lymphocyte proliferation, including post-transplant lymphoproliferative disorder (PTLD) and hemophagocytic lymphohistiocytosis (HLH).
category: hematologic

XIa_ADRENOCORTICAL_CARCINOMAS
type: Class
title: Adrenal Cortical Carcinoma
subclass of: ICCC3Subgroup
definition: Adrenocortical carcinoma.
icdo3 codes: 8370
main group: XI

VIb_RENAL_CARCINOMAS
type: Class
title: Renal Cell Carcinoma
subclass of: ICCC3Subgroup
definition: Renal cell carcinoma and other renal carcinomas.
main group: VI

UNCERTAIN_SIGNIFICANCE
type: Class
title: Variant of Unknown Significance
subclass of: ACMGPathogenicityEnum
definition: Variant of uncertain significance
abbreviation: VUS
note: Insufficient evidence

WINTER
type: Class
subclass of: Season
definition: Winter season
astronomical start: ~Dec 21
months: Dec-Feb

SPRING
type: Class
subclass of: Season
definition: Spring season
astronomical start: ~Mar 20
months: Mar-May

SUMMER
type: Class
subclass of: Season
definition: Summer season
astronomical start: ~Jun 21
months: Jun-Aug

AUTUMN
type: Class
subclass of: Season
definition: Autumn/Fall season
aliases: Fall
astronomical start: ~Sep 22
months: Sep-Nov

CYCLOTRON
type: Class
title: Cyclotron
subclass of: ParticleAcceleratorType
definition: Circular accelerator using constant magnetic field and alternating electric field

MORPHOLINO
type: Class
subclass of: GenePerturbationMethodEnum
definition: Morpholino oligomers for gene knockdown
mechanism: steric blocking
use: developmental biology

DEFINITIVE
type: Class
subclass of: OBCSCertaintyLevel
alternative label: definitive certainty level
definition: Definitive certainty level - the highest degree of certainty.

HIGH
type: Class
subclass of: OBCSCertaintyLevel
alternative label: high certainty level
definition: High certainty level - strong confidence but not absolute.

INTERMEDIATE
type: Class
subclass of: OBCSCertaintyLevel
alternative label: intermediate certainty level
definition: Intermediate certainty level - moderate degree of certainty.

DERIVATION_FROM_SPECIMEN
type: Class
subclass of: SpecimenCreationActivityTypeEnum
alternative label: material processing
definition: Activity that derives a new specimen from an existing one

INCUBATOR
type: Class
title: incubator
subclass of: LaboratoryDeviceTypeEnum
definition: A device in which environmental conditions (light, photoperiod, temperature, humidity, etc.) can be controlled

PCR
type: Class
subclass of: CellBasedAssayEnum
alternative label: polymerase chain reaction
definition: Polymerase chain reaction

GENOTYPING
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Genotyping assay

SPIN_COLUMN
type: Class
title: spin column
subclass of: ContainerTypeEnum
definition: A chromatography column which is suitable for putting it into a centrifuge

COLLECTION_FROM_SOURCE
type: Class
subclass of: SpecimenCreationActivityTypeEnum
alternative label: specimen collection process
definition: Activity that collects an initial sample directly from a subject or source

ELISA
type: Class
subclass of: CellBasedAssayEnum
definition: Enzyme-linked immunosorbent assay

ROCHE_454_GS
type: Class
subclass of: SequencingPlatform
alternative label: 454 Genome Sequencer FLX
definition: Roche 454 Genome Sequencer
chemistry: pyrosequencing
manufacturer: Roche/454
read type: short
status: discontinued

WESTERN_BLOT
type: Class
subclass of: CellBasedAssayEnum
definition: Western blot analysis

CHIP_SEQ
type: Class
subclass of: SequencingAssayEnum
alternative label: ChIP-seq
definition: Chromatin immunoprecipitation sequencing

IMMUNOASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: General immunoassay

SEQUENCING_BY_LIGATION
type: Class
subclass of: SequencingChemistry
alternative label: DNA sequencing by ligation assay
definition: Sequencing by ligation (SOLiD)

SEQUENCING_BY_SYNTHESIS
type: Class
subclass of: SequencingChemistry
alternative label: DNA sequencing by synthesis assay
definition: Sequencing by synthesis (Illumina)

BISULFITE_SEQUENCING
type: Class
subclass of: SequencingAssayEnum
alternative label: BS-seq
definition: Bisulfite sequencing for DNA methylation

QPCR
type: Class
subclass of: CellBasedAssayEnum
alternative label: quantitative PCR
definition: Quantitative PCR

FLOW_CYTOMETRY
type: Class
subclass of: CellBasedAssayEnum
definition: Flow cytometry analysis

MICROPLATE_READER
type: Class
title: microplate reader
subclass of: LaboratoryDeviceTypeEnum
definition: A measurement device that detects biological, chemical or physical events of samples in microtiter plates

ELISA_MICROPLATE_READER
type: Class
title: ELISA microplate reader
subclass of: LaboratoryDeviceTypeEnum
definition: A microplate reader that is used for enzyme-linked immunosorbent assays (ELISA)

INCUBATOR_SHAKER
type: Class
title: incubator shaker
subclass of: LaboratoryDeviceTypeEnum
definition: An incubating device that provides shaking motion for biomedical applications (e.g., cell cultures)

MULTIMODE_MICROPLATE_READER
type: Class
title: multimode microplate reader
subclass of: LaboratoryDeviceTypeEnum
definition: A microplate reader that can detect multiple types of absorbance, luminescence or fluorescence

LIQUID_EXTRACTION_ROBOT
type: Class
title: liquid extraction robot
subclass of: LaboratoryDeviceTypeEnum
definition: A liquid handling device that provides automatic liquid extraction

MICROCENTRIFUGE
type: Class
title: microcentrifuge
subclass of: LaboratoryDeviceTypeEnum
definition: A type of centrifuge that is designed for small tubes (0.2 ml to 2.0 ml), has a compact design, and has a small footprint

MICROPLATE_WASHER
type: Class
title: microplate washer
subclass of: LaboratoryDeviceTypeEnum
definition: A device that is used to wash immunoassays in microwell strips and plates with professional accuracy

ELISA_MICROPLATE_WASHER
type: Class
title: ELISA microplate washer
subclass of: LaboratoryDeviceTypeEnum
definition: A microplate washer that is used for enzyme-linked immunosorbent assays (ELISA)

MULTICHANNEL_PIPETTE
type: Class
title: multichannel pipette
subclass of: LaboratoryDeviceTypeEnum
definition: A pipetting system that has a plurality of tip fittings and is used for multi-well plate applications

CHEMICAL_MUTAGENESIS
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: EMS mutagenesis
alternative label: ENU mutagenesis
definition: Chemical mutagen-induced mutagenesis
mechanism: base modification

HOMOLOGOUS_RECOMBINATION
type: Class
subclass of: GeneKnockoutMethodEnum
definition: Traditional homologous recombination-based knockout
use: ES cell targeting

TRANSPOSON_MUTAGENESIS
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: transposon insertion
definition: Transposon-mediated insertional mutagenesis
mechanism: random insertion

SNP_ARRAY
type: Class
subclass of: SequencingAssayEnum
definition: SNP genotyping array

RNA_SEQ
type: Class
subclass of: SequencingAssayEnum
alternative label: RNA-seq
definition: RNA sequencing to profile transcriptome

BRDU_PROLIFERATION
type: Class
subclass of: CellBasedAssayEnum
alternative label: BrdU proliferation assay
definition: BrdU incorporation proliferation assay

METHYLATION_ARRAY
type: Class
subclass of: SequencingAssayEnum
definition: DNA methylation array

RNA_ARRAY
type: Class
subclass of: SequencingAssayEnum
definition: RNA expression array

FUNCTIONAL_MRI
type: Class
subclass of: ImagingAssayEnum
alternative label: fMRI
definition: Functional magnetic resonance imaging

IN_VIVO_BIOLUMINESCENCE
type: Class
subclass of: ImagingAssayEnum
definition: In vivo bioluminescence imaging

QUESTIONNAIRE
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Questionnaire-based assessment

POSITRON_EMISSION_TOMOGRAPHY
type: Class
subclass of: ImagingAssayEnum
alternative label: PET
definition: Positron emission tomography

ELECTROPORATION
type: Class
subclass of: VectorTypeEnum
definition: Electroporation-based delivery
method: physical

RPPA
type: Class
subclass of: MassSpectrometryAssayEnum
definition: Reverse Phase Protein Array

IMMUNOHISTOCHEMISTRY
type: Class
subclass of: ImagingAssayEnum
alternative label: IHC
definition: Immunohistochemistry staining

ILLUMINA_HISEQ_2000
type: Class
subclass of: SequencingPlatform
definition: Illumina HiSeq 2000
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

ILLUMINA_HISEQ_2500
type: Class
subclass of: SequencingPlatform
definition: Illumina HiSeq 2500
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

ILLUMINA_MISEQ
type: Class
subclass of: SequencingPlatform
definition: Illumina MiSeq
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

PACBIO_RS_II
type: Class
subclass of: SequencingPlatform
definition: PacBio RS II
chemistry: single molecule real time
manufacturer: Pacific Biosciences
read type: long

ILLUMINA_NEXTSEQ_500
type: Class
subclass of: SequencingPlatform
definition: Illumina NextSeq 500
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

ATAC_SEQ
type: Class
subclass of: SequencingAssayEnum
alternative label: ATAC-seq
definition: Assay for Transposase-Accessible Chromatin sequencing

HI_C
type: Class
subclass of: SequencingAssayEnum
alternative label: Hi-C
definition: High-throughput chromosome conformation capture

ILLUMINA_HISEQ_3000
type: Class
subclass of: SequencingPlatform
definition: Illumina HiSeq 3000
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

ILLUMINA_HISEQ_4000
type: Class
subclass of: SequencingPlatform
definition: Illumina HiSeq 4000
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

MIRNA_SEQ
type: Class
subclass of: SequencingAssayEnum
alternative label: miRNA-seq
definition: MicroRNA sequencing

WHOLE_GENOME_SEQUENCING
type: Class
subclass of: SequencingAssayEnum
alternative label: WGS
definition: Whole genome sequencing

WHOLE_EXOME_SEQUENCING
type: Class
subclass of: SequencingAssayEnum
alternative label: WES
definition: Whole exome sequencing

ILLUMINA_HISEQ_X
type: Class
subclass of: SequencingPlatform
alternative label: Illumina HiSeq X Ten
definition: Illumina HiSeq X
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

WHOLE_CELL_PATCH_CLAMP
type: Class
subclass of: CellBasedAssayEnum
definition: Whole-cell patch clamp recording

MULTI_ELECTRODE_ARRAY
type: Class
subclass of: CellBasedAssayEnum
definition: Multi-electrode array recording

OVEREXPRESSION
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: transgene expression
definition: Transgene overexpression
effect: gain of function

CASE
type: Class
title: case role in case-control study
subclass of: CaseOrControlEnum

CONTROL
type: Class
title: control role in case-control study
subclass of: CaseOrControlEnum

NEUROPSYCHOLOGICAL_ASSESSMENT
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Neuropsychological testing

ILLUMINA_NOVASEQ_6000
type: Class
subclass of: SequencingPlatform
definition: Illumina NovaSeq 6000
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

SINGLE_CELL_RNA_SEQ
type: Class
subclass of: SequencingAssayEnum
alternative label: scRNA-seq
definition: Single-cell RNA sequencing

PACBIO_SEQUEL
type: Class
subclass of: SequencingPlatform
definition: PacBio Sequel
chemistry: single molecule real time
manufacturer: Pacific Biosciences
read type: long

PACBIO_SEQUEL_II
type: Class
subclass of: SequencingPlatform
definition: PacBio Sequel II
chemistry: single molecule real time
manufacturer: Pacific Biosciences
read type: long

NANOPORE_MINION
type: Class
subclass of: SequencingPlatform
alternative label: Oxford Nanopore MinION
definition: Oxford Nanopore MinION
chemistry: nanopore sequencing
manufacturer: Oxford Nanopore Technologies
read type: long

NANOPORE_GRIDION
type: Class
subclass of: SequencingPlatform
alternative label: Oxford Nanopore GridION Mk1
definition: Oxford Nanopore GridION
chemistry: nanopore sequencing
manufacturer: Oxford Nanopore Technologies
read type: long

NANOPORE_PROMETHION
type: Class
subclass of: SequencingPlatform
alternative label: Oxford Nanopore PromethION
definition: Oxford Nanopore PromethION
chemistry: nanopore sequencing
manufacturer: Oxford Nanopore Technologies
read type: long

CONVENTIONAL_MRI
type: Class
subclass of: ImagingAssayEnum
definition: Conventional magnetic resonance imaging

MAGNETIC_RESONANCE_ANGIOGRAPHY
type: Class
subclass of: ImagingAssayEnum
alternative label: MRA
definition: Magnetic resonance angiography

FISH
type: Class
subclass of: ImagingAssayEnum
alternative label: Fluorescence In Situ Hybridization
definition: Fluorescence In Situ Hybridization

IMMUNOFLUORESCENCE
type: Class
subclass of: ImagingAssayEnum
definition: Immunofluorescence staining and imaging

ILLUMINA_NEXTSEQ_550
type: Class
subclass of: SequencingPlatform
definition: Illumina NextSeq 550
chemistry: sequencing by synthesis
manufacturer: Illumina
read type: short

CENTRIFUGE
type: Class
title: centrifuge
subclass of: LaboratoryDeviceTypeEnum
definition: A device with a rapidly rotating container that applies centrifugal force to its contents

HISTOLOGY
type: Class
subclass of: ImagingAssayEnum
definition: Histological examination

GREEN
type: Class
subclass of: PlantLeafColorEnum
definition: Green leaves (healthy/summer)
hex range: 228B22-90EE90
season: spring/summer

RED
type: Class
subclass of: PlantLeafColorEnum
definition: Red leaves (autumn or certain species)
hex: DC143C
season: autumn

YELLOW
type: Class
subclass of: PlantLeafColorEnum
definition: Yellow leaves (autumn or chlorosis)
hex: FFD700
season: autumn

OPAQUE
type: Class
title: Opaque
subclass of: OpticalPropertyEnum
definition: Does not allow light to pass through

TRANSPARENT
type: Class
title: Transparent
subclass of: OpticalPropertyEnum
definition: Allows light to pass through with minimal scattering

PERMEABILITY
type: Class
subclass of: SubsurfacePropertyType
definition: The ability of a porous material to allow fluids to pass through it

POROSITY
type: Class
subclass of: SubsurfacePropertyType
definition: The fraction of void space in a rock or sediment relative to its total volume

ELASTIC
type: Class
title: Elastic
subclass of: MechanicalBehaviorEnum
definition: Returns to original shape after stress removal

PLASTIC
type: Class
title: inelastic
subclass of: MechanicalBehaviorEnum
definition: Undergoes permanent deformation under stress

BRITTLE
type: Class
title: Brittle
subclass of: MechanicalBehaviorEnum
definition: Breaks without significant plastic deformation

HEXAGONAL
type: Class
title: Hexagonal
subclass of: CrystalSystemEnum
definition: Crystal system with one sixfold axis (a=b≠c, α=β=90°, γ=120°)

PROTOGYNOUS
type: Class
subclass of: PlantSexualSystem
definition: Starting as female and changing to male at a later stage

PROTANDROUS
type: Class
subclass of: PlantSexualSystem
definition: Starting as male and changing to female at a later stage

THERMOPLASTIC
type: Class
title: Thermoplastic
subclass of: PolymerTypeEnum
definition: Polymer that becomes moldable above specific temperature

AEROPONIC_GROWTH
type: Class
title: aeroponic plant growth media exposure
subclass of: PlantGrowthMediumExposureEnum
definition: Growing plants in air and/or mist environment without soil or aggregate medium

TEMPERATE_REGION
type: Class
title: temperate region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in regions with temperate climate, characterized by roughly equal winters and summers

RABI_SEASON
type: Class
title: rabi season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the rabi crop season (October-March) as practiced in South Asia

KHARIF_SEASON
type: Class
title: kharif season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the kharif crop season (May-October) as practiced in South Asia

WINTER_SEASON
type: Class
title: winter season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the winter season

SUMMER_SEASON
type: Class
title: summer season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the summer season

SPRING_SEASON
type: Class
title: spring season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the spring season

AUTUMN_SEASON
type: Class
title: autumn season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the autumn season

SOIL_ENVIRONMENT
type: Class
title: soil environment exposure
subclass of: PlantGrowthMediumExposureEnum
definition: Growing plants in soil growth media with varying contents

TROPICAL_REGION
type: Class
title: tropical region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in the geographical region between the Tropics of Cancer and Capricorn

HYDROPONIC_CULTURE
type: Class
title: hydroponic plant culture media exposure
subclass of: PlantGrowthMediumExposureEnum
definition: Growing plants in liquid growth media

ALTITUDE
type: Class
title: altitude exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth at a given elevation or height above sea level

ATMOSPHERIC_PRESSURE
type: Class
title: atmospheric pressure exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth at a given air pressure

GREENHOUSE_STUDY
type: Class
title: greenhouse study
subclass of: PlantStudyConditionEnum
definition: Plants were grown under greenhouse conditions

LABORATORY_STUDY
type: Class
title: laboratory study
subclass of: PlantStudyConditionEnum
definition: Plants were grown under in vitro growth conditions in a laboratory

FIELD_STUDY
type: Class
title: field study
subclass of: PlantStudyConditionEnum
definition: Plants were grown outdoors under field conditions

IN_VITRO_GROWTH_MEDIUM
type: Class
title: in vitro growth medium exposure
subclass of: PlantGrowthMediumExposureEnum
definition: In vitro culture using solid or liquid substrate with nutrients and amendments

GROWTH_CHAMBER_STUDY
type: Class
title: growth chamber study
subclass of: PlantStudyConditionEnum
definition: Plants were grown in growth chambers under controlled light and temperature conditions

RAINY_SEASON
type: Class
title: rainy season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the wet or rainy season

DRY_SEASON
type: Class
title: dry season exposure
subclass of: SeasonalEnvironmentExposureEnum
definition: Growth during the dry season

IRRIGATED_LAND_REGION
type: Class
title: irrigated land region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in leveled land with water control and shallow flooding

LOWLAND_REGION
type: Class
title: lowland region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in slightly steep regions with noncontinuous flooding and alternating aerobic/anaerobic soil

UPLAND_REGION
type: Class
title: upland region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in steep regions that are rarely flooded with aerobic soil

DESERT_LIKE_REGION
type: Class
title: desert-like region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in biome characterized by low moisture and infrequent precipitation

FLOOD_PRONE_REGION
type: Class
title: flood-prone region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in conditions susceptible to inundation by water

SUB_TROPICAL_REGION
type: Class
title: sub-tropical region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in regions adjacent to the tropics (roughly 25-40 degrees latitude)

SEMIARID_REGION
type: Class
title: semiarid region exposure
subclass of: EcologicalEnvironmentExposureEnum
definition: Growth in regions with 25-50cm (10-20 inches) annual rainfall

FRUIT_DEVELOPMENT_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stage of fruit formation through ripening

LEAF_DEVELOPMENT_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stages in leaf formation and expansion

MATURITY_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: mature plant embryo stage
definition: Stage when plant or plant embryo reaches full development

SEED_DEVELOPMENT_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stage from fertilization to mature seed

SENESCENCE_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: sporophyte senescent stage
definition: Stage of aging with loss of function and organ deterioration

SEED_GERMINATION_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stage beginning with seed imbibition and ending with radicle emergence

REPRODUCTIVE_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: sporophyte reproductive stage
definition: Stage from reproductive structure initiation to senescence onset

SEEDLING_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: seedling development stage
definition: Stage from germination until development of first adult vascular leaf

DORMANCY_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: sporophyte dormant stage
definition: Stage of suspended physiological activity and growth

VEGETATIVE_GROWTH_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: sporophyte vegetative stage
definition: Stage of growth before reproductive structure formation

ROOT_DEVELOPMENT_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stages in root growth and development

FLOWERING_STAGE
type: Class
subclass of: PlantDevelopmentalStage
definition: Stage when flowers open with pollen release and/or receptive stigma

EMBRYO_DEVELOPMENT_STAGE
type: Class
subclass of: PlantDevelopmentalStage
alternative label: plant embryo development stage
definition: Stage from zygote first division to seed germination initiation

PLANT_STRUCTURE
type: Class
subclass of: SESARMaterialType
definition: Plant structure or tissue

PARASITOID_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A parasite that kills or sterilizes its host

ADJACENT_TO
type: Class
title: Next to or adjoining
subclass of: SpatialRelationship
alternative label: adjacent to

SURROUNDS
type: Class
title: Encircles or encompasses
subclass of: SpatialRelationship
alternative label: surrounds

OBLIGATE_PARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relation of parasite-of in which the parasite that cannot complete its life cycle without a host.

FACULTATIVE_PARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relations of parasite-of in which the parasite that can complete its life cycle independent of a host.

STEM_PARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A parasite-of relationship in which the host is a plant and the parasite that attaches to the host stem.

ROOT_PARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A parasite-of relationship in which the host is a plant and the parasite that attaches to the host root.

HEMIPARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relation of parasite-of in which the parasite is a plant, and the parasite is parasitic under natural conditions and is also photosynthetic to some degree.

CAUSALLY_UPSTREAM_OF_POSITIVE_EFFECT
type: Class
title: causally upstream of, positive effect
subclass of: RO_0002411
subclass of: CausalPredicateEnum
direction: POSITIVE
symbol: +

CAUSALLY_UPSTREAM_OF_NEGATIVE_EFFECT
type: Class
title: causally upstream of, negative effect
subclass of: RO_0002411
subclass of: CausalPredicateEnum
direction: NEGATIVE
symbol: -

INDIRECTLY_POSITIVELY_REGULATES
type: Class
title: indirectly positively regulates
subclass of: RO_0002213
subclass of: CausalPredicateEnum
direction: POSITIVE
directness: INDIRECT

INDIRECTLY_NEGATIVELY_REGULATES
type: Class
title: indirectly negatively regulates
subclass of: RO_0002212
subclass of: CausalPredicateEnum
direction: NEGATIVE
directness: INDIRECT

PROVIDES_INPUT_FOR
type: Class
title: provides input for
subclass of: CausalPredicateEnum

PREYS_ON
type: Class
subclass of: RO_0002438
subclass of: BioticInteractionType
definition: An interaction relationship involving a predation process, where the subject kills the target in order to eat it or to feed to siblings, offspring or group members.

COMMENSUALLY_INTERACTS_WITH
type: Class
subclass of: RO_0002440
subclass of: BioticInteractionType
definition: An interaction relationship between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected.

MUTUALISTICALLY_INTERACTS_WITH
type: Class
subclass of: RO_0002440
subclass of: BioticInteractionType
definition: An interaction relationship between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other.

PARTICIPATES_IN_ABIOTIC_BIOTIC_INTERACTION_WITH
type: Class
title: participates in a abiotic-biotic interaction with
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: A biotic interaction relationship in which one partner is an organism and the other partner is inorganic. For example, the relationship between a sponge and the substrate to which is it anchored.

POLLINATES
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction where an organism transfers pollen to a plant

ACQUIRES_NUTRIENTS_FROM
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of provides nutrients for

PREYED_UPON_BY
type: Class
subclass of: RO_0002438
subclass of: BioticInteractionType
definition: Inverse of preys on

IS_VECTOR_FOR
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Organism acts as a vector for transmitting another organism

PROVIDES_NUTRIENTS_FOR
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: A biotic interaction where a material entity provides nutrition for an organism.

EATS
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: A biotic interaction where one organism consumes a material entity through a type of mouth or other oral opening.

IS_EATEN_BY
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of eats

HYPERPARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: x is a hyperparasite of y iff x is a parasite of a parasite of the target organism y

ALLELOPATH_OF
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: A relationship between organisms where one organism is influenced by the biochemicals produced by another. Allelopathy is a phenomenon in which one organism releases chemicals to positively or negatively influence the growth, survival or reproduction of other organisms in its vicinity.

PATHOGEN_OF
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of has pathogen

HAS_PATHOGEN
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: A host interaction where the smaller of the two members of a symbiosis causes a disease in the larger member.

VISITS_FLOWERS_OF
type: Class
subclass of: RO_0002618
subclass of: BioticInteractionType
definition: An interaction where an organism visits the flowers of a plant

HAS_FLOWERS_VISITED_BY
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of visits flowers of

LAYS_EGGS_IN
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction where an organism deposits eggs inside another organism

HAS_EGGS_LAID_IN_BY
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of lays eggs in

DIRECTLY_POSITIVELY_REGULATES
type: Class
title: directly positively regulates
subclass of: RO_0002213
subclass of: CausalPredicateEnum
direction: POSITIVE
directness: DIRECT

DIRECTLY_NEGATIVELY_REGULATES
type: Class
title: directly negatively regulates
subclass of: RO_0002212
subclass of: CausalPredicateEnum
direction: NEGATIVE
directness: DIRECT

ECTOPARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relation of parasite-of in which the parasite lives on or in the integumental system of the host.

MESOPARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relation of parasite-of in which the parasite is partially an endoparasite and partially an ectoparasite.

INTERCELLULAR_ENDOPARASITE_OF
type: Class
subclass of: RO_0002634
subclass of: BioticInteractionType
definition: A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.

INTRACELLULAR_ENDOPARASITE_OF
type: Class
subclass of: RO_0002634
subclass of: BioticInteractionType
definition: A sub-relation of endoparasite-of in which the parasite inhabits host cells.

RESERVOIR_HOST_OF
type: Class
subclass of: RO_0002453
subclass of: BioticInteractionType
definition: A relation between a host organism and a hosted organism in which the hosted organism naturally occurs in an indefinitely maintained reservoir provided by the host.

HAS_RESERVOIR_HOST
type: Class
subclass of: RO_0002454
subclass of: BioticInteractionType
definition: Inverse of reservoir host of

EPIPHYTE_OF
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction relationship wherein a plant or algae is living on the outside surface of another plant.

KLEPTOPARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A sub-relation of parasite of in which a parasite steals resources from another organism, usually food or nest material.

CREATES_HABITAT_FOR
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction relationship wherein one organism creates a structure or environment that is lived in by another organism.

ECOLOGICALLY_CO_OCCURS_WITH
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.

LAYS_EGGS_ON
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.

HAS_EGGS_LAID_ON_BY
type: Class
subclass of: RO_0002437
subclass of: BioticInteractionType
definition: Inverse of lays eggs on

SYMBIOTROPHICALLY_INTERACTS_WITH
type: Class
subclass of: RO_0002440
subclass of: BioticInteractionType
definition: A trophic interaction in which one organism acquires nutrients through a symbiotic relationship with another organism.

TROPHIC_PARASITE_OF
type: Class
subclass of: RO_0002444
subclass of: BioticInteractionType
definition: A symbiotrophic interaction in which one organism acquires nutrients through a parasitic relationship with another organism.

IS_SMALL_MOLECULE_ACTIVATOR_OF
type: Class
title: is small molecule activator of
subclass of: RO_0012004
subclass of: CausalPredicateEnum
direction: POSITIVE

IS_SMALL_MOLECULE_INHIBITOR_OF
type: Class
title: is small molecule inhibitor of
subclass of: RO_0012004
subclass of: CausalPredicateEnum
direction: NEGATIVE

CONSTITUTIVELY_UPSTREAM_OF
type: Class
title: constitutively upstream of
subclass of: CausalPredicateEnum

REMOVES_INPUT_FOR
type: Class
title: removes input for
subclass of: CausalPredicateEnum

DIELS_ALDER
type: Class
title: Diels-Alder reaction
subclass of: ReactionTypeEnum
definition: [4+2] cycloaddition reaction
components: diene + dienophile
type: pericyclic

MICHAEL_ADDITION
type: Class
title: Michael addition
subclass of: ReactionTypeEnum
definition: 1,4-addition to α,β-unsaturated carbonyl
type: conjugate addition

GRIGNARD
type: Class
title: Grignard reaction
subclass of: ReactionTypeEnum
definition: Organometallic addition reaction
reagent: RMgX

WITTIG
type: Class
title: Wittig reaction
subclass of: ReactionTypeEnum
definition: Alkene formation from phosphonium ylide
product: alkene

ALDOL
type: Class
title: aldol condensation
subclass of: ReactionTypeEnum
definition: Condensation forming β-hydroxy carbonyl
mechanism: enolate addition

FRIEDEL_CRAFTS
type: Class
title: Friedel-Crafts reaction
subclass of: ReactionTypeEnum
definition: Electrophilic aromatic substitution
subtypes: alkylation, acylation

PROCESSED_PSEUDOGENE
type: Class
subclass of: SO_0000336
subclass of: GenomeFeatureType
definition: A pseudogene arising from reverse transcription of mRNA

TRANSPOSABLE_ELEMENT
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A DNA segment that can change its position within the genome

RIBOSOME_ENTRY_SITE
type: Class
subclass of: SO_0000409
subclass of: GenomeFeatureType
definition: Region where ribosome assembles on mRNA

ATTENUATOR
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: A sequence that causes transcription termination

TERMINATOR
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: The sequence of DNA located either at the end of the transcript that causes RNA polymerase to terminate transcription

EXON
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing

CONTIG
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: A contiguous sequence derived from sequence assembly

CLONE
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: A piece of DNA that has been inserted into a vector

PLASMID
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: A self-replicating circular DNA molecule

DELETION
type: Class
subclass of: SO_0001059
subclass of: GenomeFeatureType
definition: The removal of a sequences of nucleotides from the genome

FIVE_PRIME_SPLICE_SITE
type: Class
title: five_prime_cis_splice_site
subclass of: SO_0000162
subclass of: GenomeFeatureType
definition: The 5' splice site (donor site)

THREE_PRIME_SPLICE_SITE
type: Class
title: three_prime_cis_splice_site
subclass of: SO_0000162
subclass of: GenomeFeatureType
definition: The 3' splice site (acceptor site)

ENHANCER
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: A cis-acting sequence that increases transcription

PROMOTER
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: A regulatory region initiating transcription

OPERON
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A group of contiguous genes transcribed as a single unit

PRIMARY_TRANSCRIPT
type: Class
subclass of: SO_0000673
subclass of: GenomeFeatureType
definition: A transcript that has not been processed

INTRON
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A region of a primary transcript that is transcribed, but removed from within the transcript by splicing

FIVE_PRIME_UTR
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: 5' untranslated region

THREE_PRIME_UTR
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: 3' untranslated region

MRNA
type: Class
subclass of: SO_0000673
subclass of: GenomeFeatureType
definition: Messenger RNA; includes 5'UTR, coding sequences and 3'UTR

TFBS
type: Class
title: TF_binding_site
subclass of: SO_0000409
subclass of: GenomeFeatureType
definition: Transcription factor binding site

RRNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: Ribosomal RNA

TRNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: Transfer RNA

SNRNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: Small nuclear RNA

SNORNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: Small nucleolar RNA

MIRNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: MicroRNA

INVERTED_REPEAT
type: Class
subclass of: SO_0000657
subclass of: GenomeFeatureType
definition: A repeat where the sequence is repeated in the opposite orientation

ORIGIN_OF_REPLICATION
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: The origin of replication; starting site for duplication of a nucleic acid molecule

D_LOOP
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: Displacement loop; a region where DNA is displaced by an invading strand

STEM_LOOP
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: A double-helical region formed by base-pairing between adjacent sequences

CDS
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: Coding sequence; sequence of nucleotides that corresponds with the sequence of amino acids in a protein

START_CODON
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: The first codon to be translated

STOP_CODON
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: The codon that terminates translation

CHROMOSOME
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: Structural unit composed of DNA and proteins

NUCLEOTIDE_MATCH
type: Class
subclass of: SO_0000343
subclass of: GenomeFeatureType
definition: A match to a nucleotide sequence

PROTEIN_MATCH
type: Class
subclass of: SO_0000343
subclass of: GenomeFeatureType
definition: A match to a protein sequence

RIBOZYME
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: An RNA with catalytic activity

SIGNAL_PEPTIDE
type: Class
subclass of: SO_0000104
subclass of: GenomeFeatureType
definition: A peptide region that targets a polypeptide to a specific location

MATURE_PROTEIN_REGION
type: Class
subclass of: SO_0000104
subclass of: GenomeFeatureType
definition: The polypeptide sequence that remains after post-translational processing

POLYA_SIGNAL_SEQUENCE
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: The recognition sequence for the cleavage and polyadenylation machinery

POLYA_SITE
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: Polyadenylation site

CENTROMERE
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A region where chromatids are held together

TELOMERE
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: The terminal region of a linear chromosome

SILENCER
type: Class
subclass of: SO_0005836
subclass of: GenomeFeatureType
definition: A regulatory region which upon binding of transcription factors, suppresses transcription

ANTISENSE_RNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: RNA that is complementary to other RNA

DISPERSED_REPEAT
type: Class
subclass of: SO_0000657
subclass of: GenomeFeatureType
definition: A repeat that is interspersed in the genome

INSERTION
type: Class
subclass of: SO_0001059
subclass of: GenomeFeatureType
definition: The sequence of one or more nucleotides added between two adjacent nucleotides

EST_MATCH
type: Class
subclass of: SO_0000343
subclass of: GenomeFeatureType
definition: A match to an EST sequence

CDNA_MATCH
type: Class
subclass of: SO_0000343
subclass of: GenomeFeatureType
definition: A match to a cDNA sequence

GENE
type: Class
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript

TANDEM_REPEAT
type: Class
subclass of: SO_0000657
subclass of: GenomeFeatureType
definition: A repeat where the same sequence is repeated in the same orientation

TRANSIT_PEPTIDE
type: Class
subclass of: SO_0000104
subclass of: GenomeFeatureType
definition: A peptide that directs the transport of a protein to an organelle

LINEAR
type: Class
subclass of: SequenceTopology
definition: Linear sequence molecule

CIRCULAR
type: Class
subclass of: SequenceTopology
definition: Circular sequence molecule

MOBILE_ELEMENT
type: Class
title: mobile_genetic_element
subclass of: SO_0001411
subclass of: GenomeFeatureType
definition: A nucleotide region with the ability to move from one place in the genome to another

PROPEPTIDE
type: Class
title: propeptide
subclass of: SO_0000104
subclass of: GenomeFeatureType
definition: A peptide region that is cleaved during maturation

LNCRNA
type: Class
subclass of: SO_0000655
subclass of: GenomeFeatureType
definition: Long non-coding RNA

SUBSTITUTION
type: Class
subclass of: SO_0001059
subclass of: GenomeFeatureType
definition: A sequence alteration where one nucleotide replaced by another

DUPLICATION
type: Class
subclass of: SO_0001059
subclass of: GenomeFeatureType
definition: One or more nucleotides are added between two adjacent nucleotides

INVERSION
type: Class
subclass of: SO_0001059
subclass of: GenomeFeatureType
definition: A continuous nucleotide sequence is inverted in the same position

ANOMALY
type: Class
title: Anomaly
subclass of: AnomalyDetectionEnum
alternative label: 1
alternative label: abnormal
alternative label: irregular
alternative label: outlier
definition: Abnormal, unexpected behavior or pattern

BLOCK_DESIGN
type: Class
title: Block design paradigm
subclass of: FMRIParadigmTypeEnum
definition: Alternating blocks of task and rest conditions
advantage: high statistical power
duration: typically 15-30 seconds per block
typical use: robust activation detection

FPKM
type: Class
subclass of: ExpressionUnitEnum
alternative label: Fragments per kilobase of transcript per million reads mapped
definition: Fragments per kilobase of transcript per million reads mapped
library type: paired-end
normalization: length and depth
use: within-sample comparisons

RPKM
type: Class
subclass of: ExpressionUnitEnum
alternative label: Reads per kilobase of transcript per million reads mapped
definition: Reads per kilobase of transcript per million reads mapped
library type: single-end
normalization: length and depth
use: within-sample comparisons

MONTE_CARLO
type: Class
subclass of: MaterialsSimulationType
definition: Stochastic simulation method using random sampling to explore configuration space

PHYLUM
type: Class
subclass of: TaxonomicRank
definition: Phylum (animals, plants, fungi) or Division (plants)

CLASS
type: Class
subclass of: TaxonomicRank
definition: Class

ORDER
type: Class
subclass of: TaxonomicRank
definition: Order

FAMILY
type: Class
subclass of: TaxonomicRank
definition: Family

GENUS
type: Class
subclass of: TaxonomicRank
definition: Genus

SPECIES
type: Class
subclass of: TaxonomicRank
definition: Species

VARIETY
type: Class
title: varietas
subclass of: TaxonomicRank
definition: Variety (mainly plants)

KINGDOM
type: Class
subclass of: TaxonomicRank
definition: Kingdom

SUBSPECIES
type: Class
subclass of: TaxonomicRank
definition: Subspecies

FORM
type: Class
title: forma
subclass of: TaxonomicRank
definition: Form (mainly plants)

CULTIVAR
type: Class
subclass of: TaxonomicRank
definition: Cultivar (cultivated variety)

DOMAIN
type: Class
subclass of: TaxonomicRank
definition: Domain (highest rank)

STRAIN
type: Class
subclass of: TaxonomicRank
definition: Strain (especially for microorganisms)

ENDOCRINE
type: Class
title: Hormone-producing glands
subclass of: AnatomicalSystemEnum
alternative label: endocrine system
components: pituitary, thyroid, adrenals, pancreas

REPRODUCTIVE
type: Class
title: Reproductive organs
subclass of: AnatomicalSystemEnum
alternative label: reproductive system
components: gonads, ducts, external genitalia

RESPIRATORY
type: Class
title: Lungs and airways
subclass of: AnatomicalSystemEnum
alternative label: respiratory system
components: lungs, trachea, bronchi, diaphragm

DIGESTIVE
type: Class
title: GI tract and accessory organs
subclass of: AnatomicalSystemEnum
alternative label: digestive system
components: mouth, esophagus, stomach, intestines, liver, pancreas

URINARY
type: Class
title: Kidneys and urinary tract
subclass of: AnatomicalSystemEnum
alternative label: renal system
components: kidneys, ureters, bladder, urethra

NERVOUS
type: Class
title: Brain, spinal cord, and nerves
subclass of: AnatomicalSystemEnum
alternative label: nervous system
components: brain, spinal cord, nerves

MUSCULOSKELETAL
type: Class
title: Bones, muscles, and connective tissue
subclass of: AnatomicalSystemEnum
alternative label: musculoskeletal system
components: bones, muscles, tendons, ligaments, cartilage

HEMATOLOGIC
type: Class
title: Blood and blood-forming organs
subclass of: AnatomicalSystemEnum
alternative label: hematopoietic system
components: blood, bone marrow, spleen

IMMUNE
type: Class
title: Immune and lymphatic system
subclass of: AnatomicalSystemEnum
alternative label: immune system
components: lymph nodes, spleen, thymus, bone marrow

INTEGUMENTARY
type: Class
title: Skin and related structures
subclass of: AnatomicalSystemEnum
alternative label: integumental system
components: skin, hair, nails, glands

CARDIOVASCULAR
type: Class
title: Heart and blood vessels
subclass of: AnatomicalSystemEnum
alternative label: cardiovascular system
components: heart, arteries, veins, capillaries

METER
type: Class
title: meter
subclass of: LengthUnitEnum
definition: Meter (SI base unit)
symbol: m
system: SI

KILOGRAM
type: Class
subclass of: MassUnitEnum
definition: Kilogram (SI base unit)
symbol: kg
system: SI

SECOND
type: Class
subclass of: TimeUnitEnum
definition: Second (SI base unit)
symbol: s
system: SI

KELVIN
type: Class
subclass of: TemperatureUnitEnum
definition: Kelvin (SI base unit)
absolute: true
symbol: K
system: SI

CENTIMETER
type: Class
subclass of: LengthUnitEnum
definition: Centimeter (0.01 meter)
conversion to meter: 0.01
symbol: cm

MILLIMETER
type: Class
subclass of: LengthUnitEnum
definition: Millimeter (0.001 meter)
conversion to meter: 0.001
symbol: mm

MICROMETER
type: Class
subclass of: LengthUnitEnum
definition: Micrometer/micron (10^-6 meter)
conversion to meter: 1e-6
symbol: μm

NANOMETER
type: Class
subclass of: LengthUnitEnum
definition: Nanometer (10^-9 meter)
conversion to meter: 1e-9
symbol: nm

ANGSTROM
type: Class
subclass of: LengthUnitEnum
definition: Angstrom (10^-10 meter)
conversion to meter: 1e-10
symbol: Å

GRAM
type: Class
subclass of: MassUnitEnum
definition: Gram (0.001 kilogram)
conversion to kg: 0.001
symbol: g

MILLIGRAM
type: Class
subclass of: MassUnitEnum
definition: Milligram (10^-6 kilogram)
conversion to kg: 1e-6
symbol: mg

MICROGRAM
type: Class
subclass of: MassUnitEnum
definition: Microgram (10^-9 kilogram)
conversion to kg: 1e-9
symbol: μg

NANOGRAM
type: Class
subclass of: MassUnitEnum
definition: Nanogram (10^-12 kilogram)
conversion to kg: 1e-12
symbol: ng

CELSIUS
type: Class
title: degree Celsius
subclass of: TemperatureUnitEnum
definition: Celsius/Centigrade
conversion: K - 273.15
symbol: °C

MILLISECOND
type: Class
subclass of: TimeUnitEnum
definition: Millisecond (0.001 second)
conversion to second: 0.001
symbol: ms

MICROSECOND
type: Class
subclass of: TimeUnitEnum
definition: Microsecond (10^-6 second)
conversion to second: 1e-6
symbol: μs

MINUTE
type: Class
subclass of: TimeUnitEnum
definition: Minute (60 seconds)
conversion to second: 60
symbol: min

HOUR
type: Class
subclass of: TimeUnitEnum
definition: Hour (3600 seconds)
conversion to second: 3600
symbol: h

DAY
type: Class
subclass of: TimeUnitEnum
definition: Day (86400 seconds)
conversion to second: 86400
symbol: d

WEEK
type: Class
subclass of: TimeUnitEnum
definition: Week (7 days)
conversion to second: 604800
symbol: wk

MONTH
type: Class
subclass of: TimeUnitEnum
definition: Month (approximately 30 days)
conversion to second: 2592000
note: approximate, varies by month
symbol: mo

YEAR
type: Class
subclass of: TimeUnitEnum
definition: Year (365.25 days)
conversion to second: 31557600
note: accounts for leap years
symbol: yr

MOLAR
type: Class
subclass of: ConcentrationUnitEnum
definition: Molar (moles per liter)
definition: mol/L
symbol: M

MILLIMOLAR
type: Class
subclass of: ConcentrationUnitEnum
definition: Millimolar (10^-3 molar)
conversion to molar: 0.001
symbol: mM

MICROMOLAR
type: Class
subclass of: ConcentrationUnitEnum
definition: Micromolar (10^-6 molar)
conversion to molar: 1e-6
symbol: μM

NANOMOLAR
type: Class
subclass of: ConcentrationUnitEnum
definition: Nanomolar (10^-9 molar)
conversion to molar: 1e-9
symbol: nM

PICOMOLAR
type: Class
subclass of: ConcentrationUnitEnum
definition: Picomolar (10^-12 molar)
conversion to molar: 1e-12
symbol: pM

CUBIC_METER
type: Class
subclass of: VolumeUnitEnum
definition: Cubic meter (SI derived)
symbol: m³
system: SI

CUBIC_CENTIMETER
type: Class
subclass of: VolumeUnitEnum
definition: Cubic centimeter
conversion to m3: 1e-6
symbol: cm³

MILLILITER
type: Class
subclass of: VolumeUnitEnum
definition: Milliliter (0.001 liter)
conversion to m3: 1e-6
symbol: mL

LITER
type: Class
subclass of: VolumeUnitEnum
definition: Liter (SI derived)
conversion to m3: 0.001
symbol: L

MICROLITER
type: Class
subclass of: VolumeUnitEnum
definition: Microliter (10^-6 liter)
conversion to m3: 1e-9
symbol: μL

HERTZ
type: Class
subclass of: FrequencyUnitEnum
definition: Hertz (cycles per second)
symbol: Hz
system: SI

PASCAL
type: Class
subclass of: PressureUnitEnum
definition: Pascal (SI derived unit)
definition: N/m²
symbol: Pa
system: SI

RADIAN
type: Class
subclass of: AngleUnitEnum
definition: Radian (SI derived unit)
symbol: rad
system: SI

NANOSECOND
type: Class
title: nanosecond
subclass of: TimeUnitEnum
definition: Nanosecond (10^-9 second)
conversion to second: 1e-9
symbol: ns

PPB
type: Class
title: parts per billion
subclass of: ConcentrationUnitEnum
definition: Parts per billion
conversion to fraction: 1e-9
symbol: ppb

MG_PER_ML
type: Class
title: milligram per milliliter
subclass of: ConcentrationUnitEnum
definition: Milligrams per milliliter
symbol: mg/mL

DEGREE
type: Class
subclass of: AngleUnitEnum
definition: Degree
conversion to radian: 0.0174533
symbol: °

PERCENT
type: Class
subclass of: ConcentrationUnitEnum
definition: Percent (parts per hundred)
conversion to fraction: 0.01
symbol: %

FAHRENHEIT
type: Class
title: degree Fahrenheit
subclass of: TemperatureUnitEnum
definition: Fahrenheit
conversion: (K - 273.15) * 9/5 + 32
symbol: °F
system: imperial

BYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Byte (8 bits)
conversion to bit: 8
symbol: B

KILOBYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Kilobyte (1000 bytes)
conversion to byte: 1000
standard: decimal
symbol: KB

MEGABYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Megabyte (10^6 bytes)
conversion to byte: 1e6
standard: decimal
symbol: MB

MM_HG
type: Class
title: millimetres of mercury
subclass of: PressureUnitEnum
definition: Millimeters of mercury
conversion to pascal: 133.322
symbol: mmHg
use: medical blood pressure

UG_PER_ML
type: Class
title: microgram per milliliter
subclass of: ConcentrationUnitEnum
definition: Micrograms per milliliter
symbol: μg/mL

NG_PER_ML
type: Class
title: nanogram per milliliter
subclass of: ConcentrationUnitEnum
definition: Nanograms per milliliter
symbol: ng/mL

MEGAHERTZ
type: Class
title: megaHertz
subclass of: FrequencyUnitEnum
definition: Megahertz (10^6 Hz)
conversion to hz: 1e6
symbol: MHz

INCH
type: Class
title: inch
subclass of: LengthUnitEnum
definition: Inch (imperial)
conversion to meter: 0.0254
symbol: in
system: imperial

FOOT
type: Class
title: foot
subclass of: LengthUnitEnum
definition: Foot (imperial)
conversion to meter: 0.3048
symbol: ft
system: imperial

YARD
type: Class
title: yard
subclass of: LengthUnitEnum
definition: Yard (imperial)
conversion to meter: 0.9144
symbol: yd
system: imperial

MILE
type: Class
title: mile
subclass of: LengthUnitEnum
definition: Mile (imperial)
conversion to meter: 1609.344
symbol: mi
system: imperial

NAUTICAL_MILE
type: Class
title: nautical mile
subclass of: LengthUnitEnum
definition: Nautical mile
conversion to meter: 1852
symbol: nmi

FLUID_OUNCE_US
type: Class
title: fluid ounce
subclass of: VolumeUnitEnum
alternative label: imperial fluid ounce
definition: US fluid ounce
conversion to m3: 2.95735e-5
symbol: fl oz
system: US

PINT_US
type: Class
title: pint
subclass of: VolumeUnitEnum
alternative label: imperial pint
definition: US pint
conversion to m3: 0.000473176
symbol: pt
system: US

QUART_US
type: Class
title: quart
subclass of: VolumeUnitEnum
alternative label: imperial quart
definition: US quart
conversion to m3: 0.000946353
symbol: qt
system: US

GALLON_UK
type: Class
title: gallon
subclass of: VolumeUnitEnum
alternative label: imperial gallon
definition: UK/Imperial gallon
conversion to m3: 0.00454609
symbol: gal
system: imperial

OUNCE
type: Class
title: ounce
subclass of: MassUnitEnum
definition: Ounce (imperial)
conversion to kg: 0.0283495
symbol: oz
system: imperial

POUND
type: Class
title: pound
subclass of: MassUnitEnum
definition: Pound (imperial)
conversion to kg: 0.453592
symbol: lb
system: imperial

STONE
type: Class
title: stone
subclass of: MassUnitEnum
definition: Stone (imperial)
conversion to kg: 6.35029
symbol: st
system: imperial

METRIC_TON
type: Class
subclass of: MassUnitEnum
alternative label: ton
definition: Metric ton/tonne (1000 kilograms)
conversion to kg: 1000
symbol: t

TEASPOON
type: Class
title: united states customary teaspoon
subclass of: VolumeUnitEnum
definition: Teaspoon
conversion to m3: 4.92892e-6
symbol: tsp

TABLESPOON
type: Class
title: united states customary tablespoon
subclass of: VolumeUnitEnum
definition: Tablespoon
conversion to m3: 1.47868e-5
symbol: tbsp

CUP_US
type: Class
title: united states customary cup
subclass of: VolumeUnitEnum
definition: US cup
conversion to m3: 0.000236588
symbol: cup
system: US

PSI
type: Class
title: pounds per square inch
subclass of: PressureUnitEnum
alternative label: pound-force per square inch
definition: Pounds per square inch
conversion to pascal: 6894.76
symbol: psi
system: imperial

KILOMETER
type: Class
title: kilometer
subclass of: LengthUnitEnum
definition: Kilometer (1000 meters)
conversion to meter: 1000
symbol: km

LIVE_ATTENUATED_VACCINE
type: Class
subclass of: VaccineCategoryEnum
definition: A vaccine made from microbes that have been weakened in the laboratory

UNVACCINATED
type: Class
subclass of: VaccinationStatusEnum
definition: An organismal quality that indicates an organism is unvaccinated with any vaccine

CONTINUOUS
type: Class
subclass of: UpdateFrequency
definition: Data is updated continuously or in real-time.
iso duration: PT0S

AROMATIC
type: Class
subclass of: BondTypeEnum
definition: Aromatic bond
bond order: 1.5
delocalized: true

DOUBLE
type: Class
subclass of: BondTypeEnum
definition: Double covalent bond
bond order: 2
electrons shared: 4

QUADRUPLE
type: Class
subclass of: BondTypeEnum
definition: Quadruple bond (rare, in transition metals)
bond order: 4
electrons shared: 8

SINGLE
type: Class
subclass of: BondTypeEnum
definition: Single covalent bond
bond order: 1
electrons shared: 2

TRIPLE
type: Class
subclass of: BondTypeEnum
definition: Triple covalent bond
bond order: 3
electrons shared: 6

ANNOTATION
type: Class
subclass of: PublicationType
definition: Annotation or scholarly note

BACHELORS_THESIS
type: Class
subclass of: PublicationType
definition: Bachelor's or undergraduate thesis

BLOG_POST
type: Class
subclass of: PublicationType
definition: Academic blog post

CASE_REPORT
type: Class
subclass of: PublicationType
definition: Clinical or scientific case report

CONFERENCE_ABSTRACT
type: Class
subclass of: PublicationType
definition: Conference abstract

CONFERENCE_POSTER
type: Class
subclass of: PublicationType
definition: Conference poster

EDITED_BOOK
type: Class
subclass of: PublicationType
definition: Edited collection or anthology

EDITORIAL
type: Class
subclass of: PublicationType
definition: Editorial or opinion piece

LETTER
type: Class
subclass of: PublicationType
definition: Letter to the editor

MASTERS_THESIS
type: Class
subclass of: PublicationType
definition: Master's thesis

PATENT
type: Class
subclass of: PublicationType
definition: Patent or patent application

POLICY_BRIEF
type: Class
subclass of: PublicationType
definition: Policy brief or recommendation

PROTOCOL
type: Class
subclass of: PublicationType
definition: Research protocol or methodology

REFERENCE_BOOK
type: Class
subclass of: PublicationType
definition: Reference work or encyclopedia

REVIEW_ARTICLE
type: Class
subclass of: PublicationType
definition: Review article synthesizing existing research

TEXTBOOK
type: Class
subclass of: PublicationType
definition: Educational textbook

WHITE_PAPER
type: Class
subclass of: PublicationType
definition: White paper or position paper

WORKING_PAPER
type: Class
subclass of: PublicationType
definition: Working paper or discussion paper

ABSORBED_DOSE
type: Class
title: absorbed dose
subclass of: QuantityKindEnum
definition: Energy deposited per unit mass by ionizing radiation
dimension: L²·T⁻²

ACCELERATION
type: Class
title: acceleration
subclass of: QuantityKindEnum
definition: Rate of change of velocity
dimension: L·T⁻²

ACTIVITY
type: Class
title: activity (radioactivity)
subclass of: QuantityKindEnum
definition: Number of nuclear disintegrations per unit time
dimension: T⁻¹

AMOUNT_CONCENTRATION
type: Class
title: amount concentration
subclass of: QuantityKindEnum
definition: Amount of substance per unit volume (molarity)
dimension: N·L⁻³

AMOUNT_OF_SUBSTANCE
type: Class
title: amount of substance
subclass of: QuantityKindEnum
definition: The number of elementary entities (atoms, molecules, etc.)
dimension: N
pato label: amount
si base: true

ANGLE
type: Class
title: plane angle
subclass of: QuantityKindEnum
definition: The figure formed by two rays sharing a common endpoint
dimension: dimensionless

ANGULAR_ACCELERATION
type: Class
title: angular acceleration
subclass of: QuantityKindEnum
definition: Rate of change of angular velocity
dimension: T⁻²

ANGULAR_VELOCITY
type: Class
title: angular velocity
subclass of: QuantityKindEnum
definition: Rate of change of angular position
dimension: T⁻¹

AREA
type: Class
title: area
subclass of: QuantityKindEnum
definition: A 2-D extent representing the size of a surface
dimension: L²

CAPACITANCE
type: Class
title: capacitance
subclass of: QuantityKindEnum
definition: Ability to store electric charge
dimension: I²·T⁴·M⁻¹·L⁻²

ELECTRICAL_CONDUCTIVITY
type: Class
title: electrical conductivity
subclass of: QuantityKindEnum
definition: Ability to conduct electric current
dimension: I²·T³·M⁻¹·L⁻³

DATA_RATE
type: Class
title: data rate
subclass of: QuantityKindEnum
definition: Amount of data transferred per unit time
dimension: T⁻¹

DENSITY
type: Class
title: density
subclass of: QuantityKindEnum
definition: Mass per unit volume
dimension: M·L⁻³
pato label: mass density

DOSE_EQUIVALENT
type: Class
title: dose equivalent
subclass of: QuantityKindEnum
definition: Absorbed dose weighted by radiation type
dimension: L²·T⁻²

VISCOSITY
type: Class
title: dynamic viscosity
subclass of: QuantityKindEnum
definition: Internal resistance to flow
dimension: M·L⁻¹·T⁻¹

ELECTRIC_CHARGE
type: Class
title: electric charge
subclass of: QuantityKindEnum
definition: Fundamental property of matter causing electromagnetic interaction
dimension: I·T

ELECTRIC_CURRENT
type: Class
title: electric current
subclass of: QuantityKindEnum
definition: Flow of electric charge per unit time
dimension: I
si base: true

ELECTRIC_POTENTIAL
type: Class
title: electric potential
subclass of: QuantityKindEnum
alternative label: voltage
definition: Potential energy per unit charge (voltage)
dimension: M·L²·T⁻³·I⁻¹

ENERGY
type: Class
title: energy
subclass of: QuantityKindEnum
definition: Capacity to do work
dimension: M·L²·T⁻²

FORCE
type: Class
title: force
subclass of: QuantityKindEnum
definition: Rate of change of momentum
dimension: M·L·T⁻²

FREQUENCY
type: Class
title: frequency
subclass of: QuantityKindEnum
definition: Number of repetitive events per unit time
dimension: T⁻¹

HEAT_CAPACITY
type: Class
title: heat capacity
subclass of: QuantityKindEnum
definition: Heat required to raise temperature by one unit
dimension: M·L²·T⁻²·Θ⁻¹

ILLUMINANCE
type: Class
title: illuminance
subclass of: QuantityKindEnum
definition: Luminous flux per unit area
dimension: J·L⁻²

INDUCTANCE
type: Class
title: inductance
subclass of: QuantityKindEnum
definition: Property relating magnetic flux to electric current
dimension: M·L²·T⁻²·I⁻²

INFORMATION_ENTROPY
type: Class
title: information entropy
subclass of: QuantityKindEnum
definition: Measure of information content or uncertainty
dimension: dimensionless

KINEMATIC_VISCOSITY
type: Class
title: kinematic viscosity
subclass of: QuantityKindEnum
definition: Dynamic viscosity divided by density
dimension: L²·T⁻¹

LENGTH
type: Class
title: length
subclass of: QuantityKindEnum
definition: A 1-D extent quality representing distance between two points
dimension: L
si base: true

LUMINOUS_FLUX
type: Class
title: luminous flux
subclass of: QuantityKindEnum
definition: Total perceived light power emitted
dimension: J

LUMINOUS_INTENSITY
type: Class
title: luminous intensity
subclass of: QuantityKindEnum
definition: Luminous power per unit solid angle emitted by a point light source
dimension: J
pato label: luminance
si base: true

MAGNETIC_FLUX
type: Class
title: magnetic flux
subclass of: QuantityKindEnum
definition: Measure of total magnetic field passing through a surface
dimension: M·L²·T⁻²·I⁻¹

MAGNETIC_FLUX_DENSITY
type: Class
title: magnetic flux density
subclass of: QuantityKindEnum
definition: Magnetic flux per unit area
dimension: M·T⁻²·I⁻¹

MASS
type: Class
title: mass
subclass of: QuantityKindEnum
definition: The amount of matter in an object
dimension: M
si base: true

MASS_CONCENTRATION
type: Class
title: mass concentration
subclass of: QuantityKindEnum
definition: Mass of a substance per unit volume
dimension: M·L⁻³
pato label: concentration of

MOMENTUM
type: Class
title: momentum
subclass of: QuantityKindEnum
definition: Product of mass and velocity
dimension: M·L·T⁻¹

POWER
type: Class
title: power
subclass of: QuantityKindEnum
definition: Rate of doing work or transferring energy
dimension: M·L²·T⁻³

PRESSURE
type: Class
title: pressure
subclass of: QuantityKindEnum
definition: Force per unit area
dimension: M·L⁻¹·T⁻²

RADIANT_INTENSITY
type: Class
title: radiant intensity
subclass of: QuantityKindEnum
definition: Radiant power per unit solid angle
dimension: M·L²·T⁻³

ELECTRIC_RESISTANCE
type: Class
title: electric resistance
subclass of: QuantityKindEnum
definition: Opposition to electric current flow
dimension: M·L²·T⁻³·I⁻²

SOLID_ANGLE
type: Class
title: solid angle
subclass of: QuantityKindEnum
definition: A 3-D angular measure
dimension: dimensionless

SPECIFIC_HEAT_CAPACITY
type: Class
title: specific heat capacity
subclass of: QuantityKindEnum
definition: Heat capacity per unit mass
dimension: L²·T⁻²·Θ⁻¹

SPEED
type: Class
title: speed
subclass of: QuantityKindEnum
definition: Scalar rate of change of position
dimension: L·T⁻¹

THERMAL_CONDUCTIVITY
type: Class
title: thermal conductivity
subclass of: QuantityKindEnum
definition: Ability to conduct heat
dimension: M·L·T⁻³·Θ⁻¹
pato label: heat conductivity

THERMODYNAMIC_TEMPERATURE
type: Class
title: thermodynamic temperature
subclass of: QuantityKindEnum
definition: The thermal energy of a system
dimension: Θ
pato label: temperature
si base: true

TIME
type: Class
title: time
subclass of: QuantityKindEnum
definition: Duration or temporal extent
dimension: T
pato label: duration
si base: true

TORQUE
type: Class
title: torque
subclass of: QuantityKindEnum
definition: Rotational force or moment of force
dimension: M·L²·T⁻²

VELOCITY
type: Class
title: velocity
subclass of: QuantityKindEnum
definition: Rate of change of position with direction
dimension: L·T⁻¹

VOLUME
type: Class
title: volume
subclass of: QuantityKindEnum
definition: A 3-D extent representing the amount of space occupied
dimension: L³

WORK
type: Class
title: work
subclass of: QuantityKindEnum
definition: Energy transferred by a force
dimension: M·L²·T⁻²

BTU
type: Class
subclass of: EnergyUnit
definition: British thermal unit
joules: 1.05506e+03
symbol: BTU
ucum: [Btu_IT]

CALORIE
type: Class
subclass of: EnergyUnit
definition: Calorie (cal)
joules: 4.184e+00
symbol: cal
ucum: cal

ELECTRON_VOLT
type: Class
subclass of: EnergyUnit
definition: Electron volt (eV)
joules: 1.602e-19
symbol: eV
ucum: eV

GIGAJOULE
type: Class
subclass of: EnergyUnit
definition: Gigajoule (GJ)
joules: 1e9
symbol: GJ
ucum: GJ

GIGAWATT
type: Class
subclass of: PowerUnit
definition: Gigawatt (GW)
symbol: GW
ucum: GW
watts: 1e9

GIGAWATT_HOUR
type: Class
subclass of: EnergyUnit
definition: Gigawatt-hour (GWh)
joules: 3.6e12
symbol: GWh
ucum: GW.h

HORSEPOWER
type: Class
subclass of: PowerUnit
definition: Horsepower
symbol: hp
ucum: [HP]
watts: 7.457e+02

JOULE
type: Class
subclass of: EnergyUnit
definition: Joule (J)
si base: true
symbol: J
ucum: J

KILOCALORIE
type: Class
subclass of: EnergyUnit
definition: Kilocalorie (kcal)
joules: 4184
symbol: kcal
ucum: kcal

KILOJOULE
type: Class
subclass of: EnergyUnit
definition: Kilojoule (kJ)
joules: 1000
symbol: kJ
ucum: kJ

KILOWATT
type: Class
subclass of: PowerUnit
definition: Kilowatt (kW)
symbol: kW
ucum: kW
watts: 1000

KILOWATT_HOUR
type: Class
subclass of: EnergyUnit
definition: Kilowatt-hour (kWh)
joules: 3.6e6
symbol: kWh
ucum: kW.h

MEGAJOULE
type: Class
subclass of: EnergyUnit
definition: Megajoule (MJ)
joules: 1e6
symbol: MJ
ucum: MJ

MEGAWATT
type: Class
subclass of: PowerUnit
definition: Megawatt (MW)
symbol: MW
ucum: MW
watts: 1e6

MEGAWATT_HOUR
type: Class
subclass of: EnergyUnit
definition: Megawatt-hour (MWh)
joules: 3.6e9
symbol: MWh
ucum: MW.h

THERM
type: Class
subclass of: EnergyUnit
definition: Therm
joules: 1.055e8
symbol: thm
ucum: [thm_us]

TOE
type: Class
subclass of: EnergyUnit
definition: Tonne of oil equivalent
joules: 4.187e10
symbol: toe
ucum: toe

TERAWATT
type: Class
subclass of: PowerUnit
definition: Terawatt (TW)
symbol: TW
ucum: TW
watts: 1e12

TERAWATT_HOUR
type: Class
subclass of: EnergyUnit
definition: Terawatt-hour (TWh)
joules: 3.6e15
symbol: TWh
ucum: TW.h

WATT
type: Class
subclass of: PowerUnit
definition: Watt (W)
si base: true
symbol: W
ucum: W

WATT_HOUR
type: Class
subclass of: EnergyUnit
definition: Watt-hour (Wh)
joules: 3600
symbol: Wh
ucum: W.h

REVIEW_COMPLETE
type: Class
title: completed
subclass of: PeerReviewStatus
definition: Peer review complete

UNDER_REVIEW
type: Class
title: ongoing
subclass of: PeerReviewStatus
definition: Currently under peer review

NON_TOXIC
type: Class
title: Non-Toxic
subclass of: ToxicityClassificationEnum
alternative label: 0
alternative label: clean
alternative label: safe
definition: Text is appropriate and non-harmful

INADEQUATE_HOUSING
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Unsatisfactory housing conditions
definition: Housing that does not meet basic standards for safety and habitability

HOUSING_INSTABILITY
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Housing instability
definition: Challenges with housing including trouble paying rent or frequent moves

ADOPTIVE
type: Class
subclass of: GeneticRelationship
definition: Relationship established through adoption

UNKNOWN_GENETIC_RELATIONSHIP
type: Class
subclass of: GeneticRelationship
definition: Genetic relationship status is unknown

ELASTOMER
type: Class
title: Elastomer
subclass of: PolymerTypeEnum
alternative label: rubber
definition: Polymer with elastic properties

FERROUS
type: Class
title: Ferrous Metal
subclass of: MetalTypeEnum
alternative label: iron-based
definition: Iron-based metals and alloys

NON_FERROUS
type: Class
title: Non-Ferrous Metal
subclass of: MetalTypeEnum
definition: Metals and alloys not containing iron

O_POSITIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type O, Rh positive
abo: O
can donate: A+, B+, AB+, O+
can receive: O+, O-
rh: positive

O_NEGATIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type O, Rh negative (universal donor)
abo: O
can donate: all types
can receive: O-
rh: negative
special: universal donor

A_POSITIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type A, Rh positive
abo: A
can donate: A+, AB+
can receive: A+, A-, O+, O-
rh: positive

B_POSITIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type B, Rh positive
abo: B
can donate: B+, AB+
can receive: B+, B-, O+, O-
rh: positive

AB_POSITIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type AB, Rh positive (universal recipient)
abo: AB
can donate: AB+
can receive: all types
rh: positive
special: universal recipient

A_NEGATIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type A, Rh negative
abo: A
can donate: A+, A-, AB+, AB-
can receive: A-, O-
rh: negative

B_NEGATIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type B, Rh negative
abo: B
can donate: B+, B-, AB+, AB-
can receive: B-, O-
rh: negative

AB_NEGATIVE
type: Class
subclass of: BloodTypeEnum
definition: Blood type AB, Rh negative
abo: AB
can donate: AB+, AB-
can receive: A-, B-, AB-, O-
rh: negative

HOMELESSNESS
type: Class
subclass of: GravitySdohDomainEnum
alternative label: Homeless
definition: The condition of lacking stable, safe, and adequate housing

NON_BINARY
type: Class
subclass of: GenderIdentity
definition: Identifies as gender nonbinary

NO_GENETIC_RELATIONSHIP
type: Class
subclass of: GeneticRelationship
definition: No genetic relationship exists

BSL1
type: Class
title: biosafety level 1
subclass of: BiosafetyLevelEnum
definition: Suitable for well-characterized agents not known to consistently cause disease in healthy adults

BSL2
type: Class
title: biosafety level 2
subclass of: BiosafetyLevelEnum
definition: Suitable for agents that pose moderate hazards to personnel and the environment

BSL3
type: Class
title: biosafety level 3
subclass of: BiosafetyLevelEnum
definition: Suitable for indigenous or exotic agents that may cause serious or potentially lethal disease through inhalation

BSL4
type: Class
title: biosafety level 4
subclass of: BiosafetyLevelEnum
definition: Suitable for dangerous and exotic agents that pose high risk of life-threatening disease

BIOLOGICAL
type: Class
subclass of: GeneticRelationship
definition: Genetic relationship through biological inheritance

FULL_SIBLING
type: Class
subclass of: GeneticRelationship
definition: Siblings sharing both biological parents

HALF_SIBLING
type: Class
subclass of: GeneticRelationship
definition: Siblings sharing one biological parent

FEMALE
type: Class
subclass of: GenderIdentity
definition: Identifies as female gender (finding)

MALE
type: Class
subclass of: GenderIdentity
definition: Identifies as male gender (finding)

LIGHT_METAL
type: Class
title: Light Metal
subclass of: MetalTypeEnum
definition: Low density metals (density < 5 g/cm³)

ALLOGRAFT
type: Class
subclass of: TransplantationTypeEnum
alternative label: allogeneic transplant
alternative label: homograft
definition: Transplantation of cells, tissues, or organs between genetically different individuals of the same species
donor recipient: same species, different individual
example: bone marrow transplant

ROBOTIC_ARM
type: Class
title: robotic arm
subclass of: LaboratoryDeviceTypeEnum
definition: A programmable mechanical arm used in laboratory automation

INDIAN_OCEAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Indian Ocean

BORNEO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Borneo
note: Island shared by Brunei, Indonesia, and Malaysia

TASMAN_SEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tasman Sea

PACIFIC_OCEAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Pacific Ocean

MEDITERRANEAN_SEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Mediterranean Sea

BALTIC_SEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Baltic Sea

NORTH_SEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: North Sea

ARCTIC_OCEAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Arctic Ocean

ATLANTIC_OCEAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Atlantic Ocean

ROSS_SEA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Ross Sea

SOUTHERN_OCEAN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Southern Ocean

AMERICAN_INDIAN_OR_ALASKA_NATIVE
type: Class
subclass of: OmbRaceCategory
definition: American Indian or Alaska Native

ASIAN
type: Class
subclass of: OmbRaceCategory
definition: Asian

BLACK_OR_AFRICAN_AMERICAN
type: Class
subclass of: OmbRaceCategory
definition: Black or African American

NATIVE_HAWAIIAN_OR_OTHER_PACIFIC_ISLANDER
type: Class
subclass of: OmbRaceCategory
definition: Native Hawaiian or Other Pacific Islander

WHITE
type: Class
subclass of: OmbRaceCategory
definition: White

OTHER_RACE
type: Class
subclass of: OmbRaceCategory
definition: Other Race (discouraged for statistical analysis)

HISPANIC_OR_LATINO
type: Class
subclass of: OmbEthnicityCategory
definition: Hispanic or Latino

NOT_HISPANIC_OR_LATINO
type: Class
subclass of: OmbEthnicityCategory
definition: Not Hispanic or Latino

ASKED_DECLINED
type: Class
subclass of: GenderIdentity
definition: Asked But Declined

NOT_ASKED
type: Class
subclass of: FamilyHistoryStatus
definition: Family history information was not requested

UNABLE_TO_OBTAIN
type: Class
subclass of: FamilyHistoryStatus
definition: Information could not be obtained due to patient/family constraints

UNKNOWN
type: Class
subclass of: FamilyHistoryStatus
definition: Family history status is unknown

as-text
type: Class
title: As Text
subclass of: DataAbsentEnum
definition: The content of the data is represented in the resource narrative.

asked-declined
type: Class
title: Asked But Declined
subclass of: data-absent-reasonunknown
subclass of: DataAbsentEnum
definition: The source was asked but declined to answer.

asked-unknown
type: Class
title: Asked But Unknown
subclass of: data-absent-reasonunknown
subclass of: DataAbsentEnum
definition: The source was asked but does not know the value.

masked
type: Class
title: Masked
subclass of: DataAbsentEnum
definition: The information is not available due to security, privacy or related reasons.

negative-infinity
type: Class
title: Negative Infinity (NINF)
subclass of: data-absent-reasonerror
subclass of: DataAbsentEnum
definition: The numeric value is excessively low and unrepresentable due to a floating point processing error.

not-a-number
type: Class
title: Not a Number (NaN)
subclass of: data-absent-reasonerror
subclass of: DataAbsentEnum
definition: The numeric value is undefined or unrepresentable due to a floating point processing error.

not-applicable
type: Class
title: Not Applicable
subclass of: DataAbsentEnum
definition: There is no proper value for this element (e.g. last menstrual period for a male).

not-asked
type: Class
title: Not Asked
subclass of: data-absent-reasonunknown
subclass of: DataAbsentEnum
definition: The workflow didn't lead to this value being known.

not-performed
type: Class
title: Not Performed
subclass of: DataAbsentEnum
definition: The value is not available because the observation procedure (test, etc.) was not performed.

not-permitted
type: Class
title: Not Permitted
subclass of: DataAbsentEnum
definition: The value is not permitted in this context (e.g. due to profiles, or the base data types).

positive-infinity
type: Class
title: Positive Infinity (PINF)
subclass of: data-absent-reasonerror
subclass of: DataAbsentEnum
definition: The numeric value is excessively high and unrepresentable due to a floating point processing error.

temp-unknown
type: Class
title: Temporarily Unknown
subclass of: data-absent-reasonunknown
subclass of: DataAbsentEnum
definition: There is reason to expect (from the workflow) that the value may become known.

unsupported
type: Class
title: Unsupported
subclass of: DataAbsentEnum
definition: The source system wasn't capable of supporting this element.

ANNULLED
type: Class
subclass of: MaritalStatus
definition: Marriage contract has been declared null and to not have existed

COMMON_LAW
type: Class
subclass of: MaritalStatus
definition: Marriage recognized in some jurisdictions based on parties' agreement

DIVORCED
type: Class
subclass of: MaritalStatus
definition: Marriage contract has been declared dissolved and inactive

INTERLOCUTORY
type: Class
subclass of: MaritalStatus
definition: Subject to an Interlocutory Decree

LEGALLY_SEPARATED
type: Class
subclass of: MaritalStatus
definition: Legally Separated

MARRIED
type: Class
subclass of: MaritalStatus
definition: A current marriage contract is active

POLYGAMOUS
type: Class
subclass of: MaritalStatus
definition: More than 1 current spouse

NEVER_MARRIED
type: Class
subclass of: MaritalStatus
definition: No marriage contract has ever been entered

DOMESTIC_PARTNER
type: Class
subclass of: MaritalStatus
definition: Person declares that a domestic partner relationship exists

UNMARRIED
type: Class
subclass of: MaritalStatus
definition: Currently not in a marriage contract

UNKNOWN
type: Class
subclass of: MaritalStatus
definition: A proper value is applicable, but not known

WIDOWED
type: Class
subclass of: MaritalStatus
definition: The spouse has died

COMPLETED
type: Class
subclass of: FamilyHistoryStatus
definition: All relevant family history information has been obtained

PARTIAL
type: Class
subclass of: FamilyHistoryStatus
definition: Some family history information is available but not complete

DOUBLING_UP
type: Class
subclass of: HousingStatus
definition: Patients who are doubling up with others

HOMELESS_SHELTER
type: Class
subclass of: HousingStatus
definition: Patients who are living in a homeless shelter

OTHER
type: Class
subclass of: HousingStatus
definition: Patients who have other kinds of accommodation

PERMANENT_SUPPORTIVE_HOUSING
type: Class
subclass of: HousingStatus
definition: Patients who are living in a permanent supportive housing

STREET
type: Class
subclass of: HousingStatus
definition: Patients who do not have a house and are living on the streets

TRANSITIONAL
type: Class
subclass of: HousingStatus
definition: Patients who do not have a house and are in a transitional state

UNKNOWN
type: Class
subclass of: HousingStatus
definition: Patients with Unknown accommodation

FULL_TIME_EMPLOYED
type: Class
subclass of: EmploymentStatus
definition: Full time employed

PART_TIME_EMPLOYED
type: Class
subclass of: EmploymentStatus
definition: Part time employed

UNEMPLOYED
type: Class
subclass of: EmploymentStatus
definition: Unemployed

SELF_EMPLOYED
type: Class
subclass of: EmploymentStatus
definition: Self-employed

RETIRED
type: Class
subclass of: EmploymentStatus
definition: Retired

ACTIVE_MILITARY
type: Class
subclass of: EmploymentStatus
definition: On active military duty

UNKNOWN
type: Class
subclass of: EmploymentStatus
definition: Unknown

CONTRACT
type: Class
subclass of: EmploymentStatus
definition: Contract, per diem

PER_DIEM
type: Class
subclass of: EmploymentStatus
definition: Per Diem

LEAVE_OF_ABSENCE
type: Class
subclass of: EmploymentStatus
definition: Leave of absence

OTHER
type: Class
subclass of: EmploymentStatus
definition: Other

TEMPORARILY_UNEMPLOYED
type: Class
subclass of: EmploymentStatus
definition: Temporarily unemployed

ASSOC
type: Class
subclass of: EducationLevel
definition: Associate's or technical degree complete

BD
type: Class
subclass of: EducationLevel
definition: College or baccalaureate degree complete

ELEM
type: Class
subclass of: EducationLevel
definition: Elementary School

GD
type: Class
subclass of: EducationLevel
definition: Graduate or professional Degree complete

HS
type: Class
subclass of: EducationLevel
definition: High School or secondary school degree complete

PB
type: Class
subclass of: EducationLevel
definition: Some post-baccalaureate education

POSTG
type: Class
subclass of: EducationLevel
definition: Doctoral or post graduate education

SCOL
type: Class
subclass of: EducationLevel
definition: Some College education

SEC
type: Class
subclass of: EducationLevel
definition: Some secondary or high school education

ADOPTIVE_FATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role (father) is a male who has taken the scoper (child) into their family through legal means and raises them as his own child

ADOPTIVE_MOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role (mother) is a female who has taken the scoper (child) into their family through legal means and raises them as her own child

ADOPTIVE_PARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role (parent) has taken the scoper (child) into their family through legal means and raises them as his or her own child

AUNT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a sister of the scoping person's mother or father

BROTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male sharing one or both parents with the scoping entity

BROTHER_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a brother of the scoping person's spouse, or the husband of the scoping person's sister, or the husband of a sister of the scoping person's spouse

CHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child of the scoping entity

ADOPTIVE_CHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child taken into a family through legal means and raised by the scoping person (parent) as his or her own child

FOSTER_CHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child receiving parental care and nurture from the scoping person (parent) but not related to him or her through legal or blood relationship

COUSIN
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a relative descended from a common ancestor, such as a grandparent, by two or more steps in a diverging line

DAUGHTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female offspring of the scoping entity (parent)

DAUGHTER_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the wife of scoping person's son

DOMESTIC_PARTNER
type: Class
subclass of: FamilyRelationship
definition: The player of the role cohabits with the scoping person but is not the scoping person's spouse

EXTENDED_FAMILY_MEMBER
type: Class
subclass of: FamilyRelationship
definition: Description of an extended family member

FAMILY_MEMBER
type: Class
subclass of: FamilyRelationship
definition: A relationship between two people characterizing their "familial" relationship

FATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male who begets or raises or nurtures the scoping entity (child)

FATHER_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the father of the scoping person's spouse

FRATERNAL_TWIN
type: Class
subclass of: FamilyRelationship
definition: The player of the role is born from the same pregnancy as the scoping entity but does not share the same genotype

GESTATIONAL_MOTHER
type: Class
subclass of: FamilyRelationship
definition: The player is a female whose womb carries the fetus of the scoper

GREAT_GRANDFATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a grandfather of the scoping person's mother or father

GREAT_GRANDMOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a grandmother of the scoping person's mother or father

GREAT_GRANDPARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a grandparent of the scoping person's mother or father

GRANDFATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the father of the scoping person's mother or father

GRANDMOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the mother of the scoping person's mother or father

GRANDCHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child of the scoping person's son or daughter

GRANDDAUGHTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a daughter of the scoping person's son or daughter

GRANDSON
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a son of the scoping person's son or daughter

GRANDPARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a parent of the scoping person's mother or father

HALF_BROTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male related to the scoping entity by sharing only one biological parent

HALF_SISTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female related to the scoping entity by sharing only one biological parent

HUSBAND
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a man joined to a woman (scoping person) in marriage

IDENTICAL_TWIN
type: Class
subclass of: FamilyRelationship
definition: The player of the role is born from the same pregnancy as the scoping entity and shares the same genotype

MATERNAL_AUNT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a sister of the scoping person's mother

MATERNAL_COUSIN
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child of a maternal aunt or uncle of the scoping person

MATERNAL_GRANDFATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the father of the scoping person's mother

MATERNAL_GRANDMOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the mother of the scoping person's mother

MOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female who conceives, gives birth to, or raises and nurtures the scoping entity (child)

MOTHER_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the mother of the scoping person's spouse

MATERNAL_UNCLE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a brother of the scoping person's mother

NATURAL_BROTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male related to the scoping entity by sharing only the same natural parents

NATURAL_CHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is an offspring of the scoping entity as determined by birth

NEPHEW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a son of the scoping person's brother or sister or of the brother or sister of the scoping person's spouse

NATURAL_FATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male who begets the scoping entity (child)

NIECE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a daughter of the scoping person's brother or sister or of the brother or sister of the scoping person's spouse

NATURAL_MOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female who conceives or gives birth to the scoping entity (child)

NATURAL_SISTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female related to the scoping entity by sharing only the same natural parents

PATERNAL_AUNT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a sister of the scoping person's father

PATERNAL_COUSIN
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child of a paternal aunt or uncle of the scoping person

PATERNAL_GRANDFATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the father of the scoping person's father

PATERNAL_GRANDMOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the mother of the scoping person's father

PARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is one who begets, gives birth to, or nurtures and raises the scoping entity (child)

FOSTER_PARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role (parent) who is a state-certified caregiver responsible for the scoper (child)

PATERNAL_UNCLE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a brother of the scoping person's father

SIBLING
type: Class
subclass of: FamilyRelationship
definition: The player of the role shares one or both parents in common with the scoping entity

SIGNIFICANT_OTHER
type: Class
subclass of: FamilyRelationship
definition: A person who is important to one's well being; especially a spouse or one in a similar relationship

SISTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female sharing one or both parents with the scoping entity

SISTER_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a sister of the scoping person's spouse, or the wife of the scoping person's brother, or the wife of a brother of the scoping person's spouse

SON
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male offspring of the scoping entity (parent)

SON_IN_LAW
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the husband of scoping person's daughter

SPOUSE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a marriage partner of the scoping person

STEP_BROTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male child of the scoping person's stepparent

STEP_CHILD
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a child of the scoping person's spouse by a previous union

STEP_FATHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the male spouse of the scoping person's parent and not the scoping person's natural father

STEP_MOTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the female spouse of the scoping person's parent and not the scoping person's natural mother

STEP_PARENT
type: Class
subclass of: FamilyRelationship
definition: The player of the role is the spouse of the scoping person's parent and not the scoping person's natural parent

STEP_SISTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female child of the scoping person's stepparent

TWIN
type: Class
subclass of: FamilyRelationship
definition: The scoper and player were carried in the same womb and delivered in the same birth

TWIN_BROTHER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a male born from the same pregnancy as the scoping entity

TWIN_SISTER
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a female born from the same pregnancy as the scoping entity

UNCLE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a brother of the scoping person's mother or father

WIFE
type: Class
subclass of: FamilyRelationship
definition: The player of the role is a woman joined to a man (scoping person) in marriage

REPORTER_GENE_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Reporter gene assay

HIGH_CONTENT_SCREEN
type: Class
subclass of: CellBasedAssayEnum
definition: High content screening assay

CELL_COUNT
type: Class
subclass of: CellBasedAssayEnum
definition: Cell counting assay

CELL_PROLIFERATION_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Cell proliferation measurement

MIGRATION_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Cell migration assay

CELL_VIABILITY_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Cell viability measurement assay

OXYGEN_CONSUMPTION_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Oxygen consumption rate measurement

CRISPR
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: CRISPR-Cas9
alternative label: CRISPR/Cas9
definition: CRISPR/Cas9 gene editing technology
mechanism: DNA cleavage and repair

CELL_PAINTING
type: Class
subclass of: CellBasedAssayEnum
definition: Cell painting morphological profiling

METALLIC
type: Class
subclass of: ElementMetallicClassificationEnum
definition: Metallic elements
properties: conductive, malleable, ductile

NON_METALLIC
type: Class
subclass of: ElementMetallicClassificationEnum
definition: Non-metallic elements
properties: poor conductors, brittle

SEMI_METALLIC
type: Class
subclass of: ElementMetallicClassificationEnum
definition: Semi-metallic/metalloid elements
properties: intermediate properties

IPSC_DERIVED
type: Class
subclass of: ModelSystemTypeEnum
alternative label: iPSC-derived
definition: Induced pluripotent stem cell-derived model

SPATIAL_TRANSCRIPTOMICS
type: Class
subclass of: SequencingAssayEnum
definition: Spatially resolved transcriptomics

MOUTH_PIPETTING
type: Class
title: mouth pipetting
subclass of: LiquidHandlingOperationEnum
definition: A method of using the researcher's mouth to apply small negative pressure to aspirate a volume into a pipette

EDUCATIONAL_ATTAINMENT
type: Class
subclass of: GravitySdohDomainEnum
alternative label: educational attainment
definition: Highest level of education completed

URL
type: Class
subclass of: MLDataType
definition: Uniform Resource Locators
mapping relation: URL

BOOLEAN
type: Class
subclass of: MLDataType
definition: Boolean values (true/false)
mapping relation: Boolean

DATE
type: Class
subclass of: MLDataType
definition: Date values
mapping relation: Date

DATETIME
type: Class
subclass of: MLDataType
definition: Combined date and time values
mapping relation: DateTime

FLOAT
type: Class
subclass of: MLDataType
definition: Floating point numbers
mapping relation: Float

INTEGER
type: Class
subclass of: MLDataType
definition: Integer numbers
mapping relation: IAO_0000031
mapping relation: Integer

TEXT
type: Class
subclass of: MLDataType
definition: Text or string data
mapping relation: http://edamontology.org/3671
mapping relation: Text

TIME
type: Class
subclass of: MLDataType
definition: Time values
mapping relation: Time

FRIDAY
type: Class
subclass of: DayOfWeek
definition: Friday
abbreviation: Fri
iso number: 5

MONDAY
type: Class
subclass of: DayOfWeek
definition: Monday (first day of week in ISO 8601)
abbreviation: Mon
iso number: 1

SATURDAY
type: Class
subclass of: DayOfWeek
definition: Saturday
abbreviation: Sat
iso number: 6

SUNDAY
type: Class
subclass of: DayOfWeek
definition: Sunday (last day of week in ISO 8601)
abbreviation: Sun
iso number: 7

THURSDAY
type: Class
subclass of: DayOfWeek
definition: Thursday
abbreviation: Thu
iso number: 4

TUESDAY
type: Class
subclass of: DayOfWeek
definition: Tuesday
abbreviation: Tue
iso number: 2

WEDNESDAY
type: Class
subclass of: DayOfWeek
definition: Wednesday
abbreviation: Wed
iso number: 3

COMPLETED
type: Class
subclass of: DatasetStatus
alternative label: Final
alternative label: Finished
definition: The dataset is complete and no further updates are planned. The data is in its final form.

DEPRECATED
type: Class
subclass of: DatasetStatus
alternative label: Legacy
alternative label: Superseded
definition: The dataset has been superseded by a newer version or is no longer recommended for use.

UNDER_DEVELOPMENT
type: Class
title: Under Development
subclass of: DatasetStatus
alternative label: Draft
alternative label: In Progress
alternative label: Work in Progress
definition: The dataset is still being created, collected, or processed. Not yet ready for production use.

WITHDRAWN
type: Class
subclass of: DatasetStatus
alternative label: Removed
alternative label: Retracted
definition: The dataset has been removed from availability, either temporarily or permanently.

APRIL
type: Class
subclass of: Month
definition: April
order: 4
abbreviation: Apr
days: 30

AUGUST
type: Class
subclass of: Month
definition: August
order: 8
abbreviation: Aug
days: 31

DECEMBER
type: Class
subclass of: Month
definition: December
order: 12
abbreviation: Dec
days: 31

FEBRUARY
type: Class
subclass of: Month
definition: February
order: 2
abbreviation: Feb
days: 28/29

JANUARY
type: Class
subclass of: Month
definition: January
order: 1
abbreviation: Jan
days: 31

JULY
type: Class
subclass of: Month
definition: July
order: 7
abbreviation: Jul
days: 31

JUNE
type: Class
subclass of: Month
definition: June
order: 6
abbreviation: Jun
days: 30

MARCH
type: Class
subclass of: Month
definition: March
order: 3
abbreviation: Mar
days: 31

MAY
type: Class
subclass of: Month
definition: May
order: 5
abbreviation: May
days: 31

NOVEMBER
type: Class
subclass of: Month
definition: November
order: 11
abbreviation: Nov
days: 30

OCTOBER
type: Class
subclass of: Month
definition: October
order: 10
abbreviation: Oct
days: 31

SEPTEMBER
type: Class
subclass of: Month
definition: September
order: 9
abbreviation: Sep
days: 30

CDISC
type: Class
subclass of: ValueSetStewardEnum
alternative label: Clinical Data Interchange Standards Consortium
definition: Clinical Data Interchange Standards Consortium. Develops global data standards for clinical research including CDASH, SDTM, and ADaM.
established: 1997

CONCEPTUALIZATION
type: Class
subclass of: ResearchRole
definition: Ideas; formulation of research goals

METHODOLOGY
type: Class
subclass of: ResearchRole
definition: Development of methodology

RESOURCES
type: Class
subclass of: ResearchRole
definition: Provision of materials and tools

SOFTWARE
type: Class
subclass of: ResearchRole
definition: Programming and software development

VALIDATION
type: Class
subclass of: ResearchRole
definition: Verification of results

VISUALIZATION
type: Class
subclass of: ResearchRole
definition: Data presentation and visualization

WRITING_ORIGINAL
type: Class
subclass of: ResearchRole
definition: Writing - original draft

AUDIOVISUAL
type: Class
subclass of: DataCiteResourceType
definition: A series of visual representations imparting an impression of motion when shown in succession. May include sound.
examples: video, film, animation

AWARD
type: Class
subclass of: DataCiteResourceType
definition: Funding or support provided to an individual or organization for research, academic work, or professional development.
added version: 4.6
examples: grant award, fellowship, scholarship

BOOK
type: Class
subclass of: DataCiteResourceType
definition: A medium for recording information in the form of writing or images, typically composed of many pages bound together.

BOOK_CHAPTER
type: Class
title: Book Chapter
subclass of: DataCiteResourceType
definition: One of the main divisions of a book.

CITES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A includes B in a citation.
category: citation
inverse: IS_CITED_BY

COLLECTION
type: Class
subclass of: DataCiteResourceType
definition: An aggregation of resources, which may encompass collections of one resource type as well as those of mixed types.

COLLECTS
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A collects B.
category: collection
inverse: IS_COLLECTED_BY

COMPILES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that B is the result of a compile or creation event using A.
category: derivation
inverse: IS_COMPILED_BY

COMPUTATIONAL_NOTEBOOK
type: Class
title: Computational Notebook
subclass of: DataCiteResourceType
definition: A virtual notebook environment used for literate programming, combining code, documentation, and visualizations.
examples: Jupyter notebook, R Markdown, Observable

CONFERENCE_PAPER
type: Class
title: Conference Paper
subclass of: DataCiteResourceType
definition: Article written with the goal of being accepted to a conference.

CONFERENCE_PROCEEDING
type: Class
title: Conference Proceeding
subclass of: DataCiteResourceType
definition: Collection of academic papers published in the context of an academic conference.

CONTACT_PERSON
type: Class
title: Contact Person
subclass of: DataCiteContributorType
definition: Person with knowledge of how to access, troubleshoot, or otherwise field issues related to the resource.
category: support

CONTINUES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A is a continuation of the work B.
category: continuation
inverse: IS_CONTINUED_BY

DATA_COLLECTOR
type: Class
title: Data Collector
subclass of: DataCiteContributorType
definition: Person or institution responsible for finding, gathering, or collecting data under the guidelines of the author(s) or Principal Investigator (PI).
category: data_work

DATA_CURATOR
type: Class
title: Data Curator
subclass of: DataCiteContributorType
definition: Person tasked with reviewing, enhancing, cleaning, or standardizing metadata and the associated data submitted for storage, use, and maintenance within a repository.
category: data_work

DATA_MANAGER
type: Class
title: Data Manager
subclass of: DataCiteContributorType
definition: Person or organization responsible for maintaining the finished resource, including data quality, access permissions, and long-term availability.
category: data_work

DATA_PAPER
type: Class
title: Data Paper
subclass of: DataCiteResourceType
definition: A scholarly publication describing a dataset, intended to facilitate its discovery, interpretation, and reuse.

DATASET
type: Class
subclass of: DataCiteResourceType
definition: Data encoded in a defined structure. May include tables, databases, or other structured data.

DESCRIBES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A describes B.
category: description
inverse: IS_DESCRIBED_BY

DISSERTATION
type: Class
subclass of: DataCiteResourceType
definition: A written essay, treatise, or thesis, especially one written by a candidate for a doctoral degree.

DISTRIBUTOR
type: Class
subclass of: DataCiteContributorType
definition: Institution tasked with responsibility to generate or disseminate copies of the resource in either electronic or print form.
category: dissemination

DOCUMENTS
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A is documentation about/explaining B.
category: documentation
inverse: IS_DOCUMENTED_BY

EDITOR
type: Class
subclass of: DataCiteContributorType
definition: A person who oversees the details related to the publication format of the resource.
category: editorial

EVENT
type: Class
subclass of: DataCiteResourceType
definition: A non-persistent, time-based occurrence. May be planned or unplanned.
examples: conference, workshop, exhibition

HAS_METADATA
type: Class
title: Has Metadata
subclass of: DataCiteRelationType
definition: Indicates that resource A has additional metadata B.
category: metadata
inverse: IS_METADATA_FOR

HAS_PART
type: Class
title: Has Part
subclass of: DataCiteRelationType
definition: Indicates that A includes the part B.
category: partonomy
inverse: IS_PART_OF

HAS_TRANSLATION
type: Class
title: Has Translation
subclass of: DataCiteRelationType
definition: Indicates that A has a translation B.
added version: 4.6
category: translation
inverse: IS_TRANSLATION_OF

HAS_VERSION
type: Class
title: Has Version
subclass of: DataCiteRelationType
definition: Indicates that A has a version B.
category: versioning
inverse: IS_VERSION_OF

HOSTING_INSTITUTION
type: Class
title: Hosting Institution
subclass of: DataCiteContributorType
definition: Typically, the organization allowing the resource to be available on the internet through the provision of its hardware, software, or operating support.
category: infrastructure

IMAGE
type: Class
subclass of: DataCiteResourceType
definition: A visual representation other than text, including photographs, diagrams, illustrations, and other static visual works.

INSTRUMENT
type: Class
subclass of: DataCiteResourceType
definition: A device, tool, or apparatus used to obtain, measure, and/or analyze data.
examples: microscope, telescope, sensor, spectrometer

INTERACTIVE_RESOURCE
type: Class
title: Interactive Resource
subclass of: DataCiteResourceType
definition: A resource requiring interaction from the user to be understood, executed, or experienced.
examples: web application, game, simulation

IS_CITED_BY
type: Class
title: Is Cited By
subclass of: DataCiteRelationType
definition: Indicates that B includes A in a citation.
category: citation
inverse: CITES

IS_COLLECTED_BY
type: Class
title: Is Collected By
subclass of: DataCiteRelationType
definition: Indicates that A is collected by B.
category: collection
inverse: COLLECTS

IS_COMPILED_BY
type: Class
title: Is Compiled By
subclass of: DataCiteRelationType
definition: Indicates that B is used to compile or create A.
category: derivation
inverse: COMPILES

IS_CONTINUED_BY
type: Class
title: Is Continued By
subclass of: DataCiteRelationType
definition: Indicates that A is continued by the work B.
category: continuation
inverse: CONTINUES

IS_DERIVED_FROM
type: Class
title: Is Derived From
subclass of: DataCiteRelationType
definition: Indicates that B is a source upon which A is based.
category: derivation
inverse: IS_SOURCE_OF

IS_DESCRIBED_BY
type: Class
title: Is Described By
subclass of: DataCiteRelationType
definition: Indicates that A is described by B.
category: description
inverse: DESCRIBES

IS_DOCUMENTED_BY
type: Class
title: Is Documented By
subclass of: DataCiteRelationType
definition: Indicates that B is documentation about/explaining A.
category: documentation
inverse: DOCUMENTS

IS_IDENTICAL_TO
type: Class
title: Is Identical To
subclass of: DataCiteRelationType
definition: Indicates that A is identical to B, for use when there is a need to register two separate instances of the same resource.
category: identity

IS_METADATA_FOR
type: Class
title: Is Metadata For
subclass of: DataCiteRelationType
definition: Indicates that additional metadata A describes resource B.
category: metadata
inverse: HAS_METADATA

IS_NEW_VERSION_OF
type: Class
title: Is New Version Of
subclass of: DataCiteRelationType
definition: Indicates that A is a new edition of B, where the new edition has been modified or updated.
category: versioning
inverse: IS_PREVIOUS_VERSION_OF

IS_OBSOLETED_BY
type: Class
title: Is Obsoleted By
subclass of: DataCiteRelationType
definition: Indicates that A is replaced by B.
category: obsolescence
inverse: OBSOLETES

IS_ORIGINAL_FORM_OF
type: Class
title: Is Original Form Of
subclass of: DataCiteRelationType
definition: Indicates that A is the original form of B.
category: form
inverse: IS_VARIANT_FORM_OF

IS_PART_OF
type: Class
title: Is Part Of
subclass of: DataCiteRelationType
definition: Indicates that A is a portion of B. May be used for elements of a series.
category: partonomy
inverse: HAS_PART

IS_PREVIOUS_VERSION_OF
type: Class
title: Is Previous Version Of
subclass of: DataCiteRelationType
definition: Indicates that A is a previous edition of B.
category: versioning
inverse: IS_NEW_VERSION_OF

IS_PUBLISHED_IN
type: Class
title: Is Published In
subclass of: DataCiteRelationType
definition: Indicates that A is published inside B, but is independent of other things published inside of B.
category: publication

IS_REFERENCED_BY
type: Class
title: Is Referenced By
subclass of: DataCiteRelationType
definition: Indicates that A is used as a source of information by B.
category: reference
inverse: REFERENCES

IS_REQUIRED_BY
type: Class
title: Is Required By
subclass of: DataCiteRelationType
definition: Indicates that A is required by B.
category: dependency
inverse: REQUIRES

IS_REVIEWED_BY
type: Class
title: Is Reviewed By
subclass of: DataCiteRelationType
definition: Indicates that A is reviewed by B.
category: review
inverse: REVIEWS

IS_SOURCE_OF
type: Class
title: Is Source Of
subclass of: DataCiteRelationType
definition: Indicates that A is a source upon which B is based.
category: derivation
inverse: IS_DERIVED_FROM

IS_SUPPLEMENT_TO
type: Class
title: Is Supplement To
subclass of: DataCiteRelationType
definition: Indicates that A is a supplement to B.
category: supplementary
inverse: IS_SUPPLEMENTED_BY

IS_SUPPLEMENTED_BY
type: Class
title: Is Supplemented By
subclass of: DataCiteRelationType
definition: Indicates that B is a supplement to A.
category: supplementary
inverse: IS_SUPPLEMENT_TO

IS_TRANSLATION_OF
type: Class
title: Is Translation Of
subclass of: DataCiteRelationType
definition: Indicates that A is a translation of B.
added version: 4.6
category: translation
inverse: HAS_TRANSLATION

IS_VARIANT_FORM_OF
type: Class
title: Is Variant Form Of
subclass of: DataCiteRelationType
definition: Indicates that A is a variant or different form of B.
category: form
inverse: IS_ORIGINAL_FORM_OF

IS_VERSION_OF
type: Class
title: Is Version Of
subclass of: DataCiteRelationType
definition: Indicates that A is a version of B.
category: versioning
inverse: HAS_VERSION

JOURNAL
type: Class
subclass of: DataCiteResourceType
definition: A scholarly publication consisting of articles that is published regularly throughout the year.

JOURNAL_ARTICLE
type: Class
title: Journal Article
subclass of: DataCiteResourceType
definition: A written composition on a topic of interest, which forms a separate part of a journal.

MODEL
type: Class
subclass of: DataCiteResourceType
definition: An abstract, conceptual, graphical, mathematical, or visualization model that represents empirical objects, phenomena, or processes.
examples: 3D model, statistical model, simulation model

OBSOLETES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A replaces B.
category: obsolescence
inverse: IS_OBSOLETED_BY

OUTPUT_MANAGEMENT_PLAN
type: Class
title: Output Management Plan
subclass of: DataCiteResourceType
alternative label: DMP
alternative label: Data Management Plan
definition: A formal document that outlines how research outputs are to be handled during and after a research project.

PEER_REVIEW
type: Class
title: Peer Review
subclass of: DataCiteResourceType
definition: Evaluation of scientific, academic, or professional work by others working in the same field.

PHYSICAL_OBJECT
type: Class
title: Physical Object
subclass of: DataCiteResourceType
definition: A physical object or substance, including artifacts, specimens, samples, and material objects.
examples: fossil, artifact, tissue sample, mineral specimen

PREPRINT
type: Class
subclass of: DataCiteResourceType
definition: A version of a scholarly or scientific paper that precedes formal peer review and publication in a journal.

PRODUCER
type: Class
subclass of: DataCiteContributorType
definition: Person or organization responsible for the artistic and technical aspects of a resource, typically in audiovisual or media contexts.
category: production

PROJECT
type: Class
subclass of: DataCiteResourceType
definition: A planned endeavor or activity, frequently collaborative, intended to achieve a particular aim.
added version: 4.6

PROJECT_LEADER
type: Class
title: Project Leader
subclass of: DataCiteContributorType
alternative label: PI
alternative label: Principal Investigator
definition: Person officially designated as head of a project team or sub-project team instrumental in the work necessary to the development of the resource.
category: leadership

PROJECT_MANAGER
type: Class
title: Project Manager
subclass of: DataCiteContributorType
definition: Person officially designated as manager of a project, responsible for day-to-day management activities.
category: leadership

PROJECT_MEMBER
type: Class
title: Project Member
subclass of: DataCiteContributorType
definition: Person on the membership list of a designated project or project team.
category: team

REFERENCES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that B is used as a source of information for A.
category: reference
inverse: IS_REFERENCED_BY

REGISTRATION_AGENCY
type: Class
title: Registration Agency
subclass of: DataCiteContributorType
definition: Institution or organization officially appointed by a Registration Authority to handle specific tasks within a defined area of responsibility.
category: governance
examples: DataCite member organizations

REGISTRATION_AUTHORITY
type: Class
title: Registration Authority
subclass of: DataCiteContributorType
definition: A standards-setting body from which Registration Agencies obtain their official recognition and guidance.
category: governance
examples: International DOI Foundation

RELATED_PERSON
type: Class
title: Related Person
subclass of: DataCiteContributorType
definition: A person without a specifically defined role in the development of the resource, but who is someone the author wishes to recognize.
category: acknowledgment

REPORT
type: Class
subclass of: DataCiteResourceType
definition: A document that presents information in an organized format for a specific audience and purpose.

REQUIRES
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A requires B.
category: dependency
inverse: IS_REQUIRED_BY

RESEARCH_GROUP
type: Class
title: Research Group
subclass of: DataCiteContributorType
definition: A group of individuals with a common research focus, typically within a lab, department, or division.
category: team

RESEARCHER
type: Class
subclass of: DataCiteContributorType
definition: A person involved in analyzing data or the results of an experiment or formal study.
category: research

REVIEWS
type: Class
subclass of: DataCiteRelationType
definition: Indicates that A is a review of B.
category: review
inverse: IS_REVIEWED_BY

RIGHTS_HOLDER
type: Class
title: Rights Holder
subclass of: DataCiteContributorType
definition: Person or institution owning or managing property rights, including intellectual property rights, over the resource.
category: legal

SERVICE
type: Class
subclass of: DataCiteResourceType
definition: An organized system of apparatus, appliances, staff, etc., for supplying some function required by end users.
examples: API, web service, data service

SOFTWARE
type: Class
subclass of: DataCiteResourceType
definition: A computer program other than a computational notebook, in either source code (text) or compiled form.

SOUND
type: Class
subclass of: DataCiteResourceType
definition: A resource primarily intended to be heard, including music, speech, and other audio recordings.

SPONSOR
type: Class
subclass of: DataCiteContributorType
definition: Person or organization that issued a contract or under the auspices of which a work has been written, printed, published, developed, etc.
category: funding

STANDARD
type: Class
subclass of: DataCiteResourceType
definition: Something established by authority, custom, or general consent as a model, example, or point of reference.
examples: ISO standard, data format specification

STUDY_REGISTRATION
type: Class
title: Study Registration
subclass of: DataCiteResourceType
definition: A detailed, time-stamped description of a research plan, often openly shared in a registry or repository.
examples: clinical trial registration, pre-registration

SUPERVISOR
type: Class
subclass of: DataCiteContributorType
definition: Designated administrator overseeing one or more groups or teams working to produce the resource.
category: leadership

TEXT
type: Class
subclass of: DataCiteResourceType
definition: A resource consisting primarily of words for reading that is not covered by any other textual resource type.

TRANSLATOR
type: Class
subclass of: DataCiteContributorType
definition: Person, organization, or automated system responsible for rendering the content of a resource from one language into another.
added version: 4.6
category: translation

WORK_PACKAGE_LEADER
type: Class
title: Work Package Leader
subclass of: DataCiteContributorType
definition: A Work Package is a recognized data product, and the Work Package Leader ensures the comprehensive contents, availability, and quality of the work package.
category: leadership

WORKFLOW
type: Class
subclass of: DataCiteResourceType
definition: A structured series of steps which can be executed to produce a final outcome, often automated.
examples: bioinformatics pipeline, ETL workflow, analysis script

OXIDOREDUCTASE
type: Class
title: Oxidoreductases
subclass of: EnzymeClassEnum
definition: Catalyzes oxidation-reduction reactions
EC class: 1
examples: dehydrogenases, oxidases

TRANSFERASE
type: Class
title: Transferases
subclass of: EnzymeClassEnum
definition: Catalyzes group transfer reactions
EC class: 2
examples: kinases, transaminases

HYDROLASE
type: Class
title: Hydrolases
subclass of: EnzymeClassEnum
definition: Catalyzes hydrolysis reactions
EC class: 3
examples: proteases, lipases

LYASE
type: Class
title: Lyases
subclass of: EnzymeClassEnum
definition: Catalyzes non-hydrolytic additions/removals
EC class: 4
examples: decarboxylases, aldolases

ISOMERASE
type: Class
title: Isomerases
subclass of: EnzymeClassEnum
definition: Catalyzes isomerization reactions
EC class: 5
examples: racemases, epimerases

LIGASE
type: Class
title: Ligases
subclass of: EnzymeClassEnum
definition: Catalyzes formation of bonds with ATP
EC class: 6
examples: synthetases, carboxylases

TRANSLOCASE
type: Class
title: Translocases
subclass of: EnzymeClassEnum
definition: Catalyzes movement across membranes
EC class: 7
examples: ATPases, ion pumps

GA4GH
type: Class
title: Global Alliance for Genomics and Health
subclass of: ValueSetStewardEnum
definition: International consortium developing standards for responsible sharing of genomic and health-related data. Develops standards including Phenopackets, VRS, DRS, and Beacon.
established: 2013
headquarters: Multiple host institutions

GENE_ONTOLOGY_CONSORTIUM
type: Class
title: Gene Ontology Consortium
subclass of: ValueSetStewardEnum
alternative label: GO Consortium
alternative label: GOC
definition: International consortium developing and maintaining the Gene Ontology, the world's largest source of information on gene function. Provides GO annotations and the GO ontology itself.
established: 1998

GENOMIC_STANDARDS_CONSORTIUM
type: Class
title: Genomic Standards Consortium
subclass of: ValueSetStewardEnum
alternative label: GSC
definition: Open-membership community developing standards for describing genomes, metagenomes, and related data. Develops MIxS checklists and related metadata standards.
established: 2005

VALUESETS_PROJECT
type: Class
title: Valuesets Project
subclass of: ValueSetStewardEnum
alternative label: LinkML Valuesets
definition: The valuesets repository itself, for value sets that are community contributions without a specific external steward. Use sparingly; prefer identifying an appropriate domain consortium.
website: https://w3id.org/valuesets/

OXYGEN_SATURATION
type: Class
title: Blood oxygen saturation
subclass of: VitalSignEnum
normal range: 95-100%
units: %

PAIN_SCALE
type: Class
title: Pain level (0-10)
subclass of: VitalSignEnum
scale: 0-10
type: subjective

TEMPERATURE
type: Class
title: Body temperature
subclass of: VitalSignEnum
normal range: 36.5-37.5°C
units: °C or °F

BLOOD_PRESSURE_DIASTOLIC
type: Class
title: Diastolic blood pressure
subclass of: VitalSignEnum
normal range: <80 mmHg
units: mmHg

BLOOD_PRESSURE_SYSTOLIC
type: Class
title: Systolic blood pressure
subclass of: VitalSignEnum
normal range: <120 mmHg
units: mmHg

HEART_RATE
type: Class
title: Heart beats per minute
subclass of: VitalSignEnum
normal range: 60-100 bpm
units: beats/min

RESPIRATORY_RATE
type: Class
title: Breaths per minute
subclass of: VitalSignEnum
normal range: 12-20 breaths/min
units: breaths/min

MONARCH_INITIATIVE
type: Class
title: Monarch Initiative
subclass of: ValueSetStewardEnum
alternative label: Monarch
definition: International consortium integrating genotype-phenotype data across species. Develops and maintains ontologies including HPO, Mondo, and Upheno, and provides data integration services.

OBO_FOUNDRY
type: Class
title: OBO Foundry
subclass of: ValueSetStewardEnum
alternative label: Open Biological and Biomedical Ontologies Foundry
definition: Collaborative effort to develop interoperable ontologies for the life sciences. Coordinates ontology development and establishes principles for ontology best practices.
established: 2007

OHDSI
type: Class
subclass of: ValueSetStewardEnum
alternative label: Observational Health Data Sciences and Informatics
definition: Observational Health Data Sciences and Informatics program. International collaborative developing open-source analytics solutions for observational health data. Maintains the OMOP Common Data Model.
coordinating center: Columbia University
established: 2014

PHENOPACKETS
type: Class
title: Phenopackets
subclass of: ValueSetStewardEnum
alternative label: GA4GH Phenopackets
definition: GA4GH work stream developing standards for sharing disease and phenotype information. Develops the Phenopacket Schema for representing clinical and phenotypic data.
parent organization: GA4GH

NLM
type: Class
title: United States National Library of Medicine
subclass of: NIHInstituteCenterEnum
alternative label: National Library of Medicine
definition: World's largest biomedical library and NIH component
established: 1956
parent organization: National Institutes of Health
website: https://www.nlm.nih.gov/

NIDDK
type: Class
title: National Institute of Diabetes and Digestive and Kidney Diseases
subclass of: NIHInstituteCenterEnum
definition: NIH institute for diabetes, digestive, and kidney diseases research
established: 1950
parent organization: National Institutes of Health
website: https://www.niddk.nih.gov/

NHGRI
type: Class
title: National Human Genome Research Institute
subclass of: NIHInstituteCenterEnum
definition: NIH institute for genomics and genetics research
established: 1989
parent organization: National Institutes of Health
website: https://www.genome.gov/

IAEA
type: Class
title: International Atomic Energy Agency
subclass of: UNSpecializedAgencyEnum
definition: International organization promoting peaceful use of nuclear energy
established: 1957
headquarters: Vienna, Austria
website: https://www.iaea.org/

NIEHS
type: Class
title: National Institute of Environmental Health Sciences
subclass of: NIHInstituteCenterEnum
definition: NIH institute for environmental health sciences research
established: 1966
parent organization: National Institutes of Health
website: https://www.niehs.nih.gov/

IDAHO_NATIONAL_LABORATORY
type: Class
title: Idaho National Laboratory
subclass of: USDOENationalLaboratoryEnum
definition: Nuclear energy research and national security laboratory
established: 1949
location: Idaho Falls, Idaho
stewarding office: Office of Nuclear Energy
website: https://inl.gov/

WMO
type: Class
title: World Meteorological Organization
subclass of: UNSpecializedAgencyEnum
definition: UN agency for weather, climate and water resources
established: 1950
headquarters: Geneva, Switzerland
website: https://public.wmo.int/

NHLBI
type: Class
title: National Heart Lung and Blood Institute
subclass of: NIHInstituteCenterEnum
alternative label: National Heart, Lung, and Blood Institute
definition: NIH institute for heart, lung, and blood diseases research
established: 1948
parent organization: National Institutes of Health
website: https://www.nhlbi.nih.gov/

UNEP
type: Class
title: United Nations Environment Programme
subclass of: UNSpecializedAgencyEnum
definition: UN program coordinating environmental activities
established: 1972
headquarters: Nairobi, Kenya
website: https://www.unep.org/

SANDIA_NATIONAL_LABORATORIES
type: Class
title: Sandia National Laboratories
subclass of: USDOENationalLaboratoryEnum
alternative label: SNL
alternative label: Sandia
definition: Multimission laboratory for national security and technology innovation
established: 1949
location: Albuquerque, New Mexico and Livermore, California
stewarding office: National Nuclear Security Administration
website: https://www.sandia.gov/

DOE
type: Class
title: United States Department of Energy
subclass of: USFederalFundingAgencyEnum
alternative label: Department of Energy
alternative label: U.S. Department of Energy
definition: Federal department overseeing energy policy and nuclear weapons program
established: 1977
website: https://www.energy.gov/

NIH
type: Class
title: National Institutes of Health
subclass of: USFederalFundingAgencyEnum
definition: Primary federal agency for biomedical and public health research
established: 1887
parent department: Department of Health and Human Services
website: https://www.nih.gov/

LOS_ALAMOS_NATIONAL_LABORATORY
type: Class
title: Los Alamos National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: LANL
definition: Multidisciplinary research institution for national security
established: 1943
location: Los Alamos, New Mexico
stewarding office: National Nuclear Security Administration
website: https://www.lanl.gov/

WHO
type: Class
title: World Health Organization
subclass of: UNSpecializedAgencyEnum
definition: UN agency for international public health
established: 1948
headquarters: Geneva, Switzerland
website: https://www.who.int/

IEEE
type: Class
title: Institute of Electrical and Electronics Engineers
subclass of: StandardsOrganizationEnum
definition: Professional association for electronic and electrical engineering
established: 1963
headquarters: New York, USA
website: https://www.ieee.org/

OAK_RIDGE_NATIONAL_LABORATORY
type: Class
title: Oak Ridge National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: ORNL
definition: Multidisciplinary science and technology laboratory
established: 1943
location: Oak Ridge, Tennessee
stewarding office: Office of Science
website: https://www.ornl.gov/

NINDS
type: Class
title: National Institute of Neurological Disorders and Stroke
subclass of: NIHInstituteCenterEnum
definition: NIH institute for neurological disorders research
established: 1950
parent organization: National Institutes of Health
website: https://www.ninds.nih.gov/

NATIONAL_ENERGY_TECHNOLOGY_LABORATORY
type: Class
title: National Energy Technology Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: NETL
definition: Federal research laboratory focused on energy and environmental technology
established: 1910
location: Pittsburgh, Pennsylvania and Morgantown, West Virginia
stewarding office: Office of Fossil Energy and Carbon Management
website: https://www.netl.doe.gov/

FERMI_NATIONAL_ACCELERATOR_LABORATORY
type: Class
title: Fermi National Accelerator Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: Fermilab
definition: Particle physics and accelerator research laboratory
established: 1967
location: Batavia, Illinois
stewarding office: Office of Science
website: https://www.fnal.gov/

NSF
type: Class
title: U.S. National Science Foundation
subclass of: USFederalFundingAgencyEnum
alternative label: National Science Foundation
definition: Federal agency supporting fundamental research and education in non-medical fields
established: 1950
website: https://www.nsf.gov/

NASA
type: Class
title: National Aeronautics and Space Administration
subclass of: USFederalFundingAgencyEnum
definition: Federal agency responsible for civil space program and aeronautics research
established: 1958
website: https://www.nasa.gov/

EMBL_EBI
type: Class
title: European Bioinformatics Institute
subclass of: ValueSetStewardEnum
alternative label: EBI
alternative label: EMBL-EBI
definition: EMBL's European Bioinformatics Institute, a global leader in bioinformatics services, databases, and tools. Hosts major resources including UniProt, Ensembl, and the Ontology Lookup Service.
location: Hinxton, UK
parent organization: European Molecular Biology Laboratory
website: https://www.ebi.ac.uk/

USDA_ARS
type: Class
title: Agricultural Research Service
subclass of: USFederalFundingAgencyEnum
alternative label: USDA ARS
definition: Principal research agency of the U.S. Department of Agriculture
established: 1953
parent department: Department of Agriculture
website: https://www.ars.usda.gov/

BROOKHAVEN_NATIONAL_LABORATORY
type: Class
title: Brookhaven National Laboratory
subclass of: USDOENationalLaboratoryEnum
definition: Research center for nuclear and high-energy physics
established: 1947
location: Upton, New York
stewarding office: Office of Science
website: https://www.bnl.gov/

LAWRENCE_BERKELEY_NATIONAL_LABORATORY
type: Class
title: Lawrence Berkeley National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: Berkeley Lab
alternative label: LBNL
definition: Multidisciplinary research laboratory
established: 1931
location: Berkeley, California
stewarding office: Office of Science
website: https://www.lbl.gov/

NCBI
type: Class
title: National Center for Biotechnology Information
subclass of: ValueSetStewardEnum
definition: Part of the United States National Library of Medicine. Develops databases and tools for molecular biology including GenBank, PubMed, and the NCBI Taxonomy.
location: Bethesda, MD, USA
parent organization: National Library of Medicine
website: https://www.ncbi.nlm.nih.gov/

NCI
type: Class
title: National Cancer Institute
subclass of: NIHInstituteCenterEnum
definition: NIH institute for cancer research and training
established: 1937
parent organization: National Institutes of Health
website: https://www.cancer.gov/

THOMAS_JEFFERSON_NATIONAL_ACCELERATOR_FACILITY
type: Class
title: Thomas Jefferson National Accelerator Facility
subclass of: USDOENationalLaboratoryEnum
alternative label: JLab
alternative label: Jefferson Lab
definition: Nuclear physics research laboratory with particle accelerator
established: 1984
location: Newport News, Virginia
stewarding office: Office of Science
website: https://www.jlab.org/

NOAA
type: Class
title: National Oceanic and Atmospheric Administration
subclass of: USFederalFundingAgencyEnum
definition: Federal agency focused on ocean, atmosphere, and coastal research
established: 1970
parent department: Department of Commerce
website: https://www.noaa.gov/

USGS
type: Class
title: United States Geological Survey
subclass of: USFederalFundingAgencyEnum
definition: Federal agency for earth science research and monitoring
established: 1879
parent department: Department of the Interior
website: https://www.usgs.gov/

NATIONAL_RENEWABLE_ENERGY_LABORATORY
type: Class
title: National Renewable Energy Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: NREL
definition: Research and development laboratory focused on renewable energy and energy efficiency
established: 1977
location: Golden, Colorado
stewarding office: Office of Energy Efficiency and Renewable Energy
website: https://www.nrel.gov/

EPA
type: Class
title: Environmental Protection Agency
subclass of: USFederalFundingAgencyEnum
alternative label: U.S. Environmental Protection Agency
definition: Federal agency protecting human health and the environment
established: 1970
website: https://www.epa.gov/

PRINCETON_PLASMA_PHYSICS_LABORATORY
type: Class
title: Princeton Plasma Physics Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: PPPL
definition: Plasma physics and fusion energy research laboratory
established: 1951
location: Princeton, New Jersey
stewarding office: Office of Science
website: https://www.pppl.gov/

NEI
type: Class
title: National Eye Institute
subclass of: NIHInstituteCenterEnum
definition: NIH institute for vision and eye disease research
established: 1968
parent organization: National Institutes of Health
website: https://www.nei.nih.gov/

AMES_LABORATORY
type: Class
title: Ames National Laboratory
subclass of: USDOENationalLaboratoryEnum
definition: National laboratory focused on materials science and chemistry research
established: 1947
location: Ames, Iowa
stewarding office: Office of Science
website: https://www.ameslab.gov/

LAWRENCE_LIVERMORE_NATIONAL_LABORATORY
type: Class
title: Lawrence Livermore National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: LLNL
definition: National security laboratory focused on nuclear weapons and advanced technology
established: 1952
location: Livermore, California
stewarding office: National Nuclear Security Administration
website: https://www.llnl.gov/

NIAID
type: Class
title: National Institute of Allergy and Infectious Diseases
subclass of: NIHInstituteCenterEnum
definition: NIH institute for infectious, immunologic, and allergic diseases research
established: 1948
parent organization: National Institutes of Health
website: https://www.niaid.nih.gov/

DOD
type: Class
title: United States Department of Defense
subclass of: USFederalFundingAgencyEnum
alternative label: Department of Defense
alternative label: U.S. Department of Defense
definition: Federal department responsible for military research and development
established: 1947
website: https://www.defense.gov/

NIA
type: Class
title: National Institute on Aging
subclass of: NIHInstituteCenterEnum
definition: NIH institute for aging research
established: 1974
parent organization: National Institutes of Health
website: https://www.nia.nih.gov/

UNESCO
type: Class
subclass of: UNSpecializedAgencyEnum
alternative label: United Nations Educational, Scientific and Cultural Organization
definition: UN Educational, Scientific and Cultural Organization
established: 1945
headquarters: Paris, France
website: https://www.unesco.org/

NIGMS
type: Class
title: National Institute of General Medical Sciences
subclass of: NIHInstituteCenterEnum
definition: NIH institute supporting basic biomedical research
established: 1962
parent organization: National Institutes of Health
website: https://www.nigms.nih.gov/

NIMH
type: Class
title: National Institute of Mental Health
subclass of: NIHInstituteCenterEnum
definition: NIH institute for mental health research
established: 1949
parent organization: National Institutes of Health
website: https://www.nimh.nih.gov/

ARGONNE_NATIONAL_LABORATORY
type: Class
title: Argonne National Laboratory
subclass of: USDOENationalLaboratoryEnum
definition: Multidisciplinary science and engineering research center
established: 1946
location: Lemont, Illinois
stewarding office: Office of Science
website: https://www.anl.gov/

SLAC_NATIONAL_ACCELERATOR_LABORATORY
type: Class
title: SLAC National Accelerator Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: SLAC
definition: Particle physics and photon science research laboratory
established: 1962
location: Menlo Park, California
stewarding office: Office of Science
website: https://www6.slac.stanford.edu/

PACIFIC_NORTHWEST_NATIONAL_LABORATORY
type: Class
title: Pacific Northwest National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: PNNL
definition: Research laboratory focused on energy, environment, and national security
established: 1965
location: Richland, Washington
stewarding office: Office of Science
website: https://www.pnnl.gov/

SAVANNAH_RIVER_NATIONAL_LABORATORY
type: Class
title: Savannah River National Laboratory
subclass of: USDOENationalLaboratoryEnum
alternative label: SRNL
definition: Applied research laboratory for environmental and national security missions
established: 1951
location: Aiken, South Carolina
stewarding office: Office of Environmental Management
website: https://www.srnl.gov/

NIST
type: Class
title: National Institute of Standards and Technology
subclass of: USFederalFundingAgencyEnum
definition: Federal agency promoting innovation and industrial competitiveness
established: 1901
parent department: Department of Commerce
website: https://www.nist.gov/

AGPL_3_0
type: Class
subclass of: LicenseType
definition: GNU Affero General Public License v3.0

BSD_2_CLAUSE
type: Class
subclass of: LicenseType
definition: BSD 2-Clause License

CC_BY_NC_4_0
type: Class
subclass of: LicenseType
definition: Creative Commons Attribution-NonCommercial 4.0

CC_BY_NC_SA_4_0
type: Class
subclass of: LicenseType
definition: Creative Commons Attribution-NonCommercial-ShareAlike 4.0

CC_BY_ND_4_0
type: Class
subclass of: LicenseType
definition: Creative Commons Attribution-NoDerivatives 4.0

GPL_2_0
type: Class
subclass of: LicenseType
definition: GNU General Public License v2.0

GPL_3_0
type: Class
subclass of: LicenseType
definition: GNU General Public License v3.0

GPL_3_0
type: Class
title: GPL-3.0
subclass of: MLLicenseType
definition: GNU General Public License v3.0
copyleft: true
osi approved: true

ISC
type: Class
subclass of: LicenseType
definition: ISC License

LGPL_2_1
type: Class
subclass of: LicenseType
definition: GNU Lesser General Public License v2.1

LGPL_3_0
type: Class
subclass of: LicenseType
definition: GNU Lesser General Public License v3.0

MPL_2_0
type: Class
subclass of: LicenseType
definition: Mozilla Public License 2.0

UNLICENSE
type: Class
subclass of: LicenseType
definition: The Unlicense

DBA
type: Class
subclass of: AcademicDegree
definition: Doctor of Business Administration
level: doctoral

MFA
type: Class
subclass of: AcademicDegree
definition: Master of Fine Arts
level: graduate

MPHIL
type: Class
subclass of: AcademicDegree
definition: Master of Philosophy
level: graduate

POSTDOC
type: Class
subclass of: AcademicDegree
definition: Postdoctoral researcher
level: postdoctoral

PSYD
type: Class
subclass of: AcademicDegree
definition: Doctor of Psychology
level: doctoral

AcademicDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for academic value sets
in scheme: merged

EMBARGOED
type: Class
subclass of: AccessRights
definition: The resource is temporarily restricted and will become publicly available after a specific date or event.
common in: academic publishing, research data

SENSITIVE
type: Class
subclass of: AccessRights
definition: The resource contains sensitive information requiring special handling or access controls.
examples: PII, health data, classified information

BINDER_JETTING
type: Class
title: Binder Jetting
subclass of: AdditiveManufacturingEnum
definition: Powder bed with liquid binder

DED
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: Directed Energy Deposition
definition: Directed Energy Deposition

EBM
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: Electron Beam Melting
definition: Electron Beam Melting

FDM
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: FFF
alternative label: Fused Filament Fabrication
definition: Fused Deposition Modeling

MATERIAL_JETTING
type: Class
title: Material Jetting
subclass of: AdditiveManufacturingEnum
alternative label: PolyJet
definition: Droplet deposition of materials

SLA
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: Stereolithography
definition: Stereolithography

SLM
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: Selective Laser Melting
definition: Selective Laser Melting

SLS
type: Class
subclass of: AdditiveManufacturingEnum
alternative label: Selective Laser Sintering
definition: Selective Laser Sintering

ANCHOR
type: Class
subclass of: AgitationTypeEnum
definition: Anchor impeller
type: Close clearance
viscous fluids: true

HELICAL_RIBBON
type: Class
subclass of: AgitationTypeEnum
definition: Helical ribbon impeller
high viscosity: true
type: Close clearance

MAGNETIC_BAR
type: Class
subclass of: AgitationTypeEnum
definition: Magnetic stir bar
scale: Laboratory
volume: <5 L

MARINE_PROPELLER
type: Class
subclass of: AgitationTypeEnum
definition: Marine propeller
low shear: true
type: Axial flow

NO_AGITATION
type: Class
subclass of: AgitationTypeEnum
definition: No mechanical agitation
mixing: Gas sparging or static

ORBITAL_SHAKING
type: Class
subclass of: AgitationTypeEnum
definition: Orbital shaking
application: Shake flasks
type: Platform shaker

PITCHED_BLADE
type: Class
subclass of: AgitationTypeEnum
definition: Pitched blade turbine
angle: 45 degrees
type: Axial flow

RUSHTON_TURBINE
type: Class
subclass of: AgitationTypeEnum
definition: Rushton turbine impeller
power number: 5-6
type: Radial flow

ANAPHYLAXIS
type: Class
title: Severe systemic reaction
subclass of: AllergyTypeEnum
severity: life-threatening

CONTACT
type: Class
title: Contact dermatitis
subclass of: AllergyTypeEnum
examples: latex, nickel, poison ivy

ENVIRONMENTAL
type: Class
title: Environmental allergy
subclass of: AllergyTypeEnum
examples: pollen, dust, mold

FOOD
type: Class
title: Food allergy
subclass of: AllergyTypeEnum
common: nuts, shellfish, eggs, milk

INSECT
type: Class
title: Insect sting allergy
subclass of: AllergyTypeEnum
examples: bee, wasp, hornet

B
type: Class
title: Aspartic acid
subclass of: AminoAcidExtendedEnum
alternative label: L-aspartic acid or Asparagine (D or N)
ambiguity: true
represents: D,N
three letter: Asx

GAP
type: Class
title: Gap character
subclass of: AminoAcidExtendedEnum
represents: gap
symbol: -

J
type: Class
title: Leucine
subclass of: AminoAcidExtendedEnum
alternative label: L-leucine or Isoleucine (L or I)
ambiguity: true
represents: L,I
three letter: Xle

STOP
type: Class
title: Translation stop/termination
subclass of: AminoAcidExtendedEnum
represents: stop codon
symbol: *
three letter: Ter

X
type: Class
title: Any amino acid
subclass of: AminoAcidExtendedEnum
ambiguity: true
represents: any
three letter: Xaa

Z
type: Class
title: Glutamic acid
subclass of: AminoAcidExtendedEnum
alternative label: L-glutamic acid or Glutamine (E or Q)
ambiguity: true
represents: E,Q
three letter: Glx

EBV_IMMORTALIZED
type: Class
subclass of: AnalyteTypeEnum
alternative label: EBV Immortalized Normal
definition: DNA/cells from EBV immortalized cell lines

FFPE_DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Formalin-Fixed Paraffin-Embedded DNA
definition: DNA extracted from formalin-fixed paraffin-embedded tissue

FFPE_RNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Formalin-Fixed Paraffin-Embedded RNA
definition: RNA extracted from formalin-fixed paraffin-embedded tissue

GENOMEPLEX_DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: GenomePlex (Rubicon) Amplified DNA
definition: Whole genome amplified DNA using GenomePlex technology

NUCLEI_RNA
type: Class
subclass of: AnalyteTypeEnum
definition: RNA isolated from cell nuclei

REPLI_G_DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Repli-G (Qiagen) DNA
definition: Whole genome amplified DNA using Repli-G technology

REPLI_G_POOLED_DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Repli-G Pooled (Qiagen) DNA
definition: Pooled whole genome amplified DNA using Repli-G

REPLI_G_X_DNA
type: Class
subclass of: AnalyteTypeEnum
alternative label: Repli-G X (Qiagen) DNA
definition: Whole genome amplified DNA using Repli-G X technology

TOTAL_RNA
type: Class
subclass of: AnalyteTypeEnum
definition: Total RNA including all RNA species

BLANK
type: Class
subclass of: AnalyticalControlType
definition: Sample containing only solvent/matrix without analyte

QUALITY_CONTROL
type: Class
subclass of: AnalyticalControlType
definition: Sample with known composition for system performance monitoring

ANTERIOR_TO_POSTERIOR
type: Class
title: Anterior to posterior orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from front to back of an anatomical structure
source: OME NGFF

CAUDAL_TO_CRANIAL
type: Class
title: Caudal to cranial orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from tail to head end of a structure
source: OME NGFF

CAUDAL_TO_ROSTRAL
type: Class
title: Caudal to rostral orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from tail to nasal end, typically for central nervous system
context: central nervous system
source: OME NGFF

CRANIAL_TO_CAUDAL
type: Class
title: Cranial to caudal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from head to tail end of a structure
source: OME NGFF

DISTAL_TO_PROXIMAL
type: Class
title: Distal to proximal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from periphery to body center of a structure
source: OME NGFF

DORSAL_TO_PALMAR
type: Class
title: Dorsal to palmar orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from top/upper to palm of hand
context: hand anatomy
source: OME NGFF

DORSAL_TO_PLANTAR
type: Class
title: Dorsal to plantar orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from top/upper to sole of foot
context: foot anatomy
source: OME NGFF

DORSAL_TO_VENTRAL
type: Class
title: Dorsal to ventral orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from top/upper to belly/lower in an anatomical structure
source: OME NGFF

INFERIOR_TO_SUPERIOR
type: Class
title: Inferior to superior orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from below to above in an anatomical structure
source: OME NGFF

LEFT_TO_RIGHT
type: Class
title: Left to right orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from left to right lateral side of an anatomical structure
source: OME NGFF

PALMAR_TO_DORSAL
type: Class
title: Palmar to dorsal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from palm of hand to top/upper
context: hand anatomy
source: OME NGFF

PLANTAR_TO_DORSAL
type: Class
title: Plantar to dorsal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from sole of foot to top/upper
context: foot anatomy
source: OME NGFF

POSTERIOR_TO_ANTERIOR
type: Class
title: Posterior to anterior orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from back to front of an anatomical structure
source: OME NGFF

PROXIMAL_TO_DISTAL
type: Class
title: Proximal to distal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from body center to periphery of a structure
source: OME NGFF

RIGHT_TO_LEFT
type: Class
title: Right to left orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from right to left lateral side of an anatomical structure
source: OME NGFF

ROSTRAL_TO_CAUDAL
type: Class
title: Rostral to caudal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from nasal to tail end, typically for central nervous system
context: central nervous system
source: OME NGFF

SUPERIOR_TO_INFERIOR
type: Class
title: Superior to inferior orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from above to below in an anatomical structure
source: OME NGFF

VENTRAL_TO_DORSAL
type: Class
title: Ventral to dorsal orientation
subclass of: AnatomicalOrientation
definition: Directional orientation from belly/lower to top/upper in an anatomical structure
source: OME NGFF

OBLIQUE
type: Class
subclass of: AnatomicalPlane
definition: Any plane not parallel to sagittal, coronal, or transverse planes
note: angled section

GRADIAN
type: Class
subclass of: AngleUnitEnum
definition: Gradian/gon
conversion to degree: 0.9
symbol: gon

MINUTE_OF_ARC
type: Class
subclass of: AngleUnitEnum
definition: Minute of arc/arcminute
conversion to degree: 0.0166667
symbol: '

SECOND_OF_ARC
type: Class
subclass of: AngleUnitEnum
definition: Second of arc/arcsecond
conversion to degree: 0.000277778
symbol: "

TURN
type: Class
subclass of: AngleUnitEnum
definition: Turn/revolution
conversion to radian: 6.28319
symbol: turn

BAY
type: Class
subclass of: AnimalCoatColorEnum
definition: Bay (brown with black points)
species: horses

BLACK
type: Class
subclass of: AnimalCoatColorEnum
definition: Black coat
hex: 000000

BRINDLE
type: Class
subclass of: AnimalCoatColorEnum
definition: Brindle pattern (striped)
pattern: striped mixture of colors

BROWN
type: Class
subclass of: AnimalCoatColorEnum
definition: Brown coat
hex: 964B00

CALICO
type: Class
subclass of: AnimalCoatColorEnum
definition: Calico pattern (tri-color)
pattern: tri-color patches
species: primarily cats

CHESTNUT
type: Class
subclass of: AnimalCoatColorEnum
definition: Chestnut/sorrel
hex: CD5C5C
species: horses

CREAM
type: Class
subclass of: AnimalCoatColorEnum
definition: Cream coat
hex: FFFDD0

FAWN
type: Class
subclass of: AnimalCoatColorEnum
definition: Fawn coat
hex: E5AA70

GOLDEN
type: Class
subclass of: AnimalCoatColorEnum
definition: Golden coat
hex: FFD700

GRAY
type: Class
subclass of: AnimalCoatColorEnum
definition: Gray coat
hex: 808080

MERLE
type: Class
subclass of: AnimalCoatColorEnum
definition: Merle pattern (mottled)
pattern: mottled patches

PALOMINO
type: Class
subclass of: AnimalCoatColorEnum
definition: Palomino (golden with white mane)
hex: DEC05F
species: horses

PIEBALD
type: Class
subclass of: AnimalCoatColorEnum
definition: Piebald pattern (patches)
pattern: irregular patches

RED
type: Class
subclass of: AnimalCoatColorEnum
definition: Red/rust coat
hex: B22222

ROAN
type: Class
subclass of: AnimalCoatColorEnum
definition: Roan pattern (mixed white)
pattern: white mixed with base color
species: primarily horses

SPOTTED
type: Class
subclass of: AnimalCoatColorEnum
definition: Spotted pattern
pattern: spots on base color

TABBY
type: Class
subclass of: AnimalCoatColorEnum
definition: Tabby pattern (striped)
pattern: striped or spotted
species: primarily cats

TAN
type: Class
subclass of: AnimalCoatColorEnum
definition: Tan coat
hex: D2B48C

TORTOISESHELL
type: Class
subclass of: AnimalCoatColorEnum
definition: Tortoiseshell pattern
pattern: mottled orange and black
species: primarily cats

WHITE
type: Class
subclass of: AnimalCoatColorEnum
definition: White coat
hex: FFFFFF

AnomalyDetectionEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Anomaly Detection
status: DRAFT
subclass of: BinaryClassificationSchemaEnum
union of: NCIT C14165
union of: ANOMALY
definition: Labels for anomaly detection tasks
in scheme: merged
permissible values: NCIT C14165
permissible values: ANOMALY
source domain: data_science
source schema: binary_classification

ALLUVIAL
type: Class
subclass of: AquiferType
definition: An aquifer composed of unconsolidated alluvial deposits such as sand and gravel deposited by rivers

ARTESIAN
type: Class
subclass of: AquiferType
definition: A confined aquifer in which the hydraulic pressure causes water to rise above the top of the aquifer

CONFINED
type: Class
subclass of: AquiferType
definition: An aquifer bounded above and below by impermeable layers, under pressure greater than atmospheric

FRACTURED_ROCK
type: Class
subclass of: AquiferType
definition: An aquifer in which groundwater flows primarily through fractures in otherwise low-permeability rock

KARST
type: Class
subclass of: AquiferType
broad match: ENVO_00000175
definition: An aquifer in soluble rock such as limestone where flow occurs through dissolution-enlarged conduits and fractures

PERCHED
type: Class
subclass of: AquiferType
definition: A localized unconfined aquifer above the regional water table, supported by a low-permeability layer

SEMI_CONFINED
type: Class
subclass of: AquiferType
definition: An aquifer partially bounded by layers of lower permeability that allow some vertical leakage

UNCONFINED
type: Class
subclass of: AquiferType
definition: An aquifer whose upper boundary is the water table, open to atmospheric pressure

BZIP2
type: Class
subclass of: ArchiveFormatEnum
definition: Bzip2 compression
compression: Burrows-Wheeler
extension: .bz2
mime type: application/x-bzip2

GZIP
type: Class
subclass of: ArchiveFormatEnum
definition: GNU zip
compression: DEFLATE
extension: .gz
mime type: application/gzip

RAR
type: Class
subclass of: ArchiveFormatEnum
definition: RAR archive
extension: .rar
mime type: application/vnd.rar
proprietary: true

SEVEN_ZIP
type: Class
subclass of: ArchiveFormatEnum
definition: 7-Zip archive
compression: LZMA
extension: .7z
mime type: application/x-7z-compressed

TAR
type: Class
subclass of: ArchiveFormatEnum
definition: Tape Archive
compression: none (archive only)
extension: .tar
mime type: application/x-tar

TAR_BZ2
type: Class
subclass of: ArchiveFormatEnum
definition: Bzip2 compressed tar archive
extension: .tar.bz2, .tbz2
mime type: application/x-bzip2

TAR_GZ
type: Class
subclass of: ArchiveFormatEnum
definition: Gzipped tar archive
compression: tar + gzip
extension: .tar.gz, .tgz
mime type: application/x-gtar

TAR_XZ
type: Class
subclass of: ArchiveFormatEnum
definition: XZ compressed tar archive
extension: .tar.xz, .txz
mime type: application/x-xz

XZ
type: Class
subclass of: ArchiveFormatEnum
definition: XZ compression
compression: LZMA2
extension: .xz
mime type: application/x-xz

ZIP
type: Class
subclass of: ArchiveFormatEnum
definition: ZIP archive
compression: DEFLATE
extension: .zip
mime type: application/zip

astro-ph.CO
type: Class
title: Cosmology and Nongalactic Astrophysics
subclass of: ArxivCategory
subclass of: astro-ph
definition: Phenomenology of early universe, cosmic microwave background, cosmological parameters, primordial element abundances.

astro-ph.EP
type: Class
title: Earth and Planetary Astrophysics
subclass of: ArxivCategory
subclass of: astro-ph
definition: Interplanetary medium, planetary physics, terrestrial planets, extrasolar planets, irregular satellites.

astro-ph.GA
type: Class
title: Astrophysics of Galaxies
subclass of: ArxivCategory
subclass of: astro-ph
definition: Phenomena pertaining to galaxies or combinations of galaxies, interstellar medium, star clusters.

astro-ph.HE
type: Class
title: High Energy Astrophysical Phenomena
subclass of: ArxivCategory
subclass of: astro-ph
definition: Cosmic ray production, gamma rays, X-rays, charged particles, supernovae, neutron stars, pulsars.

astro-ph.IM
type: Class
title: Instrumentation and Methods for Astrophysics
subclass of: ArxivCategory
subclass of: astro-ph
definition: Detector and calculation design, space and laboratory observatories, data analysis methods.

astro-ph.SR
type: Class
title: Solar and Stellar Astrophysics
subclass of: ArxivCategory
subclass of: astro-ph
definition: White dwarfs, brown dwarfs, stars, solar system, helioseismology, stellar evolution.

cond-mat.dis-nn
type: Class
title: Disordered Systems and Neural Networks
subclass of: ArxivCategory
subclass of: cond-mat
definition: Glasses and spin glasses; random systems; information theory in physics; neural networks.

cond-mat.mes-hall
type: Class
title: Mesoscale and Nanoscale Physics
subclass of: ArxivCategory
subclass of: cond-mat
definition: Quantum dots and wires, nanotubes, graphene, ballistic transport, mesoscale and nanoscale systems.

cond-mat.mtrl-sci
type: Class
title: Materials Science
subclass of: ArxivCategory
subclass of: cond-mat
definition: Techniques, synthesis, characterization, structure; mechanical and structural phase transitions.

cond-mat.other
type: Class
title: Other Condensed Matter
subclass of: ArxivCategory
subclass of: cond-mat
definition: Work in condensed matter that does not fit into other cond-mat classifications.

cond-mat.quant-gas
type: Class
title: Quantum Gases
subclass of: ArxivCategory
subclass of: cond-mat
definition: Ultracold atomic gases, Bose-Einstein condensation, Feshbach resonances, spinor condensates.

cond-mat.soft
type: Class
title: Soft Condensed Matter
subclass of: ArxivCategory
subclass of: cond-mat
definition: Membranes, emulsions, gels, foams, nematic phases, polymers, liquid crystals.

cond-mat.stat-mech
type: Class
title: Statistical Mechanics
subclass of: ArxivCategory
subclass of: cond-mat
definition: Phase transitions, thermodynamics, field theory, non-equilibrium phenomena, renormalization.

cond-mat.str-el
type: Class
title: Strongly Correlated Electrons
subclass of: ArxivCategory
subclass of: cond-mat
definition: Quantum magnetism, non-Fermi liquid, spin liquids, stripe phases, electron-phonon interactions.

cond-mat.supr-con
type: Class
title: Superconductivity
subclass of: ArxivCategory
subclass of: cond-mat
definition: Superconductivity theory, models, phenomenology, experimental results.

cs.AI
type: Class
title: Artificial Intelligence
subclass of: ArxivCategory
subclass of: cs
definition: Covers all areas of AI except Vision, Robotics, Machine Learning, Multiagent Systems, and NLP. Includes Expert Systems, Theorem Proving, Knowledge Representation, Planning, and Uncertainty in AI.

cs.AR
type: Class
title: Hardware Architecture
subclass of: ArxivCategory
subclass of: cs
definition: Covers systems organization and hardware architecture. Roughly includes material in ACM Subject Class C.0, C.1, and C.5.

cs.CC
type: Class
title: Computational Complexity
subclass of: ArxivCategory
subclass of: cs
definition: Covers models of computation, complexity classes, structural complexity, complexity tradeoffs, upper and lower bounds.

cs.CE
type: Class
title: Computational Engineering, Finance, and Science
subclass of: ArxivCategory
subclass of: cs
definition: Covers applications of computer science to the mathematical modeling of complex systems in science, engineering, and finance.

cs.CG
type: Class
title: Computational Geometry
subclass of: ArxivCategory
subclass of: cs
definition: Geometric algorithms, discrete differential geometry, and directly related problems.

cs.CL
type: Class
title: Computation and Language
subclass of: ArxivCategory
subclass of: cs
definition: Covers natural language processing. Includes computational linguistics, speech processing, text retrieval and processing.

cs.CR
type: Class
title: Cryptography and Security
subclass of: ArxivCategory
subclass of: cs
definition: Covers all areas of cryptography and security including authentication, public key cryptosystems, proof-carrying code, etc.

cs.CV
type: Class
title: Computer Vision and Pattern Recognition
subclass of: ArxivCategory
subclass of: cs
definition: Covers image processing, computer vision, pattern recognition, and scene understanding.

cs.CY
type: Class
title: Computers and Society
subclass of: ArxivCategory
subclass of: cs
definition: Covers impact of computers on society, computer ethics, information technology and public policy, legal aspects of computing.

cs.DB
type: Class
title: Databases
subclass of: ArxivCategory
subclass of: cs
definition: Covers database management, datamining, and data processing. Roughly includes material in ACM Subject Classes H.2, H.3, and H.4.

cs.DC
type: Class
title: Distributed, Parallel, and Cluster Computing
subclass of: ArxivCategory
subclass of: cs
definition: Covers fault-tolerance, distributed algorithms, stabilization, parallel computation, and cluster computing.

cs.DL
type: Class
title: Digital Libraries
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of digital library design and document creation. Note this may overlap with other areas.

cs.DM
type: Class
title: Discrete Mathematics
subclass of: ArxivCategory
subclass of: cs
definition: Covers combinatorics, graph theory, applications of probability. Roughly includes material in ACM Subject Classes G.2 and G.3.

cs.DS
type: Class
title: Data Structures and Algorithms
subclass of: ArxivCategory
subclass of: cs
definition: Covers data structures and analysis of algorithms. Roughly includes material in ACM Subject Classes E.1, E.2, F.2.1, and F.2.2.

cs.ET
type: Class
title: Emerging Technologies
subclass of: ArxivCategory
subclass of: cs
definition: Covers approaches to computing based on emerging technologies such as quantum computing, DNA computing, optical computing.

cs.FL
type: Class
title: Formal Languages and Automata Theory
subclass of: ArxivCategory
subclass of: cs
definition: Covers automata theory, formal language theory, grammars, and combinatorics on words.

cs.GL
type: Class
title: General Literature
subclass of: ArxivCategory
subclass of: cs
definition: Covers introductory material, survey material, predictions of future trends, biographies, and miscellaneous computer-science related material.

cs.GR
type: Class
title: Graphics
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of computer graphics. Roughly includes material in ACM Subject Classes I.3.0-I.3.8.

cs.GT
type: Class
title: Computer Science and Game Theory
subclass of: ArxivCategory
subclass of: cs
definition: Covers all theoretical and applied aspects at the intersection of computer science and game theory.

cs.HC
type: Class
title: Human-Computer Interaction
subclass of: ArxivCategory
subclass of: cs
definition: Covers human factors, user interfaces, and collaborative computing. Roughly includes material in ACM Subject Classes H.1.2 and H.5.

cs.IR
type: Class
title: Information Retrieval
subclass of: ArxivCategory
subclass of: cs
definition: Covers indexing, dictionaries, retrieval, content and analysis. Roughly includes material in ACM Subject Classes H.3.0-H.3.4.

cs.IT
type: Class
title: Information Theory
subclass of: ArxivCategory
subclass of: cs
definition: Covers theoretical and experimental aspects of information theory and coding.

cs.LG
type: Class
title: Machine Learning
subclass of: ArxivCategory
subclass of: cs
definition: Papers on all aspects of machine learning research, including supervised, unsupervised, reinforcement learning, bandit algorithms.

cs.LO
type: Class
title: Logic in Computer Science
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of logic in computer science, including finite model theory, logics of programs, modal logic, and program verification.

cs.MA
type: Class
title: Multiagent Systems
subclass of: ArxivCategory
subclass of: cs
definition: Covers multiagent systems, distributed artificial intelligence, intelligent agents, coordinated interactions.

cs.MM
type: Class
title: Multimedia
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of multimedia systems, including hypermedia and information systems design.

cs.MS
type: Class
title: Mathematical Software
subclass of: ArxivCategory
subclass of: cs
definition: Covers aspects of mathematical software for mathematical computation and related support.

cs.NA
type: Class
title: Numerical Analysis
subclass of: ArxivCategory
subclass of: cs
definition: Covers numerical algorithms for problems in analysis and algebra. Includes numerical linear algebra, optimization, and interpolation.

cs.NE
type: Class
title: Neural and Evolutionary Computing
subclass of: ArxivCategory
subclass of: cs
definition: Covers neural networks, connectionism, genetic algorithms, artificial life, adaptive behavior.

cs.NI
type: Class
title: Networking and Internet Architecture
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of computer communication networks, including network architecture and design.

cs.OH
type: Class
title: Other Computer Science
subclass of: ArxivCategory
subclass of: cs
definition: Covers topics not fitting other computer science categories.

cs.OS
type: Class
title: Operating Systems
subclass of: ArxivCategory
subclass of: cs
definition: Covers aspects of operating systems including structure, design, management, and synchronization.

cs.PF
type: Class
title: Performance
subclass of: ArxivCategory
subclass of: cs
definition: Covers performance measurement, simulation, and evaluation methodology.

cs.PL
type: Class
title: Programming Languages
subclass of: ArxivCategory
subclass of: cs
definition: Covers programming language semantics, language features, programming approaches, compilers.

cs.RO
type: Class
title: Robotics
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of robotics, including control, manipulation, planning, and robot learning.

cs.SC
type: Class
title: Symbolic Computation
subclass of: ArxivCategory
subclass of: cs
definition: Covers symbolics, including computer algebra systems, implementation, and applications.

cs.SD
type: Class
title: Sound
subclass of: ArxivCategory
subclass of: cs
definition: Covers all aspects of computing with sound, and sound as an information channel.

cs.SE
type: Class
title: Software Engineering
subclass of: ArxivCategory
subclass of: cs
definition: Covers design tools, software metrics, testing and debugging, programming environments, requirements, specifications.

cs.SI
type: Class
title: Social and Information Networks
subclass of: ArxivCategory
subclass of: cs
definition: Covers design, analysis, and modeling of social and information networks, including their applications for online systems.

cs.SY
type: Class
title: Systems and Control
subclass of: ArxivCategory
subclass of: cs
definition: Covers theoretical and practical aspects of systems and control, including control system design.

econ.EM
type: Class
title: Econometrics
subclass of: ArxivCategory
subclass of: econ
definition: Econometric theory and practice, including estimation, hypothesis testing, and forecasting.

econ.GN
type: Class
title: General Economics
subclass of: ArxivCategory
subclass of: econ
definition: General methodological, applied, and empirical contributions to economics.

econ.TH
type: Class
title: Theoretical Economics
subclass of: ArxivCategory
subclass of: econ
definition: Includes decision theory, game theory, mechanism design, and mathematical modeling in economics.

eess.AS
type: Class
title: Audio and Speech Processing
subclass of: ArxivCategory
subclass of: eess
definition: Theory and methods for processing signals representing audio, speech, and language, and their applications.

eess.IV
type: Class
title: Image and Video Processing
subclass of: ArxivCategory
subclass of: eess
definition: Theory, algorithms, and applications for the formation, capture, processing, communication, analysis, and display of images.

eess.SP
type: Class
title: Signal Processing
subclass of: ArxivCategory
subclass of: eess
definition: Theory, algorithms, performance analysis and applications of signal and data analysis.

eess.SY
type: Class
title: Systems and Control
subclass of: ArxivCategory
subclass of: eess
definition: Analysis and design of control systems, covering mathematical modeling and automatic control.

gr-qc
type: Class
title: General Relativity and Quantum Cosmology
subclass of: ArxivCategory
subclass of: physics
definition: General relativity, gravitational physics, cosmological models, relativistic astrophysics.

hep-ex
type: Class
title: High Energy Physics - Experiment
subclass of: ArxivCategory
subclass of: hep
definition: Results from high-energy/particle physics experiments at accelerators and observatories.

hep-lat
type: Class
title: High Energy Physics - Lattice
subclass of: ArxivCategory
subclass of: hep
definition: Lattice field theory results with desired precision and algorithmic advances.

hep-ph
type: Class
title: High Energy Physics - Phenomenology
subclass of: ArxivCategory
subclass of: hep
definition: Theoretical particle physics and its relation to experiment. Covers Standard Model and beyond.

hep-th
type: Class
title: High Energy Physics - Theory
subclass of: ArxivCategory
subclass of: hep
definition: Formal aspects of quantum field theory, string theory, quantum gravity.

math-ph
type: Class
title: Mathematical Physics
subclass of: ArxivCategory
subclass of: physics
definition: Applications of mathematics to problems in physics and development of mathematical methods for such applications.

math.AC
type: Class
title: Commutative Algebra
subclass of: ArxivCategory
subclass of: math
definition: Commutative rings, modules, ideals, homological algebra, computational aspects, local rings.

math.AG
type: Class
title: Algebraic Geometry
subclass of: ArxivCategory
subclass of: math
definition: Algebraic varieties, stacks, sheaves, schemes, moduli spaces, complex geometry, quantum cohomology.

math.AP
type: Class
title: Analysis of PDEs
subclass of: ArxivCategory
subclass of: math
definition: Existence and uniqueness, boundary conditions, linear and non-linear operators, stability, soliton theory.

math.AT
type: Class
title: Algebraic Topology
subclass of: ArxivCategory
subclass of: math
definition: Homotopy theory, homological algebra, algebraic treatments of manifolds.

math.CA
type: Class
title: Classical Analysis and ODEs
subclass of: ArxivCategory
subclass of: math
definition: Special functions, orthogonal polynomials, harmonic analysis, ODEs, differential relations.

math.CO
type: Class
title: Combinatorics
subclass of: ArxivCategory
subclass of: math
definition: Discrete mathematics, graph theory, enumeration, combinatorial optimization.

math.CT
type: Class
title: Category Theory
subclass of: ArxivCategory
subclass of: math
definition: Enriched categories, topoi, abelian categories, monoidal categories, homological algebra.

math.CV
type: Class
title: Complex Variables
subclass of: ArxivCategory
subclass of: math
definition: Holomorphic functions, automorphic group actions, and their generalizations, complex geometry.

math.DG
type: Class
title: Differential Geometry
subclass of: ArxivCategory
subclass of: math
definition: Complex, contact, Riemannian, pseudo-Riemannian, symplectic geometry, relativity, gauge theory.

math.DS
type: Class
title: Dynamical Systems
subclass of: ArxivCategory
subclass of: math
definition: Dynamics of differential equations and flows, mechanics, classical few-body problems.

math.FA
type: Class
title: Functional Analysis
subclass of: ArxivCategory
subclass of: math
definition: Banach spaces, function spaces, real functions, distributions, measures, integration.

math.GM
type: Class
title: General Mathematics
subclass of: ArxivCategory
subclass of: math
definition: Mathematical material of general interest, broadly accessible expositions of research results.

math.GN
type: Class
title: General Topology
subclass of: ArxivCategory
subclass of: math
definition: Continuum theory, point-set topology, spaces with algebraic structure, topological dynamics.

math.GR
type: Class
title: Group Theory
subclass of: ArxivCategory
subclass of: math
definition: Finite groups, topological groups, representation theory, cohomology, classification.

math.GT
type: Class
title: Geometric Topology
subclass of: ArxivCategory
subclass of: math
definition: Manifolds, orbifolds, polyhedra, cell complexes, foliations, geometric structures.

math.HO
type: Class
title: History and Overview
subclass of: ArxivCategory
subclass of: math
definition: Biographies, philosophy of mathematics, mathematics education, recreational mathematics.

math.IT
type: Class
title: Information Theory
subclass of: ArxivCategory
subclass of: math
definition: Math methods in information theory and coding theory.

math.KT
type: Class
title: K-Theory and Homology
subclass of: ArxivCategory
subclass of: math
definition: Algebraic and topological K-theory, relations with topology, commutative algebra, index theories.

math.LO
type: Class
title: Logic
subclass of: ArxivCategory
subclass of: math
definition: Logic, set theory, point-set topology, formal mathematics.

math.MG
type: Class
title: Metric Geometry
subclass of: ArxivCategory
subclass of: math
definition: Euclidean, hyperbolic, discrete, convex, coarse geometry, comparisons in Riemannian geometry.

math.MP
type: Class
title: Mathematical Physics
subclass of: ArxivCategory
subclass of: math
definition: Articles in which math methods are used to study physics problems, or math questions arising from physics.

math.NA
type: Class
title: Numerical Analysis
subclass of: ArxivCategory
subclass of: math
definition: Numerical algorithms for problems in analysis and algebra, scientific computation.

math.NT
type: Class
title: Number Theory
subclass of: ArxivCategory
subclass of: math
definition: Prime numbers, diophantine equations, analytic number theory, algebraic number theory, arithmetic geometry.

math.OA
type: Class
title: Operator Algebras
subclass of: ArxivCategory
subclass of: math
definition: Algebras of operators on Hilbert space, C*-algebras, von Neumann algebras, non-commutative geometry.

math.OC
type: Class
title: Optimization and Control
subclass of: ArxivCategory
subclass of: math
definition: Operations research, linear programming, control theory, systems theory, optimal control.

math.PR
type: Class
title: Probability
subclass of: ArxivCategory
subclass of: math
definition: Theory and applications of probability and stochastic processes, including stochastic differential equations.

math.QA
type: Class
title: Quantum Algebra
subclass of: ArxivCategory
subclass of: math
definition: Quantum groups, skein theories, operadic and diagrammatic algebra, quantum field theory.

math.RA
type: Class
title: Rings and Algebras
subclass of: ArxivCategory
subclass of: math
definition: Non-commutative rings and algebras, non-associative algebras, universal algebra.

math.RT
type: Class
title: Representation Theory
subclass of: ArxivCategory
subclass of: math
definition: Linear representations of algebras and groups, Lie theory, associative algebras.

math.SG
type: Class
title: Symplectic Geometry
subclass of: ArxivCategory
subclass of: math
definition: Hamiltonian systems, symplectic flows, classical integrable systems.

math.SP
type: Class
title: Spectral Theory
subclass of: ArxivCategory
subclass of: math
definition: Schrodinger operators, differential operators, spectral measures, scattering theory.

math.ST
type: Class
title: Statistics Theory
subclass of: ArxivCategory
subclass of: math
definition: Applied, computational and theoretical statistics including probability, coverage, learning theory.

nlin.AO
type: Class
title: Adaptation and Self-Organizing Systems
subclass of: ArxivCategory
subclass of: nlin
definition: Self-organization, adaptation, and autonomous systems.

nlin.CD
type: Class
title: Chaotic Dynamics
subclass of: ArxivCategory
subclass of: nlin
definition: Dynamical systems with chaotic behavior, routes to chaos, spectral analysis, Lyapunov exponents.

nlin.CG
type: Class
title: Cellular Automata and Lattice Gases
subclass of: ArxivCategory
subclass of: nlin
definition: Cellular automata, lattice Boltzmann, lattice gas automata, signal processing with cellular automata.

nlin.PS
type: Class
title: Pattern Formation and Solitons
subclass of: ArxivCategory
subclass of: nlin
definition: Pattern formation, coherent structures, solitons, waves.

nlin.SI
type: Class
title: Exactly Solvable and Integrable Systems
subclass of: ArxivCategory
subclass of: nlin
definition: Integrable PDEs, integrable ODEs, Painleve analysis, integrable discrete systems.

nucl-ex
type: Class
title: Nuclear Experiment
subclass of: ArxivCategory
subclass of: nucl
definition: Experimental results from nuclear physics laboratories, such as heavy-ion collisions.

nucl-th
type: Class
title: Nuclear Theory
subclass of: ArxivCategory
subclass of: nucl
definition: Theory of nuclear structure and low-energy reactions, including heavy-ion physics.

physics.acc-ph
type: Class
title: Accelerator Physics
subclass of: ArxivCategory
subclass of: physics
definition: Accelerator theory and target design, beam physics, secondary beams, photon sources.

physics.ao-ph
type: Class
title: Atmospheric and Oceanic Physics
subclass of: ArxivCategory
subclass of: physics
definition: Atmospheric and oceanic processes, climate dynamics, waves, boundary layer physics.

physics.app-ph
type: Class
title: Applied Physics
subclass of: ArxivCategory
subclass of: physics
definition: Applications of physics to new technology, medical physics, instrumentation.

physics.atm-clus
type: Class
title: Atomic and Molecular Clusters
subclass of: ArxivCategory
subclass of: physics
definition: Binding, structure, and properties of clusters, nanoparticles.

physics.atom-ph
type: Class
title: Atomic Physics
subclass of: ArxivCategory
subclass of: physics
definition: Atomic and molecular structure, spectra, collisions, and data. Ultrafast physics, molecular physics.

physics.bio-ph
type: Class
title: Biological Physics
subclass of: ArxivCategory
subclass of: physics
definition: Molecular biophysics, cellular biophysics, single molecule biophysics.

physics.chem-ph
type: Class
title: Chemical Physics
subclass of: ArxivCategory
subclass of: physics
definition: Experimental, methods, and results in chemical physics and molecular dynamics.

physics.class-ph
type: Class
title: Classical Physics
subclass of: ArxivCategory
subclass of: physics
definition: Newtonian and Lagrangian mechanics, electromagnetism, thermodynamics, special relativity.

physics.comp-ph
type: Class
title: Computational Physics
subclass of: ArxivCategory
subclass of: physics
definition: All aspects of computational science applied to physics problems.

physics.data-an
type: Class
title: Data Analysis, Statistics and Probability
subclass of: ArxivCategory
subclass of: physics
definition: Methods, software, and results in physics data analysis.

physics.ed-ph
type: Class
title: Physics Education
subclass of: ArxivCategory
subclass of: physics
definition: Physics teaching and learning research.

physics.flu-dyn
type: Class
title: Fluid Dynamics
subclass of: ArxivCategory
subclass of: physics
definition: Turbulence, instabilities, incompressible and compressible flows, boundary layers.

physics.gen-ph
type: Class
title: General Physics
subclass of: ArxivCategory
subclass of: physics
definition: General physics that does not fit elsewhere.

physics.geo-ph
type: Class
title: Geophysics
subclass of: ArxivCategory
subclass of: physics
definition: Computational and theoretical geophysics including seismology, potential theory.

physics.hist-ph
type: Class
title: History and Philosophy of Physics
subclass of: ArxivCategory
subclass of: physics
definition: History and philosophy of all aspects of physics.

physics.ins-det
type: Class
title: Instrumentation and Detectors
subclass of: ArxivCategory
subclass of: physics
definition: Instrumentation and detectors for accelerator, astro-, geo-, or particle physics.

physics.med-ph
type: Class
title: Medical Physics
subclass of: ArxivCategory
subclass of: physics
definition: Radiation therapy, biomedical imaging, health physics.

physics.optics
type: Class
title: Optics
subclass of: ArxivCategory
subclass of: physics
definition: Adaptive optics, polarimetry, quantum optics, ultrafast optics, photonics.

physics.plasm-ph
type: Class
title: Plasma Physics
subclass of: ArxivCategory
subclass of: physics
definition: Fundamental plasma physics, magnetic and inertial confinement, astrophysical plasmas.

physics.pop-ph
type: Class
title: Popular Physics
subclass of: ArxivCategory
subclass of: physics
definition: General physics topics for a broad audience.

physics.soc-ph
type: Class
title: Physics and Society
subclass of: ArxivCategory
subclass of: physics
definition: Sociophysics, structure and dynamics of societies, opinion dynamics.

physics.space-ph
type: Class
title: Space Physics
subclass of: ArxivCategory
subclass of: physics
definition: Space plasma physics, magnetospheric physics, solar wind, cosmic rays.

q-bio.BM
type: Class
title: Biomolecules
subclass of: ArxivCategory
subclass of: q-bio
definition: DNA, RNA, proteins, lipids, small molecules; molecular structure and dynamics; molecular engineering.

q-bio.CB
type: Class
title: Cell Behavior
subclass of: ArxivCategory
subclass of: q-bio
definition: Cell-cell signaling, morphogenesis, development; cell division/cycle; immunology.

q-bio.GN
type: Class
title: Genomics
subclass of: ArxivCategory
subclass of: q-bio
definition: DNA sequencing and assembly; gene finding; genome structure, organization, and regulation.

q-bio.MN
type: Class
title: Molecular Networks
subclass of: ArxivCategory
subclass of: q-bio
definition: Gene regulation, signal transduction, metabolic networks, kinetics, synthetic biology.

q-bio.NC
type: Class
title: Neurons and Cognition
subclass of: ArxivCategory
subclass of: q-bio
definition: Synapse, receptor dynamics, learning, neural coding, neuroinformatics.

q-bio.OT
type: Class
title: Other Quantitative Biology
subclass of: ArxivCategory
subclass of: q-bio
definition: Work in quantitative biology that does not fit in the other q-bio classifications.

q-bio.PE
type: Class
title: Populations and Evolution
subclass of: ArxivCategory
subclass of: q-bio
definition: Population dynamics, spatio-temporal evolution, migration, phylogeny, biodiversity.

q-bio.QM
type: Class
title: Quantitative Methods
subclass of: ArxivCategory
subclass of: q-bio
definition: Research papers with experimental, numerical, or statistical contributions of value to biologists.

q-bio.SC
type: Class
title: Subcellular Processes
subclass of: ArxivCategory
subclass of: q-bio
definition: Subcellular structures, molecular motors, organelle transport, packaging.

q-bio.TO
type: Class
title: Tissues and Organs
subclass of: ArxivCategory
subclass of: q-bio
definition: Blood flow, biomechanics, tumor growth, tissue morphogenesis.

q-fin.CP
type: Class
title: Computational Finance
subclass of: ArxivCategory
subclass of: q-fin
definition: Monte Carlo, PDE, and other numerical methods with applications to quantitative finance.

q-fin.EC
type: Class
title: Economics
subclass of: ArxivCategory
subclass of: q-fin
definition: General economics topics with quantitative approaches.

q-fin.GN
type: Class
title: General Finance
subclass of: ArxivCategory
subclass of: q-fin
definition: General quantitative financial methodologies covering multiple sub-fields.

q-fin.MF
type: Class
title: Mathematical Finance
subclass of: ArxivCategory
subclass of: q-fin
definition: Mathematical and analytical methods in finance, stochastic methods, hedging strategies.

q-fin.PM
type: Class
title: Portfolio Management
subclass of: ArxivCategory
subclass of: q-fin
definition: Security selection and optimization, capital allocation, investment strategies.

q-fin.PR
type: Class
title: Pricing of Securities
subclass of: ArxivCategory
subclass of: q-fin
definition: Valuation and hedging of financial securities, their derivatives, and structured products.

q-fin.RM
type: Class
title: Risk Management
subclass of: ArxivCategory
subclass of: q-fin
definition: Measurement and management of financial risks in trading, banking, insurance.

q-fin.ST
type: Class
title: Statistical Finance
subclass of: ArxivCategory
subclass of: q-fin
definition: Statistical, econometric methods applied to financial markets.

q-fin.TR
type: Class
title: Trading and Market Microstructure
subclass of: ArxivCategory
subclass of: q-fin
definition: Market microstructure, algorithmic trading, order book dynamics.

quant-ph
type: Class
title: Quantum Physics
subclass of: ArxivCategory
subclass of: physics
definition: Quantum foundations, quantum information, quantum computation, quantum mechanics.

stat.AP
type: Class
title: Applications
subclass of: ArxivCategory
subclass of: stat
definition: Biology, education, epidemiology, engineering, environmental sciences, medical, physical sciences.

stat.CO
type: Class
title: Computation
subclass of: ArxivCategory
subclass of: stat
definition: Algorithms, computational methods, simulation, visualization.

stat.ME
type: Class
title: Methodology
subclass of: ArxivCategory
subclass of: stat
definition: Design, surveys, model selection, regression, testing, time series.

stat.ML
type: Class
title: Machine Learning
subclass of: ArxivCategory
subclass of: stat
definition: Covers machine learning papers with a statistical or theoretical grounding.

stat.OT
type: Class
title: Other Statistics
subclass of: ArxivCategory
subclass of: stat
definition: Work in statistics that does not fit into the other stat-* classifications.

stat.TH
type: Class
title: Statistics Theory
subclass of: ArxivCategory
subclass of: stat
definition: Asymptotics, Bayesian inference, decision theory, estimation, foundations, inference.

AAC
type: Class
subclass of: AudioFormatEnum
definition: Advanced Audio Coding
compression: lossy
extension: .aac
mime type: audio/aac

AIFF
type: Class
subclass of: AudioFormatEnum
definition: Audio Interchange File Format
creator: Apple
extension: .aiff, .aif
mime type: audio/aiff

FLAC
type: Class
subclass of: AudioFormatEnum
definition: Free Lossless Audio Codec
compression: lossless
extension: .flac
mime type: audio/flac

M4A
type: Class
subclass of: AudioFormatEnum
definition: MPEG-4 Audio
compression: lossy or lossless
extension: .m4a
mime type: audio/mp4

MP3
type: Class
subclass of: AudioFormatEnum
definition: MPEG Audio Layer 3
compression: lossy
extension: .mp3
mime type: audio/mpeg

OGG
type: Class
subclass of: AudioFormatEnum
definition: Ogg Vorbis
compression: lossy
extension: .ogg
mime type: audio/ogg

OPUS
type: Class
subclass of: AudioFormatEnum
definition: Opus Interactive Audio Codec
extension: .opus
mime type: audio/opus
use: streaming, VoIP

WAV
type: Class
subclass of: AudioFormatEnum
definition: Waveform Audio File Format
compression: uncompressed
extension: .wav
mime type: audio/wav

WMA
type: Class
subclass of: AudioFormatEnum
definition: Windows Media Audio
creator: Microsoft
extension: .wma
mime type: audio/x-ms-wma

AUTOPROTOCOL
type: Class
title: Autoprotocol
subclass of: AutomationStandardEnum
definition: JSON-based language for specifying experimental protocols
format: JSON

CLSI_AUTO01
type: Class
title: CLSI AUTO01
subclass of: AutomationStandardEnum
definition: CLSI standard for Specimen Container/Specimen Carrier
organization: Clinical and Laboratory Standards Institute

CLSI_AUTO02
type: Class
title: CLSI AUTO02
subclass of: AutomationStandardEnum
definition: CLSI standard for Bar Codes for Specimen Container Identification
organization: Clinical and Laboratory Standards Institute

CLSI_AUTO03
type: Class
title: CLSI AUTO03
subclass of: AutomationStandardEnum
definition: CLSI standard for Communications with Automated Clinical Laboratory Systems
organization: Clinical and Laboratory Standards Institute

CLSI_AUTO04
type: Class
title: CLSI AUTO04
subclass of: AutomationStandardEnum
definition: CLSI standard for Systems Operational Requirements, Characteristics, and Information Elements
organization: Clinical and Laboratory Standards Institute

CLSI_AUTO05
type: Class
title: CLSI AUTO05
subclass of: AutomationStandardEnum
definition: CLSI standard for Electromechanical Interfaces
organization: Clinical and Laboratory Standards Institute

LABOP
type: Class
title: LabOP
subclass of: AutomationStandardEnum
definition: Laboratory Open Protocol Language - open specification for laboratory protocols
format: RDF/OWL
organization: Bioprotocols Working Group

SILA_2
type: Class
title: SiLA 2
subclass of: AutomationStandardEnum
definition: Standardization in Lab Automation version 2 - international standard for open connectivity in lab automation
architecture: microservice-based
organization: Society for Laboratory Automation and Screening
protocol: gRPC

AI_EXPERIMENT_PLANNER
type: Class
subclass of: AutonomousLabComponentType
definition: AI-based software system that designs and plans experiments based on prior data and objectives
function: experiment planning and design

AUTOMATED_CHARACTERIZATION_INSTRUMENT
type: Class
subclass of: AutonomousLabComponentType
definition: Instrument for automated measurement and characterization of samples
examples: automated XRD, SEM, spectroscopy

AUTOMATED_SYNTHESIZER
type: Class
subclass of: AutonomousLabComponentType
broad match: NCIT C50206
definition: Automated system for chemical or biological synthesis operations
function: automated synthesis

DATA_MANAGEMENT_SYSTEM
type: Class
subclass of: AutonomousLabComponentType
definition: System for automated collection, storage, and management of experimental data
function: data management and integration

ROBOTIC_SAMPLE_HANDLER
type: Class
subclass of: AutonomousLabComponentType
definition: Robotic system for automated sample manipulation, transfer, and preparation
function: sample handling and transfer

SAFETY_MONITORING_SYSTEM
type: Class
subclass of: AutonomousLabComponentType
definition: System for real-time monitoring of laboratory safety conditions and automated hazard response
function: safety monitoring and emergency response

SAMPLE_STORAGE_SYSTEM
type: Class
subclass of: AutonomousLabComponentType
definition: Automated storage and retrieval system for laboratory samples
function: sample storage and inventory management

ASSISTIVE
type: Class
subclass of: AutonomyLevel
definition: Human operator with assistive technologies

FULLY_AUTONOMOUS
type: Class
subclass of: AutonomyLevel
definition: Complete autonomous operation without human intervention

SEMI_AUTONOMOUS
type: Class
subclass of: AutonomyLevel
definition: Partial autonomy with human intervention capability

SUPERVISED_AUTONOMY
type: Class
subclass of: AutonomyLevel
definition: Autonomous operation with human supervision

NORMAL_WEIGHT
type: Class
title: BMI 18.5-24.9
subclass of: BMIClassificationEnum
bmi range: 18.5-24.9

OBESE_CLASS_I
type: Class
title: BMI 30.0-34.9
subclass of: BMIClassificationEnum
bmi range: 30.0-34.9

OBESE_CLASS_II
type: Class
title: BMI 35.0-39.9
subclass of: BMIClassificationEnum
bmi range: 35.0-39.9

OBESE_CLASS_III
type: Class
title: BMI 40.0 or greater
subclass of: BMIClassificationEnum
aliases: morbid obesity
bmi range: ≥40.0

OVERWEIGHT
type: Class
title: BMI 25.0-29.9
subclass of: BMIClassificationEnum
bmi range: 25.0-29.9

UNDERWEIGHT
type: Class
title: BMI less than 18.5
subclass of: BMIClassificationEnum
bmi range: <18.5

IRON_AIR
type: Class
subclass of: BatteryType
definition: Iron-air battery
chemistry: iron

LEAD_ACID
type: Class
subclass of: BatteryType
alternative label: Pb-acid
definition: Lead-acid battery
chemistry: lead

LITHIUM_ION
type: Class
subclass of: BatteryType
alternative label: LIB
alternative label: Li-ion
definition: Lithium-ion battery
chemistry: lithium

LITHIUM_IRON_PHOSPHATE
type: Class
subclass of: BatteryType
alternative label: LFP
alternative label: LiFePO4
definition: Lithium iron phosphate (LFP) battery
chemistry: lithium

LITHIUM_POLYMER
type: Class
subclass of: BatteryType
alternative label: LiPo
definition: Lithium polymer battery
chemistry: lithium

NICKEL_CADMIUM
type: Class
subclass of: BatteryType
alternative label: NiCd
definition: Nickel-cadmium battery
chemistry: nickel

NICKEL_METAL_HYDRIDE
type: Class
subclass of: BatteryType
alternative label: NiMH
definition: Nickel-metal hydride battery
chemistry: nickel

SODIUM_ION
type: Class
subclass of: BatteryType
alternative label: Na-ion
definition: Sodium-ion battery
chemistry: sodium

SOLID_STATE
type: Class
subclass of: BatteryType
definition: Solid-state battery
chemistry: various

VANADIUM_REDOX_FLOW
type: Class
subclass of: BatteryType
alternative label: VRB
alternative label: VRFB
definition: Vanadium redox flow battery
chemistry: vanadium
type: flow

ZINC_AIR
type: Class
subclass of: BatteryType
definition: Zinc-air battery
chemistry: zinc

ZINC_BROMINE_FLOW
type: Class
subclass of: BatteryType
alternative label: ZnBr
definition: Zinc-bromine flow battery
chemistry: zinc
type: flow

BIO_BENEFICIATION
type: Class
subclass of: BeneficiationPathway
definition: Biological methods for mineral beneficiation

DENSE_MEDIUM_SEPARATION
type: Class
subclass of: BeneficiationPathway
definition: Gravity separation using dense media

ELECTRIC_PULSE_PREWEAKENING
type: Class
subclass of: BeneficiationPathway
definition: High-voltage electric pulse fragmentation

ELECTROSTATIC_SEP
type: Class
subclass of: BeneficiationPathway
definition: Electrostatic separation of minerals

FLOTATION_LOW_H2O
type: Class
subclass of: BeneficiationPathway
definition: Low-water flotation processes

GRINDING_DYNAMIC
type: Class
subclass of: BeneficiationPathway
definition: Dynamic grinding optimization systems

MAGNETIC_SEP
type: Class
subclass of: BeneficiationPathway
definition: Magnetic separation of ferromagnetic minerals

MICROWAVE_PREWEAKENING
type: Class
subclass of: BeneficiationPathway
definition: Microwave treatment to weaken ore structure

ORE_SORTING
type: Class
subclass of: BeneficiationPathway
definition: Sensor-based sorting of ore particles

FLEXIBLE_BENEFITS
type: Class
title: Flexible Benefits
subclass of: BenefitsCategoryEnum
definition: Flexible spending and benefit choice options
choice: benefit choice
customization: personalized benefits
lifestyle: lifestyle accommodation
spending: flexible spending accounts
tax advantage: tax advantages

HEALTH_INSURANCE
type: Class
title: Health Insurance
subclass of: BenefitsCategoryEnum
definition: Medical, dental, and vision insurance coverage
cost sharing: employer contribution
coverage: medical coverage
essential: essential benefit
family: family coverage options
networks: provider networks

LIFE_INSURANCE
type: Class
title: Life Insurance
subclass of: BenefitsCategoryEnum
definition: Life and disability insurance coverage
beneficiaries: beneficiary designation
disability: disability coverage
group: group coverage
peace of mind: financial security
protection: financial protection

PAID_TIME_OFF
type: Class
title: Paid Time Off
subclass of: BenefitsCategoryEnum
definition: Vacation, sick leave, and personal time
accrual: accrual systems
personal: personal days
sick: sick leave
vacation: vacation time
work life: work-life balance

PROFESSIONAL_DEVELOPMENT
type: Class
title: Professional Development
subclass of: BenefitsCategoryEnum
definition: Training, education, and career development benefits
career: career development
education: continuing education
growth: professional growth
skill: skill enhancement
training: professional training

RETIREMENT_BENEFITS
type: Class
title: Retirement Benefits
subclass of: BenefitsCategoryEnum
definition: Retirement savings and pension plans
long term: long-term benefit
matching: employer matching
planning: retirement planning
savings: 401(k) or retirement savings
vesting: vesting schedules

WELLNESS_PROGRAMS
type: Class
title: Wellness Programs
subclass of: BenefitsCategoryEnum
definition: Employee health and wellness initiatives
culture: wellness culture
fitness: fitness programs
health: health promotion
mental health: mental health support
prevention: preventive care

WORK_LIFE_BALANCE
type: Class
title: Work-Life Balance Benefits
subclass of: BenefitsCategoryEnum
definition: Benefits supporting work-life integration
balance: life balance
childcare: childcare assistance
elder care: elder care support
family: family support
flexibility: work flexibility

NRP
type: Class
title: Non-ribosomal peptide
subclass of: BgcCategoryEnum
definition: Non-ribosomal peptide biosynthetic gene clusters
biosynthetic enzyme: Non-ribosomal peptide synthetase (NRPS)
definition: Peptides synthesized by non-ribosomal peptide synthetases
examples: Penicillin, vancomycin, cyclosporin

OTHER
type: Class
subclass of: BgcCategoryEnum
definition: Other or unclassified biosynthetic gene clusters
definition: BGCs that do not fit into standard categories or are of unknown type
examples: Novel or hybrid BGCs

RIPP
type: Class
title: Ribosomally synthesized and post-translationally modified peptide
subclass of: BgcCategoryEnum
definition: RiPP biosynthetic gene clusters
biosynthetic enzyme: Various modifying enzymes
definition: Ribosomally synthesized peptides with extensive post-translational modifications
examples: Nisin, thiopeptides, lanthipeptides
related chebi: CHEBI:71629 (nisin)

BinaryClassificationEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Binary Classification
status: DRAFT
subclass of: BinaryClassificationSchemaEnum
union of: NCIT C38758
union of: NCIT C35681
definition: Generic binary classification labels
in scheme: merged
permissible values: NCIT C35681
permissible values: NCIT C38758
source domain: data_science
source schema: binary_classification

ACID_HYDROLYSIS
type: Class
title: Acid Hydrolysis
subclass of: BioconversionProcess
definition: Chemical breakdown of cellulose to sugars using dilute or concentrated acid.
category: chemical
pretreatment step: true

ALCOHOL_TO_JET
type: Class
title: Alcohol-to-Jet (ATJ)
subclass of: BioconversionProcess
alternative label: ATJ
definition: Conversion of alcohols (ethanol, isobutanol) to jet fuel through dehydration, oligomerization, and hydrogenation.
category: chemical
products: SAF

ANAEROBIC_DIGESTION
type: Class
title: Anaerobic Digestion
subclass of: BioconversionProcess
definition: Biological breakdown of organic matter by microorganisms in the absence of oxygen, producing biogas.
category: biochemical
products: biogas

ENZYMATIC_HYDROLYSIS
type: Class
title: Enzymatic Hydrolysis
subclass of: BioconversionProcess
definition: Breakdown of cellulose and hemicellulose to fermentable sugars using enzymes.
category: biochemical
pretreatment step: true

FERMENTATION
type: Class
title: Fermentation
subclass of: BioconversionProcess
definition: Biological conversion of sugars to alcohols using yeast or bacteria.
category: biochemical
products: ethanol,butanol

FISCHER_TROPSCH
type: Class
title: Fischer-Tropsch Synthesis
subclass of: BioconversionProcess
alternative label: FT Synthesis
definition: Catalytic conversion of syngas to liquid hydrocarbons.
category: thermochemical
feedstock: syngas
products: FT_diesel,FT_jet

HYDROTHERMAL_LIQUEFACTION
type: Class
title: Hydrothermal Liquefaction (HTL)
subclass of: BioconversionProcess
alternative label: HTL
definition: Conversion of wet biomass to bio-crude using high temperature and pressure water.
category: thermochemical
pressure bar: 100-200
temperature c: 250-400
wet feedstock: true

HYDROTREATING
type: Class
title: Hydrotreating/Hydroprocessing
subclass of: BioconversionProcess
alternative label: Hydroprocessing
definition: Catalytic reaction of lipids with hydrogen to produce hydrocarbon fuels.
category: thermochemical
products: renewable_diesel,SAF

PYROLYSIS
type: Class
title: Pyrolysis
subclass of: BioconversionProcess
definition: Thermal decomposition of biomass in the absence of oxygen to produce bio-oil, syngas, and biochar.
category: thermochemical
products: bio_oil,syngas,biochar
temperature c: 400-600

TRANSESTERIFICATION
type: Class
title: Transesterification
subclass of: BioconversionProcess
definition: Chemical reaction of triglycerides with alcohol to produce fatty acid esters (biodiesel) and glycerol.
category: chemical
products: biodiesel

BIOACCUMULATION
type: Class
subclass of: BioextractionMethodType
definition: Active uptake and intracellular concentration of metals by living organisms
mechanism: metabolically driven intracellular uptake
organisms: bacteria, fungi, algae

BIOFLOTATION
type: Class
subclass of: BioextractionMethodType
definition: Use of microorganisms or biosurfactants to selectively separate mineral particles by flotation
mechanism: selective surface modification
organisms: Mycobacterium, Bacillus

BIOPRECIPITATION
type: Class
subclass of: BioextractionMethodType
broad match: CHMO_0001688
definition: Microbially mediated precipitation of metals as insoluble compounds such as sulfides or phosphates
mechanism: sulfate reduction, phosphate release
products: metal sulfides, metal phosphates

BIOSORPTION
type: Class
subclass of: BioextractionMethodType
definition: Passive binding of metal ions to the surface of biological materials such as microbial biomass
materials: dead biomass, algae, fungi
mechanism: surface complexation, ion exchange

HEAP_BIOLEACHING
type: Class
subclass of: BioextractionMethodType
broad match: CHMO_0001681
definition: Biological leaching of metals from crushed ore stacked in heaps irrigated with acidic microbial solutions
organisms: Acidithiobacillus ferrooxidans, Acidithiobacillus thiooxidans
scale: industrial

IN_SITU_BIOLEACHING
type: Class
subclass of: BioextractionMethodType
broad match: CHMO_0001681
definition: Biological leaching of metals directly in the ore body without excavation
advantage: minimal surface disturbance
application: low-grade deposits

PHYTOMINING
type: Class
subclass of: BioextractionMethodType
definition: Use of hyperaccumulator plants to extract metals from soil or mining waste for recovery
metals: nickel, zinc, thallium
organisms: Alyssum, Thlaspi, Pteris

STIRRED_TANK_BIOLEACHING
type: Class
subclass of: BioextractionMethodType
broad match: CHMO_0001681
definition: Biological leaching of metals in agitated tank reactors with controlled conditions
organisms: Acidithiobacillus, Leptospirillum
scale: industrial, pilot

FIRST_GENERATION
type: Class
title: First Generation Biofuel
subclass of: BiofuelGeneration
alternative label: 1G Biofuel
alternative label: Conventional Biofuel
definition: Biofuels produced from food crops (sugar, starch, vegetable oils) using conventional conversion technologies.
examples: corn_ethanol,soy_biodiesel
feedstock: food_crops

FOURTH_GENERATION
type: Class
title: Fourth Generation Biofuel
subclass of: BiofuelGeneration
alternative label: 4G Biofuel
definition: Biofuels from genetically engineered organisms designed for carbon capture and enhanced fuel production.
carbon negative: true
feedstock: engineered_organisms

SECOND_GENERATION
type: Class
title: Second Generation Biofuel
subclass of: BiofuelGeneration
alternative label: 2G Biofuel
alternative label: Advanced Biofuel
alternative label: Cellulosic Biofuel
definition: Biofuels produced from lignocellulosic biomass (non-food) using advanced conversion technologies.
examples: cellulosic_ethanol,wood_diesel
feedstock: lignocellulosic

THIRD_GENERATION
type: Class
title: Third Generation Biofuel
subclass of: BiofuelGeneration
alternative label: 3G Biofuel
alternative label: Algal Biofuel
definition: Biofuels produced from algae or other photosynthetic microorganisms.
feedstock: algae

BIODIESEL
type: Class
title: Biodiesel
subclass of: BiofuelType
alternative label: FAME
definition: Fatty acid methyl esters (FAME) produced by transesterification of vegetable oils or animal fats.
production method: transesterification

BIOGAS
type: Class
title: Biogas
subclass of: BiofuelType
alternative label: Raw Biogas
definition: Gaseous mixture of methane and CO2 produced by anaerobic digestion of organic matter.
methane content percent: 50-70

BIOMETHANE
type: Class
title: Biomethane
subclass of: BiofuelType
alternative label: RNG
alternative label: Renewable Natural Gas
broad match: Methane
definition: Purified biogas upgraded to natural gas quality (>95% methane).
methane content percent: 95+
pipeline quality: true

BIO_OIL
type: Class
title: Bio-Oil
subclass of: BiofuelType
alternative label: Pyrolysis Oil
definition: Liquid intermediate produced by pyrolysis or hydrothermal liquefaction of biomass.
intermediate: true

RENEWABLE_DIESEL
type: Class
title: Renewable Diesel
subclass of: BiofuelType
alternative label: Green Diesel
alternative label: HVO
alternative label: Hydrotreated Vegetable Oil
definition: Hydrocarbon diesel produced by hydrotreating lipids. Chemically identical to petroleum diesel.
drop in fuel: true

SUSTAINABLE_AVIATION_FUEL
type: Class
title: Sustainable Aviation Fuel (SAF)
subclass of: BiofuelType
alternative label: Biojet
alternative label: SAF
definition: Jet fuel produced from biomass or waste, meeting aviation fuel specifications.
drop in fuel: true

SYNGAS
type: Class
title: Syngas (Bio-Based)
subclass of: BiofuelType
alternative label: Synthesis Gas
alternative label: gasification
definition: Synthesis gas (CO + H2) produced by gasification of biomass.
intermediate: true

INDIRECT_BIOLEACH_ORGANIC_ACIDS
type: Class
subclass of: BioleachMode
definition: Indirect bioleaching through organic acid production

IRON_OXIDATION
type: Class
subclass of: BioleachMode
definition: Direct bacterial oxidation of iron compounds

SULFUR_OXIDATION
type: Class
subclass of: BioleachMode
definition: Direct bacterial oxidation of sulfur compounds

ENGINEERED_STRAIN
type: Class
subclass of: BioleachOrganism
definition: Genetically modified organism for enhanced bioleaching

PROTISTA
type: Class
subclass of: BiologicalKingdom
definition: Protist kingdom (polyphyletic group)

BENCH_SCALE
type: Class
subclass of: BiomanufacturingScaleType
definition: Laboratory bench scale operations, typically less than 10 liters
purpose: Initial development and screening
volume range: <10 L

COMMERCIAL_SCALE
type: Class
subclass of: BiomanufacturingScaleType
definition: Full commercial production scale, typically greater than 10000 liters
purpose: Commercial manufacturing
volume range: >10000 L

DEMONSTRATION_SCALE
type: Class
subclass of: BiomanufacturingScaleType
definition: Demonstration scale operations for technology validation, typically 1000-10000 liters
purpose: Technology demonstration and validation
volume range: 1000-10000 L

MICRO_SCALE
type: Class
subclass of: BiomanufacturingScaleType
definition: Micro-scale operations using microfluidic or microtiter plate formats, typically less than 1 mL
purpose: High-throughput screening and optimization
volume range: <1 mL

PILOT_SCALE
type: Class
subclass of: BiomanufacturingScaleType
definition: Pilot plant scale operations for process development, typically 10-1000 liters
purpose: Process development and optimization
volume range: 10-1000 L

ALGAE
type: Class
title: Algae
subclass of: BiomassFeedstockType
alternative label: Microalgae
definition: Microalgae or macroalgae cultivated for lipid or carbohydrate content for biofuel production.
category: aquatic_biomass
lipid rich: true

ANIMAL_MANURE
type: Class
title: Animal Manure
subclass of: BiomassFeedstockType
definition: Livestock waste including cattle, swine, and poultry manure.
related match: ENVO_00003031
biogas suitable: true
category: wet_waste

CORN_GRAIN
type: Class
title: Corn Grain
subclass of: BiomassFeedstockType
definition: Corn kernels used for starch-based ethanol production.
category: grain
starch crop: true

CORN_STOVER
type: Class
title: Corn Stover
subclass of: BiomassFeedstockType
alternative label: Corn Residue
definition: Agricultural residue consisting of leaves, stalks, and cobs remaining after corn grain harvest.
category: agricultural_residue
lignocellulosic: true

ENERGY_CANE
type: Class
title: Energy Cane
subclass of: BiomassFeedstockType
definition: High-fiber sugarcane varieties bred for biomass production rather than sugar content.
category: energy_crop
lignocellulosic: true

FOOD_WASTE
type: Class
title: Food Waste
subclass of: BiomassFeedstockType
definition: Waste food from residential, commercial, and industrial sources.
category: wet_waste

FOREST_RESIDUE
type: Class
title: Forest Residue
subclass of: BiomassFeedstockType
alternative label: Logging Residue
broad match: Biomass
definition: Biomass from forest operations including logging residues, thinning material, and salvage timber.
related match: AGRO_00000546
category: forestry_residue
lignocellulosic: true

MISCANTHUS
type: Class
title: Miscanthus
subclass of: BiomassFeedstockType
alternative label: Elephant Grass
definition: High-yielding perennial grass cultivated as dedicated energy crop.
category: energy_crop
lignocellulosic: true
perennial: true

MUNICIPAL_SOLID_WASTE
type: Class
title: Municipal Solid Waste (Organic Fraction)
subclass of: BiomassFeedstockType
alternative label: MSW
definition: Organic portion of municipal solid waste suitable for bioenergy conversion.
related match: ENVO_00002273
category: waste

POPLAR
type: Class
title: Poplar
subclass of: BiomassFeedstockType
alternative label: Hybrid Poplar
definition: Fast-growing hardwood tree cultivated as short-rotation woody crop for biomass.
category: woody_crop
lignocellulosic: true

RICE_STRAW
type: Class
title: Rice Straw
subclass of: BiomassFeedstockType
definition: Agricultural residue remaining after rice grain harvest.
category: agricultural_residue
lignocellulosic: true

SUGARCANE
type: Class
title: Sugarcane
subclass of: BiomassFeedstockType
definition: Sugar-rich crop used for first-generation ethanol production.
category: sugar_crop

SWEET_SORGHUM
type: Class
title: Sweet Sorghum
subclass of: BiomassFeedstockType
definition: Sorghum variety with high sugar content in stalks, suitable for both sugar and lignocellulosic conversion.
category: energy_crop
sugar crop: true

SWITCHGRASS
type: Class
title: Switchgrass
subclass of: BiomassFeedstockType
definition: Perennial warm-season grass native to North America, cultivated as dedicated energy crop for cellulosic biofuel production.
related match: AGRO_00000325
category: energy_crop
lignocellulosic: true
perennial: true

USED_COOKING_OIL
type: Class
title: Used Cooking Oil
subclass of: BiomassFeedstockType
alternative label: UCO
alternative label: Waste Vegetable Oil
definition: Waste vegetable oils from food preparation.
category: waste
lipid rich: true

WHEAT_STRAW
type: Class
title: Wheat Straw
subclass of: BiomassFeedstockType
definition: Agricultural residue remaining after wheat grain harvest.
category: agricultural_residue
lignocellulosic: true

WILLOW
type: Class
title: Willow
subclass of: BiomassFeedstockType
alternative label: Shrub Willow
definition: Fast-growing shrub cultivated as short-rotation woody crop.
category: woody_crop
lignocellulosic: true

WOOD_PROCESSING_RESIDUE
type: Class
title: Wood Processing Residue
subclass of: BiomassFeedstockType
alternative label: Mill Residue
definition: Byproducts from wood processing including sawdust, bark, shavings, and wood chips.
category: processing_residue
lignocellulosic: true

CONTINUOUS_PROCESSING
type: Class
subclass of: BioprocessOptimizationType
definition: Conversion from batch to continuous operation for improved efficiency and consistency

DIGITAL_TWIN_MODELING
type: Class
subclass of: BioprocessOptimizationType
definition: Use of computational process models for simulation, prediction, and optimization
approaches: mechanistic models, hybrid models, machine learning

DOWNSTREAM_PURIFICATION
type: Class
subclass of: BioprocessOptimizationType
broad match: OBI_0001505
definition: Optimization of product recovery and purification processes
approaches: chromatography, membrane separation, extraction

FED_BATCH_OPTIMIZATION
type: Class
subclass of: BioprocessOptimizationType
definition: Optimization of feeding strategies in fed-batch processes to maximize product yield

IN_LINE_ANALYTICS
type: Class
subclass of: BioprocessOptimizationType
definition: Implementation of real-time process analytical technology (PAT) for process monitoring and control
technologies: Raman spectroscopy, NIR, online HPLC

MEDIA_OPTIMIZATION
type: Class
subclass of: BioprocessOptimizationType
definition: Optimization of growth media composition including carbon sources, nitrogen sources, and micronutrients

PROCESS_INTENSIFICATION
type: Class
subclass of: BioprocessOptimizationType
definition: Engineering approaches to increase volumetric productivity and reduce process footprint

STRAIN_ENGINEERING
type: Class
subclass of: BioprocessOptimizationType
definition: Genetic modification and selection of production strains for improved performance
approaches: metabolic engineering, directed evolution, adaptive laboratory evolution

BioprocessingDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for bioprocessing value sets
in scheme: merged

BIOACTIVE_COMPOUND
type: Class
subclass of: BioproductCategoryType
definition: Biologically active compounds with therapeutic or functional properties
examples: alkaloids, terpenoids, flavonoids

BIOCHEMICAL
type: Class
subclass of: BioproductCategoryType
definition: Chemical compounds produced through biological processes
related match: CHEBI_52206
examples: organic acids, amino acids, platform chemicals

BIOPESTICIDE
type: Class
subclass of: BioproductCategoryType
broad match: CHEBI_25944
definition: Biological agents used for pest control in agriculture
examples: Bacillus thuringiensis, entomopathogenic fungi

BIOPLASTIC
type: Class
subclass of: BioproductCategoryType
definition: Biodegradable or bio-based plastic materials such as PHA, PLA, and PBS
examples: polyhydroxyalkanoates, polylactic acid

BIOSURFACTANT
type: Class
subclass of: BioproductCategoryType
definition: Surface-active compounds produced by microorganisms
related match: CHEBI_35195
examples: rhamnolipids, sophorolipids, surfactin

AIRLIFT
type: Class
subclass of: BioreactorTypeEnum
definition: Airlift bioreactor
related match: ENVO_00002125
related match: OBI_0001046
advantages: Low shear, no mechanical parts
mixing: Gas sparging

BUBBLE_COLUMN
type: Class
subclass of: BioreactorTypeEnum
definition: Bubble column bioreactor
related match: OBI_0001046
advantages: Simple design, good mass transfer
mixing: Gas bubbling

FLUIDIZED_BED
type: Class
subclass of: BioreactorTypeEnum
definition: Fluidized bed bioreactor
configuration: Suspended solid particles
mixing: Fluid flow

HOLLOW_FIBER
type: Class
subclass of: BioreactorTypeEnum
definition: Hollow fiber bioreactor
application: High-density cell culture
configuration: Hollow fiber membranes

PACKED_BED
type: Class
subclass of: BioreactorTypeEnum
definition: Packed bed bioreactor
configuration: Fixed bed of immobilized cells/enzymes
flow: Continuous

PHOTOBIOREACTOR
type: Class
subclass of: BioreactorTypeEnum
definition: Photobioreactor for photosynthetic organisms
light source: Required
organisms: Algae, cyanobacteria

STIRRED_TANK
type: Class
subclass of: BioreactorTypeEnum
definition: Stirred tank reactor (STR/CSTR)
related match: OBI_0001046
common volumes: 1-200000 L
mixing: Mechanical agitation

WAVE_BAG
type: Class
subclass of: BioreactorTypeEnum
definition: Wave/rocking bioreactor
advantages: Single-use, low shear
mixing: Rocking motion

HYDROGEN
type: Class
subclass of: BondTypeEnum
definition: Hydrogen bond
energy: 5-30 kJ/mol
type: weak interaction

METALLIC
type: Class
subclass of: BondTypeEnum
definition: Metallic bond
type: delocalized electrons

PI
type: Class
subclass of: BondTypeEnum
definition: Pi bond
orbital overlap: side-to-side

SIGMA
type: Class
subclass of: BondTypeEnum
definition: Sigma bond
orbital overlap: head-to-head

VAN_DER_WAALS
type: Class
subclass of: BondTypeEnum
definition: Van der Waals interaction
energy: 0.4-4 kJ/mol
type: weak interaction

BASE_CENTERED_MONOCLINIC
type: Class
title: Base-Centered Monoclinic
subclass of: BravaisLatticeEnum
alternative label: mC
alternative label: mS
definition: Base-centered monoclinic lattice (mC)

BASE_CENTERED_ORTHORHOMBIC
type: Class
title: Base-Centered Orthorhombic
subclass of: BravaisLatticeEnum
alternative label: oC
alternative label: oS
definition: Base-centered orthorhombic lattice (oC)

BODY_CENTERED_CUBIC
type: Class
title: Body-Centered Cubic
subclass of: BravaisLatticeEnum
alternative label: BCC
alternative label: cI
definition: Body-centered cubic lattice (cI)

BODY_CENTERED_ORTHORHOMBIC
type: Class
title: Body-Centered Orthorhombic
subclass of: BravaisLatticeEnum
alternative label: oI
definition: Body-centered orthorhombic lattice (oI)

BODY_CENTERED_TETRAGONAL
type: Class
title: Body-Centered Tetragonal
subclass of: BravaisLatticeEnum
alternative label: tI
definition: Body-centered tetragonal lattice (tI)

FACE_CENTERED_CUBIC
type: Class
title: Face-Centered Cubic
subclass of: BravaisLatticeEnum
alternative label: FCC
alternative label: cF
definition: Face-centered cubic lattice (cF)

FACE_CENTERED_ORTHORHOMBIC
type: Class
title: Face-Centered Orthorhombic
subclass of: BravaisLatticeEnum
alternative label: oF
definition: Face-centered orthorhombic lattice (oF)

PRIMITIVE_CUBIC
type: Class
title: Primitive Cubic
subclass of: BravaisLatticeEnum
alternative label: SC
alternative label: cP
definition: Simple cubic lattice (cP)

PRIMITIVE_HEXAGONAL
type: Class
title: Primitive Hexagonal
subclass of: BravaisLatticeEnum
alternative label: hP
definition: Primitive hexagonal lattice (hP)

PRIMITIVE_MONOCLINIC
type: Class
title: Primitive Monoclinic
subclass of: BravaisLatticeEnum
alternative label: mP
definition: Primitive monoclinic lattice (mP)

PRIMITIVE_ORTHORHOMBIC
type: Class
title: Primitive Orthorhombic
subclass of: BravaisLatticeEnum
alternative label: oP
definition: Primitive orthorhombic lattice (oP)

PRIMITIVE_TETRAGONAL
type: Class
title: Primitive Tetragonal
subclass of: BravaisLatticeEnum
alternative label: tP
definition: Primitive tetragonal lattice (tP)

PRIMITIVE_TRICLINIC
type: Class
title: Primitive Triclinic
subclass of: BravaisLatticeEnum
alternative label: aP
definition: Primitive triclinic lattice (aP)

PRIMITIVE_TRIGONAL
type: Class
title: Primitive Trigonal
subclass of: BravaisLatticeEnum
alternative label: hR
definition: Primitive trigonal/rhombohedral lattice (hR)

AMPHOTERIC
type: Class
subclass of: BronstedAcidBaseRoleEnum
definition: Can act as both acid and base
definition: species that can donate or accept H+
examples: H2O, HSO4-, H2PO4-

CODE_MINIMUM
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: Building meeting minimum energy code requirements without additional certification

ENERGY_STAR_CERTIFIED
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: EPA Energy Star certification for buildings performing in top 25% of energy efficiency

LEED_CERTIFIED
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: LEED Certified rating (40-49 points) from the U.S. Green Building Council

LEED_GOLD
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: LEED Gold rating (60-79 points) from the U.S. Green Building Council

LEED_PLATINUM
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: LEED Platinum rating (80+ points) from the U.S. Green Building Council

LEED_SILVER
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: LEED Silver rating (50-59 points) from the U.S. Green Building Council

NET_POSITIVE_ENERGY
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: Building that produces more energy than it consumes on an annual basis

NET_ZERO_ENERGY
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: Building that produces as much energy as it consumes on an annual basis

PASSIVE_HOUSE
type: Class
subclass of: BuildingEnergyPerformanceLevel
definition: Building meeting Passive House Institute standards for ultra-low energy consumption

BREEAM_EXCELLENT
type: Class
subclass of: BuildingEnergyStandard
definition: BREEAM Excellent

BREEAM_GOOD
type: Class
subclass of: BuildingEnergyStandard
definition: BREEAM Good

BREEAM_OUTSTANDING
type: Class
subclass of: BuildingEnergyStandard
definition: BREEAM Outstanding

BREEAM_PASS
type: Class
subclass of: BuildingEnergyStandard
definition: BREEAM Pass

BREEAM_VERY_GOOD
type: Class
subclass of: BuildingEnergyStandard
definition: BREEAM Very Good

ENERGY_POSITIVE
type: Class
subclass of: BuildingEnergyStandard
definition: Energy Positive Building

LEED_CERTIFIED
type: Class
subclass of: BuildingEnergyStandard
definition: LEED Certified

LEED_GOLD
type: Class
subclass of: BuildingEnergyStandard
definition: LEED Gold certification

LEED_PLATINUM
type: Class
subclass of: BuildingEnergyStandard
definition: LEED Platinum certification

LEED_SILVER
type: Class
subclass of: BuildingEnergyStandard
definition: LEED Silver certification

NET_ZERO
type: Class
subclass of: BuildingEnergyStandard
definition: Net Zero Energy Building

PASSIVE_HOUSE
type: Class
subclass of: BuildingEnergyStandard
definition: Passive House (Passivhaus) standard

ZERO_CARBON
type: Class
subclass of: BuildingEnergyStandard
definition: Zero Carbon Building

BUILDING_AUTOMATION
type: Class
subclass of: BuildingSystemType
definition: Integrated control systems for monitoring and managing building operations

ELECTRICAL
type: Class
subclass of: BuildingSystemType
definition: Electrical power distribution and wiring systems within the building

FIRE_PROTECTION
type: Class
subclass of: BuildingSystemType
definition: Fire detection, suppression, and alarm systems

HVAC
type: Class
subclass of: BuildingSystemType
definition: Heating, ventilation, and air conditioning systems for climate control

LIGHTING
type: Class
subclass of: BuildingSystemType
definition: Interior and exterior lighting systems including controls and fixtures

PLUMBING
type: Class
subclass of: BuildingSystemType
definition: Water supply, drainage, and sewage systems

RENEWABLE_ENERGY_INTEGRATION
type: Class
subclass of: BuildingSystemType
definition: On-site renewable energy generation systems such as solar panels and wind turbines

STRUCTURAL
type: Class
subclass of: BuildingSystemType
definition: Load-bearing structural framework including foundations, columns, beams, and slabs

DISTRIBUTION
type: Class
title: Distribution/Trade
subclass of: BusinessActivityTypeEnum
definition: Moving goods from producers to consumers
efficiency: improves market efficiency
examples: wholesalers, retailers, logistics companies
function: intermediary between producers and consumers
value added: place and time utility

EDUCATION
type: Class
title: Education/Training
subclass of: BusinessActivityTypeEnum
definition: Providing educational and training services
examples: schools, universities, training companies
function: knowledge and skill development
public private: public and private providers
social impact: high social impact

ENTERTAINMENT
type: Class
title: Entertainment/Recreation
subclass of: BusinessActivityTypeEnum
definition: Providing entertainment and recreational services
discretionary: discretionary consumer spending
examples: media, sports, tourism, gaming
experience based: experience and emotion based
output: entertainment and leisure experiences

FINANCE
type: Class
title: Financial Services
subclass of: BusinessActivityTypeEnum
definition: Providing financial and investment services
capital: capital intensive
examples: banks, insurance, investment firms
function: financial intermediation and services
regulation: highly regulated

HEALTHCARE
type: Class
title: Healthcare/Medical
subclass of: BusinessActivityTypeEnum
definition: Providing health and medical services
essential: essential service
examples: hospitals, clinics, pharmaceutical companies
function: health and medical care
regulation: highly regulated

INFORMATION
type: Class
title: Information/Media
subclass of: BusinessActivityTypeEnum
definition: Creating, processing, and distributing information
channels: various distribution channels
examples: media companies, publishers, data processors
output: information and content
technology dependent: technology platform dependent

PRODUCTION
type: Class
title: Production/Manufacturing
subclass of: BusinessActivityTypeEnum
definition: Creating or manufacturing physical goods
assets: physical assets and equipment intensive
examples: factories, farms, mines
output: physical products and goods
process: transformation of materials

PROFESSIONAL_SERVICES
type: Class
title: Professional Services
subclass of: BusinessActivityTypeEnum
definition: Providing specialized professional expertise
characteristics: high skill and knowledge requirements
customization: highly customized services
examples: law firms, consulting, accounting
expertise: specialized professional expertise

SERVICES
type: Class
title: Service Provision
subclass of: BusinessActivityTypeEnum
definition: Providing intangible services to customers
characteristics: labor intensive, customized
customer interaction: high customer interaction
examples: consulting, healthcare, hospitality
output: intangible services

TECHNOLOGY
type: Class
title: Technology/Innovation
subclass of: BusinessActivityTypeEnum
definition: Developing and applying technology solutions
examples: software companies, biotech, engineering
focus: technology development and application
innovation: research and development intensive
intellectual property: high intellectual property content

CONCEPT_STAGE
type: Class
title: Concept Stage
subclass of: BusinessLifecycleStageEnum
definition: Initial business idea development and validation
activities: market research, business planning
focus: idea development and validation
funding: personal or angel funding
risk: highest risk level

DECLINE_STAGE
type: Class
title: Decline Stage
subclass of: BusinessLifecycleStageEnum
definition: Decreasing market relevance or performance
activities: turnaround efforts or exit planning
challenges: declining revenues or relevance
focus: cost reduction and restructuring
options: restructuring, sale, or closure

EXIT_STAGE
type: Class
title: Exit Stage
subclass of: BusinessLifecycleStageEnum
definition: Business sale, merger, or closure
activities: sale, merger, or liquidation
focus: exit strategy execution
transition: ownership transition
valuation: business valuation

EXPANSION_STAGE
type: Class
title: Expansion Stage
subclass of: BusinessLifecycleStageEnum
definition: Market expansion and diversification
activities: new markets, products, or services
focus: market expansion and diversification
funding: growth capital, strategic investments
sophistication: increased operational sophistication

GROWTH_STAGE
type: Class
title: Growth Stage
subclass of: BusinessLifecycleStageEnum
definition: Rapid expansion and scaling operations
activities: increasing market share
challenges: scaling challenges
focus: scaling operations and market expansion
funding: venture capital, growth financing

MATURITY_STAGE
type: Class
title: Maturity Stage
subclass of: BusinessLifecycleStageEnum
definition: Stable operations with established market position
activities: defending market position
focus: operational efficiency and market defense
funding: self-funding, debt financing
stability: stable cash flows

STARTUP_STAGE
type: Class
title: Startup Stage
subclass of: BusinessLifecycleStageEnum
definition: Business launch and early operations
activities: building initial customer base
focus: product development and market entry
funding: seed funding, early investments
growth: rapid learning and adaptation

TURNAROUND_STAGE
type: Class
title: Turnaround Stage
subclass of: BusinessLifecycleStageEnum
definition: Recovery efforts from decline or crisis
activities: restructuring and repositioning
focus: crisis management and recovery
leadership: turnaround management
urgency: urgent transformation needs

EMPLOYEE_OWNERSHIP
type: Class
title: Employee Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned by employees through stock or cooperative structure
alignment: ownership-management alignment
ownership: employee owners
participation: employee participation
structure: ESOP or cooperative structure

FAMILY_OWNERSHIP
type: Class
title: Family Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned and controlled by family members
long term: long-term orientation
ownership: family members
succession: family succession planning
values: family values integration

FOREIGN_OWNERSHIP
type: Class
title: Foreign Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned by foreign individuals or entities
capital: foreign capital
compliance: international compliance
ownership: foreign entities
regulation: foreign investment regulations

GOVERNMENT_OWNERSHIP
type: Class
title: Government Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned by government entities
funding: public funding
ownership: government entities
purpose: public policy objectives
regulation: government oversight

INSTITUTIONAL_OWNERSHIP
type: Class
title: Institutional Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned by institutional investors
capital: institutional capital
governance: institutional governance
ownership: institutional investors
professional: professional management

JOINT_OWNERSHIP
type: Class
title: Joint Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned jointly by multiple parties
agreements: joint ownership agreements
coordination: ownership coordination
governance: shared governance
ownership: multiple ownership parties

PRIVATE_OWNERSHIP
type: Class
title: Private Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business owned by private individuals or entities
capital: private capital sources
control: private control
disclosure: limited disclosure requirements
ownership: private individuals or entities

PUBLIC_OWNERSHIP
type: Class
title: Public Ownership
subclass of: BusinessOwnershipTypeEnum
definition: Business with publicly traded ownership shares
disclosure: public disclosure requirements
ownership: public shareholders
regulation: extensive regulatory requirements
trading: publicly traded shares

CORE_PROCESS
type: Class
title: Core Business Process
subclass of: BusinessProcessTypeEnum
definition: Primary processes that create customer value
competitive: competitive advantage source
primary: primary business activities
strategic: strategic importance
value: direct customer value creation

CUSTOMER_PROCESS
type: Class
title: Customer Process
subclass of: BusinessProcessTypeEnum
definition: Processes focused on customer interaction and service
customer: customer-facing processes
relationship: customer relationship
satisfaction: customer satisfaction
service: customer service

FINANCIAL_PROCESS
type: Class
title: Financial Process
subclass of: BusinessProcessTypeEnum
definition: Processes related to financial management
accounting: accounting and reporting
compliance: financial compliance
control: financial control
financial: financial management

INNOVATION_PROCESS
type: Class
title: Innovation Process
subclass of: BusinessProcessTypeEnum
definition: Processes for developing new products or services
competitive: competitive innovation
creativity: creative processes
innovation: innovation and development
new development: new product/service development

MANAGEMENT_PROCESS
type: Class
title: Management Process
subclass of: BusinessProcessTypeEnum
definition: Processes for planning, controlling, and improving
improvement: process improvement
management: management and governance
oversight: organizational oversight
planning: planning and control

OPERATIONAL_PROCESS
type: Class
title: Operational Process
subclass of: BusinessProcessTypeEnum
definition: Day-to-day operational activities
efficiency: operational efficiency
execution: operational execution
operations: daily operations
routine: routine activities

STRATEGIC_PROCESS
type: Class
title: Strategic Process
subclass of: BusinessProcessTypeEnum
definition: Long-term planning and strategic activities
competitive: competitive positioning
direction: organizational direction
long term: long-term focus
strategy: strategic planning

SUPPORT_PROCESS
type: Class
title: Support Process
subclass of: BusinessProcessTypeEnum
definition: Processes that enable core business activities
enabling: enabling activities
indirect: indirect value contribution
infrastructure: business infrastructure
support: supports core processes

FORTUNE_500
type: Class
title: Fortune 500 Company
subclass of: BusinessSizeClassificationEnum
definition: Among the 500 largest US corporations by revenue
market position: market leadership positions
ranking: Fortune 500 list
recognition: prestigious business recognition
revenue: highest revenue levels

LARGE_BUSINESS
type: Class
title: Large Business
subclass of: BusinessSizeClassificationEnum
definition: Major corporation with significant operations
employees: >1500 employees
market presence: national or international presence
revenue: high revenue levels
structure: complex organizational structure

MEDIUM_BUSINESS
type: Class
title: Medium Business
subclass of: BusinessSizeClassificationEnum
definition: Mid-sized business between small and large classifications
characteristics: regional or specialized market presence
employees: typically 500-1500 employees
revenue: moderate revenue levels
structure: more formal organizational structure

MICRO_BUSINESS
type: Class
title: Micro Business
subclass of: BusinessSizeClassificationEnum
definition: Very small business with minimal employees and revenue
characteristics: home-based or small office
employees: typically 1-9 employees
revenue: very low revenue
support: minimal administrative support

MULTINATIONAL_CORPORATION
type: Class
title: Multinational Corporation
subclass of: BusinessSizeClassificationEnum
definition: Large corporation operating in multiple countries
complexity: high operational complexity
coordination: international coordination
geographic scope: multiple countries
structure: global organizational structure

SMALL_BUSINESS
type: Class
title: Small Business
subclass of: BusinessSizeClassificationEnum
definition: Small business as defined by SBA standards
characteristics: independently owned and operated
employees: varies by industry (typically <500)
revenue: varies by industry
sba definition: meets SBA size standards

END_OF_DAY
type: Class
subclass of: BusinessTimeFrame
definition: End of business day
abbreviation: EOD

END_OF_MONTH
type: Class
subclass of: BusinessTimeFrame
definition: End of calendar month
abbreviation: EOM

END_OF_QUARTER
type: Class
subclass of: BusinessTimeFrame
definition: End of calendar quarter
abbreviation: EOQ

END_OF_WEEK
type: Class
subclass of: BusinessTimeFrame
definition: End of business week
abbreviation: EOW

END_OF_YEAR
type: Class
subclass of: BusinessTimeFrame
definition: End of calendar year
abbreviation: EOY

INTRADAY
type: Class
subclass of: BusinessTimeFrame
definition: Within the same day

MONTH_TO_DATE
type: Class
subclass of: BusinessTimeFrame
definition: From beginning of month to current date
abbreviation: MTD

QUARTER_TO_DATE
type: Class
subclass of: BusinessTimeFrame
definition: From beginning of quarter to current date
abbreviation: QTD

REAL_TIME
type: Class
subclass of: BusinessTimeFrame
definition: Real-time/instantaneous

T_PLUS_1
type: Class
subclass of: BusinessTimeFrame
definition: Trade date plus one business day
abbreviation: T+1

T_PLUS_2
type: Class
subclass of: BusinessTimeFrame
definition: Trade date plus two business days
abbreviation: T+2

T_PLUS_3
type: Class
subclass of: BusinessTimeFrame
definition: Trade date plus three business days
abbreviation: T+3

YEAR_TO_DATE
type: Class
subclass of: BusinessTimeFrame
definition: From beginning of year to current date
abbreviation: YTD

AB
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Alberta

BC
type: Class
subclass of: CanadianProvinceCodeEnum
definition: British Columbia

MB
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Manitoba

NB
type: Class
subclass of: CanadianProvinceCodeEnum
definition: New Brunswick

NL
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Newfoundland and Labrador

NS
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Nova Scotia

NT
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Northwest Territories

NU
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Nunavut

PE
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Prince Edward Island

QC
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Quebec

SK
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Saskatchewan

True
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Ontario

YT
type: Class
subclass of: CanadianProvinceCodeEnum
definition: Yukon

LEVEL_1
type: Class
title: Level 1 - Initial
subclass of: CapabilityMaturityLevel
definition: Initial - Processes are unpredictable, poorly controlled, and reactive

LEVEL_2
type: Class
title: Level 2 - Managed
subclass of: CapabilityMaturityLevel
definition: Managed - Processes are characterized for projects and reactive

LEVEL_3
type: Class
title: Level 3 - Defined
subclass of: CapabilityMaturityLevel
definition: Defined - Processes are characterized for the organization and proactive

LEVEL_4
type: Class
title: Level 4 - Quantitatively Managed
subclass of: CapabilityMaturityLevel
definition: Quantitatively Managed - Processes are measured and controlled

LEVEL_5
type: Class
title: Level 5 - Optimizing
subclass of: CapabilityMaturityLevel
definition: Optimizing - Focus on continuous process improvement

COMING_ONLINE
type: Class
title: Coming Online
subclass of: CapabilityStatus
definition: Being commissioned, coming online soon
related match: Q811686
iaea equivalent: commissioning
lifecycle phase: commissioning
wikidata label: building process

DECOMMISSIONED
type: Class
title: Decommissioned
subclass of: CapabilityStatus
definition: No longer available, permanently shut down
related match: Discontinued
iaea equivalent: decommissioned
lifecycle phase: end-of-life

OPERATIONAL
type: Class
title: Operational
subclass of: CapabilityStatus
definition: Fully operational and available to users
lifecycle phase: operation
wikidata label: in use

PILOT
type: Class
title: Pilot
subclass of: CapabilityStatus
definition: In pilot phase with limited access
related match: LimitedAvailability
availability: limited
lifecycle phase: testing

UNDER_DEVELOPMENT
type: Class
title: Under Development
subclass of: CapabilityStatus
definition: Under development, not yet available
lifecycle phase: planning/construction
wikidata label: proposed building or structure

HIGH_CARBON
type: Class
subclass of: CarbonIntensity
definition: High carbon (500-1000 gCO2/kWh)
g CO2 per k wh: 500-1000

LOW_CARBON
type: Class
subclass of: CarbonIntensity
definition: Low carbon (50-200 gCO2/kWh)
g CO2 per k wh: 50-200

MEDIUM_CARBON
type: Class
subclass of: CarbonIntensity
definition: Medium carbon (200-500 gCO2/kWh)
g CO2 per k wh: 200-500

VERY_HIGH_CARBON
type: Class
subclass of: CarbonIntensity
definition: Very high carbon (> 1000 gCO2/kWh)
g CO2 per k wh: 1000+

VERY_LOW_CARBON
type: Class
subclass of: CarbonIntensity
definition: Very low carbon (< 50 gCO2/kWh)
g CO2 per k wh: 0-50

ZERO_CARBON
type: Class
subclass of: CarbonIntensity
definition: Zero carbon emissions
g CO2 per k wh: 0

CaseOrControlEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Case Or Control
status: DRAFT
subclass of: InvestigationSchemaEnum
union of: CASE
union of: CONTROL
definition: Enum: CaseOrControlEnum
in scheme: merged
permissible values: CASE
permissible values: CONTROL
source domain: root
source schema: investigation

ACID
type: Class
subclass of: CatalystTypeEnum
definition: Acid catalyst
mechanism: proton donation

BASE
type: Class
subclass of: CatalystTypeEnum
definition: Base catalyst
mechanism: proton abstraction

BIFUNCTIONAL
type: Class
subclass of: CatalystTypeEnum
definition: Catalyst with two active sites
sites: multiple

HETEROGENEOUS
type: Class
subclass of: CatalystTypeEnum
definition: Catalyst in different phase from reactants
examples: Pt/Pd on carbon, zeolites
phase: different from reactants

HOMOGENEOUS
type: Class
subclass of: CatalystTypeEnum
definition: Catalyst in same phase as reactants
examples: acid, base, metal complexes
phase: same as reactants

METAL
type: Class
subclass of: CatalystTypeEnum
definition: Metal catalyst
examples: Pd, Pt, Ni, Ru

ORGANOCATALYST
type: Class
subclass of: CatalystTypeEnum
definition: Small organic molecule catalyst
examples: proline, thiourea
metal free: true

PHASE_TRANSFER
type: Class
subclass of: CatalystTypeEnum
definition: Catalyst facilitating reaction between phases
function: transfers reactant between phases

PHOTOCATALYST
type: Class
subclass of: CatalystTypeEnum
definition: Light-activated catalyst
activation: light
examples: TiO2, Ru complexes

PHASE_0
type: Class
title: 0
subclass of: CdsPhaseType
definition: Zero bases from reading frame to feature start.

PHASE_1
type: Class
title: 1
subclass of: CdsPhaseType
definition: One base from reading frame to feature start.

PHASE_2
type: Class
title: 2
subclass of: CdsPhaseType
definition: Two bases from reading frame to feature start.

ALAMAR_BLUE_ABSORBANCE
type: Class
subclass of: CellBasedAssayEnum
alternative label: 2D AlamarBlue absorbance
definition: AlamarBlue absorbance assay (2D)

ALAMAR_BLUE_FLUORESCENCE
type: Class
subclass of: CellBasedAssayEnum
alternative label: 2D AlamarBlue fluorescence
definition: AlamarBlue fluorescence assay (2D)

ARRAY
type: Class
subclass of: CellBasedAssayEnum
definition: General array-based assay

ATPASE_ACTIVITY_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: ATPase activity measurement

CALCIUM_RETENTION_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Calcium retention capacity assay

CAMP_GLO_ASSAY
type: Class
subclass of: CellBasedAssayEnum
alternative label: cAMP-Glo Max Assay
definition: cAMP-Glo Max Assay

CELL_PERMEABILITY_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Cell permeability assay

COMBINATION_SCREEN
type: Class
subclass of: CellBasedAssayEnum
definition: Drug combination screening

COMPOUND_SCREEN
type: Class
subclass of: CellBasedAssayEnum
definition: Compound library screening

CURRENT_CLAMP_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Current clamp electrophysiology

EDU_PROLIFERATION
type: Class
subclass of: CellBasedAssayEnum
alternative label: EdU proliferation assay
definition: EdU incorporation proliferation assay

ELECTROCHEMILUMINESCENCE
type: Class
subclass of: CellBasedAssayEnum
definition: Electrochemiluminescence detection

FOCUS_FORMING_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Focus forming assay

IN_VITRO_TUMORIGENESIS
type: Class
subclass of: CellBasedAssayEnum
definition: In vitro tumorigenesis assay

IN_VIVO_PDX_VIABILITY
type: Class
subclass of: CellBasedAssayEnum
definition: In vivo patient-derived xenograft viability

IN_VIVO_TUMOR_GROWTH
type: Class
subclass of: CellBasedAssayEnum
definition: In vivo tumor growth assay

LOCAL_FIELD_POTENTIAL
type: Class
subclass of: CellBasedAssayEnum
definition: Local field potential recording

LONG_TERM_POTENTIATION
type: Class
subclass of: CellBasedAssayEnum
definition: Long-term potentiation assay

MASSIVELY_PARALLEL_REPORTER_ASSAY
type: Class
subclass of: CellBasedAssayEnum
alternative label: MPRA
definition: Massively parallel reporter assay

MATRIGEL_TUMORIGENESIS
type: Class
subclass of: CellBasedAssayEnum
alternative label: Matrigel-based tumorigenesis assay
definition: Matrigel-based tumorigenesis assay

NANOSTRING_NCOUNTER
type: Class
subclass of: CellBasedAssayEnum
definition: NanoString nCounter Analysis System

PHARMACOKINETIC_ADME
type: Class
subclass of: CellBasedAssayEnum
alternative label: pharmocokinetic ADME assay
definition: Pharmacokinetic ADME assay

ROS_ASSAY
type: Class
subclass of: CellBasedAssayEnum
alternative label: reactive oxygen species assay
definition: Reactive oxygen species assay

SANDWICH_ELISA
type: Class
subclass of: CellBasedAssayEnum
definition: Sandwich ELISA

SMALL_MOLECULE_LIBRARY_SCREEN
type: Class
subclass of: CellBasedAssayEnum
definition: Small molecule library screen

SPLIT_GFP_ASSAY
type: Class
subclass of: CellBasedAssayEnum
alternative label: split-GFP assay
definition: Split-GFP protein interaction assay

STR_PROFILE
type: Class
subclass of: CellBasedAssayEnum
definition: Short tandem repeat profiling

SURVIVAL_ASSAY
type: Class
subclass of: CellBasedAssayEnum
definition: Cell or organism survival assay

THREE_D_MICROTISSUE_VIABILITY
type: Class
subclass of: CellBasedAssayEnum
alternative label: 3D microtissue viability
definition: 3D microtissue viability assay

TIDE
type: Class
subclass of: CellBasedAssayEnum
definition: Tracking of Indels by Decomposition

TRANS_ENDOTHELIAL_RESISTANCE
type: Class
subclass of: CellBasedAssayEnum
alternative label: trans-endothelial electrical resistance
definition: Trans-endothelial electrical resistance measurement

APICAL
type: Class
subclass of: CellPolarity
definition: The free surface of an epithelial cell
location: typically faces lumen or external environment

APICAL_LATERAL
type: Class
subclass of: CellPolarity
definition: Junction between apical and lateral surfaces

BASAL
type: Class
subclass of: CellPolarity
definition: The attached surface of an epithelial cell
location: typically attached to basement membrane

BASAL_LATERAL
type: Class
subclass of: CellPolarity
definition: Junction between basal and lateral surfaces

DISTAL_POLE
type: Class
subclass of: CellPolarity
definition: Pole further from the cell body
context: neurons, polarized cells

LATERAL
type: Class
subclass of: CellPolarity
definition: The sides of an epithelial cell
location: faces neighboring cells

LEADING_EDGE
type: Class
subclass of: CellPolarity
definition: Front of a migrating cell
context: cell migration

PROXIMAL_POLE
type: Class
subclass of: CellPolarity
definition: Pole closer to the cell body
context: neurons, polarized cells

TRAILING_EDGE
type: Class
subclass of: CellPolarity
definition: Rear of a migrating cell
context: cell migration

MATURE_NODE
type: Class
subclass of: ChipFabricationNodeType
definition: Mature fabrication node (65nm and larger) for legacy and specialty applications
feature size: 65nm+

NODE_10NM
type: Class
subclass of: ChipFabricationNodeType
definition: 10 nanometer process node
feature size: 10nm

NODE_14NM
type: Class
subclass of: ChipFabricationNodeType
definition: 14 nanometer process node
feature size: 14nm

NODE_22NM
type: Class
subclass of: ChipFabricationNodeType
definition: 22 nanometer process node
feature size: 22nm

NODE_28NM
type: Class
subclass of: ChipFabricationNodeType
definition: 28 nanometer process node
feature size: 28nm

NODE_3NM
type: Class
subclass of: ChipFabricationNodeType
definition: 3 nanometer process node
feature size: 3nm

NODE_45NM
type: Class
subclass of: ChipFabricationNodeType
definition: 45 nanometer process node
feature size: 45nm

NODE_5NM
type: Class
subclass of: ChipFabricationNodeType
definition: 5 nanometer process node
feature size: 5nm

NODE_7NM
type: Class
subclass of: ChipFabricationNodeType
definition: 7 nanometer process node
feature size: 7nm

D
type: Class
subclass of: ChiralityEnum
definition: Dextrorotatory
fischer projection: true
optical rotation: positive

E
type: Class
subclass of: ChiralityEnum
definition: Entgegen (opposite) configuration
geometric isomer: true

L
type: Class
subclass of: ChiralityEnum
definition: Levorotatory
fischer projection: true
optical rotation: negative

MESO
type: Class
subclass of: ChiralityEnum
definition: Meso compound (achiral despite stereocenters)
internal symmetry: true

R
type: Class
subclass of: ChiralityEnum
definition: Rectus (right) configuration
cahn ingold prelog: true

RACEMIC
type: Class
subclass of: ChiralityEnum
definition: Racemic mixture (50:50 of enantiomers)
optical rotation: zero

S
type: Class
subclass of: ChiralityEnum
definition: Sinister (left) configuration
cahn ingold prelog: true

Z
type: Class
subclass of: ChiralityEnum
definition: Zusammen (together) configuration
geometric isomer: true

ChurnClassificationEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Churn Classification
status: DRAFT
subclass of: BinaryClassificationSchemaEnum
union of: RETAINED
union of: CHURNED
definition: Customer churn prediction labels
in scheme: merged
permissible values: CHURNED
permissible values: RETAINED
source domain: data_science
source schema: binary_classification

CHURNED
type: Class
subclass of: ChurnClassificationEnum
alternative label: 1
alternative label: attrited
alternative label: inactive
alternative label: lost
definition: Customer stopped using the service
note: No appropriate ontology term found for customer churn

RETAINED
type: Class
subclass of: ChurnClassificationEnum
alternative label: 0
alternative label: active
alternative label: staying
definition: Customer continues using the service
note: No appropriate ontology term found for customer retention

ACS
type: Class
subclass of: CitationStyle
definition: American Chemical Society

AMA
type: Class
subclass of: CitationStyle
definition: American Medical Association

APA
type: Class
subclass of: CitationStyle
definition: American Psychological Association

CELL
type: Class
subclass of: CitationStyle
definition: Cell Press style

CHICAGO
type: Class
subclass of: CitationStyle
definition: Chicago Manual of Style

HARVARD
type: Class
subclass of: CitationStyle
definition: Harvard referencing

IEEE
type: Class
subclass of: CitationStyle
definition: Institute of Electrical and Electronics Engineers

MLA
type: Class
subclass of: CitationStyle
definition: Modern Language Association

NATURE
type: Class
subclass of: CitationStyle
definition: Nature style

SCIENCE
type: Class
subclass of: CitationStyle
definition: Science style

VANCOUVER
type: Class
subclass of: CitationStyle
definition: Vancouver style (biomedical)

ACTIGRAPHY
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Actigraphy monitoring

ACTIVE_AVOIDANCE
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: active avoidance learning behavior assay
definition: Active avoidance learning behavior assay

ALGOMETRX_NOCIOMETER
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: AlgometRx Nociometer assessment

AUDITORY_BRAINSTEM_RESPONSE
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: ABR
definition: Auditory brainstem response testing

BLOOD_CHEMISTRY
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: blood chemistry measurement
definition: Blood chemistry measurement

CBCL_1_5_5
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Child Behavior Checklist for Ages 1.5-5
definition: Child Behavior Checklist for Ages 1.5-5

CBCL_6_18
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Child Behavior Checklist for Ages 6-18
definition: Child Behavior Checklist for Ages 6-18

CDLQI
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Children's Dermatology Life Quality Index Questionnaire
definition: Children's Dermatology Life Quality Index Questionnaire

CLINICAL_DATA
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Clinical data collection

CNF_SKINDEX
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: cNF-Skindex
definition: Cutaneous neurofibroma Skindex

COGNITIVE_ASSESSMENT
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Cognitive function assessment

CONTEXTUAL_CONDITIONING
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: contextual conditioning behavior assay
definition: Contextual conditioning behavior assay

CORSI_BLOCKS
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Corsi block-tapping task

DPOE
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: distortion product otoacoustic emissions
definition: Distortion product otoacoustic emissions

FACEQ_DISTRESS
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: FACE-Q Appearance-related Distress
definition: FACE-Q Appearance-related Distress

FEEDING_ASSAY
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Feeding behavior assay

FOCUS_GROUP
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Focus group discussion

GAIT_MEASUREMENT
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: gait measurement
definition: Gait analysis measurement

GRIP_STRENGTH
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Grip strength measurement

HAND_HELD_DYNAMOMETRY
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Hand-held dynamometry

INTERVIEW
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Clinical or research interview

METABOLIC_SCREENING
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Metabolic screening panel

NIH_TOOLBOX
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: NIH Toolbox assessment battery

NOVELTY_RESPONSE
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: novelty response behavior assay
definition: Novelty response behavior assay

N_BACK_TASK
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: n-back task
definition: N-back working memory task

OPTOKINETIC_REFLEX
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: optokinetic reflex assay
definition: Optokinetic reflex assay

PATTERN_ERG
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: pattern electroretinogram
definition: Pattern electroretinogram

POLYSOMNOGRAPHY
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Polysomnography sleep study

PROMIS_COGNITIVE_FUNCTION
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: PROMIS Cognitive Function measures

PURE_TONE_AVERAGE
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Pure tone average audiometry

QUANTITATIVE_SENSORY_TESTING
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Quantitative sensory testing

RICCARDI_ABLON_SCALES
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Riccardi and Ablon clinical severity scales

SCALE
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Clinical rating scale

SIX_MINUTE_WALK_TEST
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: six-minute walk test
definition: Six-minute walk test

SKINDEX_16
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Skindex-16 dermatology questionnaire

SRS
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Social Responsiveness Scale
definition: Social Responsiveness Scale

SRS_2
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Social Responsiveness Scale Second Edition
definition: Social Responsiveness Scale Second Edition

VON_FREY_TEST
type: Class
subclass of: ClinicalBehavioralAssayEnum
alternative label: Von Frey test
definition: Von Frey filament test

WORD_RECOGNITION_SCORE
type: Class
subclass of: ClinicalBehavioralAssayEnum
definition: Word recognition score

AAA
type: Class
title: Lysine codon
subclass of: CodonEnum
amino acid: K
amino acid name: Lysine

AAC
type: Class
title: Asparagine codon
subclass of: CodonEnum
amino acid: N
amino acid name: Asparagine

AAG
type: Class
title: Lysine codon
subclass of: CodonEnum
amino acid: K
amino acid name: Lysine

AAT
type: Class
title: Asparagine codon
subclass of: CodonEnum
amino acid: N
amino acid name: Asparagine

ACA
type: Class
title: Threonine codon
subclass of: CodonEnum
amino acid: T
amino acid name: Threonine

ACC
type: Class
title: Threonine codon
subclass of: CodonEnum
amino acid: T
amino acid name: Threonine

ACG
type: Class
title: Threonine codon
subclass of: CodonEnum
amino acid: T
amino acid name: Threonine

ACT
type: Class
title: Threonine codon
subclass of: CodonEnum
amino acid: T
amino acid name: Threonine

AGA
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

AGC
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

AGG
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

AGT
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

ATA
type: Class
title: Isoleucine codon
subclass of: CodonEnum
amino acid: I
amino acid name: Isoleucine

ATC
type: Class
title: Isoleucine codon
subclass of: CodonEnum
amino acid: I
amino acid name: Isoleucine

ATG
type: Class
title: Methionine codon (start codon)
subclass of: CodonEnum
amino acid: M
amino acid name: Methionine
special: start codon

ATT
type: Class
title: Isoleucine codon
subclass of: CodonEnum
amino acid: I
amino acid name: Isoleucine

CAA
type: Class
title: Glutamine codon
subclass of: CodonEnum
amino acid: Q
amino acid name: Glutamine

CAC
type: Class
title: Histidine codon
subclass of: CodonEnum
amino acid: H
amino acid name: Histidine

CAG
type: Class
title: Glutamine codon
subclass of: CodonEnum
amino acid: Q
amino acid name: Glutamine

CAT
type: Class
title: Histidine codon
subclass of: CodonEnum
amino acid: H
amino acid name: Histidine

CCA
type: Class
title: Proline codon
subclass of: CodonEnum
amino acid: P
amino acid name: Proline

CCC
type: Class
title: Proline codon
subclass of: CodonEnum
amino acid: P
amino acid name: Proline

CCG
type: Class
title: Proline codon
subclass of: CodonEnum
amino acid: P
amino acid name: Proline

CCT
type: Class
title: Proline codon
subclass of: CodonEnum
amino acid: P
amino acid name: Proline

CGA
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

CGC
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

CGG
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

CGT
type: Class
title: Arginine codon
subclass of: CodonEnum
amino acid: R
amino acid name: Arginine

CTA
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

CTC
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

CTG
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

CTT
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

GAA
type: Class
title: Glutamic acid codon
subclass of: CodonEnum
amino acid: E
amino acid name: Glutamic acid

GAC
type: Class
title: Aspartic acid codon
subclass of: CodonEnum
amino acid: D
amino acid name: Aspartic acid

GAG
type: Class
title: Glutamic acid codon
subclass of: CodonEnum
amino acid: E
amino acid name: Glutamic acid

GAT
type: Class
title: Aspartic acid codon
subclass of: CodonEnum
amino acid: D
amino acid name: Aspartic acid

GCA
type: Class
title: Alanine codon
subclass of: CodonEnum
amino acid: A
amino acid name: Alanine

GCC
type: Class
title: Alanine codon
subclass of: CodonEnum
amino acid: A
amino acid name: Alanine

GCG
type: Class
title: Alanine codon
subclass of: CodonEnum
amino acid: A
amino acid name: Alanine

GCT
type: Class
title: Alanine codon
subclass of: CodonEnum
amino acid: A
amino acid name: Alanine

GGA
type: Class
title: Glycine codon
subclass of: CodonEnum
amino acid: G
amino acid name: Glycine

GGC
type: Class
title: Glycine codon
subclass of: CodonEnum
amino acid: G
amino acid name: Glycine

GGG
type: Class
title: Glycine codon
subclass of: CodonEnum
amino acid: G
amino acid name: Glycine

GGT
type: Class
title: Glycine codon
subclass of: CodonEnum
amino acid: G
amino acid name: Glycine

GTA
type: Class
title: Valine codon
subclass of: CodonEnum
amino acid: V
amino acid name: Valine

GTC
type: Class
title: Valine codon
subclass of: CodonEnum
amino acid: V
amino acid name: Valine

GTG
type: Class
title: Valine codon
subclass of: CodonEnum
amino acid: V
amino acid name: Valine

GTT
type: Class
title: Valine codon
subclass of: CodonEnum
amino acid: V
amino acid name: Valine

TAA
type: Class
title: Stop codon (ochre)
subclass of: CodonEnum
amino acid: *
name: ochre
special: stop codon

TAC
type: Class
title: Tyrosine codon
subclass of: CodonEnum
amino acid: Y
amino acid name: Tyrosine

TAG
type: Class
title: Stop codon (amber)
subclass of: CodonEnum
amino acid: *
name: amber
special: stop codon

TAT
type: Class
title: Tyrosine codon
subclass of: CodonEnum
amino acid: Y
amino acid name: Tyrosine

TCA
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

TCC
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

TCG
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

TCT
type: Class
title: Serine codon
subclass of: CodonEnum
amino acid: S
amino acid name: Serine

TGA
type: Class
title: Stop codon (opal/umber)
subclass of: CodonEnum
amino acid: *
name: opal
special: stop codon or selenocysteine

TGC
type: Class
title: Cysteine codon
subclass of: CodonEnum
amino acid: C
amino acid name: Cysteine

TGG
type: Class
title: Tryptophan codon
subclass of: CodonEnum
amino acid: W
amino acid name: Tryptophan

TGT
type: Class
title: Cysteine codon
subclass of: CodonEnum
amino acid: C
amino acid name: Cysteine

TTA
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

TTC
type: Class
title: Phenylalanine codon
subclass of: CodonEnum
amino acid: F
amino acid name: Phenylalanine

TTG
type: Class
title: Leucine codon
subclass of: CodonEnum
amino acid: L
amino acid name: Leucine

TTT
type: Class
title: Phenylalanine codon
subclass of: CodonEnum
amino acid: F
amino acid name: Phenylalanine

CMYK
type: Class
subclass of: ColorSpaceEnum
definition: Cyan Magenta Yellow Key (black) color model

HSL
type: Class
subclass of: ColorSpaceEnum
definition: Hue Saturation Lightness color model

HSV
type: Class
subclass of: ColorSpaceEnum
definition: Hue Saturation Value color model

LAB
type: Class
subclass of: ColorSpaceEnum
definition: CIELAB color space

MUNSELL
type: Class
subclass of: ColorSpaceEnum
definition: Munsell color system

NCS
type: Class
subclass of: ColorSpaceEnum
definition: Natural Color System

PANTONE
type: Class
subclass of: ColorSpaceEnum
definition: Pantone Matching System

RAL
type: Class
subclass of: ColorSpaceEnum
definition: RAL color standard

RGB
type: Class
subclass of: ColorSpaceEnum
definition: Red Green Blue color model

CUSTOM_API
type: Class
title: custom API
subclass of: CommunicationProtocolEnum
definition: Vendor-specific custom API

GRPC
type: Class
title: gRPC
subclass of: CommunicationProtocolEnum
definition: gRPC protocol used in SiLA 2
used by: SiLA 2

MODBUS
type: Class
title: Modbus
subclass of: CommunicationProtocolEnum
definition: Serial communication protocol for industrial devices

OPC_UA
type: Class
title: OPC UA
subclass of: CommunicationProtocolEnum
definition: OPC Unified Architecture for industrial automation
full name: OPC Unified Architecture

REST_API
type: Class
title: REST API
subclass of: CommunicationProtocolEnum
definition: RESTful HTTP-based API

SERIAL
type: Class
title: serial
subclass of: CommunicationProtocolEnum
definition: Serial communication protocol (RS-232, RS-485)

SOAP
type: Class
subclass of: CommunicationProtocolEnum
definition: Simple Object Access Protocol

TCP_IP
type: Class
title: TCP/IP
subclass of: CommunicationProtocolEnum
definition: TCP/IP network protocol

USB
type: Class
subclass of: CommunicationProtocolEnum
definition: Universal Serial Bus communication

EAST
type: Class
subclass of: CompassDirection
definition: East (90°)
abbreviation: E
degrees: 90

EAST_NORTHEAST
type: Class
subclass of: CompassDirection
definition: East-northeast (67.5°)
abbreviation: ENE
degrees: 6.75e+01

EAST_SOUTHEAST
type: Class
subclass of: CompassDirection
definition: East-southeast (112.5°)
abbreviation: ESE
degrees: 1.125e+02

NORTH
type: Class
subclass of: CompassDirection
definition: North (0°/360°)
abbreviation: N
degrees: 0

NORTHEAST
type: Class
subclass of: CompassDirection
definition: Northeast (45°)
abbreviation: NE
degrees: 45

NORTHWEST
type: Class
subclass of: CompassDirection
definition: Northwest (315°)
abbreviation: NW
degrees: 315

NORTH_NORTHEAST
type: Class
subclass of: CompassDirection
definition: North-northeast (22.5°)
abbreviation: NNE
degrees: 2.25e+01

NORTH_NORTHWEST
type: Class
subclass of: CompassDirection
definition: North-northwest (337.5°)
abbreviation: NNW
degrees: 3.375e+02

SOUTH
type: Class
subclass of: CompassDirection
definition: South (180°)
abbreviation: S
degrees: 180

SOUTHEAST
type: Class
subclass of: CompassDirection
definition: Southeast (135°)
abbreviation: SE
degrees: 135

SOUTHWEST
type: Class
subclass of: CompassDirection
definition: Southwest (225°)
abbreviation: SW
degrees: 225

SOUTH_SOUTHEAST
type: Class
subclass of: CompassDirection
definition: South-southeast (157.5°)
abbreviation: SSE
degrees: 1.575e+02

SOUTH_SOUTHWEST
type: Class
subclass of: CompassDirection
definition: South-southwest (202.5°)
abbreviation: SSW
degrees: 2.025e+02

WEST
type: Class
subclass of: CompassDirection
definition: West (270°)
abbreviation: W
degrees: 270

WEST_NORTHWEST
type: Class
subclass of: CompassDirection
definition: West-northwest (292.5°)
abbreviation: WNW
degrees: 2.925e+02

WEST_SOUTHWEST
type: Class
subclass of: CompassDirection
definition: West-southwest (247.5°)
abbreviation: WSW
degrees: 2.475e+02

BASE_SALARY
type: Class
title: Base Salary
subclass of: CompensationTypeEnum
definition: Fixed annual salary compensation
exemption: often exempt from overtime
market: market benchmarked
payment: regular pay periods
predictability: predictable income
structure: fixed annual amount

BONUS
type: Class
title: Performance Bonus
subclass of: CompensationTypeEnum
definition: Additional compensation for performance
criteria: performance criteria
discretionary: may be discretionary
recognition: performance recognition
retention: retention tool
timing: annual or periodic

COMMISSION
type: Class
title: Commission
subclass of: CompensationTypeEnum
definition: Performance-based sales commission
motivation: sales motivation
performance: performance-based
risk: income risk
structure: percentage of sales
variability: highly variable

HOURLY_WAGE
type: Class
title: Hourly Wage
subclass of: CompensationTypeEnum
definition: Compensation paid per hour worked
classification: non-exempt employees
overtime: overtime eligible
structure: rate per hour
tracking: time tracking required
variability: variable based on hours

PIECE_RATE
type: Class
title: Piece Rate
subclass of: CompensationTypeEnum
definition: Compensation based on units produced
efficiency: efficiency incentive
manufacturing: common in manufacturing
measurement: output measurement
productivity: productivity-based
structure: rate per unit produced

PROFIT_SHARING
type: Class
title: Profit Sharing
subclass of: CompensationTypeEnum
definition: Sharing of company profits with employees
alignment: interest alignment
culture: ownership culture
performance: company performance based
structure: percentage of profits
variability: variable based on profits

STIPEND
type: Class
title: Stipend
subclass of: CompensationTypeEnum
definition: Fixed regular allowance or payment
amount: modest fixed amount
categories: interns, volunteers, board members
purpose: specific purpose payment
regularity: regular payment
supplemental: supplemental income

STOCK_OPTIONS
type: Class
title: Stock Options
subclass of: CompensationTypeEnum
definition: Equity compensation through stock options
equity: equity participation
retention: long-term retention
risk: market risk
upside: company growth upside
vesting: vesting schedule

ANSI_N45_2
type: Class
title: ANSI N45.2 Quality Assurance
subclass of: ComplianceStandardEnum
definition: Quality Assurance Program Requirements for Nuclear Power Plants

ASME_NQA_1
type: Class
title: ASME NQA-1 Quality Assurance
subclass of: ComplianceStandardEnum
definition: Quality Assurance Requirements for Nuclear Facility Applications

IAEA_GSR
type: Class
title: IAEA General Safety Requirements
subclass of: ComplianceStandardEnum
definition: IAEA General Safety Requirements

IAEA_NSS
type: Class
title: IAEA Nuclear Security Series
subclass of: ComplianceStandardEnum
definition: IAEA Nuclear Security Series

IEC_61513
type: Class
title: IEC 61513 I&C Systems
subclass of: ComplianceStandardEnum
definition: Nuclear power plants - Instrumentation and control systems

IEEE_603
type: Class
title: IEEE 603 Safety Systems Criteria
subclass of: ComplianceStandardEnum
definition: IEEE Standard Criteria for Safety Systems for Nuclear Power Generating Stations

ISO_14001
type: Class
title: ISO 14001 Environmental Management
subclass of: ComplianceStandardEnum
definition: Environmental Management Systems

ISO_9001
type: Class
title: ISO 9001 Quality Management
subclass of: ComplianceStandardEnum
definition: Quality Management Systems

NUREG_0800
type: Class
title: NUREG-0800 Standard Review Plan
subclass of: ComplianceStandardEnum
definition: Standard Review Plan for the Review of Safety Analysis Reports

WENRA_RL
type: Class
title: WENRA Reference Levels
subclass of: ComplianceStandardEnum
definition: Western European Nuclear Regulators Association Reference Levels

CERAMIC_MATRIX_COMPOSITE
type: Class
title: Ceramic Matrix Composite
subclass of: CompositeTypeEnum
alternative label: CMC
definition: Composite with ceramic matrix

FIBER_REINFORCED
type: Class
title: Fiber-Reinforced Composite
subclass of: CompositeTypeEnum
alternative label: FRC
definition: Composite with fiber reinforcement

LAMINAR_COMPOSITE
type: Class
title: Laminar Composite
subclass of: CompositeTypeEnum
alternative label: laminate
definition: Composite with layered structure

METAL_MATRIX_COMPOSITE
type: Class
title: Metal Matrix Composite
subclass of: CompositeTypeEnum
alternative label: MMC
definition: Composite with metal matrix

PARTICLE_REINFORCED
type: Class
title: Particle-Reinforced Composite
subclass of: CompositeTypeEnum
definition: Composite with particle reinforcement

POLYMER_MATRIX_COMPOSITE
type: Class
title: Polymer Matrix Composite
subclass of: CompositeTypeEnum
alternative label: PMC
definition: Composite with polymer matrix

TAR_GZ
type: Class
subclass of: CompressionFormat
definition: TAR archive compressed with GZIP
mime type: application/gzip
typical extension: .tar.gz

BR
type: Class
subclass of: CompressionType
definition: Brotli compression

COMPRESS
type: Class
subclass of: CompressionType
definition: Unix compress

DEFLATE
type: Class
subclass of: CompressionType
definition: DEFLATE compression

GZIP
type: Class
subclass of: CompressionType
definition: GZIP compression

IDENTITY
type: Class
subclass of: CompressionType
definition: No compression

ComputationalMaterialsSchemaEnum
type: Class
subclass of: MaterialsScienceDomainEnum
definition: Schema-level enum for computational_materials in materials_science
in scheme: merged
source file: materials_science/computational_materials.yaml

CLINICAL_DIAGNOSIS
type: Class
subclass of: ConditionProvenanceEnum
definition: Clinically confirmed diagnosis

EHR_BILLING_DIAGNOSIS
type: Class
subclass of: ConditionProvenanceEnum
definition: Diagnosis recorded for billing purposes in EHR

EHR_CHIEF_COMPLAINT
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition documented as chief complaint in EHR

EHR_ENCOUNTER_DIAGNOSIS
type: Class
subclass of: ConditionProvenanceEnum
definition: Diagnosis recorded during healthcare encounter

EHR_EPISODE_ENTRY
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition recorded as part of care episode

EHR_PROBLEM_LIST_ENTRY
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition on patient problem list in EHR

FIRST_POSITION_CONDITION
type: Class
subclass of: ConditionProvenanceEnum
definition: Primary diagnosis in first position on claim

NLP_DERIVED
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition derived through natural language processing

OBSERVATION_RECORDED_FROM_EHR
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition recorded as observation in EHR

PATIENT_SELF_REPORTED_CONDITION
type: Class
subclass of: ConditionProvenanceEnum
alternative label: PATIENT_SELF-REPORTED_CONDITION
definition: Condition reported by the patient

PRIMARY_CONDITION
type: Class
subclass of: ConditionProvenanceEnum
definition: Primary condition for an encounter or episode

REFERRAL_RECORD
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition documented in referral record

SECONDARY_CONDITION
type: Class
subclass of: ConditionProvenanceEnum
definition: Secondary or comorbid condition

TUMOR_REGISTRY
type: Class
subclass of: ConditionProvenanceEnum
definition: Condition from tumor registry

WORKING_DIAGNOSIS
type: Class
subclass of: ConditionProvenanceEnum
definition: Preliminary or working diagnosis

HIGH
type: Class
title: High
subclass of: ConfidenceLevelEnum
alternative label: 4
alternative label: confident
definition: High confidence (80-95%)

LOW
type: Class
title: Low
subclass of: ConfidenceLevelEnum
alternative label: 2
alternative label: uncertain
definition: Low confidence (40-60%)

MEDIUM
type: Class
title: Medium
subclass of: ConfidenceLevelEnum
alternative label: 3
alternative label: moderate
definition: Medium confidence (60-80%)

VERY_HIGH
type: Class
title: Very High
subclass of: ConfidenceLevelEnum
alternative label: 5
alternative label: certain
definition: Very high confidence (>95%)

VERY_LOW
type: Class
title: Very Low
subclass of: ConfidenceLevelEnum
alternative label: 1
alternative label: guess
definition: Very low confidence (<40%)

INTACT_CONFIDENCE
type: Class
subclass of: ConfidenceScore
definition: IntAct curation confidence

INTACT_MISCORE
type: Class
subclass of: ConfidenceScore
definition: IntAct molecular interaction score

MATRIXDB_SCORE
type: Class
subclass of: ConfidenceScore
definition: MatrixDB confidence score

MINT_SCORE
type: Class
subclass of: ConfidenceScore
definition: MINT database score

ConstructionSchemaEnum
type: Class
subclass of: IndustryDomainEnum
definition: Schema-level enum for construction in industry
in scheme: merged
source file: industry/construction.yaml

DEEP_WELL_PLATE
type: Class
title: deep well plate
subclass of: ContainerTypeEnum
definition: A microplate with deeper wells for increased sample volume capacity

MICROTUBE
type: Class
title: microtube
subclass of: ContainerTypeEnum
definition: Small laboratory tube with volume capacity from 0.2 ml to 2.0 ml
volume range: 0.2-2.0 ml

PCR_PLATE
type: Class
title: PCR plate
subclass of: ContainerTypeEnum
definition: A microplate specifically designed for PCR thermal cycling applications

PIPETTE_TIP_BOX
type: Class
title: pipette tip box
subclass of: ContainerTypeEnum
definition: Container for storing pipette tips in organized racks

RESERVOIR
type: Class
title: reservoir
subclass of: ContainerTypeEnum
definition: Container for holding bulk reagents for dispensing

SCREW_CAP_TUBE
type: Class
title: screw cap tube
subclass of: ContainerTypeEnum
definition: Laboratory tube with screw cap closure

SNAP_CAP_TUBE
type: Class
title: snap cap tube
subclass of: ContainerTypeEnum
definition: Laboratory tube with snap cap closure

TUBE_RACK
type: Class
title: tube rack
subclass of: ContainerTypeEnum
definition: A rack designed to hold multiple laboratory tubes

ISOLATE
type: Class
subclass of: ContigCollectionType
definition: Sequences assembled from DNA of isolated organism. Bacteria/Archaea: https://genomicsstandardsconsortium.github.io/mixs/0010003/ Euk: https://genomicsstandardsconsortium.github.io/mixs/0010002/ Virus: https://genomicsstandardsconsortium.github.io/mixs/0010005/ Organelle: https://genomicsstandardsconsortium.github.io/mixs/0010006/ Plasmid: https://genomicsstandardsconsortium.github.io/mixs/0010004/

MARKER
type: Class
subclass of: ContigCollectionType
definition: Sequences from targeted region of DNA; see protocol for information on targeted region. specimen: https://genomicsstandardsconsortium.github.io/mixs/0010009/ survey: https://genomicsstandardsconsortium.github.io/mixs/0010008/

METATRANSCRIPTOME
type: Class
subclass of: ContigCollectionType
definition: Sequences assembled from RNA of mixed community. Currently not represented by GSC.

AFRICA
type: Class
subclass of: ContinentEnum
definition: Africa

ANTARCTICA
type: Class
subclass of: ContinentEnum
definition: Antarctica

ASIA
type: Class
subclass of: ContinentEnum
definition: Asia

EUROPE
type: Class
subclass of: ContinentEnum
definition: Europe

NORTH_AMERICA
type: Class
subclass of: ContinentEnum
definition: North America

OCEANIA
type: Class
subclass of: ContinentEnum
definition: Oceania (including Australia)

SOUTH_AMERICA
type: Class
subclass of: ContinentEnum
definition: South America

ContributorType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Contributor Type
status: DRAFT
subclass of: ContributorSchemaEnum
union of: PERSON
union of: ORGANIZATION
definition: The type of contributor being represented.
in scheme: merged
permissible values: PERSON
permissible values: ORGANIZATION
source domain: root
source schema: contributor

BENT
type: Class
subclass of: CoordinationGeometry
definition: Bent or angular coordination geometry
coordination number: 2

CUBIC
type: Class
subclass of: CoordinationGeometry
definition: Cubic coordination geometry (8 ligands)
coordination number: 8

DODECAHEDRAL
type: Class
subclass of: CoordinationGeometry
definition: Dodecahedral coordination geometry (8 ligands)
coordination number: 8

HEXAGONAL_BIPYRAMIDAL
type: Class
subclass of: CoordinationGeometry
definition: Hexagonal bipyramidal coordination geometry (8 ligands)
coordination number: 8

LINEAR
type: Class
subclass of: CoordinationGeometry
definition: Linear coordination geometry (2 ligands at 180°)
coordination number: 2

PENTAGONAL_BIPYRAMIDAL
type: Class
subclass of: CoordinationGeometry
definition: Pentagonal bipyramidal coordination geometry (7 ligands)
coordination number: 7

PENTAGONAL_PLANAR
type: Class
subclass of: CoordinationGeometry
definition: Pentagonal planar coordination geometry (5 ligands in plane)
coordination number: 5

SEE_SAW
type: Class
subclass of: CoordinationGeometry
definition: See-saw coordination geometry (4 ligands)
coordination number: 4

SQUARE_ANTIPRISMATIC
type: Class
subclass of: CoordinationGeometry
definition: Square antiprismatic coordination geometry (8 ligands)
coordination number: 8

SQUARE_PYRAMIDAL
type: Class
subclass of: CoordinationGeometry
definition: Square pyramidal coordination geometry (5 ligands)
coordination number: 5

TRIGONAL_BIPYRAMIDAL
type: Class
subclass of: CoordinationGeometry
definition: Trigonal bipyramidal coordination geometry (5 ligands)
coordination number: 5

TRIGONAL_PLANAR
type: Class
subclass of: CoordinationGeometry
definition: Trigonal planar coordination geometry (3 ligands, 120° angles)
coordination number: 3

TRIGONAL_PRISMATIC
type: Class
subclass of: CoordinationGeometry
definition: Trigonal prismatic coordination geometry (6 ligands)
coordination number: 6

TRIGONAL_PYRAMIDAL
type: Class
subclass of: CoordinationGeometry
definition: Trigonal pyramidal coordination geometry
coordination number: 3

T_SHAPED
type: Class
subclass of: CoordinationGeometry
definition: T-shaped coordination geometry
coordination number: 3

CoreSchemaEnum
type: Class
subclass of: RootDomainEnum
definition: Schema-level enum for core in root
in scheme: merged
source file: core.yaml

AUDIT_COMMITTEE_CHAIR
type: Class
title: Audit Committee Chair
subclass of: CorporateGovernanceRoleEnum
definition: Chair of board's audit committee
committee: audit committee leadership
expertise: financial expertise required
independence: must be independent
oversight: financial oversight

CHAIRMAN_OF_BOARD
type: Class
title: Chairman of the Board
subclass of: CorporateGovernanceRoleEnum
definition: Leader of board of directors
governance: governance oversight
interface: shareholder interface
leadership: board leadership
meetings: chairs board meetings

CHIEF_EXECUTIVE_OFFICER
type: Class
title: Chief Executive Officer (CEO)
subclass of: CorporateGovernanceRoleEnum
definition: Highest-ranking executive officer
accountability: accountable to board
authority: highest executive authority
representation: company representation
strategy: strategic leadership

CHIEF_FINANCIAL_OFFICER
type: Class
title: Chief Financial Officer (CFO)
subclass of: CorporateGovernanceRoleEnum
definition: Senior executive responsible for financial management
compliance: financial compliance
reporting: financial reporting oversight
responsibility: financial management
strategy: financial strategy

CHIEF_OPERATING_OFFICER
type: Class
title: Chief Operating Officer (COO)
subclass of: CorporateGovernanceRoleEnum
definition: Senior executive responsible for operations
coordination: cross-functional coordination
efficiency: operational efficiency
execution: strategy execution
responsibility: operational management

COMPENSATION_COMMITTEE_CHAIR
type: Class
title: Compensation Committee Chair
subclass of: CorporateGovernanceRoleEnum
definition: Chair of board's compensation committee
alignment: shareholder interest alignment
committee: compensation committee leadership
independence: must be independent
responsibility: executive compensation oversight

CORPORATE_SECRETARY
type: Class
title: Corporate Secretary
subclass of: CorporateGovernanceRoleEnum
definition: Officer responsible for corporate records and governance compliance
compliance: governance compliance
legal: legal compliance oversight
meetings: board meeting coordination
records: corporate records maintenance

INDEPENDENT_DIRECTOR
type: Class
title: Independent Director
subclass of: CorporateGovernanceRoleEnum
definition: Board member independent from company management
committees: serves on key committees
governance: independent governance perspective
independence: independent from management
objectivity: objective oversight

INSIDE_DIRECTOR
type: Class
title: Inside Director
subclass of: CorporateGovernanceRoleEnum
definition: Board member who is also company employee or has material relationship
expertise: insider knowledge
perspective: management perspective
potential conflicts: potential conflicts of interest
relationship: material relationship with company

LEAD_INDEPENDENT_DIRECTOR
type: Class
title: Lead Independent Director
subclass of: CorporateGovernanceRoleEnum
definition: Senior independent director when chairman is not independent
communication: shareholder communication
independence: independent from management
leadership: leads independent directors
oversight: additional oversight role

NOMINATING_COMMITTEE_CHAIR
type: Class
title: Nominating Committee Chair
subclass of: CorporateGovernanceRoleEnum
definition: Chair of board's nominating and governance committee
committee: nominating committee leadership
governance: governance best practices
responsibility: board composition and governance
succession: leadership succession planning

C_FLAT
type: Class
subclass of: CryoEMGridType
definition: C-flat holey carbon grid
hole sizes: 1.2/1.3, 2/1, 2/2 μm common
manufacturer: Protochips

GOLD_GRID
type: Class
subclass of: CryoEMGridType
definition: Pure gold grid
advantages: inert, high-resolution imaging

GRAPHENE_OXIDE
type: Class
subclass of: CryoEMGridType
definition: Graphene oxide support
advantages: atomically thin, good contrast

LACEY_CARBON
type: Class
subclass of: CryoEMGridType
definition: Lacey carbon support film
structure: irregular holes, thin carbon film

QUANTIFOIL
type: Class
subclass of: CryoEMGridType
definition: Quantifoil holey carbon grid
hole sizes: 1.2/1.3, 2/1, 2/2 μm common
manufacturer: Quantifoil

ULTRATHIN_CARBON
type: Class
subclass of: CryoEMGridType
definition: Ultrathin carbon film on holey support
thickness: 3-5 nm typical

CRYO_SECTIONING
type: Class
subclass of: CryoEMPreparationType
definition: Cryo-sectioned sample

FREEZE_SUBSTITUTION
type: Class
subclass of: CryoEMPreparationType
definition: Freeze-substituted sample

HIGH_PRESSURE_FREEZING
type: Class
subclass of: CryoEMPreparationType
definition: High-pressure frozen sample

VITREOUS_ICE
type: Class
subclass of: CryoEMPreparationType
definition: Sample embedded in vitreous ice

BLAKE2B_256
type: Class
title: BLAKE2b-256
subclass of: CryptographicHashFunction
definition: BLAKE2b variant producing a 256-bit hash value. Faster than MD5 and SHA-1 while being more secure.
output bits: 256
security level: secure

BLAKE2B_384
type: Class
title: BLAKE2b-384
subclass of: CryptographicHashFunction
definition: BLAKE2b variant producing a 384-bit hash value.
output bits: 384
security level: secure

BLAKE2B_512
type: Class
title: BLAKE2b-512
subclass of: CryptographicHashFunction
definition: BLAKE2b variant producing a 512-bit hash value. Optimized for 64-bit platforms.
output bits: 512
security level: secure

BLAKE3
type: Class
subclass of: CryptographicHashFunction
definition: Latest BLAKE variant, extremely fast with 256-bit output. Supports parallelization and incremental hashing.
output bits: 256
security level: secure

MD4
type: Class
subclass of: CryptographicHashFunction
definition: Message Digest 4 algorithm producing a 128-bit hash value. Predecessor to MD5. Considered cryptographically broken.
output bits: 128
security level: broken

MD6
type: Class
subclass of: CryptographicHashFunction
definition: Message Digest 6 algorithm with variable output size. Designed as a candidate for SHA-3 but not selected.
output bits: variable
security level: adequate

SHA3_224
type: Class
title: SHA3-224
subclass of: CryptographicHashFunction
definition: SHA-3 variant producing a 224-bit hash value. Based on the Keccak algorithm.
output bits: 224
security level: secure

SHA3_256
type: Class
title: SHA3-256
subclass of: CryptographicHashFunction
definition: SHA-3 variant producing a 256-bit hash value. Based on the Keccak algorithm. Provides defense against length extension attacks.
output bits: 256
security level: secure

SHA3_384
type: Class
title: SHA3-384
subclass of: CryptographicHashFunction
definition: SHA-3 variant producing a 384-bit hash value. Based on the Keccak algorithm.
output bits: 384
security level: secure

SHA3_512
type: Class
title: SHA3-512
subclass of: CryptographicHashFunction
definition: SHA-3 variant producing a 512-bit hash value. Based on the Keccak algorithm.
output bits: 512
security level: secure

SHA_224
type: Class
title: SHA-224
subclass of: CryptographicHashFunction
alternative label: SHA224
definition: SHA-2 variant producing a 224-bit hash value. Truncated version of SHA-256.
output bits: 224
security level: secure

BRIDGMAN
type: Class
title: Bridgman Method
subclass of: CrystalGrowthMethodEnum
alternative label: Bridgman-Stockbarger
definition: Directional solidification method

CZOCHRALSKI
type: Class
title: Czochralski Method
subclass of: CrystalGrowthMethodEnum
alternative label: CZ
alternative label: crystal pulling
definition: Crystal pulling from melt

FLOAT_ZONE
type: Class
title: Float Zone
subclass of: CrystalGrowthMethodEnum
alternative label: FZ
alternative label: zone refining
definition: Zone melting without crucible

FLUX_GROWTH
type: Class
title: Flux Growth
subclass of: CrystalGrowthMethodEnum
definition: Crystal growth from high temperature solution

HYDROTHERMAL_GROWTH
type: Class
title: Hydrothermal Growth
subclass of: CrystalGrowthMethodEnum
definition: Crystal growth in aqueous solution under pressure

LPE
type: Class
subclass of: CrystalGrowthMethodEnum
alternative label: Liquid Phase Epitaxy
definition: Liquid Phase Epitaxy

MOCVD
type: Class
subclass of: CrystalGrowthMethodEnum
alternative label: MOVPE
definition: Metal-Organic Chemical Vapor Deposition

VAPOR_TRANSPORT
type: Class
title: Vapor Transport
subclass of: CrystalGrowthMethodEnum
alternative label: CVT
definition: Crystal growth via vapor phase transport

CrystalStructuresSchemaEnum
type: Class
subclass of: MaterialsScienceDomainEnum
definition: Schema-level enum for crystal_structures in materials_science
in scheme: merged
source file: materials_science/crystal_structures.yaml

DIALYSIS
type: Class
subclass of: CrystallizationMethod
definition: Dialysis crystallization
applications: large volume samples, gentle conditions

FREE_INTERFACE_DIFFUSION
type: Class
subclass of: CrystallizationMethod
definition: Free interface diffusion
setup: capillary tubes, gel interface

LCP
type: Class
subclass of: CrystallizationMethod
definition: Lipidic cubic phase crystallization
applications: membrane proteins
lipid: monoolein most common

MICROBATCH
type: Class
subclass of: CrystallizationMethod
definition: Microbatch under oil method
advantages: prevents evaporation
oil type: paraffin, silicone oil

VAPOR_DIFFUSION_HANGING
type: Class
subclass of: CrystallizationMethod
definition: Vapor diffusion hanging drop method
advantages: visual monitoring, easy optimization
volume: 2-10 μL drops typical

VAPOR_DIFFUSION_SITTING
type: Class
subclass of: CrystallizationMethod
definition: Vapor diffusion sitting drop method
advantages: automated setup, stable drops

AED
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: UAE Dirham

AUD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Australian Dollar

BRL
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Brazilian Real

CAD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Canadian Dollar

CHF
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Swiss Franc

CNY
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Chinese Yuan Renminbi

DKK
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Danish Krone

EGP
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Egyptian Pound

EUR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Euro

GBP
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: British Pound Sterling

HKD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Hong Kong Dollar

IDR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Indonesian Rupiah

ILS
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Israeli Shekel

INR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Indian Rupee

JPY
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Japanese Yen

KRW
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: South Korean Won

MXN
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Mexican Peso

MYR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Malaysian Ringgit

NOK
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Norwegian Krone

NZD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: New Zealand Dollar

PHP
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Philippine Peso

PLN
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Polish Zloty

RUB
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Russian Ruble

SAR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Saudi Riyal

SEK
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Swedish Krona

SGD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Singapore Dollar

THB
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Thai Baht

TRY
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Turkish Lira

TWD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Taiwan Dollar

USD
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: United States Dollar

VND
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: Vietnamese Dong

ZAR
type: Class
subclass of: CurrencyCodeISO4217Enum
definition: South African Rand

B
type: Class
title: Not A (C, G, or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: C,G,T

D
type: Class
title: Not C (A, G, or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,G,T

GAP
type: Class
title: Gap character
subclass of: DNABaseExtendedEnum
represents: gap
symbol: -

H
type: Class
title: Not G (A, C, or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,C,T

K
type: Class
title: Keto (G or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: G,T

M
type: Class
title: Amino (A or C)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,C

N
type: Class
title: Any nucleotide (A, C, G, or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,C,G,T

R
type: Class
title: Purine (A or G)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,G

S
type: Class
title: Strong (G or C)
subclass of: DNABaseExtendedEnum
bond strength: strong (3 H-bonds)
iupac: true
represents: G,C

V
type: Class
title: Not T (A, C, or G)
subclass of: DNABaseExtendedEnum
iupac: true
represents: A,C,G

W
type: Class
title: Weak (A or T)
subclass of: DNABaseExtendedEnum
bond strength: weak (2 H-bonds)
iupac: true
represents: A,T

Y
type: Class
title: Pyrimidine (C or T)
subclass of: DNABaseExtendedEnum
iupac: true
represents: C,T

CHECKPOINT_ADAPTATION
type: Class
subclass of: DNADamageResponse
definition: Checkpoint adaptation
description: override of checkpoint despite damage

AIR_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Traditional air-based cooling using computer room air conditioning (CRAC) or air handling units

DIRECT_TO_CHIP_LIQUID_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Liquid cooling with cold plates attached directly to processors and other heat-generating components

EVAPORATIVE_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Cooling that uses water evaporation to reduce air temperature
related match: Cooling Tower

FREE_AIR_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Cooling using outside ambient air when conditions permit, reducing mechanical cooling load

GEOTHERMAL_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Cooling that leverages underground temperature stability for heat dissipation

IMMERSION_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Cooling by submerging server hardware in a thermally conductive dielectric liquid

LIQUID_COOLING
type: Class
subclass of: DataCenterCoolingType
definition: Cooling using liquid coolant circulated through heat exchangers near server components

REAR_DOOR_HEAT_EXCHANGER
type: Class
subclass of: DataCenterCoolingType
broad match: Heat Exchanger
definition: Liquid-to-air heat exchanger mounted on the rear door of server racks

TIER_I
type: Class
subclass of: DataCenterTierLevel
definition: Basic capacity - single non-redundant distribution path with no redundancy
classification: Basic
uptime guarantee: 99.671%

TIER_II
type: Class
subclass of: DataCenterTierLevel
definition: Redundant capacity components - single non-redundant distribution path with redundant components
classification: Redundant Components
uptime guarantee: 99.741%

TIER_III
type: Class
subclass of: DataCenterTierLevel
definition: Concurrently maintainable - multiple independent distribution paths with redundant components
classification: Concurrently Maintainable
uptime guarantee: 99.982%

TIER_IV
type: Class
subclass of: DataCenterTierLevel
definition: Fault tolerant - multiple independent distribution paths with redundant components, fault tolerant
classification: Fault Tolerant
uptime guarantee: 99.995%

DataCentersSchemaEnum
type: Class
subclass of: ComputingDomainEnum
definition: Schema-level enum for data_centers in computing
in scheme: merged
source file: computing/data_centers.yaml

DataDomainEnum
type: Class
subclass of: ValueSetEnum
definition: Domain-level enum for data value sets
in scheme: merged

AVRO
type: Class
subclass of: DataFormatEnum
definition: Apache Avro data serialization
extension: .avro
features: schema evolution
mime type: application/avro

ODS
type: Class
subclass of: DataFormatEnum
definition: OpenDocument Spreadsheet
extension: .ods
mime type: application/vnd.oasis.opendocument.spreadsheet

PARQUET
type: Class
subclass of: DataFormatEnum
definition: Apache Parquet columnar format
extension: .parquet
mime type: application/parquet
type: columnar storage

SQLITE
type: Class
subclass of: DataFormatEnum
definition: SQLite database
extension: .db, .sqlite, .sqlite3
mime type: application/x-sqlite3
type: embedded database

TOML
type: Class
subclass of: DataFormatEnum
definition: Tom's Obvious Minimal Language
extension: .toml
mime type: application/toml
use: configuration files

XLS
type: Class
subclass of: DataFormatEnum
definition: Microsoft Excel legacy format
extension: .xls
mime type: application/vnd.ms-excel

XLSX
type: Class
subclass of: DataFormatEnum
definition: Microsoft Excel Open XML
extension: .xlsx
mime type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet

ARCHIVED
type: Class
title: Archived Data
subclass of: DataMaturityLevel
definition: Long-term preservation with access controls

CLEANED
type: Class
title: Cleaned Data
subclass of: DataMaturityLevel
definition: Basic cleaning and validation applied

CURATED
type: Class
title: Curated Data
subclass of: DataMaturityLevel
definition: Expert-reviewed and validated

INTEGRATED
type: Class
title: Integrated Data
subclass of: DataMaturityLevel
definition: Combined with other data sources

PUBLISHED
type: Class
title: Published Data
subclass of: DataMaturityLevel
definition: Publicly available with proper metadata

RAW
type: Class
title: Raw Data
subclass of: DataMaturityLevel
definition: Unprocessed, uncleaned data

STANDARDIZED
type: Class
title: Standardized Data
subclass of: DataMaturityLevel
definition: Conforms to defined standards and formats

ALIGNED
type: Class
subclass of: DataProcessingLevel
definition: Aligned to reference genome

ANNOTATED
type: Class
subclass of: DataProcessingLevel
definition: Functionally annotated sequences

ASSEMBLED
type: Class
subclass of: DataProcessingLevel
definition: De novo assembled sequences

DEDUPLICATED
type: Class
subclass of: DataProcessingLevel
definition: PCR duplicates removed

NORMALIZED
type: Class
subclass of: DataProcessingLevel
definition: Expression normalized (RNA-seq)

QUALITY_FILTERED
type: Class
subclass of: DataProcessingLevel
definition: Quality filtered reads

RAW
type: Class
subclass of: DataProcessingLevel
definition: Raw unprocessed sequencing reads

RECALIBRATED
type: Class
subclass of: DataProcessingLevel
definition: Base quality score recalibrated

TRIMMED
type: Class
subclass of: DataProcessingLevel
definition: Adapter/quality trimmed reads

VARIANT_CALLED
type: Class
subclass of: DataProcessingLevel
definition: Variants called from alignments

DISCOVERY
type: Class
subclass of: DataServiceType
alternative label: Catalog Service
alternative label: Search Service
definition: Service enabling search and discovery of datasets and services.
inspire type: discovery

DOWNLOAD
type: Class
subclass of: DataServiceType
alternative label: Access Service
alternative label: Retrieval Service
definition: Service enabling bulk download of datasets or portions thereof.
inspire type: download

INVOKE
type: Class
subclass of: DataServiceType
alternative label: API Service
alternative label: Web Service
definition: Service enabling invocation of operations on data, typically through an API.
inspire type: invoke

QUERY
type: Class
subclass of: DataServiceType
alternative label: Query Service
alternative label: SPARQL Endpoint
definition: Service enabling query-based access to data, returning filtered or aggregated results.

SUBSCRIPTION
type: Class
subclass of: DataServiceType
alternative label: Event Service
alternative label: Notification Service
definition: Service enabling subscription to data updates or notifications.

TRANSFORMATION
type: Class
subclass of: DataServiceType
alternative label: Conversion Service
alternative label: Processing Service
definition: Service enabling transformation of data, such as format conversion or coordinate transformation.
inspire type: transformation

VIEW
type: Class
subclass of: DataServiceType
alternative label: Display Service
alternative label: Visualization Service
definition: Service enabling viewing or visualization of data without full download.
inspire type: view

BIT
type: Class
subclass of: DataSizeUnitEnum
definition: Bit (binary digit)
base: binary
symbol: bit

GIBIBYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Gibibyte (2^30 bytes)
conversion to byte: 1073741824
standard: binary
symbol: GiB

GIGABYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Gigabyte (10^9 bytes)
conversion to byte: 1e9
standard: decimal
symbol: GB

KIBIBYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Kibibyte (1024 bytes)
conversion to byte: 1024
standard: binary
symbol: KiB

MEBIBYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Mebibyte (2^20 bytes)
conversion to byte: 1048576
standard: binary
symbol: MiB

PETABYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Petabyte (10^15 bytes)
conversion to byte: 1e15
standard: decimal
symbol: PB

TEBIBYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Tebibyte (2^40 bytes)
conversion to byte: 1099511627776
standard: binary
symbol: TiB

TERABYTE
type: Class
subclass of: DataSizeUnitEnum
definition: Terabyte (10^12 bytes)
conversion to byte: 1e12
standard: decimal
symbol: TB

DIFFRACTION
type: Class
subclass of: DataType
definition: X-ray diffraction pattern
information: structure factors, crystal lattice

METADATA
type: Class
subclass of: DataType
definition: Associated metadata file
formats: STAR, XML, JSON

MICROGRAPH
type: Class
subclass of: DataType
definition: Electron micrograph image
typical size: 4k x 4k pixels

MODEL
type: Class
subclass of: DataType
definition: Atomic coordinate model
formats: PDB, mmCIF

MOVIE
type: Class
subclass of: DataType
definition: Movie stack of frames
applications: motion correction, dose fractionation

PARTICLES
type: Class
subclass of: DataType
definition: Particle stack for single particle analysis
format: boxed particles, aligned

SCATTERING
type: Class
subclass of: DataType
definition: Small-angle scattering data
information: I(q) vs scattering vector

TOMOGRAM
type: Class
subclass of: DataType
definition: 3D tomographic reconstruction
resolution: 5-50 Å typical

VOLUME
type: Class
subclass of: DataType
definition: 3D electron density volume
applications: cryo-EM maps, crystallographic maps

DataUseSchemaEnum
type: Class
subclass of: DataDomainEnum
definition: Schema-level enum for data_use in data
in scheme: merged
source file: data/data_use.yaml

JSONL
type: Class
subclass of: DatasetEncodingFormat
definition: JSON Lines format (newline-delimited JSON)
alt mime type: application/x-ndjson
mime type: application/jsonl

PARQUET
type: Class
subclass of: DatasetEncodingFormat
definition: Apache Parquet columnar storage format
mime type: application/parquet

PLAIN_TEXT
type: Class
subclass of: DatasetEncodingFormat
definition: Plain text files
mime type: text/plain

WAV
type: Class
subclass of: DatasetEncodingFormat
definition: Waveform Audio File Format
mime type: audio/wav

ALL
type: Class
subclass of: DatasetSplitType
definition: Complete dataset without splits

TEST
type: Class
subclass of: DatasetSplitType
definition: Test split used for final model evaluation
purpose: model evaluation
typical size: 10-20% of data

TRAIN
type: Class
subclass of: DatasetSplitType
definition: Training split used for model learning
purpose: model training
typical size: 60-80% of data

VALIDATION
type: Class
subclass of: DatasetSplitType
definition: Validation split used for hyperparameter tuning and model selection
aliases: val, dev
purpose: model tuning
typical size: 10-20% of data

AUTOCRATIC
type: Class
title: Autocratic Decision Making
subclass of: DecisionMakingStyleEnum
definition: Single decision-maker with full authority
authority: centralized decision authority
control: complete control
input: limited input from others
speed: fast decision making

COLLABORATIVE
type: Class
title: Collaborative Decision Making
subclass of: DecisionMakingStyleEnum
definition: Joint decision-making with shared responsibility
collaboration: collaborative approach
shared: shared responsibility
synergy: collective wisdom
teamwork: team-based decisions

COMMITTEE
type: Class
title: Committee Decision Making
subclass of: DecisionMakingStyleEnum
definition: Formal group decision-making structure
accountability: shared accountability
process: structured decision process
representation: stakeholder representation
structure: formal committee structure

CONSENSUS
type: Class
title: Consensus Decision Making
subclass of: DecisionMakingStyleEnum
definition: Agreement reached through group discussion
agreement: group agreement required
discussion: extensive group discussion
time: time-intensive process
unanimous: unanimous or near-unanimous agreement

CONSULTATIVE
type: Class
title: Consultative Decision Making
subclass of: DecisionMakingStyleEnum
definition: Leader consults others before deciding
authority: leader retains decision authority
consultation: stakeholder consultation
informed: informed decision making
input: seeks input and advice

CRISIS
type: Class
title: Crisis Decision Making
subclass of: DecisionMakingStyleEnum
definition: Rapid decision-making under crisis conditions
limited info: limited information available
risk: high-risk decision making
speed: rapid response required
urgency: urgent decision making

DATA_DRIVEN
type: Class
title: Data-Driven Decision Making
subclass of: DecisionMakingStyleEnum
definition: Decisions based on data analysis and evidence
analysis: analytical approach
data: data and analytics based
evidence: evidence-based decisions
objectivity: objective decision making

DELEGATED
type: Class
title: Delegated Decision Making
subclass of: DecisionMakingStyleEnum
definition: Decision authority delegated to others
accountability: delegated accountability
autonomy: decision autonomy
delegation: decision authority delegation
empowerment: employee empowerment

DEMOCRATIC
type: Class
title: Democratic Decision Making
subclass of: DecisionMakingStyleEnum
definition: Group participation in decision-making process
consensus: consensus building
input: diverse input and perspectives
ownership: shared ownership of decisions
participation: group participation

INTUITIVE
type: Class
title: Intuitive Decision Making
subclass of: DecisionMakingStyleEnum
definition: Decisions based on experience and gut feeling
creativity: creative and innovative
experience: leverages experience
intuition: intuition and experience based
speed: rapid decision making

CHARACTERIZATION
type: Class
subclass of: DecommissioningPhaseType
definition: Surveying and characterizing radiological and hazardous conditions at the facility

DISMANTLEMENT
type: Class
subclass of: DecommissioningPhaseType
definition: Physical demolition and removal of contaminated structures and equipment

LICENSE_TERMINATION
type: Class
subclass of: DecommissioningPhaseType
definition: Final regulatory review and release of the site from nuclear licensing requirements

LONG_TERM_MONITORING
type: Class
subclass of: DecommissioningPhaseType
broad match: ENVO_02500041
definition: Ongoing environmental monitoring after initial cleanup is complete

SITE_RESTORATION
type: Class
subclass of: DecommissioningPhaseType
definition: Restoring the site to a condition suitable for future use

WASTE_MANAGEMENT
type: Class
subclass of: DecommissioningPhaseType
definition: Processing, packaging, transporting, and disposing of radioactive waste

CRITICAL_DEFECT
type: Class
title: Critical Defect
subclass of: DefectClassificationEnum
alternative label: 3
alternative label: critical
alternative label: severe
definition: Critical defect rendering item unusable or unsafe

MAJOR_DEFECT
type: Class
title: Major Defect
subclass of: DefectClassificationEnum
alternative label: 2
alternative label: functional
alternative label: major
definition: Major defect affecting functionality

MINOR_DEFECT
type: Class
title: Minor Defect
subclass of: DefectClassificationEnum
alternative label: 1
alternative label: cosmetic
alternative label: minor
definition: Minor defect that doesn't affect functionality

LEVEL_1
type: Class
title: Level 1 - Prevention of Abnormal Operation
subclass of: DefenseInDepthLevelEnum
definition: Conservative design and high quality in construction and operation
approach: conservative design, quality assurance
examples: design margins, quality construction
objective: prevent deviations from normal operation

LEVEL_2
type: Class
title: Level 2 - Control of Abnormal Operation
subclass of: DefenseInDepthLevelEnum
definition: Control of abnormal operation and detection of failures
approach: control systems, protection systems
examples: reactor protection systems, safety systems
objective: control abnormal operation and failures

LEVEL_3
type: Class
title: Level 3 - Control of Accidents Within Design Basis
subclass of: DefenseInDepthLevelEnum
definition: Control of accidents to prevent progression to severe conditions
approach: engineered safety features
examples: emergency core cooling, containment systems
objective: control design basis accidents

LEVEL_4
type: Class
title: Level 4 - Control of Severe Plant Conditions
subclass of: DefenseInDepthLevelEnum
definition: Control of severe accidents including prevention of core melt progression
approach: severe accident management
examples: cavity flooding, filtered venting
objective: control severe accidents

LEVEL_5
type: Class
title: Level 5 - Mitigation of Radiological Consequences
subclass of: DefenseInDepthLevelEnum
definition: Mitigation of off-site radiological consequences
approach: emergency planning and response
examples: evacuation plans, protective actions
objective: protect public and environment

FRET
type: Class
subclass of: DetectionModeEnum
definition: Fluorescence resonance energy transfer detection
full name: Fluorescence Resonance Energy Transfer

HYBRIDIZATION_PROBE
type: Class
title: hybridization probe
subclass of: DetectionModeEnum
definition: Two-probe FRET-based detection

MOLECULAR_BEACON
type: Class
title: molecular beacon
subclass of: DetectionModeEnum
definition: Hairpin probe-based detection

MULTI_CHANNEL
type: Class
title: multi-channel
subclass of: DetectionModeEnum
definition: Multi-channel fluorescence detection

SCORPION
type: Class
title: Scorpion
subclass of: DetectionModeEnum
definition: Unimolecular probe-based detection

SYBR_GREEN
type: Class
title: SYBR Green
subclass of: DetectionModeEnum
definition: DNA-binding dye detection

TAQMAN
type: Class
title: TaqMan
subclass of: DetectionModeEnum
definition: Hydrolysis probe-based detection

CMOS
type: Class
subclass of: Detector
definition: Complementary metal-oxide semiconductor detector
advantages: fast readout, low noise

DIRECT_ELECTRON
type: Class
subclass of: Detector
definition: Direct electron detector (DED)
advantages: high DQE, fast readout
examples: K2, K3, Falcon, DE-series

HYBRID_PIXEL
type: Class
subclass of: Detector
definition: Hybrid pixel detector
advantages: photon counting, zero noise
examples: Pilatus, Eiger

PHOTOSTIMULABLE_PHOSPHOR
type: Class
subclass of: Detector
definition: Photostimulable phosphor (image plate)
applications: legacy crystallography

CALORIMETER
type: Class
subclass of: DetectorType
definition: Detector that measures the total energy of incident particles by absorbing them

CHERENKOV_DETECTOR
type: Class
subclass of: DetectorType
definition: Detector that identifies particles by measuring Cherenkov radiation emitted in a medium

DRIFT_CHAMBER
type: Class
subclass of: DetectorType
definition: Gas-filled wire chamber that measures particle positions from electron drift times

MUON_SPECTROMETER
type: Class
subclass of: DetectorType
definition: Large detector system designed to identify and measure the momentum of muons

SCINTILLATOR
type: Class
subclass of: DetectorType
definition: Detector using scintillating material that emits light when traversed by ionizing radiation

SILICON_STRIP_DETECTOR
type: Class
subclass of: DetectorType
definition: Semiconductor detector using finely segmented silicon strips for precise position measurement

TIME_PROJECTION_CHAMBER
type: Class
subclass of: DetectorType
definition: Gas-filled detector that provides three-dimensional particle track reconstruction

TRACKING_DETECTOR
type: Class
subclass of: DetectorType
definition: Detector that records the trajectories of charged particles

DevicesSchemaEnum
type: Class
subclass of: LabAutomationDomainEnum
definition: Schema-level enum for devices in lab_automation
in scheme: merged
source file: lab_automation/devices.yaml

EEG
type: Class
title: Electroencephalogram
subclass of: DiagnosticTestTypeEnum
alternative label: Djibouti
measures: brain electrical activity

URINE_TEST
type: Class
title: Urine sample analysis
subclass of: DiagnosticTestTypeEnum
alternative label: Tissue Factor
types: urinalysis, culture, drug screen

DOC
type: Class
subclass of: DocumentFormatEnum
definition: Microsoft Word legacy format
application: Microsoft Word (legacy)
extension: .doc
mime type: application/msword

DOCX
type: Class
subclass of: DocumentFormatEnum
definition: Microsoft Word Open XML
application: Microsoft Word
extension: .docx
mime type: application/vnd.openxmlformats-officedocument.wordprocessingml.document

EPUB
type: Class
subclass of: DocumentFormatEnum
definition: Electronic Publication
extension: .epub
mime type: application/epub+zip
use: e-books

MARKDOWN
type: Class
subclass of: DocumentFormatEnum
definition: Markdown formatted text
extension: .md, .markdown
mime type: text/markdown

ODT
type: Class
subclass of: DocumentFormatEnum
definition: OpenDocument Text
application: LibreOffice, OpenOffice
extension: .odt
mime type: application/vnd.oasis.opendocument.text

RTF
type: Class
subclass of: DocumentFormatEnum
definition: Rich Text Format
extension: .rtf
mime type: application/rtf

HOMOGENIZATION
type: Class
subclass of: DownstreamProcessEnum
definition: Cell disruption/homogenization
methods: High pressure, bead mill

DISPENSED_IN_OUTPATIENT_OFFICE
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: DISPENSED IN OUTPATIENT OFFICE
definition: Drug dispensed in outpatient office

INPATIENT_ADMINISTRATION
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: INPATIENT ADMINISTRATION
definition: Drug administered during inpatient stay

MEDICATION_LIST_ENTRY
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: MEDICATION LIST ENTRY
definition: Drug from medication list

NLP_DERIVED
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: NLP DERIVED
definition: Drug exposure derived through NLP

PATIENT_SELF_REPORTED_MEDICATION
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PATIENT SELF-REPORTED MEDICATION
definition: Medication reported by patient

PHYSICIAN_ADMINISTERED_DRUG_AS_PROCEDURE
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PHYSICIAN ADMINISTERED DRUG (IDENTIFIED AS PROCEDURE)
definition: Drug administered as procedure

PHYSICIAN_ADMINISTERED_DRUG_FROM_EHR_ORDER
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PHYSICIAN ADMINISTERED DRUG (IDENTIFIED FROM EHR ORDER)
definition: Drug administered by physician from EHR order

PRESCRIPTION_DISPENSED_IN_PHARMACY
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PRESCRIPTION DISPENSED IN PHARMACY
definition: Prescription dispensed at pharmacy

PRESCRIPTION_DISPENSED_THROUGH_MAIL_ORDER
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PRESCRIPTION DISPENSED THROUGH MAIL ORDER
definition: Prescription dispensed via mail order

PRESCRIPTION_WRITTEN
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: PRESCRIPTION WRITTEN
definition: Prescription written by provider

RANDOMIZED_DRUG
type: Class
subclass of: DrugExposureProvenanceEnum
alternative label: RANDOMIZED DRUG
definition: Drug from clinical trial randomization

CARCINOGENIC_TO_HUMANS
type: Class
title: Carcinogenic to Humans
subclass of: EPAIRISCarcinogenicityGroup
definition: Strong evidence of human carcinogenicity. This descriptor is appropriate when there is convincing epidemiologic evidence of a causal association between human exposure and cancer.
evidence: convincing epidemiologic evidence
legacy group: A

GROUP_A
type: Class
title: Group A - Human Carcinogen (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. Sufficient evidence from epidemiologic studies to support a causal association between exposure and cancer.
status: legacy
superseded by: CARCINOGENIC_TO_HUMANS

GROUP_B1
type: Class
title: Group B1 - Probable Human Carcinogen (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. Limited evidence of carcinogenicity from epidemiologic studies.
status: legacy
superseded by: LIKELY_CARCINOGENIC

GROUP_B2
type: Class
title: Group B2 - Probable Human Carcinogen (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. Sufficient evidence from animal studies and inadequate evidence from epidemiologic studies.
status: legacy
superseded by: LIKELY_CARCINOGENIC

GROUP_C
type: Class
title: Group C - Possible Human Carcinogen (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. Limited evidence of carcinogenicity in animals in the absence of human data.
status: legacy
superseded by: SUGGESTIVE_EVIDENCE

GROUP_D
type: Class
title: Group D - Not Classifiable (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. Inadequate human and animal evidence of carcinogenicity or no data available.
status: legacy
superseded by: INADEQUATE_INFORMATION

GROUP_E
type: Class
title: Group E - Evidence of Non-Carcinogenicity (Legacy)
subclass of: EPAIRISCarcinogenicityGroup
definition: Legacy EPA classification. No evidence of carcinogenicity in at least two adequate animal tests or in adequate epidemiologic and animal studies.
status: legacy
superseded by: NOT_LIKELY_CARCINOGENIC

INADEQUATE_INFORMATION
type: Class
title: Inadequate Information to Assess Carcinogenic Potential
subclass of: EPAIRISCarcinogenicityGroup
definition: Available data are inadequate for an assessment of human carcinogenic potential.
evidence: inadequate data
legacy group: D

LIKELY_CARCINOGENIC
type: Class
title: Likely to Be Carcinogenic to Humans
subclass of: EPAIRISCarcinogenicityGroup
definition: Evidence is adequate to demonstrate carcinogenic potential to humans but does not reach the weight of evidence for Carcinogenic to Humans.
evidence: adequate evidence
legacy group: B1/B2

NOT_LIKELY_CARCINOGENIC
type: Class
title: Not Likely to Be Carcinogenic to Humans
subclass of: EPAIRISCarcinogenicityGroup
definition: Available data are considered robust for deciding that there is no basis for human hazard concern.
evidence: robust evidence of no hazard
legacy group: E

SUGGESTIVE_EVIDENCE
type: Class
title: Suggestive Evidence of Carcinogenic Potential
subclass of: EPAIRISCarcinogenicityGroup
definition: Evidence is suggestive of carcinogenicity but not sufficient to assess human carcinogenic potential.
evidence: suggestive but not sufficient
legacy group: C

PRIMARY_SECTOR
type: Class
title: Primary Sector
subclass of: EconomicSectorEnum
definition: Economic activities extracting natural resources
activities: agriculture, mining, forestry, fishing
development stage: dominant in early economic development
employment: typically lower employment share in developed economies
output: raw materials and natural resources

QUATERNARY_SECTOR
type: Class
title: Quaternary Sector
subclass of: EconomicSectorEnum
definition: Knowledge-based economic activities
activities: research, education, information technology, consulting
characteristics: high skill and education requirements
growth: rapidly growing in knowledge economies
output: knowledge, information, and intellectual services

QUINARY_SECTOR
type: Class
title: Quinary Sector
subclass of: EconomicSectorEnum
definition: High-level decision-making and policy services
activities: top-level government, healthcare, education, culture
characteristics: elite services and leadership roles
output: highest level services and decision-making
scope: limited to highest level activities

SECONDARY_SECTOR
type: Class
title: Secondary Sector
subclass of: EconomicSectorEnum
definition: Economic activities manufacturing and processing goods
activities: manufacturing, construction, utilities
employment: historically significant in industrial economies
output: processed and manufactured goods
value added: transforms raw materials into finished products

TERTIARY_SECTOR
type: Class
title: Tertiary Sector
subclass of: EconomicSectorEnum
definition: Economic activities providing services
activities: retail, hospitality, transportation, finance, healthcare
employment: dominant employment sector
growth: largest and fastest growing sector in developed economies
output: services to consumers and businesses

EIGHTH_GRADE_OR_LESS
type: Class
subclass of: EducationalAttainmentEnum
alternative label: 8TH_GRADE_OR_LESS
alternative label: elementary
definition: Completed 8th grade or less

SOME_COLLEGE_NO_DEGREE
type: Class
subclass of: EducationalAttainmentEnum
alternative label: SOME_COLLEGE_OR_TECH_NO_DEGREE
definition: Some college or technical school but no degree

CONDUCTOR
type: Class
title: Conductor
subclass of: ElectricalConductivityEnum
alternative label: metal
definition: Material with high electrical conductivity (resistivity < 10^-5 Ω·m)

INSULATOR
type: Class
title: Insulator
subclass of: ElectricalConductivityEnum
alternative label: dielectric
definition: Material with very low electrical conductivity (resistivity > 10^8 Ω·m)

SUPERCONDUCTOR
type: Class
title: Superconductor
subclass of: ElectricalConductivityEnum
definition: Material with zero electrical resistance below critical temperature

GREEN_YELLOW_GROUND
type: Class
subclass of: ElectricalWireColorEnum
definition: Green with yellow stripe - ground/earth (International)
function: ground/earth
pattern: green with yellow stripe
region: IEC standard

ANCILLARY_SERVICES
type: Class
subclass of: ElectricityMarket
definition: Ancillary services market

BILATERAL
type: Class
subclass of: ElectricityMarket
definition: Bilateral contracts

CAPACITY_MARKET
type: Class
subclass of: ElectricityMarket
definition: Capacity market

DAY_AHEAD
type: Class
subclass of: ElectricityMarket
definition: Day-ahead market

FEED_IN_TARIFF
type: Class
subclass of: ElectricityMarket
definition: Feed-in tariff

FUTURES
type: Class
subclass of: ElectricityMarket
definition: Futures market

INTRADAY
type: Class
subclass of: ElectricityMarket
definition: Intraday market

NET_METERING
type: Class
subclass of: ElectricityMarket
definition: Net metering

POWER_PURCHASE_AGREEMENT
type: Class
subclass of: ElectricityMarket
definition: Power purchase agreement (PPA)

SPOT_MARKET
type: Class
subclass of: ElectricityMarket
definition: Spot market/real-time pricing

POST_TRANSITION_METALS
type: Class
subclass of: ElementFamilyEnum
definition: Metals after the transition series
elements: Al, Ga, In, Tl, Sn, Pb, Bi

ALERT
type: Class
title: Alert
subclass of: EmergencyClassificationEnum
definition: Events involving actual or potential substantial degradation of plant safety
emergency response: partial activation
off site response: notification and standby
plant status: substantial safety degradation possible
public protective actions: none required, but preparation
severity: second emergency level

GENERAL_EMERGENCY
type: Class
title: General Emergency
subclass of: EmergencyClassificationEnum
definition: Events involving actual or imminent substantial core degradation
emergency response: maximum response
off site response: full activation
plant status: core degradation or containment failure
public protective actions: implementation likely
severity: highest emergency level

NOTIFICATION_UNUSUAL_EVENT
type: Class
title: Notification of Unusual Event (NOUE)
subclass of: EmergencyClassificationEnum
alternative label: NOUE
alternative label: Unusual Event
definition: Events that are in process or have occurred which indicate potential degradation
emergency response: minimal activation
off site response: notification only
public protective actions: none required
severity: lowest emergency level

SITE_AREA_EMERGENCY
type: Class
title: Site Area Emergency (SAE)
subclass of: EmergencyClassificationEnum
alternative label: SAE
definition: Events with actual or likely major failures of plant protective systems
emergency response: full activation
off site response: offsite centers activated
plant status: major plant safety systems failure
public protective actions: may be required near site
severity: third emergency level

SCOPE_1
type: Class
subclass of: EmissionScope
definition: Direct emissions from owned or controlled sources
related match: OEO_00000199
ghg protocol: Scope 1
oeo label: greenhouse gas emission

SCOPE_2
type: Class
subclass of: EmissionScope
definition: Indirect emissions from purchased energy
related match: OEO_00000199
ghg protocol: Scope 2
oeo label: greenhouse gas emission

SCOPE_3
type: Class
subclass of: EmissionScope
definition: All other indirect emissions in value chain
related match: OEO_00000199
ghg protocol: Scope 3
oeo label: greenhouse gas emission

SCOPE_3_DOWNSTREAM
type: Class
subclass of: EmissionScope
definition: Downstream Scope 3 emissions
related match: OEO_00000199
ghg protocol: Scope 3
oeo label: greenhouse gas emission

SCOPE_3_UPSTREAM
type: Class
subclass of: EmissionScope
definition: Upstream Scope 3 emissions
related match: OEO_00000199
ghg protocol: Scope 3
oeo label: greenhouse gas emission

EmotionClassificationSchemaEnum
type: Class
subclass of: DataScienceDomainEnum
definition: Schema-level enum for emotion_classification in data_science
in scheme: merged
source file: data_science/emotion_classification.yaml

ACTIVE
type: Class
title: Active Employment
subclass of: EmployeeStatusEnum
definition: Currently employed and working
benefits: receiving full benefits
engagement: expected engagement
performance: subject to performance management
responsibilities: fulfilling job responsibilities
status: actively working

ON_LEAVE
type: Class
title: On Leave
subclass of: EmployeeStatusEnum
definition: Temporarily away from work on approved leave
approval: approved leave
benefits: may retain benefits
return: expected return date
temporary: temporary absence
types: medical, family, personal leave

PROBATIONARY
type: Class
title: Probationary Period
subclass of: EmployeeStatusEnum
definition: New employee in probationary period
assessment: performance assessment
benefits: limited or delayed benefits
duration: defined probationary period
evaluation: ongoing evaluation
termination: easier termination

RETIRED
type: Class
title: Retired
subclass of: EmployeeStatusEnum
definition: Retired from employment
age: retirement age
benefits: retirement benefits
service: completed service
transition: career transition
voluntary: voluntary departure

SUSPENDED
type: Class
title: Suspended
subclass of: EmployeeStatusEnum
definition: Temporarily suspended from work
disciplinary: disciplinary action
investigation: pending investigation
pay: with or without pay
review: pending review
temporary: temporary status

TERMINATED
type: Class
title: Terminated
subclass of: EmployeeStatusEnum
definition: Employment has been terminated
benefits: benefits cessation
documentation: termination documentation
end: employment ended
final: final status
voluntary: voluntary or involuntary

CONSULTANT
type: Class
title: Consultant
subclass of: EmploymentTypeEnum
definition: Professional consulting services
expertise: specialized expertise
independence: independent professional
project: project or retainer basis
relationship: advisory relationship
value: strategic value-add

CONTRACT
type: Class
title: Contract Employment
subclass of: EmploymentTypeEnum
definition: Fixed-term contractual employment
benefits: limited benefits
duration: defined contract period
purpose: specific project or duration
relationship: contractual relationship
termination: defined end date

FREELANCE
type: Class
title: Freelance/Independent Contractor
subclass of: EmploymentTypeEnum
definition: Independent contractor or freelance work
benefits: no traditional benefits
control: high work autonomy
projects: project-based work
relationship: independent contractor
taxes: responsible for own taxes

FULL_TIME
type: Class
title: Full-Time Employment
subclass of: EmploymentTypeEnum
definition: Regular full-time employment status
benefits: full benefits package
classification: exempt or non-exempt
commitment: full organizational commitment
hours: typically 40 hours per week
stability: permanent position

INTERN
type: Class
title: Internship
subclass of: EmploymentTypeEnum
definition: Student or entry-level internship program
compensation: may be paid or unpaid
duration: limited duration
education: educational component
purpose: learning and experience
supervision: mentorship and guidance

PART_TIME
type: Class
title: Part-Time Employment
subclass of: EmploymentTypeEnum
definition: Regular part-time employment status
benefits: limited or prorated benefits
classification: typically non-exempt
commitment: ongoing but reduced hours
flexibility: flexible scheduling
hours: less than full-time hours

SEASONAL
type: Class
title: Seasonal Employment
subclass of: EmploymentTypeEnum
definition: Employment tied to seasonal business needs
benefits: limited benefits
duration: specific seasons
industry: retail, agriculture, tourism
pattern: recurring seasonal pattern
return: potential for seasonal return

TEMPORARY
type: Class
title: Temporary Employment
subclass of: EmploymentTypeEnum
definition: Short-term temporary employment
agency: often through staffing agency
benefits: minimal benefits
duration: short-term assignment
flexibility: high flexibility
purpose: seasonal or project work

VOLUNTEER
type: Class
title: Volunteer
subclass of: EmploymentTypeEnum
definition: Unpaid volunteer service
commitment: voluntary commitment
compensation: unpaid service
motivation: altruistic motivation
purpose: mission-driven work
recognition: non-monetary recognition

A
type: Class
subclass of: EnergyEfficiencyRating
definition: A
rank: 4
region: EU

A_PLUS
type: Class
subclass of: EnergyEfficiencyRating
definition: A+
rank: 3
region: EU

A_PLUS_PLUS
type: Class
subclass of: EnergyEfficiencyRating
definition: A++
rank: 2
region: EU

A_PLUS_PLUS_PLUS
type: Class
subclass of: EnergyEfficiencyRating
definition: A+++ (highest efficiency)
rank: 1
region: EU

B
type: Class
subclass of: EnergyEfficiencyRating
definition: B
rank: 5
region: EU

C
type: Class
subclass of: EnergyEfficiencyRating
definition: C
rank: 6
region: EU

D
type: Class
subclass of: EnergyEfficiencyRating
definition: D
rank: 7
region: EU

E
type: Class
subclass of: EnergyEfficiencyRating
definition: E
rank: 8
region: EU

ENERGY_STAR
type: Class
subclass of: EnergyEfficiencyRating
definition: Energy Star certified
region: US

ENERGY_STAR_MOST_EFFICIENT
type: Class
subclass of: EnergyEfficiencyRating
definition: Energy Star Most Efficient
region: US

F
type: Class
subclass of: EnergyEfficiencyRating
definition: F
rank: 9
region: EU

G
type: Class
subclass of: EnergyEfficiencyRating
definition: G (lowest efficiency)
rank: 10
region: EU

BATTERY_STORAGE
type: Class
subclass of: EnergySource
definition: Battery storage systems
oeo label: battery
storage: true

BIOFUEL
type: Class
title: Biofuels (ethanol, biodiesel)
subclass of: EnergySource
emission free: false
oeo label: biofuel
renewable: true

BIOMASS
type: Class
title: Biomass and bioenergy
subclass of: EnergySource
alternative label: organic material
related match: ENVO_01000155
emission free: false
oeo label: bioenergy
renewable: true

GASOLINE
type: Class
title: Gasoline/petrol
subclass of: EnergySource
alternative label: fuel oil
related match: ENVO_00002983
emission free: false
fossil fuel: true
oeo label: gasoline fuel
renewable: false

GRID_MIX
type: Class
title: Grid electricity (mixed sources)
subclass of: EnergySource
oeo label: supply grid
renewable: partial

HYDROELECTRIC
type: Class
title: Hydroelectric power
subclass of: EnergySource
alternative label: hydroelectric dam
related match: ENVO_00000468
emission free: true
oeo label: hydro energy
renewable: true

NUCLEAR_FISSION
type: Class
title: Nuclear fission
subclass of: EnergySource
alternative label: nuclear energy
related match: ENVO_2000025
emission free: true
oeo label: nuclear fuel
renewable: false

NUCLEAR_FUSION
type: Class
title: Nuclear fusion (experimental)
subclass of: EnergySource
alternative label: nuclear energy
related match: ENVO_2000025
emission free: true
renewable: false

TIDAL
type: Class
title: Tidal and wave energy
subclass of: EnergySource
emission free: true
oeo label: marine tidal energy, marine wave energy
renewable: true

WIND
type: Class
title: Wind power
subclass of: EnergySource
alternative label: wind wave energy
broad match: Wind
related match: ENVO_2000033
emission free: true
oeo label: wind energy
renewable: true

BATTERY
type: Class
subclass of: EnergyStorageType
definition: Battery storage (see BatteryType for specific chemistries)
category: electrochemical

COMPRESSED_AIR
type: Class
subclass of: EnergyStorageType
definition: Compressed air energy storage (CAES)
category: mechanical
oeo label: compressed air

FLYWHEEL
type: Class
subclass of: EnergyStorageType
definition: Flywheel energy storage
category: mechanical

GRAVITY_STORAGE
type: Class
subclass of: EnergyStorageType
definition: Gravity-based storage
category: mechanical

HYDROGEN_STORAGE
type: Class
subclass of: EnergyStorageType
definition: Hydrogen storage
category: chemical
oeo label: hydrogen

ICE_STORAGE
type: Class
subclass of: EnergyStorageType
definition: Ice thermal storage
category: thermal

MOLTEN_SALT
type: Class
subclass of: EnergyStorageType
definition: Molten salt thermal storage
category: thermal

PHASE_CHANGE
type: Class
subclass of: EnergyStorageType
definition: Phase change materials
category: thermal

PUMPED_HYDRO
type: Class
subclass of: EnergyStorageType
definition: Pumped hydroelectric storage
category: mechanical
oeo label: pumped hydro storage power plant

SUPERCAPACITOR
type: Class
subclass of: EnergyStorageType
definition: Supercapacitor
category: electrical

SUPERCONDUCTING
type: Class
subclass of: EnergyStorageType
definition: Superconducting magnetic energy storage (SMES)
category: electrical

SYNTHETIC_FUEL
type: Class
subclass of: EnergyStorageType
definition: Synthetic fuel storage
category: chemical
oeo label: synthetic fuel

TCE
type: Class
subclass of: EnergyUnit
definition: Tonne of coal equivalent
joules: 2.93e10
symbol: tce
ucum: tce

AERODYNAMIC_SEPARATION
type: Class
subclass of: EnrichmentProcessEnum
definition: Aerodynamic enrichment processes

ELECTROMAGNETIC_SEPARATION
type: Class
subclass of: EnrichmentProcessEnum
definition: Electromagnetic isotope separation (EMIS)

GAS_CENTRIFUGE
type: Class
subclass of: EnrichmentProcessEnum
definition: Gas centrifuge enrichment process

GAS_DIFFUSION
type: Class
subclass of: EnrichmentProcessEnum
definition: Gaseous diffusion enrichment process

LASER_ISOTOPE_SEPARATION
type: Class
subclass of: EnrichmentProcessEnum
definition: Laser-based uranium isotope separation

BIODIVERSITY_LOSS
type: Class
subclass of: EnvironmentalImpact
definition: Biodiversity loss
impact: species extinction, ecosystem disruption

SUBSIDENCE
type: Class
subclass of: EnvironmentalImpact
definition: Ground subsidence
cause: underground voids

TAILINGS
type: Class
subclass of: EnvironmentalImpact
definition: Tailings contamination
storage: tailings ponds, dams

EventsSchemaEnum
type: Class
subclass of: PreservationDomainEnum
definition: Schema-level enum for events in preservation
in scheme: merged
source file: preservation/events.yaml

AUTOMATED
type: Class
title: automated
subclass of: ExecutionModeEnum
definition: Fully automated execution without human intervention

DRY_RUN
type: Class
title: dry run
subclass of: ExecutionModeEnum
definition: Test execution without actual operations

MANUAL
type: Class
title: manual
subclass of: ExecutionModeEnum
definition: Manual execution by human operator

SEMI_AUTOMATED
type: Class
title: semi-automated
subclass of: ExecutionModeEnum
definition: Combination of automated and manual steps

SIMULATION
type: Class
title: simulation
subclass of: ExecutionModeEnum
definition: Simulated execution for testing and validation

SUPERVISED
type: Class
title: supervised
subclass of: ExecutionModeEnum
definition: Automated execution with human supervision

ACTIVE_LEARNING
type: Class
subclass of: ExperimentalDesignMethodType
definition: Machine learning approach that iteratively selects the most informative experiments to perform
approach: query-based learning from unlabeled data

BAYESIAN_OPTIMIZATION
type: Class
subclass of: ExperimentalDesignMethodType
definition: Probabilistic model-based optimization using Bayesian inference to guide experimental selection
approach: surrogate model with acquisition function

DESIGN_OF_EXPERIMENTS
type: Class
subclass of: ExperimentalDesignMethodType
definition: Classical statistical methods for planning experiments including factorial and response surface designs
approaches: full factorial, fractional factorial, Box-Behnken, central composite

EVOLUTIONARY_ALGORITHM
type: Class
subclass of: ExperimentalDesignMethodType
definition: Optimization method inspired by biological evolution using mutation, crossover, and selection
approach: population-based metaheuristic

GRID_SEARCH
type: Class
subclass of: ExperimentalDesignMethodType
definition: Systematic exploration of parameter space using a regular grid of experimental conditions
approach: exhaustive grid evaluation

LATIN_HYPERCUBE_SAMPLING
type: Class
subclass of: ExperimentalDesignMethodType
definition: Statistical sampling method that ensures even coverage of each parameter dimension
approach: stratified random sampling

MULTI_OBJECTIVE_OPTIMIZATION
type: Class
subclass of: ExperimentalDesignMethodType
definition: Optimization approach that simultaneously considers multiple competing objectives
approach: Pareto-optimal solution search

RANDOM_SEARCH
type: Class
subclass of: ExperimentalDesignMethodType
definition: Experimental design using random sampling of the parameter space
approach: random sampling

REINFORCEMENT_LEARNING
type: Class
subclass of: ExperimentalDesignMethodType
definition: Machine learning approach where an agent learns optimal experimental strategies through trial and reward
approach: reward-based sequential decision making

ENDOGENOUS_LEVEL
type: Class
subclass of: ExperimentalPreparation
definition: Physiological expression

IN_VITRO_EXPRESSION
type: Class
subclass of: ExperimentalPreparation
definition: Cell-free expression

KNOCKDOWN
type: Class
subclass of: ExperimentalPreparation
definition: Reduced expression

NATIVE_SOURCE
type: Class
subclass of: ExperimentalPreparation
definition: From original organism

RECOMBINANT_EXPRESSION
type: Class
subclass of: ExperimentalPreparation
definition: Expressed in heterologous system

ALLERGEN
type: Class
title: Aeroallergen
subclass of: ExposureAgentCategoryEnum
definition: Airborne allergens including pollen, mold spores, and other biological particles triggering allergic responses.
examples: tree pollen, grass pollen, ragweed, mold spores

BLUE_SPACE
type: Class
title: Blue space
subclass of: ExposureAgentCategoryEnum
definition: Access to and proximity to water bodies including lakes, rivers, and coastal areas.
metrics: distance to water, water body area

BUILT_ENVIRONMENT
type: Class
title: Built environment
subclass of: ExposureAgentCategoryEnum
definition: Characteristics of the human-made environment including walkability, food access, and housing quality.
metrics: walkability score, food desert index, housing age

CRITERIA_AIR_POLLUTANT
type: Class
title: Criteria air pollutant
subclass of: ExposureAgentCategoryEnum
definition: EPA-regulated criteria air pollutants under the Clean Air Act: PM2.5, PM10, O3, NO2, SO2, CO, and Pb.
examples: PM2.5, PM10, O3, NO2, SO2, CO, Pb
regulatory: EPA NAAQS

EXTREME_COLD
type: Class
title: Extreme cold
subclass of: ExposureAgentCategoryEnum
definition: Ambient cold exposure characterized by temperature or wind chill.
metrics: temperature, wind chill

EXTREME_HEAT
type: Class
title: Extreme heat
subclass of: ExposureAgentCategoryEnum
definition: Ambient heat exposure characterized by temperature, heat index, or other thermal comfort metrics.
metrics: temperature, heat index, WBGT, apparent temperature

GREEN_SPACE
type: Class
title: Green space
subclass of: ExposureAgentCategoryEnum
definition: Access to and amount of vegetated areas including parks, forests, and urban greenery. Associated with mental and physical health benefits.
metrics: NDVI, park access, tree canopy cover

HAZARDOUS_AIR_POLLUTANT
type: Class
title: Hazardous air pollutant
subclass of: ExposureAgentCategoryEnum
definition: EPA-designated hazardous air pollutants (HAPs) known to cause cancer or other serious health effects.
examples: benzene, formaldehyde, acetaldehyde
regulatory: EPA HAPs list (187 pollutants)

LIGHT_POLLUTION
type: Class
title: Light pollution
subclass of: ExposureAgentCategoryEnum
definition: Artificial light at night from urban and industrial sources. Associated with circadian disruption.
metrics: radiance, sky brightness

NOISE
type: Class
title: Environmental noise
subclass of: ExposureAgentCategoryEnum
definition: Ambient noise from traffic, airports, industry, and other sources. Associated with cardiovascular and mental health effects.
metrics: Lden, Lnight, LAeq

RADIONUCLIDE
type: Class
title: Radionuclide
subclass of: ExposureAgentCategoryEnum
definition: Naturally occurring or anthropogenic radioactive materials in the environment, including radon gas.
examples: radon-222, uranium, radium

SOCIOECONOMIC_DEPRIVATION
type: Class
title: Socioeconomic deprivation
subclass of: ExposureAgentCategoryEnum
definition: Area-level measures of socioeconomic disadvantage that modify or mediate environmental health effects.
indices: ADI, NDI, SVI

SOIL_CONTAMINANT
type: Class
title: Soil contaminant
subclass of: ExposureAgentCategoryEnum
definition: Chemical contaminants in soil that may affect health through direct contact, ingestion, or vapor intrusion.
examples: lead, arsenic, petroleum, pesticides

UV_RADIATION
type: Class
title: UV radiation
subclass of: ExposureAgentCategoryEnum
definition: Solar ultraviolet radiation exposure, particularly UVB relevant to skin cancer and vitamin D synthesis.
metrics: UV index, erythemal UV dose

VECTOR_HABITAT
type: Class
title: Vector habitat suitability
subclass of: ExposureAgentCategoryEnum
definition: Environmental conditions favoring disease vector populations (mosquitoes, ticks) based on climate and land use.
diseases: dengue, Zika, Lyme disease
vectors: Aedes mosquitoes, Ixodes ticks

WATER_CONTAMINANT
type: Class
title: Water contaminant
subclass of: ExposureAgentCategoryEnum
definition: Chemical, biological, or physical contaminants in drinking water or recreational water bodies.
examples: lead, arsenic, nitrates, PFAS, pathogens

WILDFIRE_SMOKE
type: Class
title: Wildfire smoke
subclass of: ExposureAgentCategoryEnum
definition: Smoke from wildfires containing PM2.5, CO, VOCs, and other combustion products. Distinct from anthropogenic air pollution.
components: PM2.5, CO, VOCs, PAHs

ACUTE
type: Class
subclass of: ExposureDurationEnum
definition: Single or short-term exposure (hours to days)

CHRONIC
type: Class
subclass of: ExposureDurationEnum
definition: Long-term exposure over years

DEVELOPMENTAL
type: Class
subclass of: ExposureDurationEnum
definition: Exposure during critical developmental periods

LIFETIME
type: Class
subclass of: ExposureDurationEnum
definition: Exposure over entire lifetime

POSTNATAL
type: Class
subclass of: ExposureDurationEnum
definition: Exposure after birth

PRENATAL
type: Class
subclass of: ExposureDurationEnum
definition: Exposure during pregnancy

SUBACUTE
type: Class
subclass of: ExposureDurationEnum
definition: Repeated exposure over weeks

SUBCHRONIC
type: Class
subclass of: ExposureDurationEnum
definition: Repeated exposure over months

ExposureFrequencyEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Exposure Frequency
status: DRAFT
subclass of: ExposuresSchemaEnum
union of: INTERMITTENT
union of: CONTINUOUS
definition: Temporal pattern of exposure occurrence
in scheme: merged
permissible values: INTERMITTENT
permissible values: CONTINUOUS
source domain: environmental_health
source schema: exposures

INTRAMUSCULAR
type: Class
subclass of: ExposureRouteEnum
definition: Exposure through muscle tissue
related match: ExO_0000062

INTRAVASCULAR
type: Class
subclass of: ExposureRouteEnum
definition: Exposure through blood vessels
related match: ExO_0000063

MULTIPLE_ROUTES
type: Class
subclass of: ExposureRouteEnum
definition: Exposure through multiple pathways

SUBCUTANEOUS
type: Class
subclass of: ExposureRouteEnum
definition: Exposure through subcutaneous tissue
related match: ExO_0000061

AGRICULTURAL
type: Class
subclass of: ExposureSourceEnum
definition: Agricultural activities
related match: ENVO_00000077
related match: ENVO_01000311

AMBIENT_AIR
type: Class
subclass of: ExposureSourceEnum
definition: Outdoor air pollution
related match: ENVO_01000676
related match: ExO_0000020

CONSTRUCTION
type: Class
subclass of: ExposureSourceEnum
definition: Construction-related exposure
related match: ENVO_01000996

CONSUMER_PRODUCTS
type: Class
subclass of: ExposureSourceEnum
definition: Household and consumer products
related match: ENVO_00003074
related match: ENVO_03501339

DRINKING_WATER
type: Class
subclass of: ExposureSourceEnum
definition: Contaminated drinking water
related match: ENVO_00002186
related match: ENVO_00003064

FOOD
type: Class
subclass of: ExposureSourceEnum
definition: Contaminated food
related match: CHEBI_33290

INDOOR_AIR
type: Class
subclass of: ExposureSourceEnum
definition: Indoor air pollution
related match: ENVO_01000676
related match: ExO_0000019

INDUSTRIAL_EMISSIONS
type: Class
subclass of: ExposureSourceEnum
definition: Industrial facility emissions
related match: ENVO_00003861
related match: ENVO_03000092

MINING
type: Class
subclass of: ExposureSourceEnum
definition: Mining-related exposure
related match: ENVO_01001437

TRAFFIC
type: Class
subclass of: ExposureSourceEnum
definition: Traffic-related pollution
related match: ENVO_00000064
related match: ENVO_01000601

COUNTS
type: Class
subclass of: ExpressionUnitEnum
alternative label: Counts
definition: General read counts category

CPM
type: Class
subclass of: ExpressionUnitEnum
alternative label: Counts per million
definition: Counts per million reads
normalization: depth only

LOG2_RATIO
type: Class
subclass of: ExpressionUnitEnum
definition: Log2 fold change ratio
use: differential expression

NORMALIZED_COUNTS
type: Class
subclass of: ExpressionUnitEnum
alternative label: Normalized Counts
definition: Counts normalized by a method such as DESeq2 or edgeR
normalization: library size
use: differential expression

RAW_COUNTS
type: Class
subclass of: ExpressionUnitEnum
alternative label: Raw Counts
alternative label: raw counts
definition: Raw read counts of transcripts without normalization
normalization: none
use: within-sample comparisons only

RLOG
type: Class
subclass of: ExpressionUnitEnum
alternative label: rlog
definition: Regularized log transformation values
method: DESeq2
use: visualization, clustering

RPKM_UQ
type: Class
subclass of: ExpressionUnitEnum
definition: RPKM with upper quartile normalization
normalization: length, depth, and upper quartile

VST
type: Class
subclass of: ExpressionUnitEnum
definition: Variance stabilizing transformation values
method: DESeq2
use: visualization, clustering

Z_SCORE
type: Class
subclass of: ExpressionUnitEnum
definition: Z-score normalized expression
use: cross-gene comparisons

MINING_FACILITY
type: Class
title: Mining Facility
subclass of: ExtractiveIndustryFacilityTypeEnum
definition: A facility where mineral resources are extracted

QUARRY_FACILITY
type: Class
title: Quarry Facility
subclass of: ExtractiveIndustryFacilityTypeEnum
definition: A facility where stone, sand, or gravel are extracted

WELL_FACILITY
type: Class
title: Well Facility
subclass of: ExtractiveIndustryFacilityTypeEnum
definition: A facility where fluid resources are extracted

COAL
type: Class
title: Coal
subclass of: ExtractiveIndustryProductTypeEnum
definition: A combustible black or brownish-black sedimentary rock

GAS
type: Class
title: Gas
subclass of: ExtractiveIndustryProductTypeEnum
definition: A gaseous petroleum resource

GRAVEL
type: Class
title: Gravel
subclass of: ExtractiveIndustryProductTypeEnum
definition: A loose aggregation of rock fragments

METAL
type: Class
title: Metal
subclass of: ExtractiveIndustryProductTypeEnum
definition: A solid metallic substance

MINERAL
type: Class
title: Mineral
subclass of: ExtractiveIndustryProductTypeEnum
definition: A solid inorganic substance

OIL
type: Class
title: Oil
subclass of: ExtractiveIndustryProductTypeEnum
definition: A liquid petroleum resource

SAND
type: Class
title: Sand
subclass of: ExtractiveIndustryProductTypeEnum
definition: A granular material composed of finely divided rock and mineral particles

STONE
type: Class
title: Stone
subclass of: ExtractiveIndustryProductTypeEnum
definition: A solid aggregate of minerals

AIR_QUALITY_EVENT
type: Class
title: Air quality event
subclass of: ExtremeWeatherEventEnum
definition: Period of degraded air quality due to pollution accumulation, typically during temperature inversions or stagnant air conditions.
health impacts: respiratory illness, cardiovascular events
indices: AQI, PM2.5, ozone

COLD_WAVE
type: Class
title: Cold wave
subclass of: ExtremeWeatherEventEnum
definition: Prolonged period of excessively cold weather relative to the expected conditions for a given area. Associated with hypothermia and cardiovascular events.
health impacts: hypothermia, cardiovascular events, frostbite

DUST_STORM
type: Class
title: Dust storm
subclass of: ExtremeWeatherEventEnum
definition: Meteorological event with strong winds lifting large amounts of sand and dust into the atmosphere. Reduces visibility and air quality.
health impacts: respiratory illness, traffic accidents
related: haboob, sandstorm

EXTREME_PRECIPITATION
type: Class
title: Extreme precipitation
subclass of: ExtremeWeatherEventEnum
definition: Precipitation event exceeding historical norms for intensity or duration. Often precedes flooding events.
health impacts: flooding, infrastructure damage

HEAT_WAVE
type: Class
title: Heat wave
subclass of: ExtremeWeatherEventEnum
definition: Prolonged period of excessively hot weather relative to the expected conditions for a given area. Associated with increased mortality, heat stroke, and cardiovascular events.
health impacts: heat stroke, cardiovascular events, mortality
nws threshold: 2+ days of heat index >= 105F

HURRICANE
type: Class
title: Hurricane/Typhoon/Cyclone
subclass of: ExtremeWeatherEventEnum
definition: Intense tropical cyclone with sustained winds of 74 mph or greater. Called hurricane (Atlantic/E. Pacific), typhoon (W. Pacific), or cyclone (Indian Ocean).
health impacts: traumatic injuries, drowning, displacement, infectious disease
related: ENVO:01001297
saffir simpson: Category 1-5

LANDSLIDE
type: Class
title: Landslide
subclass of: ExtremeWeatherEventEnum
definition: Mass movement of rock, debris, or earth down a slope. Often triggered by extreme precipitation or earthquakes.
health impacts: traumatic injuries, burial, displacement

WINTER_STORM
type: Class
title: Winter storm
subclass of: ExtremeWeatherEventEnum
definition: Storm producing significant snow, ice, or sleet. Includes ice storms, nor'easters, and lake-effect snow events.
health impacts: injuries, hypothermia, carbon monoxide poisoning

AMBER
type: Class
subclass of: EyeColorEnum
definition: Amber/golden eyes
hex range: FFBF00-FFB300
prevalence: rare

BROWN
type: Class
subclass of: EyeColorEnum
definition: Brown eyes
hex range: 663300-8B4513
prevalence: 79% worldwide

GREEN
type: Class
subclass of: EyeColorEnum
definition: Green eyes
hex range: 2E8B57-90EE90
prevalence: 2% worldwide

HAZEL
type: Class
subclass of: EyeColorEnum
definition: Hazel eyes (brown-green mix)
hex range: 8B7355-C9A878
prevalence: 5% worldwide

RED_PINK
type: Class
subclass of: EyeColorEnum
definition: Red/pink eyes (albinism)
condition: associated with albinism

VIOLET
type: Class
subclass of: EyeColorEnum
definition: Violet eyes (extremely rare)
hex range: 8B7AB8-9370DB
prevalence: extremely rare

ACRISOLS
type: Class
subclass of: FAOSoilType
definition: Acrisols - soils with subsurface accumulation of low-activity clays and low base saturation
color rgb: 247,152,4
fao id: 1
symbol: AC

ALISOLS
type: Class
subclass of: FAOSoilType
definition: Alisols - soils with high aluminium saturation and low base saturation
color rgb: 255,255,190
fao id: 2
symbol: AL

ANTHROSOLS
type: Class
subclass of: FAOSoilType
definition: Anthrosols - soils strongly modified by human activities
color rgb: 207,152,4
fao id: 5
symbol: AT

CALCISOLS
type: Class
subclass of: FAOSoilType
definition: Calcisols - soils with secondary calcium carbonate accumulation
color rgb: 254,244,0
fao id: 7
symbol: CL

CAMBISOLS
type: Class
subclass of: FAOSoilType
definition: Cambisols - soils with beginning of horizon differentiation
color rgb: 254,190,0
fao id: 8
symbol: CM

CHERNOZEMS
type: Class
subclass of: FAOSoilType
definition: Chernozems - very dark, fertile soils with thick mollic horizon
color rgb: 145,77,53
fao id: 6
symbol: CH

FERRALSOLS
type: Class
subclass of: FAOSoilType
definition: Ferralsols - highly weathered soils with low-activity clay minerals
color rgb: 255,135,33
fao id: 11
symbol: FR

GYPSISOLS
type: Class
subclass of: FAOSoilType
definition: Gypsisols - soils with secondary gypsum accumulation
color rgb: 254,246,164
fao id: 14
symbol: GY

KASTANOZEMS
type: Class
subclass of: FAOSoilType
definition: Kastanozems - soils with chestnut-colored mollic horizon
color rgb: 202,147,127
fao id: 17
symbol: KS

LEPTOSOLS
type: Class
subclass of: FAOSoilType
definition: Leptosols - shallow soils over hard rock or highly calcareous material
color rgb: 209,209,209
fao id: 18
symbol: LP

LIXISOLS
type: Class
subclass of: FAOSoilType
definition: Lixisols - soils with clay illuviation and low base saturation
color rgb: 255,190,190
fao id: 20
symbol: LX

LUVISOLS
type: Class
subclass of: FAOSoilType
definition: Luvisols - soils with clay illuviation and high base saturation
color rgb: 250,132,132
fao id: 19
symbol: LV

NITISOLS
type: Class
subclass of: FAOSoilType
definition: Nitisols - soils with deep, well-structured clay horizons
color rgb: 255,167,127
fao id: 21
symbol: NT

NO_DATA
type: Class
subclass of: FAOSoilType
definition: No data - areas where soil data is not available
color rgb: 255,255,255
fao id: 35
symbol: ND

PHAEOZEMS
type: Class
subclass of: FAOSoilType
definition: Phaeozems - soils with dark mollic horizon and high base saturation
color rgb: 189,100,70
fao id: 22
symbol: PH

PLANOSOLS
type: Class
subclass of: FAOSoilType
definition: Planosols - soils with abrupt textural change and impermeable subsoil
color rgb: 247,125,58
fao id: 23
symbol: PL

PLINTHOSOLS
type: Class
subclass of: FAOSoilType
definition: Plinthosols - soils with iron-rich, humus-poor mixture that hardens irreversibly
color rgb: 115,0,0
fao id: 24
symbol: PT

PODZOLS
type: Class
subclass of: FAOSoilType
definition: Podzols - soils with subsurface accumulation of aluminium and iron complexes with organic matter (spodic horizon)
color rgb: 12,217,0
fao id: 25
symbol: PZ

REGOSOLS
type: Class
subclass of: FAOSoilType
definition: Regosols - weakly developed soils without significant horizon differentiation
color rgb: 254,227,164
fao id: 26
symbol: RG

RETISOLS
type: Class
subclass of: FAOSoilType
definition: Retisols - soils with clay migration and tonguing of overlying material
color rgb: 254,194,194
fao id: 27
symbol: RT

SOLONETZ
type: Class
subclass of: FAOSoilType
definition: Solonetz - soils with high exchangeable sodium content
color rgb: 249,194,254
fao id: 29
symbol: SN

STAGNOSOLS
type: Class
subclass of: FAOSoilType
definition: Stagnosols - soils with seasonal waterlogging in upper horizons
color rgb: 64,192,233
fao id: 30
symbol: ST

TECHNOSOLS
type: Class
subclass of: FAOSoilType
definition: Technosols - soils containing significant amounts of technical artifacts
color rgb: 145,0,157
fao id: 31
symbol: TC

UMBRISOLS
type: Class
subclass of: FAOSoilType
definition: Umbrisols - soils with dark acidic surface horizon
color rgb: 115,142,127
fao id: 32
symbol: UM

ACETYLATION_SITE
type: Class
subclass of: FeatureType
definition: Acetylated residue

CROSS_LINK
type: Class
subclass of: FeatureType
definition: Cross-linking site

LIPIDATION_SITE
type: Class
subclass of: FeatureType
definition: Lipid modification site

METHYLATION_SITE
type: Class
subclass of: FeatureType
definition: Methylated residue

SUMOYLATION_SITE
type: Class
subclass of: FeatureType
definition: SUMOylated residue

UBIQUITINATION_SITE
type: Class
subclass of: FeatureType
definition: Ubiquitinated residue

CORN_STEEP_LIQUOR
type: Class
subclass of: FeedstockTypeEnum
definition: Corn steep liquor
nitrogen source: true
source: Corn wet milling

LIGNOCELLULOSIC
type: Class
subclass of: FeedstockTypeEnum
definition: Lignocellulosic biomass
pretreatment: Required
source: Agricultural residues, wood

WASTE_STREAM
type: Class
subclass of: FeedstockTypeEnum
definition: Industrial waste stream
sustainability: Circular economy
variable composition: true

FED_BATCH
type: Class
subclass of: FermentationModeEnum
definition: Fed-batch fermentation
related match: MSIO_0000165
related match: MSIO_0000166
advantage: Control of growth rate
operation: Nutrients added during run

PERFUSION
type: Class
subclass of: FermentationModeEnum
definition: Perfusion culture
application: High-density cell culture
operation: Continuous media exchange with cell retention

REPEATED_BATCH
type: Class
subclass of: FermentationModeEnum
definition: Repeated batch fermentation
advantage: Reduced downtime
operation: Sequential batches with partial harvest

SEMI_CONTINUOUS
type: Class
subclass of: FermentationModeEnum
definition: Semi-continuous operation
advantage: Extended production
operation: Periodic harvest and refill

CBF
type: Class
subclass of: FileFormat
definition: Crystallographic Binary Format
applications: detector images, diffraction data
extension: .cbf

DM3
type: Class
subclass of: FileFormat
definition: Digital Micrograph format
applications: FEI/Thermo Fisher EM data
extension: .dm3, .dm4

MRC
type: Class
subclass of: FileFormat
definition: MRC format for EM density maps
applications: EM volumes, tomograms
extension: .mrc, .map

MTZ
type: Class
subclass of: FileFormat
definition: MTZ reflection data format
applications: crystallographic reflections, phases
extension: .mtz

SER
type: Class
subclass of: FileFormat
definition: FEI series format
applications: FEI movie stacks
extension: .ser

STAR
type: Class
subclass of: FileFormat
definition: Self-defining Text Archival and Retrieval format
applications: RELION metadata, particle parameters
extension: .star

YELLOW_BLACK_STRIPES
type: Class
subclass of: FireSafetyColorEnum
definition: Yellow with black stripes - fire hazard area
pattern: diagonal stripes
usage: fire hazard zones

PLUTONIUM_239
type: Class
title: Plutonium-239
subclass of: FissileIsotopeEnum
alternative label: Pu-239
definition: Fissile plutonium isotope from U-238 breeding
breeding from: U-238
half life: 24,110 years
mass number: 239
thermal fission: true

PLUTONIUM_241
type: Class
title: Plutonium-241
subclass of: FissileIsotopeEnum
alternative label: Pu-241
definition: Fissile plutonium isotope with short half-life
decay product: Am-241
half life: 14.3 years
mass number: 241
thermal fission: true

URANIUM_233
type: Class
title: Uranium-233
subclass of: FissileIsotopeEnum
alternative label: U-233
definition: Fissile isotope produced from thorium
breeding from: Th-232
half life: 159,200 years
mass number: 233
thermal fission: true

URANIUM_235
type: Class
title: Uranium-235
subclass of: FissileIsotopeEnum
alternative label: U-235
definition: Naturally occurring fissile uranium isotope
half life: 703,800,000 years
mass number: 235
natural abundance: 0.711%
thermal fission: true

BICOLOR
type: Class
subclass of: FlowerColorEnum
definition: Two-colored flowers
note: flowers with two distinct colors

BLUE
type: Class
subclass of: FlowerColorEnum
definition: Blue flowers
examples: forget-me-nots, cornflowers
hex: 0000FF

BURGUNDY
type: Class
subclass of: FlowerColorEnum
definition: Burgundy/deep red flowers
examples: dahlias, chrysanthemums
hex: 800020

CORAL
type: Class
subclass of: FlowerColorEnum
definition: Coral flowers
examples: coral bells, begonias
hex: FF7F50

CREAM
type: Class
subclass of: FlowerColorEnum
definition: Cream flowers
examples: roses, tulips
hex: FFFDD0

LAVENDER
type: Class
subclass of: FlowerColorEnum
definition: Lavender flowers
examples: lavender, wisteria
hex: E6E6FA

MAGENTA
type: Class
subclass of: FlowerColorEnum
definition: Magenta flowers
examples: fuchsias, bougainvillea
hex: FF00FF

MULTICOLOR
type: Class
subclass of: FlowerColorEnum
definition: Multi-colored flowers
note: flowers with more than two colors

ORANGE
type: Class
subclass of: FlowerColorEnum
definition: Orange flowers
examples: marigolds, zinnias
hex: FFA500

PEACH
type: Class
subclass of: FlowerColorEnum
definition: Peach flowers
examples: roses, dahlias
hex: FFDAB9

PINK
type: Class
subclass of: FlowerColorEnum
definition: Pink flowers
examples: peonies, cherry blossoms
hex: FFC0CB

PURPLE
type: Class
subclass of: FlowerColorEnum
definition: Purple flowers
examples: lavender, violets
hex: 800080

RED
type: Class
subclass of: FlowerColorEnum
definition: Red flowers
examples: roses, tulips, poppies
hex: FF0000

VIOLET
type: Class
subclass of: FlowerColorEnum
definition: Violet flowers
examples: violets, pansies
hex: 7F00FF

WHITE
type: Class
subclass of: FlowerColorEnum
definition: White flowers
examples: lilies, daisies
hex: FFFFFF

YELLOW
type: Class
subclass of: FlowerColorEnum
definition: Yellow flowers
examples: sunflowers, daffodils
hex: FFFF00

ANTHOCYANINS
type: Class
subclass of: FoodColoringEnum
definition: Anthocyanins (natural purple/red)
e number: E163
hex: 6B3AA0
source: berries, grapes

CARAMEL_COLOR
type: Class
subclass of: FoodColoringEnum
definition: Caramel coloring
e number: E150
hex: 8B4513
use: cola, sauces

FD_C_BLUE_2
type: Class
subclass of: FoodColoringEnum
definition: FD&C Blue No. 2 (Indigo Carmine)
e number: E132
hex: 4B0082
use: beverages, confections

FD_C_GREEN_3
type: Class
subclass of: FoodColoringEnum
definition: FD&C Green No. 3 (Fast Green)
e number: E143
hex: 00FF00
use: beverages, desserts

FD_C_RED_40
type: Class
subclass of: FoodColoringEnum
definition: FD&C Red No. 40 (Allura Red)
e number: E129
hex: E40000
use: beverages, candies

FD_C_YELLOW_5
type: Class
subclass of: FoodColoringEnum
definition: FD&C Yellow No. 5 (Tartrazine)
e number: E102
hex: FFFF00
use: beverages, desserts

FD_C_YELLOW_6
type: Class
subclass of: FoodColoringEnum
definition: FD&C Yellow No. 6 (Sunset Yellow)
e number: E110
hex: FFA500
use: snacks, beverages

PAPRIKA_EXTRACT
type: Class
subclass of: FoodColoringEnum
definition: Paprika extract
e number: E160c
hex: E85D00
source: paprika peppers

SPIRULINA_BLUE
type: Class
subclass of: FoodColoringEnum
definition: Spirulina extract (phycocyanin)
hex: 1E88E5
natural: true
source: spirulina algae

FraudDetectionEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Fraud Detection
status: DRAFT
subclass of: BinaryClassificationSchemaEnum
union of: NCIT C14165
union of: FRAUDULENT
definition: Fraud detection classification labels
in scheme: merged
permissible values: FRAUDULENT
permissible values: NCIT C14165
source domain: data_science
source schema: binary_classification

BPM
type: Class
subclass of: FrequencyUnitEnum
definition: Beats per minute
conversion to hz: 0.0166667
symbol: bpm
use: heart rate

GIGAHERTZ
type: Class
subclass of: FrequencyUnitEnum
definition: Gigahertz (10^9 Hz)
conversion to hz: 1e9
symbol: GHz

KILOHERTZ
type: Class
subclass of: FrequencyUnitEnum
definition: Kilohertz (1000 Hz)
conversion to hz: 1000
symbol: kHz

RPM
type: Class
subclass of: FrequencyUnitEnum
definition: Revolutions per minute
conversion to hz: 0.0166667
symbol: rpm

AGR_ASSEMBLY
type: Class
title: AGR Fuel Assembly
subclass of: FuelAssemblyTypeEnum
definition: Fuel stringer for AGR
cladding: stainless steel
geometry: stacked pins

BWR_ASSEMBLY
type: Class
title: BWR Fuel Assembly
subclass of: FuelAssemblyTypeEnum
definition: Square array fuel assembly for BWR
control method: control blades
geometry: square array with channel
rod count: 49-100 typical

CANDU_BUNDLE
type: Class
title: CANDU Fuel Bundle
subclass of: FuelAssemblyTypeEnum
definition: Cylindrical fuel bundle for PHWR
geometry: cylindrical bundle
length: ~50 cm
rod count: 28-43 typical

FAST_REACTOR_ASSEMBLY
type: Class
title: Fast Reactor Assembly
subclass of: FuelAssemblyTypeEnum
definition: Fuel assembly for fast reactors
coolant flow: axial
geometry: hexagonal wrapper

HTGR_BLOCK
type: Class
title: HTGR Fuel Block
subclass of: FuelAssemblyTypeEnum
definition: Graphite block with TRISO fuel
fuel form: TRISO particles
geometry: hexagonal or cylindrical blocks

PWR_ASSEMBLY
type: Class
title: PWR Fuel Assembly
subclass of: FuelAssemblyTypeEnum
definition: Square array fuel assembly for PWR
control method: control rod clusters
geometry: square array
rod count: 264-289 typical

RBMK_ASSEMBLY
type: Class
title: RBMK Fuel Assembly
subclass of: FuelAssemblyTypeEnum
definition: Fuel assembly for RBMK reactors
control method: control rods
geometry: 18-rod bundle
length: ~3.5 m

AQUEOUS_REPROCESSING
type: Class
title: Aqueous Reprocessing Plant
subclass of: FuelCycleFacilityTypeEnum
definition: Spent fuel reprocessing using aqueous methods
process type: PUREX or similar aqueous process
separation products: uranium, plutonium, waste
technology maturity: commercially proven

CONVENTIONAL_MINE
type: Class
title: Conventional Mine
subclass of: FuelCycleFacilityTypeEnum
definition: Traditional underground or open-pit uranium mining
extraction method: physical excavation
mine types: underground or open pit
ore grade: variable

GASEOUS_DIFFUSION_PLANT
type: Class
title: Gaseous Diffusion Enrichment Plant
subclass of: FuelCycleFacilityTypeEnum
definition: Uranium enrichment using gaseous diffusion
energy consumption: very high
enrichment method: gaseous diffusion
status: mostly retired technology

GAS_CENTRIFUGE_PLANT
type: Class
title: Gas Centrifuge Enrichment Plant
subclass of: FuelCycleFacilityTypeEnum
definition: Uranium enrichment using centrifuge technology
energy consumption: lower than diffusion
enrichment method: gas centrifuge
technology status: current standard technology

HEAP_LEACH_FACILITY
type: Class
title: Heap Leach Facility
subclass of: FuelCycleFacilityTypeEnum
definition: Uranium extraction from low-grade ores by heap leaching
economics: cost-effective for low grades
ore grade: low-grade ores
process: chemical leaching of ore piles

IN_SITU_LEACH_MINE
type: Class
title: In-Situ Leach Mine
subclass of: FuelCycleFacilityTypeEnum
definition: Uranium extraction by solution mining
environmental impact: lower surface disturbance
extraction method: chemical leaching in ground
geology requirement: permeable ore deposits

LASER_ENRICHMENT_FACILITY
type: Class
title: Laser Enrichment Facility
subclass of: FuelCycleFacilityTypeEnum
definition: Uranium enrichment using laser isotope separation
energy consumption: potentially lower
enrichment method: laser isotope separation
technology status: under development

MOX_FUEL_FABRICATION
type: Class
title: MOX Fuel Fabrication Facility
subclass of: FuelCycleFacilityTypeEnum
definition: Facility for manufacturing mixed oxide fuel
fuel type: mixed oxide (uranium and plutonium)
input materials: plutonium dioxide, uranium dioxide
special handling: plutonium handling required

PYROPROCESSING_FACILITY
type: Class
title: Pyroprocessing Facility
subclass of: FuelCycleFacilityTypeEnum
definition: Spent fuel reprocessing using electrochemical methods
process type: electrochemical separation
technology status: under development
temperature: high temperature operation

FUEL_FABRICATION
type: Class
title: Fuel Fabrication
subclass of: FuelCycleOperationEnum
definition: Manufacturing of nuclear fuel assemblies
input: enriched uranium
output: fuel assemblies
process: pellet production, rod assembly

REACTOR_FUEL_LOADING
type: Class
title: Reactor Fuel Loading
subclass of: FuelCycleOperationEnum
definition: Installation of fresh fuel in reactor
configuration: specific loading pattern
frequency: every 12-24 months
procedure: careful criticality control

REACTOR_OPERATION
type: Class
title: Reactor Operation
subclass of: FuelCycleOperationEnum
definition: Power generation and fuel burnup
burnup: fuel depletion over time
duration: 12-24 months typical cycle
output: electricity and fission products

SPENT_FUEL_DISCHARGE
type: Class
title: Spent Fuel Discharge
subclass of: FuelCycleOperationEnum
definition: Removal of used fuel from reactor
destination: spent fuel pool storage
handling: underwater fuel handling
timing: end of fuel cycle

SPENT_FUEL_REPROCESSING
type: Class
title: Spent Fuel Reprocessing
subclass of: FuelCycleOperationEnum
definition: Chemical separation of spent fuel components
recovery: recovers usable materials
separation: uranium, plutonium, waste
waste: high-level waste production

SPENT_FUEL_STORAGE
type: Class
title: Spent Fuel Storage
subclass of: FuelCycleOperationEnum
definition: Interim storage of discharged fuel
cooling: decay heat removal
duration: 5-100+ years
methods: pools, dry casks

URANIUM_CONVERSION
type: Class
title: Uranium Conversion
subclass of: FuelCycleOperationEnum
definition: Conversion of yellowcake to uranium hexafluoride
input: uranium concentrate (U3O8)
output: uranium hexafluoride (UF6)
purpose: prepare for enrichment

URANIUM_ENRICHMENT
type: Class
title: Uranium Enrichment
subclass of: FuelCycleOperationEnum
definition: Increase U-235 concentration in uranium
input: natural uranium (0.711% U-235)
methods: gas centrifuge, gaseous diffusion
output: enriched uranium (3-5% typical)
waste: depleted uranium tails

URANIUM_EXPLORATION
type: Class
title: Uranium Exploration
subclass of: FuelCycleOperationEnum
definition: Search and evaluation of uranium deposits
activities: geological surveys, drilling, sampling
methods: airborne surveys, ground exploration
purpose: locate economically viable deposits

URANIUM_EXTRACTION
type: Class
title: Uranium Extraction
subclass of: FuelCycleOperationEnum
definition: Mining and extraction of uranium ore
methods: open pit, underground, in-situ leaching
output: uranium ore
processing: crushing and grinding

URANIUM_MILLING
type: Class
title: Uranium Milling
subclass of: FuelCycleOperationEnum
definition: Processing of uranium ore to produce yellowcake
input: uranium ore
output: uranium concentrate (U3O8)
process: acid or alkaline leaching

WASTE_CONDITIONING
type: Class
title: Waste Conditioning
subclass of: FuelCycleOperationEnum
definition: Preparation of waste for storage or disposal
purpose: stable waste form
standards: waste acceptance criteria
treatment: solidification, encapsulation

WASTE_DISPOSAL
type: Class
title: Waste Disposal
subclass of: FuelCycleOperationEnum
definition: Permanent disposal of nuclear waste
isolation: long-term containment
method: geological repository
safety: protect public and environment

CONVERSION
type: Class
title: Conversion
subclass of: FuelCycleStageEnum
definition: Conversion of uranium concentrate to UF6
input: U3O8 yellowcake
output: uranium hexafluoride (UF6)

DISPOSAL
type: Class
title: Disposal
subclass of: FuelCycleStageEnum
definition: Permanent disposal of nuclear waste
duration: permanent
method: geological repository
status: under development globally

ENRICHMENT
type: Class
title: Enrichment
subclass of: FuelCycleStageEnum
definition: Increase of U-235 concentration
input: natural UF6
output: enriched UF6
waste: depleted uranium tails

FUEL_FABRICATION
type: Class
title: Fuel Fabrication
subclass of: FuelCycleStageEnum
definition: Manufacturing of fuel assemblies
input: enriched UF6
output: fuel assemblies
process: pellet and rod manufacturing

INTERIM_STORAGE
type: Class
title: Interim Storage
subclass of: FuelCycleStageEnum
definition: Temporary storage of spent fuel
duration: 5-40+ years
location: reactor pools or dry casks
purpose: cooling and decay

MINING
type: Class
title: Uranium Mining
subclass of: FuelCycleStageEnum
definition: Extraction of uranium ore from deposits
process: mining and milling
product: uranium ore concentrate (yellowcake)

REACTOR_OPERATION
type: Class
title: Reactor Operation
subclass of: FuelCycleStageEnum
definition: Power generation in nuclear reactor
duration: 12-24 months per cycle
input: fresh fuel assemblies
output: electricity and spent fuel

REPROCESSING
type: Class
title: Reprocessing
subclass of: FuelCycleStageEnum
definition: Chemical separation of spent fuel components
input: spent nuclear fuel
output: uranium, plutonium, waste
status: practiced in some countries

CERMET_FUEL
type: Class
title: Cermet Fuel
subclass of: FuelFormEnum
definition: Ceramic-metal composite fuel
structure: ceramic in metal matrix
typical use: advanced reactors

COATED_PARTICLES
type: Class
title: Coated Particles
subclass of: FuelFormEnum
definition: Microspheres with protective coatings
size: microscopic spheres
structure: TRISO or BISO coated
typical use: HTGR

DISPERSION_FUEL
type: Class
title: Dispersion Fuel
subclass of: FuelFormEnum
definition: Fuel particles dispersed in matrix
structure: particles in matrix
typical use: research reactors

LIQUID_SOLUTION
type: Class
title: Liquid Solution
subclass of: FuelFormEnum
definition: Fuel dissolved in liquid carrier
phase: liquid
typical use: molten salt reactors

METAL_SLUGS
type: Class
title: Metal Slugs
subclass of: FuelFormEnum
definition: Metallic uranium fuel elements
chemical form: metallic uranium
shape: cylindrical slugs
typical use: production reactors

OXIDE_PELLETS
type: Class
title: Oxide Pellets
subclass of: FuelFormEnum
definition: Ceramic uranium dioxide pellets
chemical form: UO2
shape: cylindrical pellets
typical use: PWR, BWR fuel rods

PLATE_FUEL
type: Class
title: Plate Fuel
subclass of: FuelFormEnum
definition: Flat plate fuel elements
geometry: flat plates
typical use: research reactors

ROD_FUEL
type: Class
title: Rod Fuel
subclass of: FuelFormEnum
definition: Cylindrical fuel rods
geometry: long cylinders
typical use: commercial power reactors

GLUON
type: Class
subclass of: FundamentalParticleType
definition: Massless gauge boson mediating the strong force between quarks

W_BOSON
type: Class
subclass of: FundamentalParticleType
definition: Massive gauge boson mediating the charged weak interaction

Z_BOSON
type: Class
subclass of: FundamentalParticleType
definition: Massive gauge boson mediating the neutral weak interaction

AWARD
type: Class
subclass of: FundingType
definition: Prize or award

CONTRACT
type: Class
subclass of: FundingType
definition: Research contract

CROWDFUNDING
type: Class
subclass of: FundingType
definition: Crowdfunded research

FOUNDATION
type: Class
subclass of: FundingType
definition: Foundation or charity funding

GIFT
type: Class
subclass of: FundingType
definition: Gift or donation

GOVERNMENT
type: Class
subclass of: FundingType
definition: Government funding

GRANT
type: Class
subclass of: FundingType
definition: Research grant

INDUSTRY
type: Class
subclass of: FundingType
definition: Industry sponsorship

INTERNAL
type: Class
subclass of: FundingType
definition: Internal/institutional funding

FIELD_REVERSED_CONFIGURATION
type: Class
subclass of: FusionConfinementType
definition: Compact toroidal confinement where the magnetic field reverses direction inside the plasma

INERTIAL_CONFINEMENT
type: Class
subclass of: FusionConfinementType
definition: Confinement by compressing fuel pellets to extreme densities using lasers or particle beams

LASER_DRIVEN
type: Class
subclass of: FusionConfinementType
definition: Fusion driven by high-power laser systems to compress and heat fuel targets

MAGNETIC_CONFINEMENT_STELLARATOR
type: Class
subclass of: FusionConfinementType
definition: Magnetic confinement using external coils to generate a twisted toroidal magnetic field (stellarator)

MAGNETIC_CONFINEMENT_TOKAMAK
type: Class
subclass of: FusionConfinementType
definition: Magnetic confinement using a toroidal chamber with an axial magnetic field and plasma current (tokamak)

MAGNETO_INERTIAL
type: Class
subclass of: FusionConfinementType
definition: Hybrid approach combining magnetic field compression with inertial confinement

SPHEROMAK
type: Class
subclass of: FusionConfinementType
definition: Compact toroidal confinement with toroidal and poloidal magnetic fields of comparable strength

Z_PINCH
type: Class
subclass of: FusionConfinementType
definition: Confinement using the magnetic field generated by a large axial current through the plasma

DEUTERIUM_DEUTERIUM
type: Class
subclass of: FusionFuelType
definition: Deuterium-deuterium (D-D) fuel, avoiding the need for scarce tritium
products: helium-3 + neutron OR tritium + proton
reactants: deuterium + deuterium

DEUTERIUM_HELIUM3
type: Class
subclass of: FusionFuelType
definition: Deuterium-helium-3 (D-He3) fuel, producing fewer neutrons than D-T
energy release: 18.3 MeV
products: helium-4 + proton
reactants: deuterium + helium-3

DEUTERIUM_TRITIUM
type: Class
subclass of: FusionFuelType
definition: Deuterium-tritium (D-T) fuel, the most studied fusion fuel with the lowest ignition temperature
energy release: 17.6 MeV
products: helium-4 + neutron
reactants: deuterium + tritium

PROTON_BORON11
type: Class
subclass of: FusionFuelType
definition: Proton-boron-11 (p-B11) aneutronic fuel producing only charged particles
energy release: 8.7 MeV
products: 3 helium-4
reactants: proton + boron-11

BETA_VALUE
type: Class
subclass of: FusionPlasmaParameterType
definition: Ratio of plasma kinetic pressure to magnetic pressure, a key performance metric

CONFINEMENT_TIME
type: Class
subclass of: FusionPlasmaParameterType
definition: Average time a particle or unit of energy remains confined in the plasma

ENERGY_GAIN_FACTOR_Q
type: Class
subclass of: FusionPlasmaParameterType
definition: Ratio of fusion power output to external heating power input (Q factor)

LAWSON_CRITERION
type: Class
subclass of: FusionPlasmaParameterType
definition: Product of plasma density and confinement time required for net energy gain

PLASMA_CURRENT
type: Class
subclass of: FusionPlasmaParameterType
definition: Electric current flowing through the plasma, important for tokamak confinement

PLASMA_DENSITY
type: Class
subclass of: FusionPlasmaParameterType
broad match: PATO_0001019
definition: Number density of particles in the plasma, measured in particles per cubic meter

PLASMA_TEMPERATURE
type: Class
subclass of: FusionPlasmaParameterType
broad match: PATO_0000146
definition: Temperature of the plasma, typically measured in electron-volts (eV) or kelvin

CONDITIONAL_KNOCKOUT
type: Class
subclass of: GeneKnockoutMethodEnum
alternative label: cKO
alternative label: floxed
definition: Conditional/inducible gene knockout (Cre-lox or similar)
mechanism: Cre-lox recombination

CONSTITUTIVE_KNOCKOUT
type: Class
subclass of: GeneKnockoutMethodEnum
alternative label: germline knockout
definition: Constitutive whole-body gene knockout

CRISPR_KNOCKOUT
type: Class
subclass of: GeneKnockoutMethodEnum
alternative label: CRISPR KO
definition: CRISPR-mediated gene knockout
mechanism: indel formation

INDUCIBLE_KNOCKOUT
type: Class
subclass of: GeneKnockoutMethodEnum
alternative label: tamoxifen-inducible
definition: Temporally inducible gene knockout
mechanism: CreERT2

TISSUE_SPECIFIC_KNOCKOUT
type: Class
subclass of: GeneKnockoutMethodEnum
definition: Tissue or cell type-specific gene knockout
mechanism: tissue-specific Cre

CRAFT
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: CRISPR Assisted mRNA Fragment Trans-splicing
definition: CRISPR Assisted mRNA Fragment Trans-splicing
mechanism: RNA trans-splicing

CRISPR_ACTIVATION
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: CRISPRa
definition: CRISPR activation (CRISPRa) for gene upregulation
effect: overexpression
mechanism: transcriptional activation

CRISPR_BASE_EDITING
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: base editing
definition: CRISPR base editing for precise nucleotide changes
mechanism: nucleotide conversion

CRISPR_INTERFERENCE
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: CRISPRi
definition: CRISPR interference (CRISPRi) for gene silencing
effect: knockdown
mechanism: transcriptional repression

CRISPR_PRIME_EDITING
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: prime editing
definition: CRISPR prime editing for versatile sequence changes
mechanism: search-and-replace

FLPE_RECOMBINASE
type: Class
subclass of: GenePerturbationMethodEnum
alternative label: Flp-FRT
definition: Flp-FRT recombination system
mechanism: site-specific recombination

TABLE_1
type: Class
subclass of: GeneticCodeTable
definition: Standard genetic code (universal)
name: Standard
ncbi id: 1

TABLE_10
type: Class
subclass of: GeneticCodeTable
definition: Euplotid nuclear code
name: Euplotid Nuclear
ncbi id: 10

TABLE_11
type: Class
subclass of: GeneticCodeTable
definition: Bacterial, archaeal and plant plastid code
name: Bacterial
ncbi id: 11

TABLE_12
type: Class
subclass of: GeneticCodeTable
definition: Alternative yeast nuclear code
name: Alternative Yeast Nuclear
ncbi id: 12

TABLE_13
type: Class
subclass of: GeneticCodeTable
definition: Ascidian mitochondrial code
name: Ascidian Mitochondrial
ncbi id: 13

TABLE_14
type: Class
subclass of: GeneticCodeTable
definition: Alternative flatworm mitochondrial code
name: Alternative Flatworm Mitochondrial
ncbi id: 14

TABLE_16
type: Class
subclass of: GeneticCodeTable
definition: Chlorophycean mitochondrial code
name: Chlorophycean Mitochondrial
ncbi id: 16

TABLE_2
type: Class
subclass of: GeneticCodeTable
definition: Vertebrate mitochondrial code
name: Vertebrate Mitochondrial
ncbi id: 2

TABLE_21
type: Class
subclass of: GeneticCodeTable
definition: Trematode mitochondrial code
name: Trematode Mitochondrial
ncbi id: 21

TABLE_22
type: Class
subclass of: GeneticCodeTable
definition: Scenedesmus obliquus mitochondrial code
name: Scenedesmus Mitochondrial
ncbi id: 22

TABLE_23
type: Class
subclass of: GeneticCodeTable
definition: Thraustochytrium mitochondrial code
name: Thraustochytrium Mitochondrial
ncbi id: 23

TABLE_24
type: Class
subclass of: GeneticCodeTable
definition: Rhabdopleuridae mitochondrial code
name: Rhabdopleuridae Mitochondrial
ncbi id: 24

TABLE_25
type: Class
subclass of: GeneticCodeTable
definition: Candidate division SR1 and gracilibacteria code
name: Candidate Division SR1
ncbi id: 25

TABLE_26
type: Class
subclass of: GeneticCodeTable
definition: Pachysolen tannophilus nuclear code
name: Pachysolen Nuclear
ncbi id: 26

TABLE_27
type: Class
subclass of: GeneticCodeTable
definition: Karyorelict nuclear code
name: Karyorelict Nuclear
ncbi id: 27

TABLE_28
type: Class
subclass of: GeneticCodeTable
definition: Condylostoma nuclear code
name: Condylostoma Nuclear
ncbi id: 28

TABLE_29
type: Class
subclass of: GeneticCodeTable
definition: Mesodinium nuclear code
name: Mesodinium Nuclear
ncbi id: 29

TABLE_3
type: Class
subclass of: GeneticCodeTable
definition: Yeast mitochondrial code
name: Yeast Mitochondrial
ncbi id: 3

TABLE_30
type: Class
subclass of: GeneticCodeTable
definition: Peritrich nuclear code
name: Peritrich Nuclear
ncbi id: 30

TABLE_31
type: Class
subclass of: GeneticCodeTable
definition: Blastocrithidia nuclear code
name: Blastocrithidia Nuclear
ncbi id: 31

TABLE_4
type: Class
subclass of: GeneticCodeTable
definition: Mold, protozoan, coelenterate mitochondrial
name: Mold Mitochondrial
ncbi id: 4

TABLE_5
type: Class
subclass of: GeneticCodeTable
definition: Invertebrate mitochondrial code
name: Invertebrate Mitochondrial
ncbi id: 5

TABLE_6
type: Class
subclass of: GeneticCodeTable
definition: Ciliate, dasycladacean, hexamita nuclear code
name: Ciliate Nuclear
ncbi id: 6

TABLE_9
type: Class
subclass of: GeneticCodeTable
definition: Echinoderm and flatworm mitochondrial code
name: Echinoderm Mitochondrial
ncbi id: 9

POLYC_TRACT
type: Class
subclass of: SO_0000001
subclass of: GenomeFeatureType
definition: A sequence of Cs

COMPOUND_HETEROZYGOUS
type: Class
subclass of: GenotypeEnum
alternative label: compound het
definition: Compound heterozygous (two different mutant alleles)

HEMIZYGOUS
type: Class
subclass of: GenotypeEnum
alternative label: -/Y
definition: Hemizygous (single allele, X-linked or deletion)

HETEROZYGOUS
type: Class
subclass of: GenotypeEnum
alternative label: +/-
alternative label: het
definition: Heterozygous for mutation or deletion

HOMOZYGOUS_MUTANT
type: Class
subclass of: GenotypeEnum
alternative label: -/-
alternative label: KO
alternative label: None
definition: Homozygous for mutation or deletion

HOMOZYGOUS_WILDTYPE
type: Class
subclass of: GenotypeEnum
alternative label: +/+
alternative label: WT
alternative label: wild-type
definition: Homozygous wild-type alleles

CENOZOIC
type: Class
subclass of: GeologicalEra
definition: Cenozoic Era (66 million years ago - present)

MESOZOIC
type: Class
subclass of: GeologicalEra
definition: Mesozoic Era (252 - 66 million years ago)

PALEOZOIC
type: Class
subclass of: GeologicalEra
definition: Paleozoic Era (541 - 252 million years ago)

PRECAMBRIAN
type: Class
subclass of: GeologicalEra
definition: Precambrian (4.6 billion - 541 million years ago)

CROSSWELL_TOMOGRAPHY
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical imaging method using sources and receivers in separate boreholes to image the intervening subsurface

DISTRIBUTED_ACOUSTIC_SENSING
type: Class
subclass of: GeophysicalMethodType
definition: A monitoring technique using fiber optic cables to measure acoustic signals along a borehole or surface deployment

DISTRIBUTED_TEMPERATURE_SENSING
type: Class
subclass of: GeophysicalMethodType
definition: A monitoring technique using fiber optic cables to measure temperature profiles along a borehole or surface deployment

ELECTRICAL_RESISTIVITY_TOMOGRAPHY
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical imaging technique that measures the electrical resistivity distribution of the subsurface

GRAVITY_SURVEY
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method measuring variations in the gravitational field to infer subsurface density distribution

GROUND_PENETRATING_RADAR
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method using radar pulses to image the shallow subsurface

MAGNETIC_SURVEY
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method measuring variations in the magnetic field to detect subsurface magnetic anomalies

MAGNETOTELLURICS
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method using natural electromagnetic fields to investigate the subsurface electrical conductivity structure

SEISMIC_REFLECTION
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method using reflected seismic waves to image subsurface geological structures

SEISMIC_REFRACTION
type: Class
subclass of: GeophysicalMethodType
definition: A geophysical method using refracted seismic waves to determine subsurface velocity structure and layer boundaries

WELL_LOGGING
type: Class
subclass of: GeophysicalMethodType
definition: Measurement of physical properties of rock formations traversed by a borehole using downhole instruments

GeospatialFormatsSchemaEnum
type: Class
subclass of: ComputingDomainEnum
definition: Schema-level enum for geospatial_formats in computing
in scheme: merged
source file: computing/geospatial_formats.yaml

ASCII_GRID
type: Class
title: Esri ASCII Grid
subclass of: GeospatialRasterFormat
definition: Simple text-based raster format. Header followed by space-delimited cell values.
extension: .asc
format: text
organization: Esri

COG
type: Class
title: Cloud Optimized GeoTIFF
subclass of: GeospatialRasterFormat
definition: GeoTIFF optimized for cloud storage with internal tiling and overviews for efficient partial reads over HTTP.
extension: .tif
features: cloud-optimized, COG
georeferencing: embedded
mime type: image/tiff

ENVI
type: Class
subclass of: GeospatialRasterFormat
definition: Format used by ENVI remote sensing software. Binary raster with separate header file.
extension: .dat, .bsq, .bil, .bip
header: .hdr

ERDAS_IMAGINE
type: Class
title: ERDAS IMAGINE
subclass of: GeospatialRasterFormat
definition: Proprietary format for ERDAS IMAGINE software. Commonly used for satellite imagery processing.
extension: .img
organization: Hexagon Geospatial

GEOTIFF
type: Class
title: GeoTIFF
subclass of: GeospatialRasterFormat
definition: TIFF image format with embedded georeferencing information. Standard format for satellite imagery and raster GIS data.
extension: .tif, .tiff
georeferencing: embedded
mime type: image/tiff
organization: OGC

GRIB
type: Class
subclass of: GeospatialRasterFormat
definition: GRIdded Binary format. Standard WMO format for meteorological data exchange.
extension: .grib, .grb, .grib2
organization: WMO
versions: GRIB1, GRIB2

HDF_EOS
type: Class
title: HDF-EOS
subclass of: GeospatialRasterFormat
definition: HDF format extended for NASA Earth Observing System data. Used for MODIS, ASTER, and other NASA satellite products.
extension: .hdf
organization: NASA
variants: HDF-EOS2, HDF-EOS5

JPEG2000
type: Class
title: JPEG 2000
subclass of: GeospatialRasterFormat
definition: Wavelet-based image compression format with georeferencing capability. Used for satellite imagery distribution.
extension: .jp2, .j2k
features: lossy/lossless compression
mime type: image/jp2

MRF
type: Class
title: Meta Raster Format
subclass of: GeospatialRasterFormat
definition: NASA format optimized for cloud storage and fast random access to large imagery datasets.
extension: .mrf
features: cloud-optimized
organization: NASA

ZARR
type: Class
title: Zarr
subclass of: GeospatialRasterFormat
definition: Chunked, compressed, N-dimensional array format designed for cloud storage. Growing adoption for climate data.
extension: .zarr (directory)
features: cloud-native, chunked
python: zarr library

FLATGEOBUF
type: Class
title: FlatGeobuf
subclass of: GeospatialVectorFormat
definition: Binary format optimized for fast streaming and random access. Cloud-native alternative to Shapefile.
extension: .fgb
features: streaming, spatial index

GEODATABASE
type: Class
title: Esri File Geodatabase
subclass of: GeospatialVectorFormat
definition: Esri proprietary format for storing multiple feature classes and tables in a folder structure.
extension: .gdb (folder)
features: multiple layers, domains, relationships
organization: Esri

GEOJSON
type: Class
title: GeoJSON
subclass of: GeospatialVectorFormat
definition: JSON-based format for encoding geographic data structures. Web-friendly and human-readable.
crs: WGS84 only
extension: .geojson, .json
mime type: application/geo+json
organization: IETF (RFC 7946)

GEOPACKAGE
type: Class
title: GeoPackage
subclass of: GeospatialVectorFormat
definition: OGC standard SQLite-based format for vector and raster data. Modern replacement for Shapefile.
extension: .gpkg
features: single file, no size limit, transactions
organization: OGC

GEOPARQUET
type: Class
title: GeoParquet
subclass of: GeospatialVectorFormat
definition: Apache Parquet with geospatial extensions. Columnar format optimized for analytics on large vector datasets.
extension: .parquet
features: columnar, cloud-optimized

GML
type: Class
subclass of: GeospatialVectorFormat
definition: Geography Markup Language. OGC XML-based format for geographic features.
extension: .gml
mime type: application/gml+xml
organization: OGC

GPKG_VECTOR
type: Class
title: GeoPackage (Vector)
subclass of: GeospatialVectorFormat
definition: Vector data stored in GeoPackage format. Can coexist with raster data in same file.
extension: .gpkg
organization: OGC

KML
type: Class
subclass of: GeospatialVectorFormat
definition: Keyhole Markup Language. XML-based format for Google Earth and other applications.
extension: .kml
mime type: application/vnd.google-earth.kml+xml
organization: OGC (originally Google)

KMZ
type: Class
subclass of: GeospatialVectorFormat
definition: Compressed KML file (ZIP archive containing KML and supporting files).
compression: ZIP
extension: .kmz
mime type: application/vnd.google-earth.kmz

SHAPEFILE
type: Class
title: Esri Shapefile
subclass of: GeospatialVectorFormat
definition: Widely used vector format consisting of multiple files (.shp, .shx, .dbf). De facto standard despite limitations.
extension: .shp (+ .shx, .dbf, .prj)
limitations: 2GB size limit, 10-char field names
organization: Esri

TOPOJSON
type: Class
title: TopoJSON
subclass of: GeospatialVectorFormat
definition: Extension of GeoJSON that encodes topology. Smaller file sizes through shared arc representation.
extension: .topojson, .json
features: topology encoding, smaller files

WKB
type: Class
title: Well-Known Binary
subclass of: GeospatialVectorFormat
definition: Binary equivalent of WKT for efficient storage and transfer.
format: binary
organization: OGC

WKT
type: Class
title: Well-Known Text
subclass of: GeospatialVectorFormat
definition: Text markup language for representing vector geometry objects.
format: text
organization: OGC
use: geometry representation

AQUACULTURE
type: Class
title: Aquaculture Heating
subclass of: GeothermalApplication
definition: Use of geothermal heat for fish farming and aquaculture.

BATHING_RECREATION
type: Class
title: Bathing and Recreation
subclass of: GeothermalApplication
definition: Use of geothermal waters for spas, pools, and recreation.

DIRECT_USE_HEATING
type: Class
title: Direct Use Heating
subclass of: GeothermalApplication
definition: Direct use of geothermal heat for space heating, district heating, or industrial processes.

ELECTRICITY_GENERATION
type: Class
title: Electricity Generation
subclass of: GeothermalApplication
definition: Use of geothermal resources for power generation through steam turbines or binary cycle plants.

FOOD_PROCESSING
type: Class
title: Food Processing
subclass of: GeothermalApplication
definition: Use of geothermal heat for food drying, pasteurization, and processing.

GREENHOUSE_HEATING
type: Class
title: Greenhouse Heating
subclass of: GeothermalApplication
definition: Use of geothermal heat for agricultural greenhouses.

INDUSTRIAL_PROCESS_HEAT
type: Class
title: Industrial Process Heat
subclass of: GeothermalApplication
definition: Use of geothermal heat for industrial manufacturing processes.

LITHIUM_EXTRACTION
type: Class
title: Lithium Extraction
subclass of: GeothermalApplication
definition: Extraction of lithium and other minerals from geothermal brines as a co-product of energy production.
co production: true

CONDUCTION_DOMINATED
type: Class
title: Conduction-Dominated Reservoir
subclass of: GeothermalReservoirType
definition: Low permeability reservoir where heat transfer is primarily through conduction rather than convection.

FAULT_CONTROLLED
type: Class
title: Fault-Controlled Reservoir
subclass of: GeothermalReservoirType
definition: Reservoir where fluid flow is controlled by fault systems providing permeability pathways.

FRACTURED_BASEMENT
type: Class
title: Fractured Basement Reservoir
subclass of: GeothermalReservoirType
alternative label: Hot Fractured Rock
definition: Reservoir in fractured crystalline basement rocks, typically granitic or metamorphic.

MAGMATIC
type: Class
title: Magmatic/Near-Magmatic Reservoir
subclass of: GeothermalReservoirType
definition: Very high temperature reservoir near or in contact with magma bodies or recent intrusions.
related match: Magma

SEDIMENTARY
type: Class
title: Sedimentary Basin Reservoir
subclass of: GeothermalReservoirType
broad match: SedimentaryBasin
definition: Reservoir in sedimentary formations with elevated temperatures due to depth or regional heat flow.

VOLCANIC
type: Class
title: Volcanic Reservoir
subclass of: GeothermalReservoirType
broad match: VolcanicField
definition: Reservoir associated with volcanic activity, typically in active volcanic regions with magma heat sources.
related match: ENVO_00000247

HIGH_TEMPERATURE
type: Class
title: High Temperature Resource
subclass of: GeothermalResourceTemperature
definition: Geothermal resource above 150C, suitable for flash steam power generation.
temperature min c: 150

LOW_TEMPERATURE
type: Class
title: Low Temperature Resource
subclass of: GeothermalResourceTemperature
definition: Geothermal resource below 90C, suitable for direct use applications.
temperature max c: 90

MODERATE_TEMPERATURE
type: Class
title: Moderate Temperature Resource
subclass of: GeothermalResourceTemperature
definition: Geothermal resource 90-150C, suitable for binary power generation.
temperature max c: 150
temperature min c: 90

SUPERCRITICAL
type: Class
title: Supercritical Resource
subclass of: GeothermalResourceTemperature
definition: Very high temperature resource above 374C where water exists in supercritical state.
temperature min c: 374

ADVANCED_GEOTHERMAL_SYSTEM
type: Class
title: Advanced Geothermal System (AGS)
subclass of: GeothermalSystemType
alternative label: AGS
alternative label: Closed-Loop Geothermal
definition: Closed-loop geothermal systems that circulate working fluid through wellbores to extract heat conductively without reservoir stimulation.
closed loop: true

ENHANCED_GEOTHERMAL_SYSTEM
type: Class
title: Enhanced Geothermal System (EGS)
subclass of: GeothermalSystemType
alternative label: EGS
alternative label: Engineered Geothermal System
definition: Engineered reservoirs created to extract heat from low permeability geothermal resources through stimulation methods.
requires stimulation: true

GEOPRESSURED
type: Class
title: Geopressured System
subclass of: GeothermalSystemType
definition: Deep sedimentary formations with abnormally high fluid pressure containing hot brine and dissolved methane.
methane recovery: true

GROUND_SOURCE_HEAT_PUMP
type: Class
title: Ground Source Heat Pump (GSHP)
subclass of: GeothermalSystemType
alternative label: GSHP
alternative label: Geothermal Heat Pump
definition: Shallow geothermal system using stable ground temperatures for heating and cooling buildings.
direct use: true

HOT_DRY_ROCK
type: Class
title: Hot Dry Rock (HDR)
subclass of: GeothermalSystemType
alternative label: HDR
definition: Geothermal system targeting hot basement rock lacking natural fluid or permeability, requiring artificial reservoir creation.

HYDROTHERMAL
type: Class
title: Conventional Hydrothermal System
subclass of: GeothermalSystemType
broad match: Geothermal
definition: Naturally occurring geothermal system with heat, fluid, and permeability sufficient for energy extraction without stimulation.
conventional: true

SUPERCRITICAL
type: Class
title: Supercritical Geothermal System
subclass of: GeothermalSystemType
definition: Very high temperature systems (>374C) where water exists above its critical point, offering higher energy density.
temperature min c: 374

DIRECTIONAL_WELL
type: Class
title: Directional/Deviated Well
subclass of: GeothermalWellType
definition: Well drilled at an angle to access reservoir from offset surface location or increase reservoir contact.

EXPLORATION_WELL
type: Class
title: Exploration Well
subclass of: GeothermalWellType
alternative label: Wildcat Well
definition: Well drilled to evaluate geothermal resource characteristics.

INJECTION_WELL
type: Class
title: Injection Well
subclass of: GeothermalWellType
alternative label: Reinjection Well
definition: Well used to return cooled geothermal fluids to the reservoir to maintain pressure and sustainability.

OBSERVATION_WELL
type: Class
title: Observation/Monitoring Well
subclass of: GeothermalWellType
alternative label: Monitoring Well
definition: Well used to monitor reservoir conditions and pressure.

PRODUCTION_WELL
type: Class
title: Production Well
subclass of: GeothermalWellType
definition: Well used to extract geothermal fluids or steam from the reservoir.

SLIM_HOLE
type: Class
title: Slim Hole
subclass of: GeothermalWellType
definition: Smaller diameter well used for initial exploration and temperature gradient measurement.

GoEvidenceSchemaEnum
type: Class
subclass of: BioDomainEnum
definition: Schema-level enum for go_evidence in bio
in scheme: merged
source file: bio/go_evidence.yaml

DIGITAL_ACCESS
type: Class
subclass of: GravitySdohDomainEnum
definition: Access to internet and digital devices

DIGITAL_LITERACY
type: Class
subclass of: GravitySdohDomainEnum
definition: Ability to use digital technology and access digital resources

FINANCIAL_INSECURITY
type: Class
subclass of: GravitySdohDomainEnum
definition: Inability to meet basic financial needs and obligations

MATERIAL_HARDSHIP
type: Class
subclass of: GravitySdohDomainEnum
definition: Difficulty affording basic necessities such as food, housing, and utilities

MEDICAL_COST_BURDEN
type: Class
subclass of: GravitySdohDomainEnum
definition: Financial strain from healthcare costs

SOCIAL_CONNECTION
type: Class
subclass of: GravitySdohDomainEnum
definition: Quality and quantity of social relationships and support networks

TRANSPORTATION_INSECURITY
type: Class
subclass of: GravitySdohDomainEnum
definition: Lack of reliable, safe, and affordable transportation

UTILITY_INSECURITY
type: Class
subclass of: GravitySdohDomainEnum
definition: Difficulty paying for utilities such as electricity, gas, or water

VETERAN_STATUS
type: Class
subclass of: GravitySdohDomainEnum
definition: Military veteran status and related needs

CAPACITOR_BANK
type: Class
subclass of: GridComponentType
definition: Array of capacitors used for reactive power compensation and voltage regulation

CIRCUIT_BREAKER
type: Class
subclass of: GridComponentType
definition: Protective device that automatically interrupts current flow during fault conditions

DISTRIBUTION_LINE
type: Class
subclass of: GridComponentType
definition: Medium- and low-voltage conductors that deliver electricity from substations to end users
related match: OEO_00410057

FACTS_DEVICE
type: Class
subclass of: GridComponentType
definition: Flexible AC Transmission System device for controlling power flow and improving grid stability

INVERTER
type: Class
subclass of: GridComponentType
definition: Device that converts direct current (DC) to alternating current (AC) for grid connection

RELAY
type: Class
subclass of: GridComponentType
definition: Protective device that detects abnormal conditions and triggers circuit breakers

SMART_METER
type: Class
subclass of: GridComponentType
definition: Advanced metering device that records energy consumption and communicates with the utility

SUBSTATION
type: Class
subclass of: GridComponentType
definition: Facility that switches, transforms, and regulates electrical power in the grid

TRANSMISSION_LINE
type: Class
subclass of: GridComponentType
definition: High-voltage conductors that carry electricity over long distances from generation to substations
related match: OEO_00410056

COMPRESSED_AIR
type: Class
title: compressed-air energy storage unit
subclass of: GridEnergyStorageType
definition: Energy storage by compressing air into underground caverns or tanks for later expansion through turbines

FLYWHEEL
type: Class
subclass of: GridEnergyStorageType
broad match: OEO_00020364
definition: Energy storage as rotational kinetic energy in a spinning mass

GRAVITY_STORAGE
type: Class
subclass of: GridEnergyStorageType
definition: Energy storage by raising heavy masses to height and lowering them to generate electricity

HYDROGEN_STORAGE
type: Class
subclass of: GridEnergyStorageType
definition: Energy storage by producing hydrogen via electrolysis for later use in fuel cells or turbines
related match: OEO_00000429

PUMPED_HYDROELECTRIC
type: Class
subclass of: GridEnergyStorageType
definition: Energy storage by pumping water to an elevated reservoir and releasing it through turbines

SUPERCAPACITOR
type: Class
subclass of: GridEnergyStorageType
definition: Electrochemical capacitor providing high power density with rapid charge and discharge cycles

THERMAL_STORAGE
type: Class
subclass of: GridEnergyStorageType
definition: Energy storage as heat in materials such as molten salt, concrete, or phase-change materials

DEMAND_RESPONSE
type: Class
subclass of: GridManagementStrategyType
definition: Adjusting consumer electricity demand in response to supply conditions or price signals

DISTRIBUTED_GENERATION
type: Class
subclass of: GridManagementStrategyType
definition: Generating electricity from many small sources close to the point of consumption

FREQUENCY_REGULATION
type: Class
subclass of: GridManagementStrategyType
definition: Maintaining grid frequency at nominal levels by balancing generation and load in real time

GRID_SCALE_STORAGE_DISPATCH
type: Class
subclass of: GridManagementStrategyType
definition: Coordinating charge and discharge of large-scale energy storage assets for grid optimization

LOAD_BALANCING
type: Class
subclass of: GridManagementStrategyType
definition: Distributing electrical load across generation sources to maintain grid stability

MICROGRID_OPERATION
type: Class
subclass of: GridManagementStrategyType
definition: Operating a localized energy grid that can function independently or connected to the main grid

PEAK_SHAVING
type: Class
subclass of: GridManagementStrategyType
definition: Reducing peak electricity demand through storage dispatch or demand reduction programs

VIRTUAL_POWER_PLANT
type: Class
subclass of: GridManagementStrategyType
definition: Aggregating distributed energy resources to operate as a single coordinated power source

VOLTAGE_CONTROL
type: Class
subclass of: GridManagementStrategyType
definition: Maintaining voltage levels within acceptable ranges across the grid

MAIN_GRID
type: Class
subclass of: GridType
definition: Main utility grid
oeo label: supply grid

MICROGRID
type: Class
subclass of: GridType
definition: Microgrid

MINI_GRID
type: Class
subclass of: GridType
definition: Mini-grid

OFF_GRID
type: Class
subclass of: GridType
definition: Off-grid/standalone

SMART_GRID
type: Class
subclass of: GridType
definition: Smart grid

VIRTUAL_POWER_PLANT
type: Class
subclass of: GridType
definition: Virtual power plant

BASEFLOW
type: Class
subclass of: GroundwaterProcessType
definition: The portion of streamflow derived from groundwater discharge into surface water bodies

BIODEGRADATION
type: Class
subclass of: GroundwaterProcessType
broad match: ENVO_06105014
definition: The biological breakdown of contaminants in groundwater by microbial activity

CONTAMINANT_TRANSPORT
type: Class
subclass of: GroundwaterProcessType
definition: The movement and spreading of dissolved or suspended contaminants through groundwater

DISCHARGE
type: Class
subclass of: GroundwaterProcessType
broad match: ENVO_01001631
definition: The process by which groundwater exits an aquifer to the surface or to another formation

LATERAL_FLOW
type: Class
subclass of: GroundwaterProcessType
broad match: ENVO_01001632
definition: Horizontal movement of groundwater through an aquifer

PRECIPITATION_DISSOLUTION
type: Class
subclass of: GroundwaterProcessType
definition: Chemical processes involving the formation or dissolution of mineral phases in groundwater

RECHARGE
type: Class
subclass of: GroundwaterProcessType
definition: The process by which water enters an aquifer from the surface or from an overlying formation

SALTWATER_INTRUSION
type: Class
subclass of: GroundwaterProcessType
definition: The movement of saline water into freshwater aquifers, typically in coastal areas

SORPTION
type: Class
subclass of: GroundwaterProcessType
definition: The process by which dissolved substances are attached to solid surfaces in the aquifer matrix

VERTICAL_LEAKAGE
type: Class
subclass of: GroundwaterProcessType
definition: Vertical movement of groundwater between aquifers through semi-confining layers

COMPENSATION_BENEFITS
type: Class
title: Compensation and Benefits
subclass of: HRFunctionEnum
definition: Managing compensation and benefits programs
activities: salary administration, benefits design
analysis: market analysis and benchmarking
competitiveness: market competitiveness
compliance: regulatory compliance
cost: cost management

EMPLOYEE_RELATIONS
type: Class
title: Employee Relations
subclass of: HRFunctionEnum
definition: Managing employee relationships and workplace issues
activities: conflict resolution, grievance handling
communication: employee communication
culture: workplace culture
focus: positive employee relations
mediation: dispute resolution

HRIS_TECHNOLOGY
type: Class
title: HRIS and Technology
subclass of: HRFunctionEnum
definition: HR information systems and technology
activities: system administration, data management
automation: process automation
integration: system integration
security: data security
systems: HRIS implementation

HR_ANALYTICS
type: Class
title: HR Analytics
subclass of: HRFunctionEnum
definition: HR data analysis and workforce metrics
activities: data analysis, metrics reporting
dashboard: HR dashboards
decision support: data-driven decisions
insights: workforce insights
predictive: predictive analytics

HR_COMPLIANCE
type: Class
title: HR Compliance
subclass of: HRFunctionEnum
definition: Employment law compliance and risk management
activities: policy development, compliance monitoring
auditing: compliance auditing
documentation: record keeping
legal: employment law compliance
risk: HR risk management

LEARNING_DEVELOPMENT
type: Class
title: Learning and Development
subclass of: HRFunctionEnum
definition: Employee training and development programs
activities: training design, skill development
career: career development
compliance: compliance training
leadership: leadership development
technology: learning management systems

ORGANIZATIONAL_DEVELOPMENT
type: Class
title: Organizational Development
subclass of: HRFunctionEnum
definition: Organizational design and change management
activities: change management, culture transformation
culture: culture development
design: organizational design
effectiveness: organizational effectiveness
transformation: business transformation

PERFORMANCE_MANAGEMENT
type: Class
title: Performance Management
subclass of: HRFunctionEnum
definition: Employee performance evaluation and improvement
activities: performance reviews, goal setting
coaching: performance coaching
development: performance improvement
feedback: continuous feedback
measurement: performance metrics

TALENT_ACQUISITION
type: Class
title: Talent Acquisition
subclass of: HRFunctionEnum
definition: Recruitment and hiring functions
activities: sourcing, screening, interviewing, hiring
focus: attracting and selecting talent
metrics: time to hire, quality of hire
strategy: workforce planning
technology: ATS and recruitment tools

AUBURN
type: Class
subclass of: HairColorEnum
definition: Auburn hair (reddish-brown)
hex: A52A2A

BLACK
type: Class
subclass of: HairColorEnum
definition: Black hair
hex: 000000
prevalence: most common worldwide

BROWN
type: Class
subclass of: HairColorEnum
definition: Brown hair
hex range: 654321-8B4513

DARK_BLONDE
type: Class
subclass of: HairColorEnum
definition: Dark blonde hair
hex: 9F8F71

DARK_BROWN
type: Class
subclass of: HairColorEnum
definition: Dark brown hair
hex: 3B2F2F

GINGER
type: Class
subclass of: HairColorEnum
definition: Ginger hair (orange-red)
hex: FF6600

LIGHT_BLONDE
type: Class
subclass of: HairColorEnum
definition: Light blonde hair
hex: FFF8DC

LIGHT_BROWN
type: Class
subclass of: HairColorEnum
definition: Light brown hair
hex: 977961

PLATINUM_BLONDE
type: Class
subclass of: HairColorEnum
definition: Platinum blonde hair
hex: E5E5E5

SILVER
type: Class
subclass of: HairColorEnum
definition: Silver hair
hex: C0C0C0

STRAWBERRY_BLONDE
type: Class
subclass of: HairColorEnum
definition: Strawberry blonde hair
hex: FF9966

BORDERLINE
type: Class
subclass of: HardOrSoftEnum
definition: Borderline acids/bases
examples: Fe2+, Co2+, Ni2+, Cu2+, Zn2+
polarizability: intermediate

HARD
type: Class
subclass of: HardOrSoftEnum
definition: Hard acids/bases (small, high charge density)
examples: H+, Li+, Mg2+, Al3+, F-, OH-
polarizability: low

SOFT
type: Class
subclass of: HardOrSoftEnum
definition: Soft acids/bases (large, low charge density)
examples: Cu+, Ag+, Au+, I-, S2-
polarizability: high

BLACK_WHITE_STRIPES
type: Class
subclass of: HazmatColorEnum
definition: Black and white stripes - corrosive (Class 8)
class: 8
hazard: corrosive substances
pattern: black and white vertical stripes

WHITE_RED_STRIPES
type: Class
subclass of: HazmatColorEnum
definition: White with red stripes - flammable solid (Class 4.1)
class: 4.1
hazard: flammable solid
pattern: white with red vertical stripes

Ambulance Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person using transportation service for the purpose of initiating one of the other Visits, without a Care Site, within one day, potentially with Providers accompanying the Visit and delivering service

Case Management Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person interacting with healthcare system, without a Care Site, within a day, with no Providers involved, for administrative purposes

Emergency Room Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting dedicated healthcare institution for treating emergencies, at a Care Site, within one day, with physicians and Providers permanently available to deliver service around the clock

Emergency Room and Inpatient Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting ER followed by a subsequent Inpatient Visit, where Emergency department is part of hospital, and transition from the ER to other hospital departments is undefined

Home Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Provider visiting Person, without a Care Site, within one day, delivering service

Inpatient Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting hospital, at a Care Site, in bed, for duration of more than one day, with physicians and other Providers permanently available to deliver service around the clock

Laboratory Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Patient visiting dedicated institution, at a Care Site, within one day, for the purpose of a Measurement.

Non-hospital institution Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting dedicated institution for reasons of poor health, at a Care Site, long-term or permanently, with no physician but possibly other Providers permanently available to deliver service around the clock

Outpatient Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting dedicated ambulatory healthcare institution, at a Care Site, within one day, without bed, with physicians or medical Providers delivering service during Visit

Pharmacy Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Person visiting pharmacy for dispensing of Drug, at a Care Site, within one day

Telehealth Visit
type: Class
subclass of: HealthcareEncounterClassification
definition: Patient engages with Provider through communication media

ANCIENT
type: Class
subclass of: HistoricalPeriod
definition: Ancient history (3000 BCE - 500 CE)

CLASSICAL_ANTIQUITY
type: Class
subclass of: HistoricalPeriod
definition: Classical antiquity (8th century BCE - 6th century CE)

CONTEMPORARY
type: Class
subclass of: HistoricalPeriod
definition: Contemporary period (mid 20th century - present)

DIGITAL_AGE
type: Class
subclass of: HistoricalPeriod
definition: Digital/Information age (1950s - present)

EARLY_MODERN
type: Class
subclass of: HistoricalPeriod
definition: Early modern period (15th - 18th century)

INDUSTRIAL_AGE
type: Class
subclass of: HistoricalPeriod
definition: Industrial age (1760 - 1840)

MIDDLE_AGES
type: Class
subclass of: HistoricalPeriod
definition: Middle Ages (5th - 15th century)

MODERN
type: Class
subclass of: HistoricalPeriod
definition: Modern era (19th century - mid 20th century)

PREHISTORIC
type: Class
subclass of: HistoricalPeriod
definition: Before written records

RENAISSANCE
type: Class
subclass of: HistoricalPeriod
definition: Renaissance (14th - 17th century)

ABSENT
type: Class
subclass of: HistoricalStatusEnum
definition: Currently absent in the patient

HISTORICAL
type: Class
subclass of: HistoricalStatusEnum
definition: Was present in the patient historically but not currently

PRESENT
type: Class
subclass of: HistoricalStatusEnum
definition: Currently present in the patient

UNKNOWN
type: Class
subclass of: HistoricalStatusEnum
definition: Current status is unknown

AMMONIA_SYNTHESIS
type: Class
title: Ammonia Synthesis
subclass of: HydrogenApplication
definition: Use of hydrogen with nitrogen to produce ammonia for fertilizers.
related match: Ammonia

BLENDING_NATURAL_GAS
type: Class
title: Natural Gas Blending
subclass of: HydrogenApplication
definition: Blending hydrogen into natural gas pipelines for decarbonization of heating.

FUEL_CELL_STATIONARY
type: Class
title: Stationary Fuel Cell
subclass of: HydrogenApplication
definition: Use of hydrogen in stationary fuel cells for power generation.

FUEL_CELL_VEHICLE
type: Class
title: Fuel Cell Electric Vehicle
subclass of: HydrogenApplication
alternative label: FCEV
definition: Use of hydrogen in fuel cells for transportation (cars, trucks, buses).

INDUSTRIAL_FEEDSTOCK
type: Class
title: Industrial Feedstock
subclass of: HydrogenApplication
definition: Use of hydrogen as chemical feedstock for ammonia production, petroleum refining, and chemical synthesis.

METHANOL_SYNTHESIS
type: Class
title: Methanol Synthesis
subclass of: HydrogenApplication
definition: Use of hydrogen with CO2 to produce methanol.
related match: Methanol

POWER_TO_GAS
type: Class
title: Power-to-Gas
subclass of: HydrogenApplication
alternative label: P2G
definition: Conversion of excess renewable electricity to hydrogen for grid balancing and energy storage.

STEEL_PRODUCTION
type: Class
title: Steel Production (Direct Reduction)
subclass of: HydrogenApplication
alternative label: Green Steel
definition: Use of hydrogen to reduce iron ore in steelmaking, replacing coal.

SYNTHETIC_FUELS
type: Class
title: Synthetic Fuel Production
subclass of: HydrogenApplication
alternative label: E-Fuels
alternative label: Power-to-Liquid
definition: Use of hydrogen with captured CO2 to produce synthetic hydrocarbons (e-fuels, SAF).

ALKALINE_ELECTROLYSIS
type: Class
title: Alkaline Electrolysis (AEL)
subclass of: HydrogenProductionMethod
alternative label: AEL
definition: Electrolysis using alkaline solution (typically KOH) as electrolyte. Mature commercial technology.
electrolyte: alkaline
maturity: commercial

AUTOTHERMAL_REFORMING
type: Class
title: Autothermal Reforming (ATR)
subclass of: HydrogenProductionMethod
alternative label: ATR
definition: Combines steam reforming and partial oxidation using oxygen and steam to produce hydrogen from hydrocarbons.

BIOLOGICAL_PRODUCTION
type: Class
title: Biological Hydrogen Production
subclass of: HydrogenProductionMethod
alternative label: Biohydrogen
definition: Production of hydrogen by microorganisms through photosynthesis, fermentation, or other biological processes.
maturity: research
renewable: true

BIOMASS_GASIFICATION
type: Class
title: Biomass Gasification
subclass of: HydrogenProductionMethod
definition: Thermochemical conversion of biomass to hydrogen-rich syngas at high temperatures.
narrow match: Gasification
feedstock: biomass
renewable: true

METHANE_PYROLYSIS
type: Class
title: Methane Pyrolysis
subclass of: HydrogenProductionMethod
alternative label: Thermal Cracking
definition: Thermal decomposition of methane into hydrogen and solid carbon without oxygen. Produces no direct CO2.
byproduct: solid_carbon
feedstock: natural_gas

PARTIAL_OXIDATION
type: Class
title: Partial Oxidation (POX)
subclass of: HydrogenProductionMethod
alternative label: POX
definition: Exothermic process reacting hydrocarbons with limited oxygen to produce hydrogen and carbon monoxide.

PEM_ELECTROLYSIS
type: Class
title: PEM Electrolysis
subclass of: HydrogenProductionMethod
alternative label: PEMEC
alternative label: Polymer Electrolyte Membrane Electrolysis
definition: Proton Exchange Membrane electrolysis using solid polymer electrolyte. Higher efficiency, faster response.
electrolyte: polymer_membrane
maturity: commercial

PHOTOELECTROCHEMICAL
type: Class
title: Photoelectrochemical Water Splitting
subclass of: HydrogenProductionMethod
alternative label: PEC
definition: Direct conversion of sunlight to hydrogen using specialized semiconductor materials in contact with water.
maturity: research

SOLID_OXIDE_ELECTROLYSIS
type: Class
title: Solid Oxide Electrolysis (SOEC)
subclass of: HydrogenProductionMethod
alternative label: SOEC
definition: High temperature electrolysis using solid ceramic electrolyte. Higher efficiency when waste heat is available.
electrolyte: solid_oxide
maturity: emerging
temperature c: 700-850

STEAM_METHANE_REFORMING
type: Class
title: Steam Methane Reforming (SMR)
subclass of: HydrogenProductionMethod
alternative label: SMR
definition: High temperature steam reacts with methane to produce hydrogen, carbon monoxide, and carbon dioxide.
dominant method: true
feedstock: natural_gas
temperature c: 700-1000

THERMOCHEMICAL_WATER_SPLITTING
type: Class
title: Thermochemical Water Splitting
subclass of: HydrogenProductionMethod
definition: Using high temperatures from concentrated solar or nuclear to drive chemical cycles that split water.
maturity: research
temperature c: 500-2000

WATER_ELECTROLYSIS
type: Class
title: Water Electrolysis
subclass of: HydrogenProductionMethod
alternative label: Electrolysis
definition: Splitting water into hydrogen and oxygen using electrical current. Can be powered by various energy sources.

CHEMICAL_HYDRIDE
type: Class
title: Chemical Hydride Storage
subclass of: HydrogenStorageMethod
alternative label: LOHC
alternative label: Liquid Organic Hydrogen Carrier
definition: Storage as chemical compounds (ammonia, methanol, LOHC) that release hydrogen when processed.

COMPRESSED_GAS
type: Class
title: Compressed Gas Storage
subclass of: HydrogenStorageMethod
alternative label: CGH2
definition: Storage of hydrogen as compressed gas at high pressure (350-700 bar) in pressure vessels.
maturity: commercial
pressure bar: 350-700

CRYO_COMPRESSED
type: Class
title: Cryo-Compressed Storage
subclass of: HydrogenStorageMethod
alternative label: CcH2
definition: Hybrid approach combining cryogenic cooling with high pressure for improved density.
maturity: emerging

LIQUID_HYDROGEN
type: Class
title: Liquid Hydrogen Storage
subclass of: HydrogenStorageMethod
alternative label: LH2
definition: Storage of hydrogen in liquid form at cryogenic temperatures (-253C). Higher energy density but requires insulation.
maturity: commercial
temperature c: -253

METAL_HYDRIDE
type: Class
title: Metal Hydride Storage
subclass of: HydrogenStorageMethod
definition: Storage of hydrogen absorbed into metal alloys forming metal hydrides. Safer but heavier than compressed gas.
maturity: commercial

UNDERGROUND_STORAGE
type: Class
title: Underground Storage
subclass of: HydrogenStorageMethod
alternative label: Geological Storage
definition: Large-scale storage in salt caverns, depleted gas fields, or aquifers for grid-scale applications.
scale: utility

BLACK_HYDROGEN
type: Class
title: Black Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced from black coal (bituminous) gasification without carbon capture. High carbon intensity.
carbon intensity: very_high
energy source: bituminous_coal
production method: coal_gasification

BLUE_HYDROGEN
type: Class
title: Blue Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced from natural gas via steam methane reforming (SMR) with carbon capture and storage (CCS). Low carbon intensity.
carbon intensity: low
energy source: natural_gas
production method: steam_methane_reforming
requires ccs: true

BROWN_HYDROGEN
type: Class
title: Brown Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced from brown coal (lignite) gasification without carbon capture. High carbon intensity.
carbon intensity: very_high
energy source: lignite
production method: coal_gasification

GREEN_HYDROGEN
type: Class
title: Green Hydrogen
subclass of: HydrogenType
alternative label: Renewable Hydrogen
broad match: Hydrogen
definition: Hydrogen produced via electrolysis powered by renewable energy sources (solar, wind, hydro). Zero carbon emissions during production.
carbon intensity: zero
energy source: renewable
production method: electrolysis

GREY_HYDROGEN
type: Class
title: Grey Hydrogen
subclass of: HydrogenType
alternative label: Gray Hydrogen
definition: Hydrogen produced from natural gas via steam methane reforming without carbon capture. Most common production method currently.
carbon intensity: high
co2 per kg h2: 9-12
energy source: natural_gas
production method: steam_methane_reforming

ORANGE_HYDROGEN
type: Class
title: Orange Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced from plastic waste gasification or pyrolysis. Emerging technology addressing both energy and waste challenges.
carbon intensity: varies
energy source: plastic_waste
production method: waste_gasification

PINK_HYDROGEN
type: Class
title: Pink Hydrogen
subclass of: HydrogenType
alternative label: Purple Hydrogen
alternative label: Red Hydrogen
definition: Hydrogen produced via electrolysis powered by nuclear energy. Zero carbon emissions during production.
carbon intensity: zero
energy source: nuclear
production method: electrolysis

TURQUOISE_HYDROGEN
type: Class
title: Turquoise Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced via methane pyrolysis, producing solid carbon instead of CO2. Lower carbon intensity than grey hydrogen.
byproduct: solid_carbon
carbon intensity: low
energy source: natural_gas
production method: methane_pyrolysis

WHITE_HYDROGEN
type: Class
title: White Hydrogen
subclass of: HydrogenType
alternative label: Geological Hydrogen
alternative label: Gold Hydrogen
alternative label: Natural Hydrogen
definition: Naturally occurring geological hydrogen found in underground deposits. Zero production emissions.
carbon intensity: zero
energy source: natural
production method: geological_extraction

YELLOW_HYDROGEN
type: Class
title: Yellow Hydrogen
subclass of: HydrogenType
definition: Hydrogen produced via electrolysis powered by solar energy specifically. A subset of green hydrogen.
carbon intensity: zero
energy source: solar
production method: electrolysis

EXTRACTION_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to remove contaminated groundwater as part of remediation activities

GEOTHERMAL_WELL
type: Class
subclass of: HydrogeologyWellType
broad match: ENVO_01000002
definition: A well drilled to access geothermal resources for energy production or direct use

INJECTION_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to inject fluids into the subsurface for disposal, storage, or aquifer recharge

MONITORING_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to observe and measure groundwater conditions such as water level, quality, and flow

OBSERVATION_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to observe hydrological parameters without significant water extraction

PIEZOMETER
type: Class
subclass of: HydrogeologyWellType
definition: A device or small-diameter well used to measure hydraulic head at a specific point in the subsurface

PRODUCTION_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to extract groundwater for water supply purposes

RECHARGE_WELL
type: Class
subclass of: HydrogeologyWellType
definition: A well used to artificially replenish groundwater by injecting treated water into an aquifer

EXEMPT_WASTE
type: Class
title: Exempt Waste (EW)
subclass of: IAEAWasteClassificationEnum
alternative label: EW
definition: Waste with negligible radioactivity requiring no regulatory control
activity level: negligible
clearance: can be cleared from regulatory control
disposal: as ordinary waste
regulatory control: none required

HIGH_LEVEL_WASTE
type: Class
title: High Level Waste (HLW)
subclass of: IAEAWasteClassificationEnum
alternative label: HLW
definition: Waste requiring containment for thousands to hundreds of thousands of years
activity level: high
containment period: thousands to hundreds of thousands of years
cooling: required
disposal: geological disposal
heat generation: significant (>2 kW/m³)
shielding: heavy shielding required

INTERMEDIATE_LEVEL_WASTE
type: Class
title: Intermediate Level Waste (ILW)
subclass of: IAEAWasteClassificationEnum
alternative label: ILW
definition: Waste requiring containment for thousands of years
activity level: intermediate
containment period: up to thousands of years
disposal: geological disposal
heat generation: low (<2 kW/m³)
shielding: required

LOW_LEVEL_WASTE
type: Class
title: Low Level Waste (LLW)
subclass of: IAEAWasteClassificationEnum
alternative label: LLW
definition: Waste requiring containment for up to hundreds of years
activity level: low
containment period: up to few hundred years
disposal: near-surface disposal
heat generation: negligible

VERY_LOW_LEVEL_WASTE
type: Class
title: Very Low Level Waste (VLLW)
subclass of: IAEAWasteClassificationEnum
alternative label: VLLW
definition: Waste requiring limited containment and isolation
activity level: very low but above exempt
containment requirement: limited
disposal: near-surface landfill-type
isolation period: limited

VERY_SHORT_LIVED_WASTE
type: Class
title: Very Short-Lived Waste (VSLW)
subclass of: IAEAWasteClassificationEnum
alternative label: VSLW
definition: Waste stored for decay to exempt levels within few years
clearance: after decay period
decay strategy: storage for decay
storage period: up to few years
typical sources: medical, research isotopes

GROUP_1
type: Class
title: Carcinogenic to humans
subclass of: IARCCarcinogenicityGroup
definition: Sufficient evidence of carcinogenicity in humans. The agent is carcinogenic to humans.
evidence level: sufficient in humans
examples: asbestos, benzene, tobacco smoking, ionizing radiation

GROUP_2A
type: Class
title: Probably carcinogenic to humans
subclass of: IARCCarcinogenicityGroup
definition: Limited evidence of carcinogenicity in humans and sufficient evidence in experimental animals. The agent is probably carcinogenic to humans.
evidence level: limited in humans, sufficient in animals
examples: red meat, night shift work, glyphosate

GROUP_2B
type: Class
title: Possibly carcinogenic to humans
subclass of: IARCCarcinogenicityGroup
definition: Limited evidence of carcinogenicity in humans and less than sufficient evidence in experimental animals. The agent is possibly carcinogenic to humans.
evidence level: limited in humans or animals
examples: coffee, pickled vegetables, gasoline engine exhaust

GROUP_3
type: Class
title: Not classifiable as to carcinogenicity
subclass of: IARCCarcinogenicityGroup
definition: Inadequate evidence of carcinogenicity in humans and inadequate or limited evidence in experimental animals. The agent is not classifiable as to its carcinogenicity to humans.
evidence level: inadequate
examples: caffeine, cholesterol, saccharin

LEVEL_0
type: Class
title: Level 0 - Below Scale/Deviation
subclass of: INESLevelEnum
definition: Events without safety significance
examples: minor technical issues
public impact: none
safety significance: no safety significance
scale position: below scale

LEVEL_1
type: Class
title: Level 1 - Anomaly
subclass of: INESLevelEnum
definition: Anomaly beyond authorized operating regime
examples: minor contamination, minor safety system failure
public impact: none
safety significance: minor
scale position: incidents

LEVEL_2
type: Class
title: Level 2 - Incident
subclass of: INESLevelEnum
definition: Incident with significant defenses remaining
public impact: none
radiation dose: <10 mSv to workers
safety significance: minor
scale position: incidents

LEVEL_3
type: Class
title: Level 3 - Serious Incident
subclass of: INESLevelEnum
definition: Serious incident with some defense degradation
examples: near accident, serious contamination
public impact: very minor
radiation dose: <100 mSv to workers
safety significance: minor
scale position: incidents

LEVEL_4
type: Class
title: Level 4 - Accident with Local Consequences
subclass of: INESLevelEnum
definition: Accident with minor off-site releases
evacuation: not required
examples: partial core damage
public impact: minor local impact
safety significance: moderate
scale position: accidents

LEVEL_5
type: Class
title: Level 5 - Accident with Wider Consequences
subclass of: INESLevelEnum
definition: Accident with limited off-site releases
examples: Three Mile Island (1979)
protective actions: limited evacuation
public impact: limited wider impact
safety significance: moderate to major
scale position: accidents

LEVEL_6
type: Class
title: Level 6 - Serious Accident
subclass of: INESLevelEnum
definition: Serious accident with significant releases
protective actions: extensive evacuation and countermeasures
public impact: significant
safety significance: major
scale position: accidents

LEVEL_7
type: Class
title: Level 7 - Major Accident
subclass of: INESLevelEnum
definition: Major accident with widespread health and environmental effects
consequences: long-term environmental contamination
examples: Chernobyl (1986), Fukushima (2011)
public impact: widespread
safety significance: major
scale position: accidents

HIGH_CONFIDENCE
type: Class
subclass of: IPCCConfidenceLevel
definition: High confidence in the validity of a finding.

LOW_CONFIDENCE
type: Class
subclass of: IPCCConfidenceLevel
definition: Low confidence in the validity of a finding.

MEDIUM_CONFIDENCE
type: Class
subclass of: IPCCConfidenceLevel
definition: Medium confidence in the validity of a finding.

VERY_HIGH_CONFIDENCE
type: Class
subclass of: IPCCConfidenceLevel
definition: Very high confidence in the validity of a finding.

VERY_LOW_CONFIDENCE
type: Class
subclass of: IPCCConfidenceLevel
definition: Very low confidence in the validity of a finding.

ABOUT_AS_LIKELY_AS_NOT
type: Class
subclass of: IPCCLikelihoodScale
definition: 33-66% probability of occurrence/truth.
probability range: 0.33-0.66

EXCEPTIONALLY_UNLIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 0-1% probability of occurrence/truth.
probability range: 0.00-0.01

EXTREMELY_LIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 95-100% probability of occurrence/truth.
probability range: 0.95-1.00

EXTREMELY_UNLIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 0-5% probability of occurrence/truth.
probability range: 0.00-0.05

LIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 66-100% probability of occurrence/truth.
probability range: 0.66-1.00

MORE_LIKELY_THAN_NOT
type: Class
subclass of: IPCCLikelihoodScale
definition: Greater than 50% to 100% probability of occurrence/truth.
probability range: 0.50-1.00

UNLIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 0-33% probability of occurrence/truth.
probability range: 0.00-0.33

VERY_LIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 90-100% probability of occurrence/truth.
probability range: 0.90-1.00

VERY_UNLIKELY
type: Class
subclass of: IPCCLikelihoodScale
definition: 0-10% probability of occurrence/truth.
probability range: 0.00-0.10

VIRTUALLY_CERTAIN
type: Class
subclass of: IPCCLikelihoodScale
definition: 99-100% probability of occurrence/truth.
probability range: 0.99-1.00

A
type: Class
subclass of: IUPACAminoAcidCode
definition: Alanine

B
type: Class
subclass of: IUPACAminoAcidCode
definition: Asparagine or Aspartic acid (N or D)

C
type: Class
subclass of: IUPACAminoAcidCode
definition: Cysteine

D
type: Class
subclass of: IUPACAminoAcidCode
definition: Aspartic acid

E
type: Class
subclass of: IUPACAminoAcidCode
definition: Glutamic acid

F
type: Class
subclass of: IUPACAminoAcidCode
definition: Phenylalanine

G
type: Class
subclass of: IUPACAminoAcidCode
definition: Glycine

GAP
type: Class
title: -
subclass of: IUPACAminoAcidCode
definition: Gap or deletion in alignment

H
type: Class
subclass of: IUPACAminoAcidCode
definition: Histidine

I
type: Class
subclass of: IUPACAminoAcidCode
definition: Isoleucine

J
type: Class
subclass of: IUPACAminoAcidCode
definition: Leucine or Isoleucine (L or I)

K
type: Class
subclass of: IUPACAminoAcidCode
definition: Lysine

L
type: Class
subclass of: IUPACAminoAcidCode
definition: Leucine

M
type: Class
subclass of: IUPACAminoAcidCode
definition: Methionine

N
type: Class
subclass of: IUPACAminoAcidCode
definition: Asparagine

O
type: Class
subclass of: IUPACAminoAcidCode
alternative label: Pyl
definition: Pyrrolysine (22nd amino acid)

P
type: Class
subclass of: IUPACAminoAcidCode
definition: Proline

Q
type: Class
subclass of: IUPACAminoAcidCode
definition: Glutamine

R
type: Class
subclass of: IUPACAminoAcidCode
definition: Arginine

S
type: Class
subclass of: IUPACAminoAcidCode
definition: Serine

STOP
type: Class
title: *
subclass of: IUPACAminoAcidCode
definition: Translation stop codon

T
type: Class
subclass of: IUPACAminoAcidCode
definition: Threonine

U
type: Class
subclass of: IUPACAminoAcidCode
alternative label: Sec
definition: Selenocysteine (21st amino acid)

V
type: Class
subclass of: IUPACAminoAcidCode
definition: Valine

W
type: Class
subclass of: IUPACAminoAcidCode
definition: Tryptophan

X
type: Class
subclass of: IUPACAminoAcidCode
definition: Any amino acid

Y
type: Class
subclass of: IUPACAminoAcidCode
definition: Tyrosine

Z
type: Class
subclass of: IUPACAminoAcidCode
definition: Glutamine or Glutamic acid (Q or E)

A
type: Class
subclass of: IUPACNucleotideCode
definition: Adenine

B
type: Class
subclass of: IUPACNucleotideCode
definition: Not A (C or G or T/U)

C
type: Class
subclass of: IUPACNucleotideCode
definition: Cytosine

D
type: Class
subclass of: IUPACNucleotideCode
definition: Not C (A or G or T/U)

G
type: Class
subclass of: IUPACNucleotideCode
definition: Guanine

GAP
type: Class
title: -
subclass of: IUPACNucleotideCode
definition: Gap or deletion in alignment

H
type: Class
subclass of: IUPACNucleotideCode
definition: Not G (A or C or T/U)

K
type: Class
subclass of: IUPACNucleotideCode
definition: Keto (G or T/U)

M
type: Class
subclass of: IUPACNucleotideCode
definition: Amino (A or C)

N
type: Class
subclass of: IUPACNucleotideCode
definition: Any nucleotide (A or C or G or T/U)

R
type: Class
subclass of: IUPACNucleotideCode
definition: Purine (A or G)

S
type: Class
subclass of: IUPACNucleotideCode
definition: Strong interaction (G or C)

T
type: Class
subclass of: IUPACNucleotideCode
definition: Thymine (DNA)

U
type: Class
subclass of: IUPACNucleotideCode
definition: Uracil (RNA)

V
type: Class
subclass of: IUPACNucleotideCode
definition: Not T/U (A or C or G)

W
type: Class
subclass of: IUPACNucleotideCode
definition: Weak interaction (A or T/U)

Y
type: Class
subclass of: IUPACNucleotideCode
definition: Pyrimidine (C or T/U)

Iccc3SchemaEnum
type: Class
subclass of: MedicalDomainEnum
definition: Schema-level enum for iccc3 in medical
in scheme: merged
source file: medical/pediatric_oncology/iccc3.yaml

ABDOMEN_PELVIS_ENCASING_AORTA_IVC
type: Class
title: Abdomen/pelvis - Tumor encasing aorta and/or IVC
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing aorta and/or inferior vena cava.

ABDOMEN_PELVIS_ENCASING_CELIAC_SMA
type: Class
title: Abdomen/pelvis - Tumor encasing celiac axis and/or SMA
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing celiac axis and/or superior mesenteric artery.

ABDOMEN_PELVIS_ENCASING_ILIAC_VESSELS
type: Class
title: Abdomen/pelvis - Tumor encasing iliac vessels
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing iliac vessels.

ABDOMEN_PELVIS_ENCASING_RENAL_VESSELS
type: Class
title: Abdomen/pelvis - Tumor encasing origin of renal vessels
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing origin of renal vessels.

ABDOMEN_PELVIS_PELVIC_CROSSING_SCIATIC_NOTCH
type: Class
title: Abdomen/pelvis - Pelvic tumor crossing sciatic notch
subclass of: ImageDefinedRiskFactor
definition: Pelvic tumor crossing the sciatic notch.

ADJACENT_ORGAN_INFILTRATION
type: Class
title: Infiltration of adjacent organs/structures
subclass of: ImageDefinedRiskFactor
definition: Infiltration of adjacent organs/structures such as pericardium, diaphragm, kidney, liver, duodeno-pancreatic block, and mesentery.

CERVICOTHORACIC_COMPRESSING_TRACHEA
type: Class
title: Cervico-thoracic junction - Tumor compressing trachea
subclass of: ImageDefinedRiskFactor
definition: Tumor compressing the trachea.

CERVICOTHORACIC_ENCASING_BRACHIAL_PLEXUS
type: Class
title: Cervico-thoracic junction - Tumor encasing brachial plexus roots
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing brachial plexus roots (C5-T1).

CERVICOTHORACIC_ENCASING_SUBCLAVIAN
type: Class
title: Cervico-thoracic junction - Tumor encasing subclavian vessels
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing subclavian vessels and/or vertebral artery and/or carotid artery.

INTRASPINAL_EXTENSION
type: Class
title: Intraspinal tumor extension
subclass of: ImageDefinedRiskFactor
definition: Intraspinal tumor extension provided that more than one third of the spinal canal in the axial plane is invaded and/or the perimedullary leptomeningeal spaces are not visible and/or spinal cord signal is abnormal.

IPSILATERAL_TUMOR_EXTENSION_TO_BODY_CAVITIES
type: Class
title: Ipsilateral tumor extension within two body compartments
subclass of: ImageDefinedRiskFactor
definition: Tumor extension from neck to chest, chest to abdomen, or abdomen to pelvis.

NECK_COMPRESSING_TRACHEA
type: Class
title: Neck - Tumor compressing trachea
subclass of: ImageDefinedRiskFactor
definition: Tumor compressing the trachea.

NECK_ENCASING_CAROTID_OR_VERTEBRAL
type: Class
title: Neck - Tumor encasing carotid and/or vertebral artery
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing carotid artery and/or vertebral artery.

NECK_ENCASING_JUGULAR
type: Class
title: Neck - Tumor encasing internal jugular vein
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing internal jugular vein.

NECK_EXTENDING_TO_SKULL_BASE
type: Class
title: Neck - Tumor extending to base of skull
subclass of: ImageDefinedRiskFactor
definition: Tumor extending to base of skull.

THORACOABDOMINAL_ENCASING_AORTA_CELIAC
type: Class
title: Thoraco-abdominal - Tumor encasing aorta and/or vena cava
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing the aorta and/or vena cava.

THORAX_COMPRESSING_TRACHEA_BRONCHI
type: Class
title: Thorax - Tumor compressing trachea and/or principal bronchi
subclass of: ImageDefinedRiskFactor
definition: Tumor compressing trachea and/or principal bronchi.

THORAX_ENCASING_AORTA
type: Class
title: Thorax - Tumor encasing aorta and/or major branches
subclass of: ImageDefinedRiskFactor
definition: Tumor encasing aorta and/or major branches.

THORAX_LOWER_MEDIASTINUM_INFILTRATING
type: Class
title: Thorax - Lower mediastinal tumor infiltrating costo-vertebral junction
subclass of: ImageDefinedRiskFactor
definition: Lower mediastinal tumor infiltrating the costo-vertebral junction between T9 and T12.

HEIC
type: Class
subclass of: ImageFileFormatEnum
definition: High Efficiency Image Container
extension: .heic, .heif
mime type: image/heic
use: Apple devices

ICO
type: Class
subclass of: ImageFileFormatEnum
definition: Icon file format
extension: .ico
mime type: image/x-icon
use: favicons, app icons

RAW
type: Class
subclass of: ImageFileFormatEnum
definition: Raw image format
extension: .raw, .cr2, .nef, .arw
type: unprocessed sensor data

WEBP
type: Class
subclass of: ImageFileFormatEnum
definition: WebP image format
compression: lossy and lossless
extension: .webp
mime type: image/webp

CODEX
type: Class
subclass of: ImagingAssayEnum
definition: CO-Detection by indEXing imaging

DIFFUSION_MRI
type: Class
subclass of: ImagingAssayEnum
alternative label: DWI
definition: Diffusion-weighted MRI

HIGH_FREQUENCY_ULTRASOUND
type: Class
subclass of: ImagingAssayEnum
definition: High frequency ultrasound imaging

IMMUNOCYTOCHEMISTRY
type: Class
subclass of: ImagingAssayEnum
alternative label: ICC
definition: Immunocytochemistry staining

LASER_SPECKLE_IMAGING
type: Class
subclass of: ImagingAssayEnum
definition: Laser speckle contrast imaging

LIVE_IMAGING
type: Class
subclass of: ImagingAssayEnum
definition: Live cell or tissue imaging

MPRAGE_MRI
type: Class
subclass of: ImagingAssayEnum
alternative label: MPRAGE
definition: Magnetization-Prepared Rapid Gradient Echo MRI

OPTICAL_TOMOGRAPHY
type: Class
subclass of: ImagingAssayEnum
definition: Optical tomography

PHOTOGRAPH
type: Class
subclass of: ImagingAssayEnum
definition: Photographic documentation

SPATIAL_FREQUENCY_DOMAIN_IMAGING
type: Class
subclass of: ImagingAssayEnum
definition: Spatial frequency domain imaging

THREE_D_CONFOCAL_IMAGING
type: Class
subclass of: ImagingAssayEnum
alternative label: 3D confocal imaging
definition: Three-dimensional confocal imaging

THREE_D_ELECTRON_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
alternative label: 3D EM
definition: Three-dimensional electron microscopy

TRACTION_FORCE_MICROSCOPY
type: Class
subclass of: ImagingAssayEnum
definition: Traction force microscopy

TRANSCRANIAL_DOPPLER
type: Class
subclass of: ImagingAssayEnum
definition: Transcranial doppler ultrasonography

BD_FACSSYMPHONY
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: BD FACSymphony
definition: BD FACSymphony flow cytometer
manufacturer: BD Biosciences
type: flow cytometer

BD_FACS_CALIBUR
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: BD FACS Calibur
definition: BD FACS Calibur flow cytometer
manufacturer: BD Biosciences
type: flow cytometer

BIORAD_CHEMIDOC_MP
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: BioRad ChemiDoc MP Imaging System
definition: BioRad ChemiDoc MP Imaging System
manufacturer: BioRad
type: gel/western imager

ENVISION_MULTIPLATE_READER
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: EnVision 2103 Multiplate Reader
definition: PerkinElmer EnVision 2103 Multiplate Reader
manufacturer: PerkinElmer
type: plate reader

IVIS_SPECTRUM
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: IVIS Spectrum In Vivo Imaging System
definition: PerkinElmer IVIS Spectrum In Vivo Imaging System
manufacturer: PerkinElmer
type: in vivo bioluminescence

LICOR_ODYSSEY_CLX
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: LI-COR Odyssey CLx
definition: LI-COR Odyssey CLx Imaging System
manufacturer: LI-COR
type: western blot imager

NANOSTRING_COSMX
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Nanostring CosMx
definition: NanoString CosMx Spatial Molecular Imager
manufacturer: NanoString
type: spatial transcriptomics

NANOSTRING_GEOMX
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Nanostring GeoMx
definition: NanoString GeoMx Digital Spatial Profiler
manufacturer: NanoString
type: spatial profiling

PROMEGA_GLOMAX_DISCOVER
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Promega GloMax Discover
definition: Promega GloMax Discover
manufacturer: Promega
type: plate reader

SPECTRAMAX_M_SERIES
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Spectramax M Series
definition: Molecular Devices SpectraMax M Series
manufacturer: Molecular Devices
type: plate reader

VARIOSKAN_LUX
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Varioskan LUX
definition: Thermo Scientific Varioskan LUX
manufacturer: Thermo Fisher
type: plate reader

VECTRA_H1
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Vectra H1 3D Imaging System
definition: Vectra H1 3D Imaging System (Perkin Elmer)
manufacturer: PerkinElmer
type: multispectral imaging

VENTANA_BENCHMARK_XT
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Ventana Benchmark XT
definition: Ventana Benchmark XT automated staining
manufacturer: Roche
type: automated IHC stainer

VEVO_3100
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: Vevo 3100 Imaging System
definition: Vevo 3100 Imaging System (ultrasound)
manufacturer: FUJIFILM VisualSonics
type: ultrasound

VISIUM_10X
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: 10x Visium Spatial Gene Expression
definition: 10x Genomics Visium Spatial Gene Expression
manufacturer: 10x Genomics
type: spatial transcriptomics

XF24_EXTRACELLULAR_FLUX
type: Class
subclass of: ImagingSystemPlatformEnum
alternative label: XF24 Extracellular Flux Analyzer
definition: Agilent XF24 Extracellular Flux Analyzer
manufacturer: Agilent/Seahorse
type: metabolic analyzer

ACIDIC_CHLORIDE
type: Class
subclass of: InSituChemistryRegime
definition: Hydrochloric acid or chloride-based leaching

ACIDIC_SULFATE
type: Class
subclass of: InSituChemistryRegime
definition: Sulfuric acid-based leaching system

AMMONIA_BASED
type: Class
subclass of: InSituChemistryRegime
definition: Ammonia or ammonium-based leaching system

BIOLEACH_IRON_OXIDIZING
type: Class
subclass of: InSituChemistryRegime
definition: Bioleaching using iron-oxidizing bacteria

BIOLEACH_SULFUR_OXIDIZING
type: Class
subclass of: InSituChemistryRegime
definition: Bioleaching using sulfur-oxidizing bacteria

ORGANIC_ACID
type: Class
subclass of: InSituChemistryRegime
definition: Organic acid leaching (citric, oxalic, etc.)

ACID_ORANGE_7
type: Class
subclass of: IndustrialDyeEnum
definition: Acid Orange 7 (Orange II)
chemical: C16H11N2NaO4S
hex: FF7F00
use: wool, silk dyeing

ANILINE_BLACK
type: Class
subclass of: IndustrialDyeEnum
definition: Aniline black
chemical: polyaniline
hex: 000000
use: cotton dyeing

DISPERSE_BLUE_1
type: Class
subclass of: IndustrialDyeEnum
definition: Disperse Blue 1
hex: 1560BD
use: polyester dyeing

INDIGO
type: Class
subclass of: IndustrialDyeEnum
definition: Indigo dye
hex: 4B0082
source: originally plant-based, now synthetic
use: denim, textiles

METHYLENE_BLUE
type: Class
subclass of: IndustrialDyeEnum
definition: Methylene blue
chemical: C16H18ClN3S
hex: 1E90FF
use: biological stain, medical

REACTIVE_BLACK_5
type: Class
subclass of: IndustrialDyeEnum
definition: Reactive Black 5
hex: 000000
use: cotton reactive dye

SAFRANIN
type: Class
subclass of: IndustrialDyeEnum
definition: Safranin O
chemical: C20H19ClN4
hex: FF0066
use: biological stain

VAT_BLUE_1
type: Class
subclass of: IndustrialDyeEnum
definition: Vat Blue 1 (Indanthrene blue)
hex: 002F5C
use: cotton vat dyeing

DECLINING
type: Class
title: Declining Industry
subclass of: IndustryMaturityEnum
definition: Industry experiencing contraction
characteristics: decreasing demand
competition: intensifying competition for shrinking market
consolidation: significant consolidation
cost focus: focus on cost reduction
exit: companies exiting industry

EMERGING
type: Class
title: Emerging Industry
subclass of: IndustryMaturityEnum
definition: New industry in early development stage
characteristics: high uncertainty, rapid change
competition: few competitors, unclear standards
growth: high growth potential
investment: high investment requirements
technology: new or evolving technology

GROWTH
type: Class
title: Growth Industry
subclass of: IndustryMaturityEnum
definition: Industry experiencing rapid expansion
characteristics: rapid market expansion
competition: increasing competition
investment: significant investment opportunities
profitability: improving profitability
standardization: emerging standards

MATURE
type: Class
title: Mature Industry
subclass of: IndustryMaturityEnum
definition: Established industry with stable growth
characteristics: stable market conditions
competition: established competitive structure
consolidation: potential for consolidation
efficiency: focus on operational efficiency
growth: slower, steady growth

TRANSFORMING
type: Class
title: Transforming Industry
subclass of: IndustryMaturityEnum
definition: Industry undergoing fundamental change
business models: evolving business models
characteristics: disruptive change and innovation
opportunity: opportunities for innovation and disruption
technology: technology-driven transformation
uncertainty: high uncertainty about future structure

DEREGULATED
type: Class
title: Deregulated
subclass of: IndustryRegulationLevelEnum
definition: Industries formerly regulated but now market-based
benefits: increased competition and efficiency
competition: market-based competition
examples: airlines, telecommunications, energy
history: formerly regulated industries
transition: transition from regulation to competition

HIGHLY_REGULATED
type: Class
title: Highly Regulated
subclass of: IndustryRegulationLevelEnum
definition: Industries subject to extensive government oversight
barriers: regulatory barriers to entry
compliance: complex compliance requirements
examples: banking, healthcare, utilities, pharmaceuticals
oversight: extensive government oversight
reason: public safety, market power, or systemic risk

LIGHTLY_REGULATED
type: Class
title: Lightly Regulated
subclass of: IndustryRegulationLevelEnum
definition: Industries with minimal regulatory oversight
approach: market-based approach
compliance: basic compliance requirements
examples: technology, consulting, retail
flexibility: high operational flexibility
oversight: minimal regulatory oversight

MODERATELY_REGULATED
type: Class
title: Moderately Regulated
subclass of: IndustryRegulationLevelEnum
definition: Industries with significant but focused regulation
areas: targeted regulatory areas
balance: balance between oversight and flexibility
compliance: specific compliance requirements
examples: food service, transportation, insurance
oversight: focused regulatory oversight

SELF_REGULATED
type: Class
title: Self-Regulated
subclass of: IndustryRegulationLevelEnum
definition: Industries primarily regulated by industry organizations
compliance: voluntary compliance
effectiveness: varies by industry
examples: professional services, trade associations
oversight: industry self-regulation
standards: industry-developed standards

ASHMORE_AND_CARTIER_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Ashmore and Cartier Islands
note: Australian external territory

BASSAS_DA_INDIA
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Bassas da India
note: French Southern and Antarctic Lands territory

CLIPPERTON_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Clipperton Island
note: French overseas territory

CORAL_SEA_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Coral Sea Islands
note: Australian external territory

EUROPA_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Europa Island
note: French Southern and Antarctic Lands territory

GAZA_STRIP
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Gaza Strip
note: Palestinian territory

GLORIOSO_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Glorioso Islands
note: French Southern and Antarctic Lands territory

JAN_MAYEN
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Jan Mayen
note: Norwegian territory

JUAN_DE_NOVA_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Juan de Nova Island
note: French Southern and Antarctic Lands territory

KERGUELEN_ARCHIPELAGO
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Kerguelen Archipelago
note: French Southern and Antarctic Lands territory

LINE_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Line Islands
note: Island group in Pacific Ocean (part of Kiribati)

PARACEL_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Paracel Islands
note: Disputed territory in South China Sea

SPRATLY_ISLANDS
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Spratly Islands
note: Disputed territory in South China Sea

SVALBARD
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Svalbard
note: Norwegian territory (part of Svalbard and Jan Mayen - SJ)

TROMELIN_ISLAND
type: Class
subclass of: InsdcGeographicLocationEnum
definition: Tromelin Island
note: French Southern and Antarctic Lands territory

WEST_BANK
type: Class
subclass of: InsdcGeographicLocationEnum
definition: West Bank
note: Palestinian territory

MISSING_CONTROL_SAMPLE
type: Class
subclass of: InsdcMissingValueEnum
definition: Information is not applicable to control samples, negative control samples (e.g. blank sample or clear sample)
note: No specific ontology term found for missing control sample data

MISSING_DATA_AGREEMENT_ESTABLISHED_PRE_2023
type: Class
subclass of: InsdcMissingValueEnum
definition: Information can not be reported due to a data agreement established before metadata standards were introduced in 2023
note: No specific ontology term for data missing due to pre-2023 agreements

MISSING_ENDANGERED_SPECIES
type: Class
subclass of: InsdcMissingValueEnum
definition: Information can not be reported due to endangered species concerns
note: No specific ontology term for data withheld due to endangered species

MISSING_HUMAN_IDENTIFIABLE
type: Class
subclass of: InsdcMissingValueEnum
definition: Information can not be reported due to identifiable human data concerns
note: No specific ontology term for data withheld due to human identifiability

MISSING_LAB_STOCK
type: Class
subclass of: InsdcMissingValueEnum
definition: Information is not collected for a lab stock and its cultivation, e.g. stock centers, culture collections, seed banks
note: No specific ontology term found for missing lab stock data

MISSING_SAMPLE_GROUP
type: Class
subclass of: InsdcMissingValueEnum
definition: Information can not be provided for a sample group where a selection of samples is used to represent a species, location or some other attribute/metric
note: No specific ontology term found for missing sample group data

MISSING_SYNTHETIC_CONSTRUCT
type: Class
subclass of: InsdcMissingValueEnum
definition: Information does not exist for a synthetic construct
note: No specific ontology term found for missing synthetic construct data

CONSTRUCTION_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Construction phase inspections

CYBER_SECURITY
type: Class
subclass of: InspectionTypeEnum
definition: Cybersecurity program inspections

DECOMMISSIONING_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Decommissioning activities inspections

EMERGENCY_PREPAREDNESS
type: Class
subclass of: InspectionTypeEnum
definition: Emergency preparedness and response inspections

FORCE_ON_FORCE
type: Class
subclass of: InspectionTypeEnum
definition: Security force-on-force exercises

INTEGRATED_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Integrated inspection program

PERIODIC_SAFETY_REVIEW
type: Class
subclass of: InspectionTypeEnum
definition: Comprehensive periodic safety reviews

PRE_OPERATIONAL_TESTING
type: Class
subclass of: InspectionTypeEnum
definition: Pre-operational testing and commissioning inspections

REACTIVE_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Event-driven or follow-up inspections

ROUTINE_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Regularly scheduled inspection activities

SPECIAL_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Special inspections for significant events

STARTUP_TESTING
type: Class
subclass of: InspectionTypeEnum
definition: Initial startup and power ascension inspections

TEAM_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Multi-disciplinary team inspections

TRIENNIAL_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Three-year cycle comprehensive inspections

VENDOR_INSPECTION
type: Class
subclass of: InspectionTypeEnum
definition: Nuclear vendor and supplier inspections

AUDIT_TRAIL
type: Class
title: audit trail
subclass of: IntegrationFeatureEnum
definition: Complete logging of all operations for compliance

AUTOMATED_DATA_TRANSFER
type: Class
title: automated data transfer
subclass of: IntegrationFeatureEnum
definition: Automatic transfer of data between systems

BARCODE_TRACKING
type: Class
title: barcode tracking
subclass of: IntegrationFeatureEnum
definition: Integration feature for tracking samples via barcodes

CLOUD_STORAGE_INTEGRATION
type: Class
title: cloud storage integration
subclass of: IntegrationFeatureEnum
definition: Integration with cloud-based storage systems

ELECTRONIC_SIGNATURES
type: Class
title: electronic signatures
subclass of: IntegrationFeatureEnum
definition: Support for electronic signatures for regulatory compliance

ERROR_RECOVERY
type: Class
title: error recovery
subclass of: IntegrationFeatureEnum
definition: Automated error detection and recovery mechanisms

SAMPLE_TRACKING
type: Class
title: sample tracking
subclass of: IntegrationFeatureEnum
definition: Real-time tracking of sample location and status

WORKFLOW_VALIDATION
type: Class
title: workflow validation
subclass of: IntegrationFeatureEnum
definition: Automated validation of workflow definitions

CLOUD_STORAGE
type: Class
title: cloud storage
subclass of: IntegrationSystemEnum
definition: Cloud-based data storage systems

DATABASE
type: Class
title: database
subclass of: IntegrationSystemEnum
definition: Laboratory database systems

ELN
type: Class
subclass of: IntegrationSystemEnum
definition: Electronic Laboratory Notebook
full name: Electronic Laboratory Notebook

LIMS
type: Class
subclass of: IntegrationSystemEnum
definition: Laboratory Information Management System
full name: Laboratory Information Management System

MES
type: Class
subclass of: IntegrationSystemEnum
definition: Manufacturing Execution System
full name: Manufacturing Execution System

SCADA
type: Class
subclass of: IntegrationSystemEnum
definition: Supervisory Control and Data Acquisition
full name: Supervisory Control and Data Acquisition

CANCEL
type: Class
title: Cancel
subclass of: IntentClassificationEnum
definition: User intent to cancel

COMPLAINT
type: Class
title: Complaint
subclass of: IntentClassificationEnum
definition: User expressing dissatisfaction

FEEDBACK
type: Class
title: Feedback
subclass of: IntentClassificationEnum
definition: User providing feedback

GOODBYE
type: Class
title: Goodbye
subclass of: IntentClassificationEnum
definition: User saying goodbye

GREETING
type: Class
title: Greeting
subclass of: IntentClassificationEnum
definition: User greeting or hello

HELP
type: Class
title: Help
subclass of: IntentClassificationEnum
definition: User requesting help or assistance

INFORMATION
type: Class
title: Information
subclass of: IntentClassificationEnum
definition: User requesting information

PURCHASE
type: Class
title: Purchase
subclass of: IntentClassificationEnum
definition: User intent to buy or purchase

REFUND
type: Class
title: Refund
subclass of: IntentClassificationEnum
definition: User requesting refund

THANKS
type: Class
title: Thanks
subclass of: IntentClassificationEnum
definition: User expressing gratitude

LIPID
type: Class
subclass of: InteractorType
definition: Lipid molecule

METAL_ION
type: Class
subclass of: InteractorType
definition: Metal ion cofactor

SYNTHETIC_POLYMER
type: Class
subclass of: InteractorType
definition: Artificial polymer

ABC_ANALYSIS
type: Class
title: ABC Analysis
subclass of: InventoryManagementApproachEnum
definition: Inventory classification by value importance
classification: value-based classification
efficiency: resource allocation efficiency
focus: priority focus on high-value items
management: differentiated management
pareto: Pareto principle application

CONSIGNMENT_INVENTORY
type: Class
title: Consignment Inventory
subclass of: InventoryManagementApproachEnum
definition: Supplier-owned inventory at customer location
availability: immediate availability
cash flow: improved cash flow
location: customer location
ownership: supplier ownership
risk: supplier risk

CONTINUOUS_REVIEW
type: Class
title: Continuous Review System
subclass of: InventoryManagementApproachEnum
definition: Continuous monitoring with fixed reorder point
cost: higher monitoring cost
monitoring: continuous inventory monitoring
quantity: fixed order quantity
reorder point: fixed reorder point
responsiveness: responsive to demand

ECONOMIC_ORDER_QUANTITY
type: Class
title: Economic Order Quantity (EOQ)
subclass of: InventoryManagementApproachEnum
definition: Optimal order quantity calculation
calculation: mathematical calculation
classical: classical inventory model
optimization: cost optimization
static: static demand assumption
trade off: ordering vs holding cost trade-off

JUST_IN_TIME
type: Class
title: Just-in-Time (JIT)
subclass of: InventoryManagementApproachEnum
definition: Minimal inventory with precise timing
flow: continuous flow
quality: zero defect requirement
supplier: supplier integration
timing: precise delivery timing
waste: inventory waste elimination

KANBAN
type: Class
title: Kanban System
subclass of: InventoryManagementApproachEnum
definition: Visual pull-based inventory system
flow: smooth material flow
lean: lean methodology
pull: pull-based replenishment
signals: kanban signals
visual: visual control system

PERIODIC_REVIEW
type: Class
title: Periodic Review System
subclass of: InventoryManagementApproachEnum
definition: Periodic inventory review with variable order quantity
aggregation: order aggregation
efficiency: administrative efficiency
periodic: periodic review intervals
target: target inventory level
variable: variable order quantity

SAFETY_STOCK
type: Class
title: Safety Stock Management
subclass of: InventoryManagementApproachEnum
definition: Buffer inventory for demand/supply uncertainty
buffer: inventory buffer
cost: additional holding cost
risk: stockout risk mitigation
service level: service level protection
uncertainty: demand and supply uncertainty

TWO_BIN_SYSTEM
type: Class
title: Two-Bin System
subclass of: InventoryManagementApproachEnum
definition: Simple reorder point system using two bins
automatic: automatic reordering
bins: two-bin methodology
low cost: low-cost implementation
simplicity: simple reorder system
visual: visual reorder point

VENDOR_MANAGED_INVENTORY
type: Class
title: Vendor Managed Inventory (VMI)
subclass of: InventoryManagementApproachEnum
definition: Supplier-controlled inventory management
automation: automated replenishment
control: supplier inventory control
efficiency: inventory efficiency
partnership: supplier partnership
visibility: demand visibility

C_LEVEL
type: Class
title: C-Level Executive
subclass of: JobLevelEnum
definition: Chief executive level
fiduciary: fiduciary responsibility
governance: corporate governance
scope: enterprise-wide responsibility
stakeholders: external stakeholder management
vision: organizational vision

DIRECTOR
type: Class
title: Director
subclass of: JobLevelEnum
definition: Director level executive
leadership: organizational leadership
results: business results accountability
scope: multi-departmental oversight
stakeholders: senior stakeholder management
strategy: strategic planning

ENTRY_LEVEL
type: Class
title: Entry Level
subclass of: JobLevelEnum
definition: Beginning career level positions
career stage: career beginning
development: learning and development focus
experience: 0-2 years experience
responsibilities: basic operational tasks
supervision: high supervision required

JUNIOR
type: Class
title: Junior Level
subclass of: JobLevelEnum
definition: Junior professional level
experience: 2-4 years experience
independence: some independence
mentorship: receiving mentorship
responsibilities: routine professional tasks
skill building: skill development phase

LEAD
type: Class
title: Team Lead
subclass of: JobLevelEnum
definition: Team leadership role
accountability: team results
coordination: team coordination
development: team development
people management: direct reports
responsibility: team leadership

MANAGER
type: Class
title: Manager
subclass of: JobLevelEnum
definition: Management level position
budget: budget responsibility
operations: operational management
people management: multiple direct reports
scope: departmental management
strategy: tactical strategy

MID_LEVEL
type: Class
title: Mid-Level
subclass of: JobLevelEnum
definition: Experienced professional level
experience: 4-8 years experience
expertise: developing expertise
independence: high independence
mentorship: providing and receiving mentorship
responsibilities: complex project work

SENIOR
type: Class
title: Senior Level
subclass of: JobLevelEnum
definition: Senior professional level
experience: 8+ years experience
expertise: subject matter expertise
influence: organizational influence
mentorship: mentoring others
responsibilities: strategic project leadership

VP
type: Class
title: Vice President
subclass of: JobLevelEnum
definition: Vice President executive level
board: board interaction
organization: organizational impact
scope: business unit or functional area
strategy: strategic leadership
succession: succession planning

OTHER_KARYOTYPE
type: Class
subclass of: KaryotypicSexEnum
definition: Other karyotypic sex not listed
note: May include complex chromosomal arrangements

AUTOMATED_SYNTHESIS
type: Class
subclass of: LabAutomationWorkflowType
definition: Workflow for automated execution of chemical or biological synthesis procedures
characteristic: automated reaction execution

AUTONOMOUS_CHARACTERIZATION
type: Class
subclass of: LabAutomationWorkflowType
definition: Workflow for automated sample characterization using multiple analytical techniques
characteristic: multi-modal automated measurement

CLOSED_LOOP_OPTIMIZATION
type: Class
subclass of: LabAutomationWorkflowType
definition: Workflow where experimental results are automatically fed back to guide subsequent experiments
characteristic: feedback-driven iterative optimization

ROBOTIC_SAMPLE_PREPARATION
type: Class
subclass of: LabAutomationWorkflowType
broad match: OBI_0000073
definition: Workflow for automated preparation of samples for analysis or further processing
characteristic: automated sample handling and preparation

SELF_DRIVING_EXPERIMENTATION
type: Class
subclass of: LabAutomationWorkflowType
definition: Fully autonomous workflow combining AI-driven planning, execution, and analysis without human intervention
characteristic: end-to-end autonomous operation

BARCODE_READER
type: Class
title: barcode reader
subclass of: LaboratoryDeviceTypeEnum
definition: A device that reads barcode labels on laboratory samples and containers

COLONY_PICKER
type: Class
title: colony picker
subclass of: LaboratoryDeviceTypeEnum
definition: An automated device for selecting and transferring individual bacterial or yeast colonies

DISPENSER
type: Class
title: dispenser
subclass of: LaboratoryDeviceTypeEnum
definition: A device for automated dispensing of reagents or samples

PLATE_HANDLER
type: Class
title: plate handler
subclass of: LaboratoryDeviceTypeEnum
definition: An automated device designed to transfer microplates between workstations and lab instruments

THERMAL_CYCLER
type: Class
title: thermal cycler
subclass of: LaboratoryDeviceTypeEnum
definition: A laboratory apparatus used to amplify DNA segments via the polymerase chain reaction

ANSI_SLAS_1_2004
type: Class
title: ANSI/SLAS 1-2004
subclass of: LabwareStandardEnum
definition: Microplates - Footprint Dimensions
reaffirmed: 2012
specification: Footprint Dimensions

ANSI_SLAS_2_2004
type: Class
title: ANSI/SLAS 2-2004
subclass of: LabwareStandardEnum
definition: Microplates - Height Dimensions
reaffirmed: 2012
specification: Height Dimensions

ANSI_SLAS_3_2004
type: Class
title: ANSI/SLAS 3-2004
subclass of: LabwareStandardEnum
definition: Microplates - Bottom Outside Flange Dimensions
reaffirmed: 2012
specification: Bottom Outside Flange Dimensions

ANSI_SLAS_4_2004
type: Class
title: ANSI/SLAS 4-2004
subclass of: LabwareStandardEnum
definition: Microplates - Well Positions
reaffirmed: 2012
specification: Well Positions

ANSI_SLAS_6_2012
type: Class
title: ANSI/SLAS 6-2012
subclass of: LabwareStandardEnum
definition: Microplates - Well Bottom Elevation
specification: Well Bottom Elevation

SBS_FOOTPRINT
type: Class
title: SBS footprint
subclass of: LabwareStandardEnum
definition: Society for Biomolecular Screening standard footprint (127.76mm x 85.5mm)
dimensions: 127.76mm x 85.5mm

AR
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Arabic

BN
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Bengali

CS
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Czech

DA
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Danish

DE
type: Class
subclass of: LanguageCodeISO6391Enum
definition: German

EL
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Greek

EN
type: Class
subclass of: LanguageCodeISO6391Enum
definition: English

ES
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Spanish

FI
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Finnish

FR
type: Class
subclass of: LanguageCodeISO6391Enum
definition: French

False
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Norwegian

HE
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Hebrew

HI
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Hindi

HU
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Hungarian

IT
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Italian

JA
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Japanese

KO
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Korean

NL
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Dutch

PA
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Punjabi

PL
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Polish

PT
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Portuguese

RO
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Romanian

RU
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Russian

SV
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Swedish

TH
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Thai

TR
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Turkish

UK
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Ukrainian

UR
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Urdu

VI
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Vietnamese

ZH
type: Class
subclass of: LanguageCodeISO6391Enum
definition: Chinese

MIDLINE
type: Class
subclass of: LateralityEnum
definition: In the midline/center
note: Along the body's central axis

AUTHENTIC
type: Class
title: Authentic Leadership
subclass of: LeadershipStyleEnum
definition: Genuine and self-aware leadership approach
authenticity: genuine and authentic
integrity: personal integrity
self awareness: high self-awareness
values: values-based leadership

AUTOCRATIC
type: Class
title: Autocratic Leadership
subclass of: LeadershipStyleEnum
definition: Directive leadership with centralized control
authority: strong authority
control: centralized control
directive: directive approach
efficiency: decision efficiency

CHARISMATIC
type: Class
title: Charismatic Leadership
subclass of: LeadershipStyleEnum
definition: Inspiring leadership through personal charisma
charisma: personal charisma
emotion: emotional appeal
following: devoted following
inspiration: inspirational influence

COACHING
type: Class
title: Coaching Leadership
subclass of: LeadershipStyleEnum
definition: Development-focused leadership approach
development: skill and capability development
growth: personal and professional growth
guidance: mentoring and guidance
support: supportive leadership

DEMOCRATIC
type: Class
title: Democratic Leadership
subclass of: LeadershipStyleEnum
definition: Participative leadership with shared decision-making
collaboration: collaborative approach
empowerment: team empowerment
participation: follower participation
shared: shared decision making

LAISSEZ_FAIRE
type: Class
title: Laissez-Faire Leadership
subclass of: LeadershipStyleEnum
definition: Hands-off leadership with minimal interference
autonomy: high follower autonomy
freedom: freedom to operate
minimal: minimal leadership intervention
self direction: self-directed teams

SERVANT
type: Class
title: Servant Leadership
subclass of: LeadershipStyleEnum
definition: Leader serves followers and facilitates their growth
development: personal development focus
empowerment: follower empowerment
humility: humble leadership approach
service: service to followers

SITUATIONAL
type: Class
title: Situational Leadership
subclass of: LeadershipStyleEnum
definition: Adaptive leadership based on situation requirements
adaptation: situational adaptation
assessment: situation assessment
flexibility: flexible approach
style variation: varying leadership styles

TRANSACTIONAL
type: Class
title: Transactional Leadership
subclass of: LeadershipStyleEnum
definition: Exchange-based leadership with rewards and consequences
exchange: reward and consequence based
management: management by exception
performance: performance-based
structure: structured approach

TRANSFORMATIONAL
type: Class
title: Transformational Leadership
subclass of: LeadershipStyleEnum
definition: Inspirational leadership that motivates change
change: change-oriented
development: follower development
inspiration: inspirational motivation
vision: visionary leadership

B_CORPORATION
type: Class
title: Benefit Corporation (B-Corp)
subclass of: LegalEntityTypeEnum
definition: Corporation with social and environmental mission
accountability: stakeholder governance requirements
certification: optional third-party certification
purpose: profit and public benefit
transparency: annual benefit reporting

COOPERATIVE
type: Class
title: Cooperative
subclass of: LegalEntityTypeEnum
definition: Member-owned and democratically controlled organization
benefits: benefits proportional to participation
control: democratic member control
ownership: member ownership
purpose: mutual benefit of members

C_CORPORATION
type: Class
title: C Corporation
subclass of: LegalEntityTypeEnum
definition: Traditional corporation with double taxation
governance: formal board and officer structure
legal status: separate legal entity
liability: limited liability for shareholders
stock: can issue multiple classes of stock
taxation: double taxation (corporate and dividend)

FRANCHISE
type: Class
title: Franchise
subclass of: LegalEntityTypeEnum
definition: Business operating under franchisor's brand and system
brand: operates under established brand
fees: pays franchise fees and royalties
relationship: franchisor-franchisee relationship
system: follows franchisor's business system

GENERAL_PARTNERSHIP
type: Class
title: General Partnership
subclass of: LegalEntityTypeEnum
definition: Business owned by two or more partners sharing responsibilities
liability: unlimited personal liability for all partners
management: shared management responsibilities
ownership: shared among general partners
taxation: pass-through to partners

GOVERNMENT_ENTITY
type: Class
title: Government Entity
subclass of: LegalEntityTypeEnum
definition: Entity owned and operated by government
funding: government funding sources
ownership: government ownership
purpose: public service or policy implementation
regulation: government regulations and oversight

HOLDING_COMPANY
type: Class
title: Holding Company
subclass of: LegalEntityTypeEnum
definition: Company that owns controlling interests in other companies
control: controls subsidiaries through ownership
operations: minimal direct operations
purpose: own and control subsidiary companies
structure: parent-subsidiary relationships

JOINT_VENTURE
type: Class
title: Joint Venture
subclass of: LegalEntityTypeEnum
definition: Temporary partnership for specific project or purpose
duration: temporary or project-specific
liability: depends on structure chosen
ownership: shared ownership of venture
purpose: specific business objective

LIMITED_LIABILITY_COMPANY
type: Class
title: Limited Liability Company (LLC)
subclass of: LegalEntityTypeEnum
definition: Hybrid entity combining corporation and partnership features
formality: fewer formal requirements than corporations
liability: limited liability protection
management: flexible management structure
taxation: flexible tax election options

LIMITED_LIABILITY_PARTNERSHIP
type: Class
title: Limited Liability Partnership (LLP)
subclass of: LegalEntityTypeEnum
definition: Partnership providing liability protection to all partners
liability: limited liability for all partners
management: flexible management structure
professional use: often used by professional services
taxation: pass-through taxation

LIMITED_PARTNERSHIP
type: Class
title: Limited Partnership (LP)
subclass of: LegalEntityTypeEnum
definition: Partnership with general and limited partners
liability: general partners have unlimited liability
limited liability: limited partners have liability protection
management: general partners manage operations
partner types: general partners and limited partners

MULTI_MEMBER_LLC
type: Class
title: Multi-Member LLC
subclass of: LegalEntityTypeEnum
definition: LLC with multiple owners/members
liability: limited liability protection
operating agreement: recommended operating agreement
ownership: multiple members
taxation: partnership taxation by default

NONPROFIT_CORPORATION
type: Class
title: Nonprofit Corporation
subclass of: LegalEntityTypeEnum
definition: Corporation organized for charitable or public purposes
governance: board of directors governance
profit distribution: no profit distribution to members
purpose: charitable, educational, or public benefit
taxation: tax-exempt status possible

PRIVATE_CORPORATION
type: Class
title: Private Corporation
subclass of: LegalEntityTypeEnum
definition: Corporation with privately held shares
liquidity: limited share liquidity
regulation: fewer regulatory requirements
shareholders: limited number of shareholders
shares: privately held shares

PUBLIC_CORPORATION
type: Class
title: Public Corporation
subclass of: LegalEntityTypeEnum
definition: Corporation with publicly traded shares
governance: extensive governance requirements
liquidity: high share liquidity
regulation: SEC reporting requirements
shares: publicly traded on stock exchanges

SINGLE_MEMBER_LLC
type: Class
title: Single Member LLC
subclass of: LegalEntityTypeEnum
definition: LLC with only one owner/member
liability: limited liability protection
ownership: single member
simplicity: simpler than multi-member LLC
taxation: disregarded entity for tax purposes

SOLE_PROPRIETORSHIP
type: Class
title: Sole Proprietorship
subclass of: LegalEntityTypeEnum
definition: Business owned and operated by single individual
complexity: simplest structure
legal separation: no separation from owner
liability: unlimited personal liability
registration: minimal requirements
taxation: pass-through to personal returns

SUBSIDIARY
type: Class
title: Subsidiary
subclass of: LegalEntityTypeEnum
definition: Company controlled by another company (parent)
control: controlled by parent company
liability: separate legal entity
operations: may operate independently
ownership: majority owned by parent

S_CORPORATION
type: Class
title: S Corporation
subclass of: LegalEntityTypeEnum
definition: Corporation electing pass-through taxation
eligibility: restrictions on shareholder types
shareholders: limited to 100 shareholders
stock types: single class of stock only
taxation: pass-through to shareholders

LewisAcidBaseRoleEnum
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Lewis Acid Base Role
status: DRAFT
subclass of: ChemicalEntitiesSchemaEnum
union of: LEWIS_ACID
union of: LEWIS_BASE
definition: Lewis acid-base roles
in scheme: merged
permissible values: LEWIS_ACID
permissible values: LEWIS_BASE
source domain: chemistry
source schema: chemical_entities

LEWIS_ACID
type: Class
subclass of: LewisAcidBaseRoleEnum
definition: Electron pair acceptor
definition: species that accepts electron pair
examples: BF3, AlCl3, H+

LEWIS_BASE
type: Class
subclass of: LewisAcidBaseRoleEnum
definition: Electron pair donor
definition: species that donates electron pair
examples: NH3, OH-, H2O

AMPLICON_SEQUENCING
type: Class
subclass of: LibraryPreparation
definition: 16S/ITS amplicon sequencing

ATAC_SEQ
type: Class
subclass of: LibraryPreparation
definition: ATAC-seq (chromatin accessibility)

BISULFITE_SEQ
type: Class
subclass of: LibraryPreparation
definition: Bisulfite sequencing (methylation)

CAPTURE_SEQUENCING
type: Class
subclass of: LibraryPreparation
definition: Target capture/enrichment sequencing

CDNA_SEQUENCING
type: Class
subclass of: LibraryPreparation
definition: cDNA sequencing

CHIP_SEQ
type: Class
subclass of: LibraryPreparation
definition: ChIP-seq (chromatin immunoprecipitation)

CUT_AND_RUN
type: Class
subclass of: LibraryPreparation
definition: CUT&RUN (chromatin profiling)

CUT_AND_TAG
type: Class
subclass of: LibraryPreparation
definition: CUT&Tag (chromatin profiling)

DIRECT_RNA
type: Class
subclass of: LibraryPreparation
definition: Direct RNA sequencing (nanopore)

EXOME_SEQUENCING
type: Class
subclass of: LibraryPreparation
definition: Whole exome sequencing

GENOMIC_DNA
type: Class
subclass of: LibraryPreparation
definition: Genomic DNA library preparation

HI_C
type: Class
subclass of: LibraryPreparation
definition: Hi-C (chromosome conformation capture)

METAGENOMICS
type: Class
subclass of: LibraryPreparation
definition: Metagenomic sequencing

PCR_AMPLICON
type: Class
subclass of: LibraryPreparation
definition: PCR amplicon sequencing

RIBOSOME_PROFILING
type: Class
subclass of: LibraryPreparation
definition: Ribosome profiling (Ribo-seq)

RNA_SEQ
type: Class
subclass of: LibraryPreparation
definition: RNA sequencing library prep

SINGLE_CELL_RNA_SEQ
type: Class
subclass of: LibraryPreparation
definition: Single-cell RNA sequencing

SMALL_RNA_SEQ
type: Class
subclass of: LibraryPreparation
definition: Small RNA sequencing

WHOLE_GENOME_AMPLIFICATION
type: Class
subclass of: LibraryPreparation
definition: Whole genome amplification (WGA)

CUSTOM
type: Class
subclass of: LicenseType
definition: Custom license terms

PROPRIETARY
type: Class
subclass of: LicenseType
definition: Proprietary/All rights reserved

COMBINED_LICENSE
type: Class
subclass of: LicensingStageEnum
definition: Combined construction and operating license

CONSTRUCTION_PERMIT
type: Class
subclass of: LicensingStageEnum
definition: Construction permit application and review

DECOMMISSIONING_PLAN
type: Class
subclass of: LicensingStageEnum
definition: Decommissioning plan approval

DESIGN_CERTIFICATION
type: Class
subclass of: LicensingStageEnum
definition: Standard design certification

EARLY_SITE_PERMIT
type: Class
subclass of: LicensingStageEnum
definition: Early site permit for future construction

LICENSE_RENEWAL
type: Class
subclass of: LicensingStageEnum
definition: License renewal application and review

LICENSE_TERMINATION
type: Class
subclass of: LicensingStageEnum
definition: License termination and site release

OPERATING_LICENSE
type: Class
subclass of: LicensingStageEnum
definition: Operating license application and review

POWER_UPRATE
type: Class
subclass of: LicensingStageEnum
definition: Power uprate license amendment

PRE_APPLICATION
type: Class
subclass of: LicensingStageEnum
definition: Pre-application consultation and preparation

ACOUSTIC_TRANSFER
type: Class
title: acoustic transfer
subclass of: LiquidHandlingOperationEnum
definition: Acoustic liquid handling that uses acoustics to fly individual droplets from a source container to a destination

ALIQUOTING
type: Class
title: aliquoting
subclass of: LiquidHandlingOperationEnum
definition: Operation to distribute a sample into multiple equal portions

ASPIRATE
type: Class
title: aspirate
subclass of: LiquidHandlingOperationEnum
definition: Operation to draw liquid into pipette tips

DISPENSE
type: Class
title: dispense
subclass of: LiquidHandlingOperationEnum
definition: Operation to dispense liquid from pipette tips

DROP_TIPS
type: Class
title: drop tips
subclass of: LiquidHandlingOperationEnum
definition: Operation to drop or discard pipette tips

MIXING
type: Class
title: mixing
subclass of: LiquidHandlingOperationEnum
definition: Operation to mix liquids by repeated aspiration and dispensing

PICK_UP_TIPS
type: Class
title: pick up tips
subclass of: LiquidHandlingOperationEnum
definition: Operation to pick up pipette tips from a tip rack

PLATE_STAMPING
type: Class
title: plate stamping
subclass of: LiquidHandlingOperationEnum
definition: Operation to transfer samples from one plate to another in the same well pattern

RETURN_TIPS
type: Class
title: return tips
subclass of: LiquidHandlingOperationEnum
definition: Operation to return pipette tips to a tip rack

SERIAL_DILUTION
type: Class
title: serial dilution
subclass of: LiquidHandlingOperationEnum
definition: Operation to create a series of dilutions of a substance in solution

TRANSFER
type: Class
title: transfer
subclass of: LiquidHandlingOperationEnum
definition: Combined operation to aspirate from source and dispense to destination

CROSS_DOCKING
type: Class
title: Cross-Docking Operations
subclass of: LogisticsOperationEnum
definition: Direct transfer without storage
consolidation: shipment consolidation
efficiency: operational efficiency
minimal storage: minimal inventory storage
speed: fast throughput
transfer: direct transfer

DISTRIBUTION
type: Class
title: Distribution Management
subclass of: LogisticsOperationEnum
definition: Product distribution and delivery operations
coverage: market coverage
delivery: customer delivery
distribution: product distribution
network: distribution network
service: delivery service

FOURTH_PARTY_LOGISTICS
type: Class
title: Fourth-Party Logistics (4PL)
subclass of: LogisticsOperationEnum
definition: Supply chain integration and management services
coordination: multi-provider coordination
integration: supply chain integration
management: end-to-end management
strategy: strategic logistics
technology: technology integration

FREIGHT_FORWARDING
type: Class
title: Freight Forwarding
subclass of: LogisticsOperationEnum
definition: International shipping and customs management
compliance: regulatory compliance
coordination: multi-modal coordination
customs: customs clearance
documentation: shipping documentation
international: international shipping

INBOUND_LOGISTICS
type: Class
title: Inbound Logistics
subclass of: LogisticsOperationEnum
definition: Management of incoming materials and supplies
direction: inbound to organization
materials: raw materials and supplies
quality: incoming quality control
receiving: receiving operations
suppliers: supplier coordination

OUTBOUND_LOGISTICS
type: Class
title: Outbound Logistics
subclass of: LogisticsOperationEnum
definition: Management of finished goods distribution
customers: customer delivery
direction: outbound from organization
distribution: distribution management
products: finished goods
service: customer service

REVERSE_LOGISTICS
type: Class
title: Reverse Logistics
subclass of: LogisticsOperationEnum
definition: Management of product returns and recycling
direction: reverse flow
recovery: value recovery
recycling: recycling and disposal
returns: product returns
sustainability: environmental responsibility

THIRD_PARTY_LOGISTICS
type: Class
title: Third-Party Logistics (3PL)
subclass of: LogisticsOperationEnum
definition: Outsourced logistics services
cost: cost optimization
expertise: logistics expertise
outsourcing: logistics outsourcing
service provider: third-party provider
specialization: logistics specialization

TRANSPORTATION
type: Class
title: Transportation Management
subclass of: LogisticsOperationEnum
definition: Movement of goods between locations
cost: transportation cost
modes: transportation modes
movement: goods movement
routing: route optimization
scheduling: delivery scheduling

WAREHOUSING
type: Class
title: Warehousing Operations
subclass of: LogisticsOperationEnum
definition: Storage and inventory management operations
automation: warehouse automation
distribution: distribution center
handling: material handling
inventory: inventory management
storage: product storage

FEATURE
type: Class
subclass of: MLFieldRole
definition: Input features used for model prediction
also known as: input, predictor, independent variable

IDENTIFIER
type: Class
subclass of: MLFieldRole
definition: Unique identifiers for records or entities
also known as: ID, key, primary key

LABEL
type: Class
subclass of: MLFieldRole
definition: Target labels or outputs for supervised learning
also known as: target, output, dependent variable, ground truth

METADATA
type: Class
subclass of: MLFieldRole
definition: Descriptive information about the dataset or records
also known as: descriptive field, provenance

AUDIO_FLAC
type: Class
subclass of: MLMediaType
definition: FLAC lossless audio format
mime type: audio/flac
modality: audio

AUDIO_MP3
type: Class
subclass of: MLMediaType
definition: MP3 audio format
mime type: audio/mpeg
modality: audio

AUDIO_WAV
type: Class
subclass of: MLMediaType
definition: Waveform Audio File Format
mime type: audio/wav
modality: audio

IMAGE_GIF
type: Class
subclass of: MLMediaType
definition: GIF image format
mime type: image/gif
modality: image

IMAGE_TIFF
type: Class
subclass of: MLMediaType
definition: TIFF image format
mime type: image/tiff
modality: image

TEXT_HTML
type: Class
subclass of: MLMediaType
definition: HTML format
mime type: text/html
modality: text

TEXT_PLAIN
type: Class
subclass of: MLMediaType
definition: Plain text format
mime type: text/plain
modality: text

VIDEO_WEBM
type: Class
subclass of: MLMediaType
definition: WebM video format
mime type: video/webm
modality: video

AUDIO
type: Class
subclass of: MLModalityType
definition: Audio/sound data
examples: speech, music, sound effects

GRAPH
type: Class
subclass of: MLModalityType
definition: Graph-structured data with nodes and edges
examples: social networks, knowledge graphs, molecular structures

MULTIMODAL
type: Class
subclass of: MLModalityType
definition: Data combining multiple modalities
examples: image-text pairs, audio-visual data

TABULAR
type: Class
subclass of: MLModalityType
definition: Structured tabular data
examples: spreadsheets, databases, CSV files

TEXT
type: Class
subclass of: MLModalityType
definition: Textual data (natural language, code, etc.)
examples: documents, sentences, tokens

TIME_SERIES
type: Class
subclass of: MLModalityType
definition: Sequential temporal data
examples: sensor readings, stock prices, logs

VIDEO
type: Class
subclass of: MLModalityType
definition: Video data (sequences of images with optional audio)
examples: movies, recordings, animations

BRUKER_BIOSPEC_7T
type: Class
subclass of: MRIPlatformEnum
alternative label: 7T Bruker Biospec
definition: Bruker Biospec 7T research MRI scanner
field strength: 7T
manufacturer: Bruker
type: research

GE_DISCOVERY_MR750_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Discovery MR750 3T
definition: GE Discovery MR750 3T MRI scanner
field strength: 3T
manufacturer: GE Healthcare

GE_OPTIMA_MR450W_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Optima MR450W 1.5T
definition: GE Optima MR450W 1.5T MRI scanner
field strength: 1.5T
manufacturer: GE Healthcare

GE_SIGNA_EXCITE_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Signa Excite 1.5T
definition: GE Signa Excite 1.5T MRI scanner
field strength: 1.5T
manufacturer: GE Healthcare

GE_SIGNA_GENESIS_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Signa Genesis 1.5T
definition: GE Signa Genesis 1.5T MRI scanner
field strength: 1.5T
manufacturer: GE Healthcare

GE_SIGNA_HDXT_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Signa HDxt 1.5T
definition: GE Signa HDxt 1.5T MRI scanner
field strength: 1.5T
manufacturer: GE Healthcare

GE_SIGNA_HDXT_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Signa HDxt 3T
definition: GE Signa HDxt 3T MRI scanner
field strength: 3T
manufacturer: GE Healthcare

GE_SIGNA_PREMIER_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: GE Signa Premier 3T
definition: GE Signa Premier 3T MRI scanner
field strength: 3T
manufacturer: GE Healthcare

HITACHI_ECHELON_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Hitachi Echelon 1.5T
definition: Hitachi Echelon 1.5T MRI scanner
field strength: 1.5T
manufacturer: Hitachi

HITACHI_OASIS_1_2T
type: Class
subclass of: MRIPlatformEnum
alternative label: Hitachi Oasis 1.2T
definition: Hitachi Oasis 1.2T MRI scanner
field strength: 1.2T
manufacturer: Hitachi

PHILIPS_ACHIEVA_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Achieva 1.5T
definition: Philips Achieva 1.5T MRI scanner
field strength: 1.5T
manufacturer: Philips Healthcare

PHILIPS_ACHIEVA_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Achieva 3T
definition: Philips Achieva 3T MRI scanner
field strength: 3T
manufacturer: Philips Healthcare

PHILIPS_INGENIA_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Ingenia 1.5T
definition: Philips Ingenia 1.5T MRI scanner
field strength: 1.5T
manufacturer: Philips Healthcare

PHILIPS_INGENIA_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Ingenia 3T
definition: Philips Ingenia 3T MRI scanner
field strength: 3T
manufacturer: Philips Healthcare

PHILIPS_INTERA_ACHIEVA_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Intera Achieva 3T
definition: Philips Intera Achieva 3T MRI scanner
field strength: 3T
manufacturer: Philips Healthcare

PHILIPS_PANORAMA_1_0T
type: Class
subclass of: MRIPlatformEnum
alternative label: Philips Panorama 1.0T
definition: Philips Panorama 1.0T MRI scanner
field strength: 1.0T
manufacturer: Philips Healthcare

SIEMENS_AERA_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Aera 1.5T
definition: Siemens Magnetom Aera 1.5T MRI scanner
field strength: 1.5T
manufacturer: Siemens

SIEMENS_AVANTO_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Avanto 1.5T
definition: Siemens Magnetom Avanto 1.5T MRI scanner
field strength: 1.5T
manufacturer: Siemens

SIEMENS_AVANTO_FIT_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Avanto Fit 1.5T
definition: Siemens Magnetom Avanto Fit 1.5T MRI scanner
field strength: 1.5T
manufacturer: Siemens

SIEMENS_ESPREE_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Espree 1.5T
definition: Siemens Magnetom Espree 1.5T MRI scanner
field strength: 1.5T
manufacturer: Siemens

SIEMENS_PRISMA_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Prisma 3T
definition: Siemens Magnetom Prisma 3T MRI scanner
field strength: 3T
manufacturer: Siemens

SIEMENS_PRISMA_FIT_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Prisma Fit 3T
definition: Siemens Magnetom Prisma Fit 3T MRI scanner
field strength: 3T
manufacturer: Siemens

SIEMENS_SKYRA_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Skyra 3T
definition: Siemens Magnetom Skyra 3T MRI scanner
field strength: 3T
manufacturer: Siemens

SIEMENS_TRIO_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Trio 3T
definition: Siemens Magnetom Trio 3T MRI scanner
field strength: 3T
manufacturer: Siemens

SIEMENS_VERIO_3T
type: Class
subclass of: MRIPlatformEnum
alternative label: Siemens Magnetom Verio 3T
definition: Siemens Magnetom Verio 3T MRI scanner
field strength: 3T
manufacturer: Siemens

TOSHIBA_VANTAGE_TITAN_1_5T
type: Class
subclass of: MRIPlatformEnum
alternative label: Toshiba Vantage Titan 1.5T
definition: Toshiba Vantage Titan 1.5T MRI scanner
field strength: 1.5T
manufacturer: Toshiba/Canon

SPACE
type: Class
title: Sampling perfection with application optimized contrasts
subclass of: MRISequenceTypeEnum
definition: 3D turbo spin echo sequence
dimension: 3D
image type: T2-weighted
typical use: high-resolution T2 imaging

ANTIFERROMAGNETIC
type: Class
title: Antiferromagnetic
subclass of: MagneticPropertyEnum
definition: Adjacent magnetic moments cancel each other

DIAMAGNETIC
type: Class
title: Diamagnetic
subclass of: MagneticPropertyEnum
definition: Weakly repelled by magnetic fields

FERRIMAGNETIC
type: Class
title: Ferrimagnetic
subclass of: MagneticPropertyEnum
definition: Similar to ferromagnetic but with opposing magnetic moments

FERROMAGNETIC
type: Class
title: Ferromagnetic
subclass of: MagneticPropertyEnum
definition: Strongly attracted to magnetic fields, can be permanently magnetized

PARAMAGNETIC
type: Class
title: Paramagnetic
subclass of: MagneticPropertyEnum
definition: Weakly attracted to magnetic fields

CONDITION_BASED_MAINTENANCE
type: Class
title: Condition-Based Maintenance
subclass of: MaintenanceTypeEnum
definition: Maintenance triggered by equipment condition assessment
assessment: continuous condition monitoring
optimization: resource optimization
safety: maintains safety margins
trigger: condition degradation

CORRECTIVE_MAINTENANCE
type: Class
title: Corrective Maintenance
subclass of: MaintenanceTypeEnum
definition: Maintenance to repair failed or degraded equipment
planning: may be immediate
schedule: unplanned
trigger: equipment failure or degradation
urgency: varies by safety significance

FORCED_OUTAGE_MAINTENANCE
type: Class
title: Forced Outage Maintenance
subclass of: MaintenanceTypeEnum
definition: Unplanned maintenance due to equipment failure
cause: unexpected equipment failure
duration: variable
safety significance: may affect safety systems
urgency: immediate attention required

IN_SERVICE_INSPECTION
type: Class
title: In-Service Inspection
subclass of: MaintenanceTypeEnum
definition: Required inspection of safety-related components
frequency: specified intervals (typically 10 years)
regulatory requirement: mandated by regulations
scope: pressure vessels, piping, supports
techniques: non-destructive testing

MODIFICATION_WORK
type: Class
title: Modification Work
subclass of: MaintenanceTypeEnum
definition: Changes to plant design or configuration
approval: requires design change approval
documentation: comprehensive documentation updates
purpose: plant improvement or regulatory compliance
testing: extensive post-modification testing

PREDICTIVE_MAINTENANCE
type: Class
title: Predictive Maintenance
subclass of: MaintenanceTypeEnum
definition: Maintenance based on condition monitoring
basis: condition monitoring data
efficiency: optimized maintenance timing
technology: condition monitoring systems
timing: based on predicted failure

PREVENTIVE_MAINTENANCE
type: Class
title: Preventive Maintenance
subclass of: MaintenanceTypeEnum
definition: Scheduled maintenance to prevent equipment failure
outage type: planned outage
planning: extensive advance planning
purpose: prevent failures
schedule: predetermined intervals

REFUELING_OUTAGE_MAINTENANCE
type: Class
title: Refueling Outage Maintenance
subclass of: MaintenanceTypeEnum
definition: Major maintenance during scheduled refueling
access: full plant access available
duration: 30-60 days typical
frequency: every 12-24 months
scope: major equipment inspection and repair

BOARD_OF_DIRECTORS
type: Class
title: Board of Directors
subclass of: ManagementLevelEnum
definition: Governing body elected by shareholders
authority: highest governance authority
composition: independent and inside directors
oversight: strategic oversight and control
responsibility: fiduciary responsibility to shareholders

C_SUITE
type: Class
title: C-Suite/Chief Officers
subclass of: ManagementLevelEnum
definition: Top executive leadership team
accountability: accountable to board of directors
level: top executive level
scope: organization-wide responsibility
titles: CEO, CFO, COO, CTO, etc.

DIRECTOR
type: Class
title: Director
subclass of: ManagementLevelEnum
definition: Management responsible for departments or major programs
level: middle management
oversight: manages multiple managers
responsibility: departmental leadership
scope: department or program

ENTRY_LEVEL
type: Class
title: Entry Level
subclass of: ManagementLevelEnum
definition: Beginning professional or support roles
development: learning and development focus
experience: minimal professional experience
growth potential: career growth opportunities
supervision: close supervision

INDIVIDUAL_CONTRIBUTOR
type: Class
title: Individual Contributor
subclass of: ManagementLevelEnum
definition: Professional or specialist role
career path: professional career track
level: professional
responsibility: individual work output
specialization: functional specialization

MANAGER
type: Class
title: Manager
subclass of: ManagementLevelEnum
definition: Supervisory role managing teams or operations
level: middle management
responsibility: day-to-day operations
scope: team or operational unit
supervision: manages individual contributors

SENIOR_EXECUTIVE
type: Class
title: Senior Executive
subclass of: ManagementLevelEnum
definition: Senior leadership below C-suite level
level: senior leadership
reporting: reports to C-suite
scope: major business unit or function
titles: EVP, SVP, General Manager

SENIOR_INDIVIDUAL_CONTRIBUTOR
type: Class
title: Senior Individual Contributor
subclass of: ManagementLevelEnum
definition: Experienced professional without management responsibilities
expertise: specialized expertise
level: senior professional
mentoring: may mentor junior staff
projects: leads complex projects

SUPERVISOR
type: Class
title: Supervisor
subclass of: ManagementLevelEnum
definition: First-line management overseeing frontline employees
interface: employee-management interface
level: first-line management
responsibility: direct supervision
scope: small team or shift

TEAM_LEAD
type: Class
title: Team Lead
subclass of: ManagementLevelEnum
definition: Lead role within team without formal management authority
authority: informal authority
expertise: technical or project leadership
level: senior individual contributor
responsibility: team coordination

VICE_PRESIDENT
type: Class
title: Vice President
subclass of: ManagementLevelEnum
definition: Senior management responsible for major divisions
authority: significant decision-making authority
level: senior management
scope: division or major function
titles: VP, Assistant VP

AGILE_MANAGEMENT
type: Class
title: Agile Management
subclass of: ManagementMethodologyEnum
definition: Flexible, iterative management approach
collaboration: cross-functional collaboration
customer focus: customer-centric
flexibility: adaptive and flexible
iteration: iterative approach

DEMOCRATIC_MANAGEMENT
type: Class
title: Democratic Management
subclass of: ManagementMethodologyEnum
definition: Collaborative and consensus-building approach
consensus: consensus-building
equality: equal voice in decisions
participation: democratic participation
transparency: transparent processes

LEAN_MANAGEMENT
type: Class
title: Lean Management
subclass of: ManagementMethodologyEnum
definition: Waste elimination and value optimization approach
continuous improvement: kaizen and continuous improvement
efficiency: operational efficiency
focus: waste elimination
value: value stream optimization

MATRIX_MANAGEMENT
type: Class
title: Matrix Management
subclass of: ManagementMethodologyEnum
definition: Dual reporting relationships and shared authority
authority: shared authority
complexity: increased complexity
flexibility: organizational flexibility
structure: matrix reporting structure

PARTICIPATIVE_MANAGEMENT
type: Class
title: Participative Management
subclass of: ManagementMethodologyEnum
definition: Employee involvement in decision-making
decision making: shared decision-making
empowerment: employee empowerment
engagement: increased employee engagement
involvement: employee participation

PROJECT_MANAGEMENT
type: Class
title: Project Management
subclass of: ManagementMethodologyEnum
definition: Structured approach to managing projects
deliverables: deliverable-focused
lifecycle: project lifecycle management
methodology: project management methodology
temporary: temporary organizational structure

RESULTS_ORIENTED_MANAGEMENT
type: Class
title: Results-Oriented Management
subclass of: ManagementMethodologyEnum
definition: Focus on outcomes and performance results
accountability: accountability for results
focus: results and outcomes
goals: goal-oriented approach
measurement: performance measurement

SERVANT_LEADERSHIP
type: Class
title: Servant Leadership
subclass of: ManagementMethodologyEnum
definition: Leader serves and supports team members
development: people development focus
empowerment: team empowerment
philosophy: service-oriented leadership
support: leader supports team

TRADITIONAL_MANAGEMENT
type: Class
title: Traditional Management
subclass of: ManagementMethodologyEnum
definition: Hierarchical command-and-control management approach
authority: centralized authority
communication: top-down communication
control: direct supervision and control
structure: hierarchical structure

TRANSFORMATIONAL_MANAGEMENT
type: Class
title: Transformational Management
subclass of: ManagementMethodologyEnum
definition: Change-oriented and inspirational management
change: transformation and change focus
development: follower development
inspiration: inspirational leadership
vision: vision-driven

ADDITIVE_MANUFACTURING
type: Class
subclass of: ManufacturingProcessType
definition: Manufacturing by adding material layer by layer to build a three-dimensional object

CASTING
type: Class
subclass of: ManufacturingProcessType
definition: Pouring molten material into a mold and allowing it to solidify

ELECTROFORMING
type: Class
subclass of: ManufacturingProcessType
broad match: CHMO_0001331
definition: Producing metal parts by electrodeposition of metal onto a mandrel or pattern

FORGING
type: Class
subclass of: ManufacturingProcessType
definition: Shaping metal using compressive forces applied by hammering, pressing, or rolling

FORMATIVE_MANUFACTURING
type: Class
subclass of: ManufacturingProcessType
definition: Manufacturing by reshaping material through mechanical forces without significant addition or removal

MACHINING
type: Class
subclass of: ManufacturingProcessType
definition: Removing material from a workpiece using cutting tools to achieve a desired geometry

POWDER_METALLURGY
type: Class
subclass of: ManufacturingProcessType
broad match: CHMO_0001701
definition: Forming metal parts from compacted and sintered metal powders

SUBTRACTIVE_MANUFACTURING
type: Class
subclass of: ManufacturingProcessType
definition: Manufacturing by removing material from a solid block to create a desired shape

WELDING
type: Class
subclass of: ManufacturingProcessType
definition: Joining materials by applying heat, pressure, or both to fuse them together

ManufacturingSchemaEnum
type: Class
subclass of: IndustryDomainEnum
definition: Schema-level enum for manufacturing in industry
in scheme: merged
source file: industry/manufacturing.yaml

BOX
type: Class
subclass of: ManuscriptSection
definition: Box/Sidebar with supplementary information
placement: variable

CONSORT_FLOW_DIAGRAM
type: Class
subclass of: ManuscriptSection
definition: CONSORT flow diagram
specific to: randomized trials

GLOSSARY
type: Class
subclass of: ManuscriptSection
definition: Glossary of terms
placement: front or back matter

HIGHLIGHTS
type: Class
subclass of: ManuscriptSection
definition: Highlights/Key points
order: 3.5e+00
typical length: 3-5 bullet points

META_ANALYSIS
type: Class
subclass of: ManuscriptSection
definition: Meta-analysis section
specific to: meta-analyses

OTHER_MAIN_TEXT
type: Class
subclass of: ManuscriptSection
definition: Other main text section
catch all: true

OTHER_SUPPLEMENTARY
type: Class
subclass of: ManuscriptSection
definition: Other supplementary section
catch all: true

RESULTS_AND_DISCUSSION
type: Class
subclass of: ManuscriptSection
definition: Combined Results and Discussion
note: alternative to separate sections
order: 8

STUDY_PROTOCOL
type: Class
subclass of: ManuscriptSection
definition: Study protocol
specific to: clinical trials

SYSTEMATIC_REVIEW_METHODS
type: Class
subclass of: ManuscriptSection
definition: Systematic review methodology (PRISMA)
specific to: systematic reviews

DUOPOLY
type: Class
title: Duopoly
subclass of: MarketStructureEnum
definition: Two firms dominating the market
barriers: high barriers to entry
competition: head-to-head competition
competitors: two dominant competitors
examples: aircraft manufacturing, some software markets
strategy: strategic competition

MONOPOLISTIC_COMPETITION
type: Class
title: Monopolistic Competition
subclass of: MarketStructureEnum
definition: Many firms with differentiated products
barriers: low barriers to entry
competitors: many competitors
examples: restaurants, retail clothing
pricing: some pricing power
products: differentiated products

MONOPOLY
type: Class
title: Monopoly
subclass of: MarketStructureEnum
definition: Single firm controlling the market
barriers: very high barriers to entry
competitors: single market leader
examples: utilities, patented products
pricing: price maker
regulation: often regulated

OLIGOPOLY
type: Class
title: Oligopoly
subclass of: MarketStructureEnum
definition: Few large firms dominating the market
barriers: significant barriers to entry
competitors: few large competitors
concentration: high market concentration
examples: automobiles, telecommunications
interdependence: strategic interdependence

PERFECT_COMPETITION
type: Class
title: Perfect Competition
subclass of: MarketStructureEnum
definition: Many small firms with identical products
barriers: no barriers to entry
competitors: many small competitors
examples: agricultural commodities
pricing: price takers
products: homogeneous products

MassErrorUnit
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Mass Error Unit
status: DRAFT
subclass of: ProteomicsStandardsSchemaEnum
union of: PPM
union of: DA
definition: Units for expressing mass error in mass spectrometry
in scheme: merged
permissible values: DA
permissible values: PPM
source domain: bio
source schema: proteomics_standards

DA
type: Class
subclass of: MassErrorUnit
alternative label: Dalton
alternative label: amu
alternative label: u
definition: Dalton - absolute mass error

PPM
type: Class
subclass of: MassErrorUnit
definition: Parts per million - relative mass error

FIA_MSMS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: FIA-MSMS
definition: Flow injection analysis tandem mass spectrometry

HPLC_MS_MS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: high-performance liquid chromatography/tandem mass spectrometry
definition: High-performance liquid chromatography/tandem mass spectrometry

LABEL_FREE_MS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: label free mass spectrometry
definition: Label-free mass spectrometry quantification

LC_ECD
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: liquid chromatography-electrochemical detection
definition: Liquid chromatography-electrochemical detection

MIB_MS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: MIB/MS
definition: Multiplexed Inhibitor Beads mass spectrometry

MUDPIT
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: MudPIT
definition: Multidimensional Protein Identification Technology

PROXIMITY_EXTENSION_ASSAY
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: PEA
definition: Proximity extension assay

TMT_QUANTITATION
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: TMT quantitation
definition: Tandem mass tag quantitation

UHPLC_MS_MS
type: Class
subclass of: MassSpectrometryAssayEnum
alternative label: ultra high-performance liquid chromatography/tandem mass spectrometry
definition: Ultra high-performance liquid chromatography/tandem mass spectrometry

BAND_GAP
type: Class
subclass of: MaterialPropertyPredictionType
definition: Energy difference between the valence band and conduction band in a semiconductor or insulator

DEFECT_ENERGY
type: Class
subclass of: MaterialPropertyPredictionType
definition: Energy associated with the formation or migration of point defects and dislocations

DIELECTRIC_CONSTANT
type: Class
subclass of: MaterialPropertyPredictionType
definition: Ratio of the permittivity of a material to the permittivity of free space

ELASTIC_MODULUS
type: Class
subclass of: MaterialPropertyPredictionType
broad match: PATO_0001031
definition: Measure of material stiffness defined as the ratio of stress to strain in the elastic regime

FORMATION_ENERGY
type: Class
subclass of: MaterialPropertyPredictionType
definition: Energy required to form a compound from its constituent elements in their standard states

MAGNETIC_MOMENT
type: Class
subclass of: MaterialPropertyPredictionType
definition: Magnetic dipole moment of a material arising from electron spin and orbital contributions

MECHANICAL_STRENGTH
type: Class
subclass of: MaterialPropertyPredictionType
broad match: PATO_0001230
definition: Maximum stress a material can withstand before failure under applied load

PHASE_STABILITY
type: Class
subclass of: MaterialPropertyPredictionType
definition: Thermodynamic stability of a material phase relative to competing phases

SURFACE_ENERGY
type: Class
subclass of: MaterialPropertyPredictionType
definition: Excess energy at the surface of a material relative to its bulk

AB_INITIO_MOLECULAR_DYNAMICS
type: Class
subclass of: MaterialsSimulationType
definition: Molecular dynamics with forces computed from first-principles electronic structure calculations

COARSE_GRAINED_SIMULATION
type: Class
subclass of: MaterialsSimulationType
definition: Simulation using simplified representations that group atoms into larger effective interaction sites

CONTINUUM_MECHANICS
type: Class
subclass of: MaterialsSimulationType
definition: Modeling material behavior at the macroscopic scale using continuous field equations

DENSITY_FUNCTIONAL_THEORY
type: Class
subclass of: MaterialsSimulationType
definition: Quantum mechanical method for computing electronic structure based on electron density functionals

FINITE_ELEMENT_ANALYSIS
type: Class
subclass of: MaterialsSimulationType
definition: Numerical method for solving partial differential equations by dividing a domain into discrete elements

MACHINE_LEARNING_POTENTIAL
type: Class
subclass of: MaterialsSimulationType
definition: Interatomic potentials trained on quantum mechanical data using machine learning methods

PHASE_FIELD_MODELING
type: Class
subclass of: MaterialsSimulationType
definition: Continuum method for simulating microstructure evolution using order parameter fields

TIGHT_BINDING
type: Class
subclass of: MaterialsSimulationType
definition: Semi-empirical quantum mechanical method using parameterized Hamiltonian matrices

DUCTILE
type: Class
title: Ductile
subclass of: MechanicalBehaviorEnum
definition: Can be drawn into wires, undergoes large plastic deformation

MALLEABLE
type: Class
title: Malleable
subclass of: MechanicalBehaviorEnum
definition: Can be hammered into sheets

TOUGH
type: Class
title: Tough
subclass of: MechanicalBehaviorEnum
definition: High resistance to fracture

VISCOELASTIC
type: Class
title: Viscoelastic
subclass of: MechanicalBehaviorEnum
definition: Exhibits both viscous and elastic characteristics

COMPRESSION
type: Class
title: Compression Test
subclass of: MechanicalTestingMethodEnum
definition: Compression strength testing

CREEP
type: Class
title: Creep Test
subclass of: MechanicalTestingMethodEnum
definition: Creep testing under sustained load

FATIGUE
type: Class
title: Fatigue Test
subclass of: MechanicalTestingMethodEnum
definition: Fatigue testing under cyclic loading

FRACTURE_TOUGHNESS
type: Class
title: Fracture Toughness
subclass of: MechanicalTestingMethodEnum
definition: Fracture toughness testing

HARDNESS
type: Class
title: Hardness Test
subclass of: MechanicalTestingMethodEnum
definition: Hardness testing (Vickers, Rockwell, Brinell)

IMPACT
type: Class
title: Impact Test
subclass of: MechanicalTestingMethodEnum
definition: Impact resistance testing (Charpy, Izod)

NANOINDENTATION
type: Class
title: Nanoindentation
subclass of: MechanicalTestingMethodEnum
definition: Nanoindentation for nanoscale mechanical properties

TENSILE
type: Class
title: Tensile Test
subclass of: MechanicalTestingMethodEnum
definition: Tensile strength testing

ANESTHESIOLOGY
type: Class
title: Anesthesia and perioperative medicine
subclass of: MedicalSpecialtyEnum

CARDIOLOGY
type: Class
title: Heart and cardiovascular diseases
subclass of: MedicalSpecialtyEnum

DERMATOLOGY
type: Class
title: Skin diseases
subclass of: MedicalSpecialtyEnum

EMERGENCY_MEDICINE
type: Class
title: Emergency and acute care
subclass of: MedicalSpecialtyEnum

ENDOCRINOLOGY
type: Class
title: Hormonal and metabolic disorders
subclass of: MedicalSpecialtyEnum

FAMILY_MEDICINE
type: Class
title: Primary care for all ages
subclass of: MedicalSpecialtyEnum

GASTROENTEROLOGY
type: Class
title: Digestive system disorders
subclass of: MedicalSpecialtyEnum

HEMATOLOGY
type: Class
title: Blood disorders
subclass of: MedicalSpecialtyEnum

INFECTIOUS_DISEASE
type: Class
title: Infectious diseases
subclass of: MedicalSpecialtyEnum

INTERNAL_MEDICINE
type: Class
title: Adult internal medicine
subclass of: MedicalSpecialtyEnum

NEPHROLOGY
type: Class
title: Kidney diseases
subclass of: MedicalSpecialtyEnum

NEUROLOGY
type: Class
title: Nervous system disorders
subclass of: MedicalSpecialtyEnum

OBSTETRICS_GYNECOLOGY
type: Class
title: Women's health and childbirth
subclass of: MedicalSpecialtyEnum

ONCOLOGY
type: Class
title: Cancer treatment
subclass of: MedicalSpecialtyEnum

OPHTHALMOLOGY
type: Class
title: Eye diseases
subclass of: MedicalSpecialtyEnum

ORTHOPEDICS
type: Class
title: Musculoskeletal disorders
subclass of: MedicalSpecialtyEnum

OTOLARYNGOLOGY
type: Class
title: Ear, nose, and throat
subclass of: MedicalSpecialtyEnum

PATHOLOGY
type: Class
title: Disease diagnosis through lab analysis
subclass of: MedicalSpecialtyEnum

PEDIATRICS
type: Class
title: Children's health
subclass of: MedicalSpecialtyEnum

PSYCHIATRY
type: Class
title: Mental health disorders
subclass of: MedicalSpecialtyEnum

PULMONOLOGY
type: Class
title: Lung and respiratory diseases
subclass of: MedicalSpecialtyEnum

RADIOLOGY
type: Class
title: Medical imaging
subclass of: MedicalSpecialtyEnum

RHEUMATOLOGY
type: Class
title: Joint and autoimmune diseases
subclass of: MedicalSpecialtyEnum

SURGERY
type: Class
title: Surgical procedures
subclass of: MedicalSpecialtyEnum

UROLOGY
type: Class
title: Urinary and male reproductive system
subclass of: MedicalSpecialtyEnum

MetalLigandType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: Metal Ligand Type
status: DRAFT
subclass of: StructuralBiologySchemaEnum
union of: METAL_CATION
union of: METAL_CONTAINING_LIGAND
definition: Types of metal-containing chemical components
in scheme: merged
permissible values: METAL_CATION
permissible values: METAL_CONTAINING_LIGAND
source domain: bio
source schema: structural_biology

METAL_CATION
type: Class
subclass of: MetalLigandType
definition: Metal cation (e.g., Ca2+, Mg2+, Zn2+, Fe3+)
examples: Ca2+, Mg2+, Zn2+, Fe2+, Fe3+, Cu2+, Mn2+

METAL_CONTAINING_LIGAND
type: Class
subclass of: MetalLigandType
definition: Metal-containing ligand or cofactor
examples: heme, chlorophyll, cobalamin, Fe-S cluster

NOBLE_METAL
type: Class
title: Noble Metal
subclass of: MetalTypeEnum
definition: Metals resistant to corrosion and oxidation

REFRACTORY_METAL
type: Class
title: Refractory Metal
subclass of: MetalTypeEnum
definition: Metals with very high melting points (>2000°C)

MicroelectronicsSchemaEnum
type: Class
subclass of: ComputingDomainEnum
definition: Schema-level enum for microelectronics in computing
in scheme: merged
source file: computing/microelectronics.yaml

WELL_12
type: Class
title: 12-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 12 wells

WELL_1536
type: Class
title: 1536-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 1536 wells with 2.25mm well-to-well spacing
standard: ANSI/SLAS 4-2004
well spacing: 2.25mm

WELL_24
type: Class
title: 24-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 24 wells

WELL_384
type: Class
title: 384-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 384 wells with 4.5mm well-to-well spacing
standard: ANSI/SLAS 4-2004
well spacing: 4.5mm

WELL_48
type: Class
title: 48-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 48 wells

WELL_6
type: Class
title: 6-well plate
subclass of: MicroplateFormatEnum
definition: Microplate with 6 wells

STEM
type: Class
subclass of: MicroscopyMethodEnum
alternative label: Scanning Transmission Electron Microscopy
definition: Scanning Transmission Electron Microscopy

APERIO_CS2
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Aperio CS2
definition: Aperio CS2 slide scanner
manufacturer: Leica
type: slide scanner

ECHO_CONFOCAL
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: ECHO Confocal
definition: ECHO confocal imaging system
type: confocal

LEICA_APERIO_AT2
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Leica Aperio AT2
definition: Leica Aperio AT2 whole slide scanner
manufacturer: Leica
type: slide scanner

LEICA_MZ16
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Leica MZ16
definition: Leica MZ16 stereomicroscope
manufacturer: Leica
type: stereomicroscope

LEICA_S9
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Leica S9 Stereomicroscope
definition: Leica S9 stereomicroscope
manufacturer: Leica
type: stereomicroscope

OLYMPUS_DP80
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Olympus DP80
definition: Olympus DP80 camera system
manufacturer: Olympus
type: camera

OLYMPUS_IX73
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Olympus IX73
definition: Olympus IX73 inverted microscope
manufacturer: Olympus
type: inverted fluorescence

PANNORAMIC_250_FLASH
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Pannoramic 250 Flash
definition: 3DHISTECH Pannoramic 250 Flash slide scanner
manufacturer: 3DHISTECH
type: slide scanner

PHILIPS_FEI_TECNAI_12
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Philips FEI Tecnai 12
definition: Philips FEI Tecnai 12 electron microscope
manufacturer: FEI/Thermo Fisher
type: TEM

ZEISS_LSM
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Zeiss LSM
definition: Zeiss LSM confocal microscope (general)
manufacturer: Zeiss
type: confocal

ZEISS_LSM_700
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Zeiss LSM 700
definition: Zeiss LSM 700 confocal microscope
manufacturer: Zeiss
type: confocal

ZEISS_LSM_980
type: Class
subclass of: MicroscopyPlatformEnum
alternative label: Zeiss LSM 980
definition: Zeiss LSM 980 confocal microscope
manufacturer: Zeiss
type: confocal

APPLICATION
type: Class
subclass of: MimeTypeCategory
definition: Application data

AUDIO
type: Class
subclass of: MimeTypeCategory
definition: Audio files

FONT
type: Class
subclass of: MimeTypeCategory
definition: Font files

IMAGE
type: Class
subclass of: MimeTypeCategory
definition: Image files

MESSAGE
type: Class
subclass of: MimeTypeCategory
definition: Message formats

MODEL
type: Class
subclass of: MimeTypeCategory
definition: 3D models and similar

MULTIPART
type: Class
subclass of: MimeTypeCategory
definition: Multipart messages

TEXT
type: Class
subclass of: MimeTypeCategory
definition: Text documents

VIDEO
type: Class
subclass of: MimeTypeCategory
definition: Video files

BASE_METALS
type: Class
subclass of: MineralCategory
definition: Base metals
examples: copper, lead, zinc, tin

CHEMICAL_MINERALS
type: Class
subclass of: MineralCategory
definition: Chemical and fertilizer minerals
examples: phosphate, potash, sulfur

CONSTRUCTION_MATERIALS
type: Class
subclass of: MineralCategory
definition: Construction materials
examples: sand, gravel, crushed stone

ENERGY_MINERALS
type: Class
subclass of: MineralCategory
definition: Energy minerals
examples: coal, oil shale, tar sands

FERROUS_METALS
type: Class
subclass of: MineralCategory
definition: Ferrous metals
examples: iron, steel, manganese

GEMSTONES
type: Class
subclass of: MineralCategory
definition: Gemstones
examples: diamond, ruby, emerald

INDUSTRIAL_MINERALS
type: Class
subclass of: MineralCategory
definition: Industrial minerals
examples: limestone, gypsum, salt

PRECIOUS_METALS
type: Class
subclass of: MineralCategory
definition: Precious metals
examples: gold, silver, platinum

RADIOACTIVE
type: Class
subclass of: MineralCategory
definition: Radioactive minerals
examples: uranium, thorium, radium

RARE_EARTH_ELEMENTS
type: Class
subclass of: MineralCategory
definition: Rare earth elements
count: 17 elements
examples: neodymium, dysprosium, cerium

BRINES
type: Class
subclass of: MineralogyFeedstockClass
definition: Saline water sources containing dissolved minerals

COAL_BYPRODUCT
type: Class
subclass of: MineralogyFeedstockClass
definition: Byproducts from coal mining and processing

E_WASTE
type: Class
subclass of: MineralogyFeedstockClass
definition: Electronic waste containing recoverable metals

HARDROCK_PRIMARY
type: Class
subclass of: MineralogyFeedstockClass
definition: Primary ore from hardrock mining operations

TAILINGS_LEGACY
type: Class
subclass of: MineralogyFeedstockClass
definition: Historical mine tailings available for reprocessing

WASTE_PILES
type: Class
subclass of: MineralogyFeedstockClass
definition: Accumulated mining waste materials

BALL_MILL
type: Class
subclass of: MiningEquipment
definition: Ball mill
category: processing
use: grinding

BUCKET_WHEEL_EXCAVATOR
type: Class
subclass of: MiningEquipment
definition: Bucket-wheel excavator
category: excavation
use: continuous mining

CONTINUOUS_MINER
type: Class
subclass of: MiningEquipment
definition: Continuous miner
category: underground

CONVEYOR
type: Class
subclass of: MiningEquipment
definition: Conveyor system
category: transport

CRUSHER
type: Class
subclass of: MiningEquipment
definition: Crusher
category: processing
types: jaw, cone, impact

DRAGLINE
type: Class
subclass of: MiningEquipment
definition: Dragline excavator
category: excavation
size: large-scale

DRILL_RIG
type: Class
subclass of: MiningEquipment
definition: Drilling rig
category: drilling

EXCAVATOR
type: Class
subclass of: MiningEquipment
definition: Excavator
category: excavation

FLOTATION_CELL
type: Class
subclass of: MiningEquipment
definition: Flotation cell
category: processing
use: mineral separation

HAUL_TRUCK
type: Class
subclass of: MiningEquipment
definition: Haul truck
capacity: up to 400 tons
category: hauling

JUMBO_DRILL
type: Class
subclass of: MiningEquipment
definition: Jumbo drill
category: drilling
use: underground

LOADER
type: Class
subclass of: MiningEquipment
definition: Loader
category: loading

ROOF_BOLTER
type: Class
subclass of: MiningEquipment
definition: Roof bolter
category: underground
use: support installation

SHUTTLE_CAR
type: Class
subclass of: MiningEquipment
definition: Shuttle car
category: underground transport

CAVE_IN
type: Class
subclass of: MiningHazard
definition: Cave-in/roof collapse
type: structural

CHEMICAL_EXPOSURE
type: Class
subclass of: MiningHazard
definition: Chemical exposure
chemicals: mercury, cyanide, acids
type: toxic

DUST_EXPOSURE
type: Class
subclass of: MiningHazard
definition: Dust exposure
diseases: silicosis, pneumoconiosis
type: respiratory

EQUIPMENT_ACCIDENT
type: Class
subclass of: MiningHazard
definition: Equipment-related accident
type: mechanical

FLOODING
type: Class
subclass of: MiningHazard
definition: Mine flooding
type: water

GAS_EXPLOSION
type: Class
subclass of: MiningHazard
definition: Gas explosion
gases: methane, coal dust
type: chemical

HEAT_STRESS
type: Class
subclass of: MiningHazard
definition: Heat stress
type: thermal

NOISE
type: Class
subclass of: MiningHazard
definition: Noise exposure
type: physical

RADIATION
type: Class
subclass of: MiningHazard
definition: Radiation exposure
source: uranium, radon
type: radioactive

VIBRATION
type: Class
subclass of: MiningHazard
definition: Vibration exposure
type: physical

IN_SITU
type: Class
title: In Situ
subclass of: MiningMethodEnum
definition: Extraction without removing the ore from its original location

OPEN_PIT
type: Class
title: Open Pit
subclass of: MiningMethodEnum
definition: Extraction occurs on the earth's surface

PLACER
type: Class
title: Placer
subclass of: MiningMethodEnum
definition: Extraction of valuable minerals from alluvial deposits

UNDERGROUND
type: Class
title: Underground
subclass of: MiningMethodEnum
definition: Extraction occurs beneath the earth's surface

CLOSURE
type: Class
subclass of: MiningPhase
definition: Closure phase
activities: decommissioning, capping

DEVELOPMENT
type: Class
subclass of: MiningPhase
definition: Development phase
activities: infrastructure, access roads

EXPLORATION
type: Class
subclass of: MiningPhase
definition: Exploration phase
activities: prospecting, sampling, drilling

POST_CLOSURE
type: Class
subclass of: MiningPhase
definition: Post-closure monitoring
activities: long-term monitoring

PROCESSING
type: Class
subclass of: MiningPhase
definition: Processing/beneficiation phase
activities: crushing, milling, concentration

PRODUCTION
type: Class
subclass of: MiningPhase
definition: Production/extraction phase
activities: active mining

RECLAMATION
type: Class
subclass of: MiningPhase
definition: Reclamation phase
activities: restoration, revegetation

ARTISANAL
type: Class
subclass of: MiningType
definition: Artisanal and small-scale mining
category: small-scale
equipment: minimal mechanization

BLOCK_CAVING
type: Class
subclass of: MiningType
definition: Block caving
category: underground
method: gravity-assisted

DEEP_SEA
type: Class
subclass of: MiningType
definition: Deep sea mining
category: marine
depth: ocean floor

DREDGING
type: Class
subclass of: MiningType
definition: Dredging
category: surface/underwater
environment: rivers, harbors, seas

DRIFT_MINING
type: Class
subclass of: MiningType
definition: Drift mining
access: horizontal tunnel
category: underground

HYDRAULIC_MINING
type: Class
subclass of: MiningType
definition: Hydraulic mining
category: specialized
method: high-pressure water

LONGWALL
type: Class
subclass of: MiningType
definition: Longwall mining
category: underground
method: progressive slice extraction

MOUNTAINTOP_REMOVAL
type: Class
subclass of: MiningType
definition: Mountaintop removal mining
category: surface
region: primarily Appalachian

ROOM_AND_PILLAR
type: Class
subclass of: MiningType
definition: Room and pillar mining
category: underground
method: leaves pillars for support

SHAFT_MINING
type: Class
subclass of: MiningType
definition: Shaft mining
access: vertical shaft
category: underground

SLOPE_MINING
type: Class
subclass of: MiningType
definition: Slope mining
access: inclined shaft
category: underground

SOLUTION_MINING
type: Class
subclass of: MiningType
definition: Solution mining (in-situ leaching)
category: specialized
method: chemical dissolution

C_ELEGANS_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: C. elegans disease model

DROSOPHILA_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: Drosophila (fruit fly) disease model

GEMM
type: Class
subclass of: ModelSystemTypeEnum
alternative label: genetically engineered mouse model
definition: Genetically engineered mouse model

KNOCKIN_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: Gene knock-in animal model

YEAST_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: Yeast genetic model

ZEBRAFISH_MODEL
type: Class
subclass of: ModelSystemTypeEnum
definition: Zebrafish disease model

THEILER_STAGE
type: Class
subclass of: MouseDevelopmentalStage
definition: Reference to any Theiler stage (TS1-TS28) which provides standardized morphological staging for mouse development.

P0_P3_NEONATAL
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P0-P3 Neonatal
definition: Neonatal stage from birth through postnatal day 3
approximate age: birth to day 3
postnatal days: P0-P3

P180_P365_MIDDLE_AGED
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P180-P365 Middle-Aged
definition: Middle-aged stage from postnatal days 180-365 (6 to 12 months)
approximate age: 6 to 12 months
postnatal days: P180-P365

P21_P60_YOUNG_ADULT
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P21-P60 Young Adult
definition: Young adult stage from postnatal days 21-60 (3 weeks to 2 months)
approximate age: 3 weeks to 2 months
postnatal days: P21-P60

P365_PLUS_AGED
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P365+ Aged
definition: Aged stage from postnatal day 365 onwards (12+ months)
approximate age: 12+ months
postnatal days: P365+

P4_P21_PREWEANING
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P4-P21 Pre-weaning
definition: Pre-weaning stage from postnatal days 4-21 (typical weaning age)
approximate age: days 4-21
postnatal days: P4-P21

P60_P180_ADULT
type: Class
subclass of: MousePostnatalAgeGroupEnum
alternative label: P60-P180 Adult
definition: Adult stage from postnatal days 60-180 (2 to 6 months)
approximate age: 2 to 6 months
postnatal days: P60-P180

SECTOR_11
type: Class
title: Agriculture, Forestry, Fishing and Hunting
subclass of: NAICSSectorEnum
definition: Establishments engaged in agriculture, forestry, fishing, and hunting
activities: crop production, animal production, forestry, fishing
economic base: natural resource extraction and production
naics code: 11

SECTOR_21
type: Class
title: Mining, Quarrying, and Oil and Gas Extraction
subclass of: NAICSSectorEnum
definition: Establishments engaged in extracting natural resources
activities: oil and gas extraction, mining, support activities
economic base: natural resource extraction
naics code: 21

SECTOR_22
type: Class
title: Utilities
subclass of: NAICSSectorEnum
definition: Establishments engaged in providing utilities
activities: electric power, natural gas, water, sewage, waste management
naics code: 22
regulation: heavily regulated

SECTOR_23
type: Class
title: Construction
subclass of: NAICSSectorEnum
definition: Establishments engaged in construction activities
activities: building construction, heavy construction, specialty trade contractors
cyclical: highly cyclical industry
naics code: 23

SECTOR_31_33
type: Class
title: Manufacturing
subclass of: NAICSSectorEnum
definition: Establishments engaged in manufacturing goods
activities: food, chemicals, machinery, transportation equipment
naics code: 31-33
value added: transforms materials into finished goods

SECTOR_42
type: Class
title: Wholesale Trade
subclass of: NAICSSectorEnum
definition: Establishments engaged in wholesale distribution
activities: merchant wholesalers, agents and brokers
function: intermediary between manufacturers and retailers
naics code: 42

SECTOR_44_45
type: Class
title: Retail Trade
subclass of: NAICSSectorEnum
definition: Establishments engaged in retail sales to consumers
activities: motor vehicle dealers, food stores, general merchandise
customer: sells to final consumers
naics code: 44-45

SECTOR_48_49
type: Class
title: Transportation and Warehousing
subclass of: NAICSSectorEnum
definition: Establishments providing transportation and warehousing services
activities: air, rail, water, truck transportation, warehousing
infrastructure: transportation infrastructure dependent
naics code: 48-49

SECTOR_51
type: Class
title: Information
subclass of: NAICSSectorEnum
definition: Establishments in information industries
activities: publishing, broadcasting, telecommunications, data processing
naics code: 51
technology: information technology and content

SECTOR_52
type: Class
title: Finance and Insurance
subclass of: NAICSSectorEnum
definition: Establishments providing financial services
activities: banking, securities, insurance, funds and trusts
naics code: 52
regulation: highly regulated financial sector

SECTOR_53
type: Class
title: Real Estate and Rental and Leasing
subclass of: NAICSSectorEnum
definition: Establishments engaged in real estate and rental activities
activities: real estate, rental and leasing services
asset type: real and personal property
naics code: 53

SECTOR_54
type: Class
title: Professional, Scientific, and Technical Services
subclass of: NAICSSectorEnum
definition: Establishments providing professional services
activities: legal, accounting, engineering, consulting, research
knowledge based: knowledge and skill intensive
naics code: 54

SECTOR_55
type: Class
title: Management of Companies and Enterprises
subclass of: NAICSSectorEnum
definition: Establishments serving as holding companies or managing enterprises
activities: holding companies, corporate management
function: corporate ownership and management
naics code: 55

SECTOR_56
type: Class
title: Administrative and Support and Waste Management
subclass of: NAICSSectorEnum
definition: Establishments providing administrative and support services
activities: administrative services, waste management, remediation
naics code: 56
support function: business support services

SECTOR_61
type: Class
title: Educational Services
subclass of: NAICSSectorEnum
definition: Establishments providing educational instruction
activities: schools, colleges, training programs
naics code: 61
public private: public and private education

SECTOR_62
type: Class
title: Health Care and Social Assistance
subclass of: NAICSSectorEnum
definition: Establishments providing health care and social assistance
activities: hospitals, medical practices, social assistance
essential services: essential public services
naics code: 62

SECTOR_71
type: Class
title: Arts, Entertainment, and Recreation
subclass of: NAICSSectorEnum
definition: Establishments in arts, entertainment, and recreation
activities: performing arts, spectator sports, museums, recreation
discretionary: discretionary consumer spending
naics code: 71

SECTOR_72
type: Class
title: Accommodation and Food Services
subclass of: NAICSSectorEnum
definition: Establishments providing accommodation and food services
activities: hotels, restaurants, food services
consumer services: consumer hospitality services
naics code: 72

SECTOR_81
type: Class
title: Other Services (except Public Administration)
subclass of: NAICSSectorEnum
definition: Establishments providing other services
activities: repair, personal care, religious organizations
diverse: diverse service activities
naics code: 81

SECTOR_92
type: Class
title: Public Administration
subclass of: NAICSSectorEnum
definition: Government establishments
activities: executive, legislative, judicial, public safety
naics code: 92
sector: government sector

ACTINIUM_SERIES
type: Class
title: Actinium (Uranium-235) decay series
subclass of: NORMEnum
definition: The actinium decay series starting from U-235 and ending with stable Pb-207.
end product: Pb-207
parent: U-235

POTASSIUM_40_PRIMORDIAL
type: Class
title: Potassium-40
subclass of: NORMEnum
definition: Primordial radionuclide present in all potassium-bearing minerals and biological tissues.
type: primordial
ubiquity: present in all potassium

THORIUM_SERIES
type: Class
title: Thorium-232 decay series
subclass of: NORMEnum
definition: The thorium decay series starting from Th-232 and ending with stable Pb-208. Includes Ra-228, Rn-220 (thoron), and other isotopes.
end product: Pb-208
key members: Ra-228, Rn-220, Pb-212
parent: Th-232

URANIUM_SERIES
type: Class
title: Uranium-238 decay series
subclass of: NORMEnum
definition: The uranium decay series starting from U-238 and ending with stable Pb-206. Includes Ra-226, Rn-222, Po-210, and other isotopes.
end product: Pb-206
key members: Ra-226, Rn-222, Po-210, Pb-210
parent: U-238

CLASS_A
type: Class
title: Class A Low-Level Waste
subclass of: NRCWasteClassEnum
definition: Lowest radioactivity waste suitable for shallow land burial
concentration limits: lowest of three classes
disposal method: shallow land burial
segregation requirements: minimal
typical sources: medical, industrial, power plants
waste form requirements: none

CLASS_B
type: Class
title: Class B Low-Level Waste
subclass of: NRCWasteClassEnum
definition: Intermediate radioactivity requiring waste form stability
concentration limits: intermediate
disposal method: shallow land burial
institutional control: 100 years minimum
segregation requirements: from Class A
waste form requirements: structural stability

CLASS_C
type: Class
title: Class C Low-Level Waste
subclass of: NRCWasteClassEnum
definition: Highest concentration suitable for shallow land burial
concentration limits: highest for shallow burial
disposal method: shallow land burial
institutional control: 100 years minimum
intruder barriers: required
segregation requirements: enhanced
waste form requirements: structural stability

GREATER_THAN_CLASS_C
type: Class
title: Greater Than Class C Waste (GTCC)
subclass of: NRCWasteClassEnum
alternative label: GTCC
definition: Waste exceeding Class C limits, generally unsuitable for shallow burial
concentration limits: exceeds Class C
deep disposal: may be required
disposal method: case-by-case evaluation
nrc evaluation: required
shallow burial: generally not acceptable

NTPCarcinogenicityGroup
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: NTP Carcinogenicity Group
status: STANDARD
subclass of: CarcinogenicitySchemaEnum
union of: KNOWN_CARCINOGEN
union of: RAHC
definition: U.S. National Toxicology Program (NTP) Report on Carcinogens classifications. The NTP identifies and discusses agents, substances, mixtures, or exposure circumstances that may pose a carcinogenic hazard to human health.
in scheme: merged
permissible values: KNOWN_CARCINOGEN
permissible values: RAHC
publishers: https://ntp.niehs.nih.gov
source: https://ntp.niehs.nih.gov/go/roc
source domain: environmental_health
source schema: carcinogenicity
stewards: https://ntp.niehs.nih.gov

KNOWN_CARCINOGEN
type: Class
title: Known To Be Human Carcinogen
subclass of: NTPCarcinogenicityGroup
definition: There is sufficient evidence of carcinogenicity from studies in humans, which indicates a causal relationship between exposure to the agent and human cancer.
abbreviation: K
evidence: sufficient human evidence
examples: arsenic, asbestos, benzene, vinyl chloride

RAHC
type: Class
title: Reasonably Anticipated To Be Human Carcinogen
subclass of: NTPCarcinogenicityGroup
definition: There is limited evidence of carcinogenicity from studies in humans, which indicates that causal interpretation is credible but alternative explanations cannot be ruled out, OR there is sufficient evidence of carcinogenicity from studies in experimental animals.
abbreviation: RAHC
evidence: limited human or sufficient animal evidence
examples: lead compounds, styrene, trichloroethylene

NANOFIBER
type: Class
subclass of: NanostructureMorphologyEnum
definition: Fiber with nanoscale diameter
diameter: <1000 nm
dimensions: 1D

NANOSHEET
type: Class
subclass of: NanostructureMorphologyEnum
definition: Two-dimensional nanostructure
dimensions: 2D
thickness: <100 nm

NANOWIRE
type: Class
subclass of: NanostructureMorphologyEnum
definition: Wire with nanoscale diameter
diameter: <100 nm
dimensions: 1D

AMQP
type: Class
subclass of: NetworkProtocolEnum
definition: Advanced Message Queuing Protocol
layer: application
port: 5672
use: message queuing

DHCP
type: Class
subclass of: NetworkProtocolEnum
definition: Dynamic Host Configuration Protocol
layer: application
port: 67, 68
use: IP assignment

DNS
type: Class
subclass of: NetworkProtocolEnum
definition: Domain Name System
layer: application
port: 53
use: name resolution

FTP
type: Class
subclass of: NetworkProtocolEnum
definition: File Transfer Protocol
layer: application
port: 21
use: file transfer

GRPC
type: Class
subclass of: NetworkProtocolEnum
definition: gRPC Remote Procedure Call
transport: HTTP/2
use: RPC framework

HTTP
type: Class
subclass of: NetworkProtocolEnum
definition: Hypertext Transfer Protocol
layer: application
port: 80
version: 1.0, 1.1, 2, 3

HTTPS
type: Class
subclass of: NetworkProtocolEnum
definition: HTTP Secure
encryption: TLS/SSL
layer: application
port: 443

IMAP
type: Class
subclass of: NetworkProtocolEnum
definition: Internet Message Access Protocol
layer: application
port: 143, 993
use: email access

MQTT
type: Class
subclass of: NetworkProtocolEnum
definition: Message Queuing Telemetry Transport
layer: application
port: 1883, 8883
use: IoT messaging

POP3
type: Class
subclass of: NetworkProtocolEnum
definition: Post Office Protocol version 3
layer: application
port: 110, 995
use: email retrieval

SFTP
type: Class
subclass of: NetworkProtocolEnum
definition: SSH File Transfer Protocol
encryption: SSH
layer: application
port: 22

SMTP
type: Class
subclass of: NetworkProtocolEnum
definition: Simple Mail Transfer Protocol
layer: application
port: 25, 587
use: email sending

SSH
type: Class
subclass of: NetworkProtocolEnum
definition: Secure Shell
layer: application
port: 22
use: secure remote access

TCP
type: Class
subclass of: NetworkProtocolEnum
definition: Transmission Control Protocol
layer: transport
type: connection-oriented

TELNET
type: Class
subclass of: NetworkProtocolEnum
definition: Telnet protocol
layer: application
port: 23
security: unencrypted

UDP
type: Class
subclass of: NetworkProtocolEnum
definition: User Datagram Protocol
layer: transport
type: connectionless

WEBSOCKET
type: Class
subclass of: NetworkProtocolEnum
definition: WebSocket protocol
layer: application
port: 80, 443
use: bidirectional communication

INTERMEDIATE
type: Class
title: Intermediate Risk
subclass of: NeuroblastomaRiskGroup
definition: Intermediate risk neuroblastoma requiring multimodal treatment including chemotherapy.
expected efs: 50-75%

LOW
type: Class
title: Low Risk
subclass of: NeuroblastomaRiskGroup
definition: Low risk neuroblastoma with favorable prognosis. Treatment may include surgery alone or observation.
expected efs: >75%

VERY_LOW
type: Class
title: Very Low Risk
subclass of: NeuroblastomaRiskGroup
definition: Very low risk neuroblastoma with excellent prognosis. Typically includes L1 tumors and MS without MYCN amplification.
expected efs: >85%

BUSINESS
type: Class
title: Business
subclass of: NewsTopicCategoryEnum
alternative label: economy
alternative label: finance
definition: Business, finance, and economic news

ENTERTAINMENT
type: Class
title: Entertainment
subclass of: NewsTopicCategoryEnum
alternative label: showbiz
definition: Entertainment and celebrity news

HEALTH
type: Class
title: Health
subclass of: NewsTopicCategoryEnum
alternative label: medical
definition: Health, medicine, and wellness news

LOCAL
type: Class
title: Local
subclass of: NewsTopicCategoryEnum
alternative label: regional
definition: Local and regional news

POLITICS
type: Class
title: Politics
subclass of: NewsTopicCategoryEnum
definition: Political news and government affairs

SCIENCE
type: Class
title: Science
subclass of: NewsTopicCategoryEnum
definition: Scientific discoveries and research

SPORTS
type: Class
title: Sports
subclass of: NewsTopicCategoryEnum
definition: Sports news and events

TECHNOLOGY
type: Class
title: Technology
subclass of: NewsTopicCategoryEnum
alternative label: IT
alternative label: tech
definition: Technology and computing news

WORLD
type: Class
title: World
subclass of: NewsTopicCategoryEnum
alternative label: global
alternative label: international
definition: International news and events

COMMERCIAL_POWER_PLANT
type: Class
title: Commercial Nuclear Power Plant
subclass of: NuclearFacilityTypeEnum
definition: Large-scale commercial reactor for electricity generation
operator type: utility company
power output: typically 300-1600 MWe
primary purpose: electricity generation
regulatory oversight: extensive

CONVERSION_FACILITY
type: Class
title: Conversion Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for converting yellowcake to UF6
input material: uranium concentrate (U3O8)
output product: uranium hexafluoride (UF6)
process: chemical conversion

DECOMMISSIONING_SITE
type: Class
title: Decommissioning Site
subclass of: NuclearFacilityTypeEnum
definition: Nuclear facility undergoing dismantlement
activities: decontamination, demolition
duration: typically 10-50 years
facility status: being dismantled

ENRICHMENT_FACILITY
type: Class
title: Enrichment Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for increasing U-235 concentration
input material: natural UF6
output product: enriched UF6
process: isotope separation (centrifuge, diffusion)
sensitive technology: proliferation-sensitive

FUEL_FABRICATION_FACILITY
type: Class
title: Fuel Fabrication Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for manufacturing nuclear fuel assemblies
input material: enriched UF6
output product: fuel assemblies
process: pellet and rod manufacturing

GEOLOGICAL_REPOSITORY
type: Class
title: Geological Repository
subclass of: NuclearFacilityTypeEnum
definition: Deep underground facility for permanent waste disposal
depth: typically >300 meters underground
storage duration: permanent (thousands of years)
waste types: high-level waste, spent fuel

INTERIM_STORAGE_FACILITY
type: Class
title: Interim Storage Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for temporary storage of nuclear materials
storage duration: intermediate term (5-100 years)
storage medium: pools, dry casks
typical materials: spent fuel, waste

NAVAL_REACTOR
type: Class
title: Naval Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor for ship or submarine propulsion
compactness: highly compact design
fuel enrichment: typically HEU
operation mode: mobile platform
primary purpose: vessel propulsion

NUCLEAR_LABORATORY
type: Class
title: Nuclear Laboratory
subclass of: NuclearFacilityTypeEnum
definition: Laboratory facility handling radioactive materials
activities: research, analysis, small-scale production
materials: various radioactive substances
scale: laboratory scale

PRODUCTION_REACTOR
type: Class
title: Production Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor for producing nuclear materials
operation mode: specialized for production
primary purpose: isotope or material production
products: tritium, plutonium, medical isotopes

PROTOTYPE_REACTOR
type: Class
title: Prototype Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor for demonstrating new technology
innovation focus: new reactor concepts
primary purpose: technology demonstration
scale: smaller than commercial

RADIOISOTOPE_PRODUCTION_FACILITY
type: Class
title: Radioisotope Production Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for producing medical and industrial isotopes
market: medical and industrial applications
production methods: reactor irradiation, accelerator
products: medical isotopes, industrial tracers

REPROCESSING_FACILITY
type: Class
title: Reprocessing Facility
subclass of: NuclearFacilityTypeEnum
definition: Facility for separating spent fuel components
input material: spent nuclear fuel
output products: uranium, plutonium, waste
process: chemical separation (PUREX, UREX+)
proliferation sensitivity: high

RESEARCH_REACTOR
type: Class
title: Research Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor designed for research, training, and isotope production
fuel type: various, often HEU or LEU
neutron flux: optimized for research needs
power output: typically <100 MWt
primary purpose: research, training, isotope production

SPACE_REACTOR
type: Class
title: Space Nuclear Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor designed for space applications
cooling: radiative cooling
mass constraints: extremely lightweight
power output: typically <10 MWt
primary purpose: space power or propulsion

TEST_REACTOR
type: Class
title: Test Reactor
subclass of: NuclearFacilityTypeEnum
definition: Reactor for testing materials and components
neutron spectrum: variable for testing needs
primary purpose: materials and component testing
test capabilities: irradiation testing

URANIUM_MILL
type: Class
title: Uranium Mill
subclass of: NuclearFacilityTypeEnum
definition: Facility for processing uranium ore into yellowcake
input material: uranium ore
output product: uranium concentrate (U3O8)
process: chemical extraction and purification

URANIUM_MINE
type: Class
title: Uranium Mine
subclass of: NuclearFacilityTypeEnum
definition: Facility for extracting uranium ore
extraction method: underground or open pit
processing: may include milling
product: uranium ore

AGE_DATING
type: Class
subclass of: NuclearForensicsMethodType
definition: Determination of the time since last chemical purification of nuclear material using parent-daughter ratios

RADIOCHEMICAL_SEPARATION
type: Class
subclass of: NuclearForensicsMethodType
definition: Chemical separation of radionuclides from a sample matrix for individual measurement

NuclearForensicsSchemaEnum
type: Class
subclass of: EnergyDomainEnum
definition: Schema-level enum for nuclear_forensics in energy
in scheme: merged
source file: energy/nuclear/nuclear_forensics.yaml

CONVERSION
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Converting yellowcake to uranium hexafluoride (UF6)

ENRICHMENT
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Increasing U-235 concentration in uranium

FINAL_DISPOSAL
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Permanent disposal of nuclear waste

FUEL_FABRICATION
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Manufacturing nuclear fuel assemblies

INTERIM_STORAGE
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Temporary storage of spent nuclear fuel

MILLING
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Processing uranium ore into yellowcake (U3O8)

MINING
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Uranium ore mining and extraction

REACTOR_OPERATION
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Nuclear fission in reactor core

REPROCESSING
type: Class
subclass of: NuclearFuelCycleStageEnum
definition: Chemical separation of useful materials from spent fuel

ENRICHED_URANIUM
type: Class
subclass of: NuclearFuelFormEnum
definition: Uranium with increased U-235 concentration

FUEL_ASSEMBLIES
type: Class
subclass of: NuclearFuelFormEnum
definition: Bundled fuel rods ready for reactor loading

FUEL_PELLETS
type: Class
subclass of: NuclearFuelFormEnum
definition: Sintered uranium dioxide pellets

FUEL_RODS
type: Class
subclass of: NuclearFuelFormEnum
definition: Zircaloy tubes containing fuel pellets

MIXED_OXIDE_FUEL
type: Class
subclass of: NuclearFuelFormEnum
definition: MOX fuel containing plutonium and uranium oxides

SPENT_FUEL
type: Class
subclass of: NuclearFuelFormEnum
definition: Used nuclear fuel removed from reactor

URANIUM_DIOXIDE
type: Class
subclass of: NuclearFuelFormEnum
definition: Ceramic uranium fuel pellets (UO2)

URANIUM_HEXAFLUORIDE
type: Class
subclass of: NuclearFuelFormEnum
definition: Gaseous uranium compound (UF6) used for enrichment

URANIUM_ORE
type: Class
subclass of: NuclearFuelFormEnum
definition: Natural uranium ore containing uranium minerals

YELLOWCAKE
type: Class
subclass of: NuclearFuelFormEnum
definition: Uranium oxide concentrate (U3O8)

CARBIDE_FUEL
type: Class
title: Carbide Nuclear Fuel
subclass of: NuclearFuelTypeEnum
definition: Uranium or plutonium carbide fuel
chemical form: carbide
melting point: very high
typical use: advanced reactors

HIGHLY_ENRICHED_URANIUM
type: Class
title: Highly Enriched Uranium (HEU)
subclass of: NuclearFuelTypeEnum
alternative label: HEU
definition: Uranium enriched to 20% or more U-235
iaea category: direct use material
proliferation risk: high
typical use: research reactors, naval propulsion
u235 content: ≥20%

HIGH_ASSAY_LEU
type: Class
title: High-Assay Low Enriched Uranium (HALEU)
subclass of: NuclearFuelTypeEnum
alternative label: HALEU
alternative label: LEU+
definition: Uranium enriched to 5%-20% U-235
proliferation risk: moderate
typical use: advanced reactors, SMRs
u235 content: 5-20%

LIQUID_FUEL
type: Class
title: Liquid Nuclear Fuel
subclass of: NuclearFuelTypeEnum
definition: Fuel dissolved in liquid medium
phase: liquid
reprocessing: online
typical use: molten salt reactors

LOW_ENRICHED_URANIUM
type: Class
title: Low Enriched Uranium (LEU)
subclass of: NuclearFuelTypeEnum
alternative label: LEU
definition: Uranium enriched to 0.7%-20% U-235
iaea category: indirect use material
proliferation risk: low
typical use: commercial power reactors
u235 content: 0.7-20%

METALLIC_FUEL
type: Class
title: Metallic Nuclear Fuel
subclass of: NuclearFuelTypeEnum
definition: Fuel in metallic form
form: metal alloy
thermal conductivity: high
typical use: fast reactors

MOX_FUEL
type: Class
title: Mixed Oxide Fuel
subclass of: NuclearFuelTypeEnum
alternative label: MOX
alternative label: Mixed Oxide
definition: Mixture of plutonium and uranium oxides
composition: UO2 + PuO2
plutonium content: 3-10%
recycling: enables plutonium recycling
typical use: thermal reactors

NITRIDE_FUEL
type: Class
title: Nitride Nuclear Fuel
subclass of: NuclearFuelTypeEnum
definition: Uranium or plutonium nitride fuel
chemical form: nitride
density: high
typical use: fast reactors

REACTOR_GRADE_PLUTONIUM
type: Class
title: Reactor-Grade Plutonium
subclass of: NuclearFuelTypeEnum
alternative label: RGPu
definition: Plutonium with high Pu-240 content from spent fuel
pu239 content: <93%
pu240 content: >7%
source: spent nuclear fuel
typical use: MOX fuel

TRISO_FUEL
type: Class
title: Tri-structural Isotropic Fuel
subclass of: NuclearFuelTypeEnum
alternative label: TRISO
definition: Coated particle fuel with multiple containment layers
containment layers: 4
form: coated particles
meltdown resistance: very high
typical use: HTGR, some SMRs

WEAPONS_GRADE_PLUTONIUM
type: Class
title: Weapons-Grade Plutonium
subclass of: NuclearFuelTypeEnum
alternative label: WGPu
definition: Plutonium with low Pu-240 content
proliferation risk: very high
pu239 content: ≥93%
pu240 content: <7%

WEAPONS_GRADE_URANIUM
type: Class
title: Weapons-Grade Uranium
subclass of: NuclearFuelTypeEnum
alternative label: WGU
definition: Uranium enriched to 90% or more U-235
proliferation risk: very high
typical use: nuclear weapons, some naval reactors
u235 content: ≥90%

AERB
type: Class
title: Atomic Energy Regulatory Board (India)
subclass of: NuclearRegulatoryBodyEnum
definition: Atomic Energy Regulatory Board (India)

ASN
type: Class
title: Nuclear Safety Authority (France)
subclass of: NuclearRegulatoryBodyEnum
definition: Autorité de sûreté nucléaire (France)

CNNC
type: Class
title: China National Nuclear Corporation
subclass of: NuclearRegulatoryBodyEnum
definition: China National Nuclear Corporation

CNSC
type: Class
title: Canadian Nuclear Safety Commission
subclass of: NuclearRegulatoryBodyEnum
definition: Canadian Nuclear Safety Commission

ENSI
type: Class
title: Swiss Federal Nuclear Safety Inspectorate
subclass of: NuclearRegulatoryBodyEnum
definition: Swiss Federal Nuclear Safety Inspectorate

IAEA
type: Class
title: International Atomic Energy Agency
subclass of: NuclearRegulatoryBodyEnum
definition: International Atomic Energy Agency

KAERI
type: Class
title: Korea Atomic Energy Research Institute
subclass of: NuclearRegulatoryBodyEnum
definition: Korea Atomic Energy Research Institute

NISA
type: Class
title: Nuclear and Industrial Safety Agency (Japan)
subclass of: NuclearRegulatoryBodyEnum
definition: Nuclear and Industrial Safety Agency (Japan)

NRC
type: Class
title: Nuclear Regulatory Commission (US)
subclass of: NuclearRegulatoryBodyEnum
definition: US Nuclear Regulatory Commission

ONR
type: Class
title: Office for Nuclear Regulation (UK)
subclass of: NuclearRegulatoryBodyEnum
definition: Office for Nuclear Regulation (UK)

ROSATOM
type: Class
title: State Atomic Energy Corporation (Russia)
subclass of: NuclearRegulatoryBodyEnum
definition: State Atomic Energy Corporation (Russia)

SKI
type: Class
title: Swedish Nuclear Power Inspectorate
subclass of: NuclearRegulatoryBodyEnum
definition: Swedish Nuclear Power Inspectorate

STUK
type: Class
title: Radiation and Nuclear Safety Authority (Finland)
subclass of: NuclearRegulatoryBodyEnum
definition: Radiation and Nuclear Safety Authority (Finland)

CAPPING
type: Class
subclass of: NuclearRemediationType
definition: Placing an engineered barrier over contaminated material to prevent migration and exposure

CHEMICAL_OXIDATION
type: Class
subclass of: NuclearRemediationType
definition: Using chemical oxidants to destroy or transform organic contaminants at nuclear sites

ELECTROKINETIC_REMEDIATION
type: Class
subclass of: NuclearRemediationType
definition: Applying electric fields to move and concentrate contaminants in soil for removal

GROUNDWATER_PUMP_AND_TREAT
type: Class
subclass of: NuclearRemediationType
definition: Pumping contaminated groundwater to the surface for treatment and reinjection

IN_SITU_BIOREMEDIATION
type: Class
subclass of: NuclearRemediationType
definition: Using microorganisms in place to degrade or immobilize radioactive contaminants

MONITORED_NATURAL_ATTENUATION
type: Class
subclass of: NuclearRemediationType
definition: Monitoring natural processes that reduce contaminant concentrations without active intervention

PHYTOREMEDIATION
type: Class
subclass of: NuclearRemediationType
definition: Using plants to extract, contain, or degrade radioactive contaminants from soil and water

SOIL_EXCAVATION
type: Class
subclass of: NuclearRemediationType
definition: Physical removal and disposal of contaminated soil

STABILIZATION
type: Class
subclass of: NuclearRemediationType
definition: Chemical or physical treatment to reduce the mobility of contaminants in soil or waste

VITRIFICATION
type: Class
subclass of: NuclearRemediationType
definition: Immobilizing radioactive waste by incorporating it into a glass matrix

CATEGORY_I
type: Class
title: Category I Nuclear Material
subclass of: NuclearSecurityCategoryEnum
definition: Material that can be used directly to manufacture nuclear explosive devices
direct use: true
examples: HEU ≥20%, Pu ≥2kg, U-233 ≥2kg
physical protection: multiple independent physical barriers
proliferation risk: highest
protection requirements: maximum

CATEGORY_II
type: Class
title: Category II Nuclear Material
subclass of: NuclearSecurityCategoryEnum
definition: Material requiring further processing to manufacture nuclear explosive devices
direct use: requires processing
examples: HEU <20% but >5%, natural uranium >500kg
physical protection: significant barriers required
proliferation risk: moderate
protection requirements: substantial

CATEGORY_III
type: Class
title: Category III Nuclear Material
subclass of: NuclearSecurityCategoryEnum
definition: Material posing radiation hazard but minimal proliferation risk
direct use: false
examples: natural uranium 10-500kg, depleted uranium
physical protection: basic measures sufficient
proliferation risk: low
protection requirements: basic

CATEGORY_IV
type: Class
title: Category IV Nuclear Material
subclass of: NuclearSecurityCategoryEnum
definition: Material with minimal security significance
direct use: false
examples: small quantities of natural uranium
proliferation risk: minimal
protection requirements: administrative

AIRCRAFT_CARRIER
type: Class
title: Nuclear Aircraft Carrier
subclass of: NuclearShipTypeEnum
definition: Large naval vessel with nuclear propulsion and aircraft operations
mission: power projection, aircraft operations
propulsion: nuclear steam turbine
reactor count: typically 2
size: very large (>80,000 tons)

CRUISER
type: Class
title: Nuclear Cruiser
subclass of: NuclearShipTypeEnum
definition: Large surface combatant with nuclear propulsion
mission: escort, surface warfare
propulsion: nuclear steam turbine
size: large surface vessel
status: mostly retired

ICEBREAKER
type: Class
title: Nuclear Icebreaker
subclass of: NuclearShipTypeEnum
definition: Vessel designed to break ice using nuclear power
mission: ice breaking, Arctic operations
operational environment: polar regions
propulsion: nuclear steam turbine or electric
reactor count: 1-3

MERCHANT_SHIP
type: Class
title: Nuclear Merchant Ship
subclass of: NuclearShipTypeEnum
definition: Commercial cargo vessel with nuclear propulsion
commercial viability: limited due to costs
examples: NS Savannah, few others
mission: cargo transport
propulsion: nuclear steam turbine

RESEARCH_VESSEL
type: Class
title: Nuclear Research Vessel
subclass of: NuclearShipTypeEnum
definition: Ship designed for oceanographic research with nuclear power
duration: extended operations without refueling
examples: limited number built
mission: scientific research
propulsion: nuclear

SUBMARINE
type: Class
title: Nuclear Submarine
subclass of: NuclearShipTypeEnum
definition: Underwater vessel with nuclear propulsion
mission: various (attack, ballistic missile, cruise missile)
operational environment: submerged
propulsion: nuclear steam turbine
reactor count: typically 1

ENVIRONMENTAL_RELEASE
type: Class
subclass of: NuclearThreatCategoryType
definition: Unauthorized or accidental release of radioactive material into the environment

NUCLEAR_FACILITY_SABOTAGE
type: Class
subclass of: NuclearThreatCategoryType
definition: Deliberate sabotage of a nuclear facility to cause radiological release

NUCLEAR_MATERIAL_THEFT
type: Class
subclass of: NuclearThreatCategoryType
definition: Theft or diversion of nuclear or radioactive material from authorized control

NUCLEAR_SMUGGLING
type: Class
subclass of: NuclearThreatCategoryType
definition: Illicit trafficking and transport of nuclear or radioactive materials across borders

OWL_2_DL
type: Class
title: OWL 2 DL
subclass of: OWLProfileEnum
definition: OWL 2 DL (Description Logic) - full expressiveness while maintaining computational completeness and decidability. Maximum expressiveness without sacrificing decidability.
complexity: NExpTime
use case: general purpose ontologies requiring high expressiveness

OWL_2_EL
type: Class
title: OWL 2 EL
subclass of: OWLProfileEnum
definition: OWL 2 EL (Existential Language) - optimized for applications using very large ontologies with basic relationships. Provides polynomial time reasoning.
complexity: polynomial time
use case: large biomedical ontologies, SNOMED CT

OWL_2_FULL
type: Class
title: OWL 2 Full
subclass of: OWLProfileEnum
definition: OWL 2 Full - maximum expressiveness with no restrictions, but reasoning is undecidable. Allows full RDF capabilities.
complexity: undecidable
use case: maximum flexibility, no guaranteed reasoning

OWL_2_QL
type: Class
title: OWL 2 QL
subclass of: OWLProfileEnum
definition: OWL 2 QL (Query Language) - optimized for query answering over large data repositories. Based on DL-Lite family.
complexity: LogSpace data complexity
use case: ontology-based data access, database integration

OWL_2_RL
type: Class
title: OWL 2 RL
subclass of: OWLProfileEnum
definition: OWL 2 RL (Rule Language) - optimized for rule-based reasoning and can be implemented using rule engines. Compatible with RDF Schema.
complexity: polynomial time
use case: business rules, policy systems

BRONZE
type: Class
subclass of: OpenAccessType
definition: Free to read but no license

CLOSED
type: Class
subclass of: OpenAccessType
definition: Closed access/subscription only

DIAMOND
type: Class
subclass of: OpenAccessType
definition: Diamond/platinum OA (no fees)

EMBARGO
type: Class
subclass of: OpenAccessType
definition: Under embargo period

GOLD
type: Class
subclass of: OpenAccessType
definition: Gold open access (published OA)

GREEN
type: Class
subclass of: OpenAccessType
definition: Green open access (self-archived)

HYBRID
type: Class
subclass of: OpenAccessType
definition: Hybrid journal with OA option

ARCHIVED
type: Class
title: Archived
subclass of: OpenSourceMaturityLevel
definition: No longer actively maintained

DECLINING
type: Class
title: Declining
subclass of: OpenSourceMaturityLevel
definition: Decreasing activity and maintenance

EMERGING
type: Class
title: Emerging
subclass of: OpenSourceMaturityLevel
definition: Gaining traction and contributors

ESTABLISHED
type: Class
title: Established
subclass of: OpenSourceMaturityLevel
definition: Stable with active community

EXPERIMENTAL
type: Class
title: Experimental
subclass of: OpenSourceMaturityLevel
definition: Early experimental project

MATURE
type: Class
title: Mature
subclass of: OpenSourceMaturityLevel
definition: Well-established with proven governance

AGILE_OPERATIONS
type: Class
title: Agile Operations
subclass of: OperationalModelEnum
definition: Flexible and responsive operational approach
adaptation: rapid adaptation
agility: operational agility
iteration: iterative improvement
responsiveness: market responsiveness

CENTRALIZED_OPERATIONS
type: Class
title: Centralized Operations
subclass of: OperationalModelEnum
definition: Centralized operational control and decision-making
control: centralized control
coordination: central coordination
efficiency: operational efficiency
standardization: standardized processes

DECENTRALIZED_OPERATIONS
type: Class
title: Decentralized Operations
subclass of: OperationalModelEnum
definition: Distributed operational control and autonomy
autonomy: local autonomy
empowerment: local empowerment
flexibility: operational flexibility
responsiveness: market responsiveness

DIGITAL_OPERATIONS
type: Class
title: Digital Operations
subclass of: OperationalModelEnum
definition: Technology-enabled and digital-first operations
automation: process automation
data driven: data-driven operations
scalability: digital scalability
technology: digital technology enabled

HYBRID_OPERATIONS
type: Class
title: Hybrid Operations
subclass of: OperationalModelEnum
definition: Combination of centralized and decentralized elements
balance: balance between control and flexibility
combination: mixed centralized and decentralized
complexity: increased complexity
optimization: situational optimization

LEAN_OPERATIONS
type: Class
title: Lean Operations
subclass of: OperationalModelEnum
definition: Waste elimination and value-focused operations
continuous improvement: continuous improvement
efficiency: operational efficiency
value: value stream focus
waste: waste elimination

NETWORK_OPERATIONS
type: Class
title: Network Operations
subclass of: OperationalModelEnum
definition: Collaborative network of partners and suppliers
collaboration: collaborative operations
coordination: network coordination
flexibility: network flexibility
network: partner and supplier network

OUTSOURCED_OPERATIONS
type: Class
title: Outsourced Operations
subclass of: OperationalModelEnum
definition: External service provider operational model
cost: cost optimization
expertise: specialized expertise
focus: core competency focus
provider: external service providers

PLATFORM_OPERATIONS
type: Class
title: Platform Operations
subclass of: OperationalModelEnum
definition: Platform-based business operational model
ecosystem: business ecosystem
network effects: network effects
platform: platform-based operations
scalability: scalable operations

SHARED_SERVICES
type: Class
title: Shared Services
subclass of: OperationalModelEnum
definition: Centralized services shared across business units
cost effectiveness: cost-effective service delivery
efficiency: scale efficiency
sharing: shared service delivery
standardization: service standardization

EMERGENCY_RESPONSE
type: Class
title: Emergency Response Procedure
subclass of: OperationalProcedureEnum
definition: Response to emergency conditions
classification: event classification
coordination: with offsite authorities
mitigation: protective action implementation
notification: offsite notification

MAINTENANCE_PROCEDURE
type: Class
title: Maintenance Procedure
subclass of: OperationalProcedureEnum
definition: Systematic approach to equipment maintenance
documentation: maintenance records
safety tagging: equipment isolation
testing: post-maintenance testing
work control: work order control process

RADIOLOGICAL_PROTECTION
type: Class
title: Radiological Protection Procedure
subclass of: OperationalProcedureEnum
definition: Procedures for radiation protection
contamination control: contamination prevention
dose control: personnel dose limits
emergency: radiological emergency response
monitoring: radiation monitoring

REFUELING_PROCEDURE
type: Class
title: Refueling Procedure
subclass of: OperationalProcedureEnum
definition: Procedure for fuel handling and replacement
criticality control: strict criticality prevention
documentation: detailed records
handling: underwater fuel handling
verification: independent verification

SECURITY_PROCEDURE
type: Class
title: Security Procedure
subclass of: OperationalProcedureEnum
definition: Physical security and access control procedures
access control: personnel access authorization
coordination: with law enforcement
detection: intrusion detection systems
response: security force response

SHUTDOWN_PROCEDURE
type: Class
title: Reactor Shutdown Procedure
subclass of: OperationalProcedureEnum
definition: Systematic procedure for shutting down reactor
control rod insertion: gradual or rapid
cooling: controlled cooldown
systems: systematic system shutdown
verification: shutdown margin verification

STARTUP_PROCEDURE
type: Class
title: Reactor Startup Procedure
subclass of: OperationalProcedureEnum
definition: Systematic procedure for bringing reactor to power
authorization: management authorization required
duration: hours to days
phases: multiple phases with hold points
testing: system testing at each phase

SURVEILLANCE_TESTING
type: Class
title: Surveillance Testing
subclass of: OperationalProcedureEnum
definition: Regular testing of safety systems
corrective action: if performance degraded
documentation: test result documentation
frequency: specified by technical specifications
scope: functionality verification

OperationsSchemaEnum
type: Class
subclass of: LabAutomationDomainEnum
definition: Schema-level enum for operations in lab_automation
in scheme: merged
source file: lab_automation/operations.yaml

ABSORBING
type: Class
title: Absorbing
subclass of: OpticalPropertyEnum
definition: Absorbs most incident light

FLUORESCENT
type: Class
title: Fluorescent
subclass of: OpticalPropertyEnum
definition: Emits light when excited by radiation

PHOSPHORESCENT
type: Class
title: Phosphorescent
subclass of: OpticalPropertyEnum
definition: Continues to emit light after excitation stops

REFLECTIVE
type: Class
title: Reflective
subclass of: OpticalPropertyEnum
definition: Reflects most incident light

TRANSLUCENT
type: Class
title: Translucent
subclass of: OpticalPropertyEnum
definition: Allows light to pass through but with significant scattering

HIGH_GRADE
type: Class
subclass of: OreGrade
definition: High-grade ore
concentration: high
processing: minimal required

LOW_GRADE
type: Class
subclass of: OreGrade
definition: Low-grade ore
concentration: low
processing: extensive required

MARGINAL
type: Class
subclass of: OreGrade
definition: Marginal ore
economics: borderline profitable

MEDIUM_GRADE
type: Class
subclass of: OreGrade
definition: Medium-grade ore
concentration: moderate

SUB_ECONOMIC
type: Class
subclass of: OreGrade
definition: Sub-economic ore
economics: not currently profitable

WASTE
type: Class
subclass of: OreGrade
definition: Waste rock
concentration: below cutoff

DIVISIONAL
type: Class
title: Divisional Structure
subclass of: OrganizationalStructureEnum
definition: Organization by product lines, markets, or geography
autonomy: divisional autonomy
coordination: horizontal coordination
focus: market or product focus
grouping: by products, markets, or geography
responsibility: profit center responsibility

FLAT
type: Class
title: Flat Structure
subclass of: OrganizationalStructureEnum
definition: Minimal hierarchical levels with broader spans of control
communication: direct communication
decision making: decentralized decision making
flexibility: high flexibility
levels: few hierarchical levels
span of control: broad spans of control

FUNCTIONAL
type: Class
title: Functional Structure
subclass of: OrganizationalStructureEnum
definition: Organization by business functions or departments
coordination: vertical coordination
efficiency: operational efficiency
expertise: concentrated expertise
grouping: by business function
specialization: functional specialization

HIERARCHICAL
type: Class
title: Hierarchical Structure
subclass of: OrganizationalStructureEnum
definition: Traditional pyramid structure with clear chain of command
authority flow: top-down authority
communication: vertical communication channels
control: centralized control
decision making: centralized decision making
levels: multiple management levels

HYBRID
type: Class
title: Hybrid Structure
subclass of: OrganizationalStructureEnum
definition: Combination of multiple organizational structures
adaptation: adaptable to different needs
combination: multiple structure types
complexity: increased structural complexity
customization: customized to organization needs
flexibility: structural flexibility

MATRIX
type: Class
title: Matrix Structure
subclass of: OrganizationalStructureEnum
definition: Dual reporting relationships combining functional and project lines
authority: shared authority between managers
communication: multidirectional communication
complexity: increased complexity
flexibility: high project flexibility
reporting: dual reporting relationships

NETWORK
type: Class
title: Network Structure
subclass of: OrganizationalStructureEnum
definition: Flexible structure with interconnected relationships
adaptability: high adaptability
boundaries: blurred organizational boundaries
collaboration: extensive collaboration
flexibility: high flexibility
relationships: network of relationships

TEAM_BASED
type: Class
title: Team-Based Structure
subclass of: OrganizationalStructureEnum
definition: Organization around self-managing teams
collaboration: high collaboration
decision making: team-based decision making
flexibility: operational flexibility
management: self-managing teams
unit: teams as basic organizational unit

VIRTUAL
type: Class
title: Virtual Structure
subclass of: OrganizationalStructureEnum
definition: Geographically dispersed organization connected by technology
boundaries: minimal physical boundaries
coordination: virtual coordination
flexibility: location flexibility
location: geographically dispersed
technology: technology-enabled communication

CPY
type: Class
subclass of: OstiAccessLimitation

CUI
type: Class
subclass of: OstiAccessLimitation

ECI
type: Class
subclass of: OstiAccessLimitation

INTL
type: Class
subclass of: OstiAccessLimitation

LRD
type: Class
subclass of: OstiAccessLimitation

NAT
type: Class
subclass of: OstiAccessLimitation

NNPI
type: Class
subclass of: OstiAccessLimitation

OPN
type: Class
subclass of: OstiAccessLimitation

OTHR
type: Class
subclass of: OstiAccessLimitation

OUO
type: Class
subclass of: OstiAccessLimitation

PAT
type: Class
subclass of: OstiAccessLimitation

PDOUO
type: Class
subclass of: OstiAccessLimitation

PDSH
type: Class
subclass of: OstiAccessLimitation

PROP
type: Class
subclass of: OstiAccessLimitation

PROT
type: Class
subclass of: OstiAccessLimitation

UNL
type: Class
subclass of: OstiAccessLimitation

USO
type: Class
subclass of: OstiAccessLimitation

CHORUS
type: Class
subclass of: OstiCollectionType

DOE_GRANT
type: Class
subclass of: OstiCollectionType

DOE_LAB
type: Class
subclass of: OstiCollectionType

Chair
type: Class
subclass of: OstiContributorType

DataCollector
type: Class
subclass of: OstiContributorType

DataCurator
type: Class
subclass of: OstiContributorType

DataManager
type: Class
subclass of: OstiContributorType

Distributor
type: Class
subclass of: OstiContributorType

Editor
type: Class
subclass of: OstiContributorType

HostingInstitution
type: Class
subclass of: OstiContributorType

Other
type: Class
subclass of: OstiContributorType

Producer
type: Class
subclass of: OstiContributorType

ProjectLeader
type: Class
subclass of: OstiContributorType

ProjectManager
type: Class
subclass of: OstiContributorType

ProjectMember
type: Class
subclass of: OstiContributorType

RegistrationAgency
type: Class
subclass of: OstiContributorType

RegistrationAuthority
type: Class
subclass of: OstiContributorType

RelatedPerson
type: Class
subclass of: OstiContributorType

ReviewAssistant
type: Class
subclass of: OstiContributorType

Reviewer
type: Class
subclass of: OstiContributorType

ReviewerExternal
type: Class
subclass of: OstiContributorType

RightsHolder
type: Class
subclass of: OstiContributorType

StatsReviewer
type: Class
subclass of: OstiContributorType

Supervisor
type: Class
subclass of: OstiContributorType

Translator
type: Class
subclass of: OstiContributorType

WorkPackageLeader
type: Class
subclass of: OstiContributorType

BOX
type: Class
subclass of: OstiGeolocationType

POINT
type: Class
subclass of: OstiGeolocationType

POLYGON
type: Class
subclass of: OstiGeolocationType

AUTH_REV
type: Class
subclass of: OstiIdentifierType

CN_DOE
type: Class
subclass of: OstiIdentifierType

CN_NONDOE
type: Class
subclass of: OstiIdentifierType

CODEN
type: Class
subclass of: OstiIdentifierType

DOE_DOCKET
type: Class
subclass of: OstiIdentifierType

EDB
type: Class
subclass of: OstiIdentifierType

ETDE_RN
type: Class
subclass of: OstiIdentifierType

INIS_RN
type: Class
subclass of: OstiIdentifierType

ISBN
type: Class
subclass of: OstiIdentifierType

ISSN
type: Class
subclass of: OstiIdentifierType

LEGACY
type: Class
subclass of: OstiIdentifierType

NSA
type: Class
subclass of: OstiIdentifierType

OPN_ACC
type: Class
subclass of: OstiIdentifierType

OTHER_ID
type: Class
subclass of: OstiIdentifierType

PATENT
type: Class
subclass of: OstiIdentifierType

PROJ_ID
type: Class
subclass of: OstiIdentifierType

PROP_REV
type: Class
subclass of: OstiIdentifierType

REF
type: Class
subclass of: OstiIdentifierType

REL_TRN
type: Class
subclass of: OstiIdentifierType

RN
type: Class
subclass of: OstiIdentifierType

TRN
type: Class
subclass of: OstiIdentifierType

TVI
type: Class
subclass of: OstiIdentifierType

USER_VER
type: Class
subclass of: OstiIdentifierType

WORK_AUTH
type: Class
subclass of: OstiIdentifierType

WORK_PROP
type: Class
subclass of: OstiIdentifierType

OstiMediaLocationType
type: Class
contributor: claude-code
contributor: https://orcid.org/0000-0002-6601-2165
title: OSTI Media Location Type
status: DRAFT
subclass of: OstiRecordSchemaEnum
union of: L
union of: O
definition: Location indicators for OSTI media files and sets.
in scheme: merged
permissible values: L
permissible values: O
source domain: publishing
source schema: osti_record

L
type: Class
subclass of: OstiMediaLocationType

O
type: Class
subclass of: OstiMediaLocationType

AWARD_DOI
type: Class
subclass of: OstiOrganizationIdentifierType

CN_DOE
type: Class
subclass of: OstiOrganizationIdentifierType

CN_NONDOE
type: Class
subclass of: OstiOrganizationIdentifierType

AUTHOR
type: Class
subclass of: OstiOrganizationType

CONTRIBUTING
type: Class
subclass of: OstiOrganizationType

RESEARCHING
type: Class
subclass of: OstiOrganizationType

SPONSOR
type: Class
subclass of: OstiOrganizationType

AUTHOR
type: Class
subclass of: OstiPersonType

CONTACT
type: Class
subclass of: OstiPersonType

CONTRIBUTING
type: Class
subclass of: OstiPersonType

PROT_CE
type: Class
subclass of: OstiPersonType

PROT_RO
type: Class
subclass of: OstiPersonType

RELEASE
type: Class
subclass of: OstiPersonType

SBIZ_BO
type: Class
subclass of: OstiPersonType